Abstract:
:A 76-yr-old male presented with Guillain-Barré syndrome after acute hepatitis B virus infection. Main immunologic features were: (a) high levels of circulating hepatitis B surface antigen-containing immune complexes in serum and cerebrospinal fluid during the acute neurologic syndrome, and (b) clearance of immune-complex material with recovery. Our data indicate that these immune complexes in cerebrospinal fluid reflect leakage from the systemic circulation via a deranged blood-brain barrier and are not generated in the cerebrospinal compartment. Possibly deposition of such immune complexes along nerve structures is important in the immunopathogenesis of some cases of Guillain-Barré syndrome.
journal_name
Gastroenterologyjournal_title
Gastroenterologyauthors
Penner E,Maida E,Mamoli B,Gangl Asubject
Has Abstractpub_date
1982-03-01 00:00:00pages
576-80issue
3eissn
0016-5085issn
1528-0012pii
S0016508582000547journal_volume
82pub_type
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