Prokinetic effects in patients with intestinal gas retention.

abstract：:The intracellular pH (pHi) of isolated hamster intestinal cells was determined with three techniques: the null-point method with digitonin, the distribution of the weak acid 5,5-dimethyloxazolidine-2,4-dione, and the trapped fluorescent indicator 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein. In physiologic saline, ...

journal_title：Gastroenterology

authors： Goré J,Hoinard C

更新日期：1989-10-01 00:00:00

abstract：:A patient with a macroamylase in pleural fluid is described. A diagnosis of recurrent pleural effusion due to chronic relapsing pancreatitis had been made on the basis of hyperamylasemia, high pleural fluid amylase, and abdominal pain. The amylase in the pleural fluid as well as the serum was ultimately characterized ...

journal_title：Gastroenterology

authors： Zimmerman HM,Bank S,Buch P,Katzka I,Lendvai S

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND & AIMS:The ratio of liver size to body weight (hepatostat) is tightly controlled, but little is known about how the physiologic functions of the liver help determine its size. Livers of mice repopulated with human hepatocytes (humanized livers) grow to larger than normal; the human hepatocytes do not recogni...

journal_title：Gastroenterology

authors： Naugler WE,Tarlow BD,Fedorov LM,Taylor M,Pelz C,Li B,Darnell J,Grompe M

更新日期：2015-09-01 00:00:00

abstract：:Pentane, a volatile hydrocarbon, is cleared from inspired air by the rat. We have studied this clearance to learn whether or not it is a function of the liver. Rats were put individually into airtight chambers which contained CO2 absorbent and were connected to an O2 reservoir. Pentane was injected into each chamber a...

journal_title：Gastroenterology

authors： Burk RJ,Ludden TM,Lane JM

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND & AIMS:In the intestines, Toll-like receptor 2 (TLR2) mediates immune responses to pathogens and regulates epithelial barrier function; polymorphisms in TLR2 have been associated with inflammatory bowel disease phenotype. We assessed the effects of TLR2 signaling on the enteric nervous system (ENS) in mice. ...

journal_title：Gastroenterology

authors： Brun P,Giron MC,Qesari M,Porzionato A,Caputi V,Zoppellaro C,Banzato S,Grillo AR,Spagnol L,De Caro R,Pizzuti D,Barbieri V,Rosato A,Sturniolo GC,Martines D,Zaninotto G,Palù G,Castagliuolo I

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND/AIMS:Hepatic osmoreceptors are sensitive to changes in portal blood osmolality and cause variations in plasma antidiuretic hormone and water diuresis, which prevent major systemic osmotic changes. Insensitivity of hepatic osmoreceptors might contribute to maintaining increased plasma levels of antidiuretic h...

journal_title：Gastroenterology

authors： Castellano G,Solis-Herruzo JA,Gonzalez A,Morillas JD,Moreno D,Muñoz T,Larrodera L

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND & AIMS:Oral administration of ursodeoxycholic acid (UDCA) and cholesterol causes bile salt malabsorption; the former by competition for and the latter by down-regulation of ileal bile acid transporters. Because ileectomy in rats induces enterohepatic cycling of bilirubin, the hypothesis that dietary steroids...

journal_title：Gastroenterology

authors： Méndez-Sánchez N,Brink MA,Paigen B,Carey MC

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND & AIMS:Cellular and molecular mechanisms of esophageal ulcer healing remain unexplored. We studied the sequential cellular events and the expression of keratinocyte growth factor (KGF) and its receptor (KGF-R) during the healing of experimental esophageal ulcers. METHODS:Esophageal ulcers were produced in r...

journal_title：Gastroenterology

authors： Baatar D,Kawanaka H,Szabo IL,Pai R,Jones MK,Kitano S,Tarnawski AS

更新日期：2002-02-01 00:00:00

abstract：:To determine the frequency of a sustained remission and to assess the long-term prognosis of relapse and retreatment, 66 patients with severe hepatitis B surface antigen-negative chronic active hepatitis and prolonged follow-up after initial corticosteroid withdrawal (mean, 10 +/- 0.4 yr) were evaluated. Selection of ...

journal_title：Gastroenterology

authors： Czaja AJ,Beaver SJ,Shiels MT

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND & AIMS:MicroRNAs (miRNAs) can promote or inhibit tumor growth and are therefore being developed as targets for cancer therapies. They are diverse not only in the messenger RNAs (mRNA) they target, but in their production; the same hairpin RNA structure can generate mature products from each strand, termed 5p...

journal_title：Gastroenterology

authors： Almeida MI,Nicoloso MS,Zeng L,Ivan C,Spizzo R,Gafà R,Xiao L,Zhang X,Vannini I,Fanini F,Fabbri M,Lanza G,Reis RM,Zweidler-McKay PA,Calin GA

更新日期：2012-04-01 00:00:00

abstract：:Fifteen (2.2%) of 693 patients with cystic fibrosis seen over an 18-year period developed clinical hepatic disease. In 13 patients all symptoms were secondary to portal hypertension. Ten had hypersplenism and 6 had variceal bleeding, including 3 who developed both conditions. All 5 patients who survived the initial ep...

journal_title：Gastroenterology

authors： Stern RC,Stevens DP,Boat TF,Doershuk CF,Izant RJ Jr,Matthews LW

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND & AIMS:We have reported that contrast echocardiography is a sensitive screening test for the hepatopulmonary syndrome (HPS). However, contrast echocardiography lacks specificity because many cirrhotic patients have positive study results with normal arterial blood gases and therefore do not fulfill criteria ...

journal_title：Gastroenterology

authors： Abrams GA,Nanda NC,Dubovsky EV,Krowka MJ,Fallon MB

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND & AIMS:Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) are potent antiviral agents that might have additive or synergistic antiviral activity in treatment of patients with chronic hepatitis B (CHB). We compared the efficacy and safety of ETV monotherapy with those of a combination of ETV and TDF. ME...

journal_title：Gastroenterology

authors： Lok AS,Trinh H,Carosi G,Akarca US,Gadano A,Habersetzer F,Sievert W,Wong D,Lovegren M,Cohen D,Llamoso C

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND & AIMS:Ferroportin disease is characterized by iron overload. It has an autosomal-dominant pattern of inheritance and has been associated with mutations in the SLC40A1 gene, which encodes the cellular iron exporter ferroportin. Since the first description in 2001, about 30 mutations have been reported; the h...

journal_title：Gastroenterology

authors： Le Lan C,Mosser A,Ropert M,Detivaud L,Loustaud-Ratti V,Vital-Durand D,Roget L,Bardou-Jacquet E,Turlin B,David V,Loréal O,Deugnier Y,Brissot P,Jouanolle AM

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND & AIMS:HuR is a RNA-binding factor whose expression is commonly upregulated in some human tumor types. We explored the molecular mechanism underlying HuR elevation and its role in gastric cancer tumorigenesis. METHODS:HuR expression and subcellular localization were determined by polymerase chain reaction, ...

journal_title：Gastroenterology

authors： Kang MJ,Ryu BK,Lee MG,Han J,Lee JH,Ha TK,Byun DS,Chae KS,Lee BH,Chun HS,Lee KY,Kim HJ,Chi SG

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND & AIMS:Pancreatitis starts with primarily sterile local inflammation that induces systemic inflammatory response syndrome, followed by compensatory anti-inflammatory response syndrome (CARS). We investigated the mechanisms of these processes in mice and human serum. METHODS:We induced severe acute pancreati...

journal_title：Gastroenterology

authors： Sendler M,van den Brandt C,Glaubitz J,Wilden A,Golchert J,Weiss FU,Homuth G,De Freitas Chama LL,Mishra N,Mahajan UM,Bossaller L,Völker U,Bröker BM,Mayerle J,Lerch MM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND AIMS:CD4+CD25+Foxp3+ T-regulatory (Treg) cells control immune responses and maintain immune homeostasis. However, under inflammatory conditions, Treg cells produce cytokines that promote inflammation. We investigated production of tumor necrosis factor (TNF) by Treg cells in patients with acute hepatitis...

journal_title：Gastroenterology

authors： Choi YS,Jung MK,Lee J,Choi SJ,Choi SH,Lee HW,Lee JJ,Kim HJ,Ahn SH,Lee DH,Kim W,Park SH,Huh JR,Kim HP,Park JY,Shin EC

更新日期：2018-03-01 00:00:00

abstract：:Human intrinsic factor (IF) is found on the surface of parietal cells at the light microscopic level by immunofluorescence, but there is no direct evidence that IF is synthesized in and secreted from this cell. In order to provide this evidence, IF was localized at the ultrastructural level in human stomach, using an ...

journal_title：Gastroenterology

authors： Levine JS,Nakane PK,Allen RH

更新日期：1980-09-01 00:00:00

abstract：:The diagnosis of inflammatory bowel disease (IBD) with its 2 main subforms, Crohn's disease and ulcerative colitis, is based on clinical, endoscopic, radiologic, and histologic criteria. This paradigm remains unchanged despite the advent of new molecular technologies for the examination of serum proteins and genetic s...

journal_title：Gastroenterology

authors： Nikolaus S,Schreiber S

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND & AIMS:Feeding intolerance because of functional gastrointestinal dysmotility and parenteral nutrition-associated cholestasis (PNAC) are common problems in preterm, very-low-birth-weight (VLBW) infants. This double-blind, randomized, placebo-controlled study aimed to assess the effectiveness of "high-dose" o...

journal_title：Gastroenterology

authors： Ng PC,Lee CH,Wong SP,Lam HS,Liu FY,So KW,Lee CY,Fok TF

更新日期：2007-05-01 00:00:00

abstract：:Decreases in arterial pH markedly increase sodium, chloride, and water absorption in the normal ileum and can reverse ongoing cholera toxin-induced secretion. In the current study we examined whether these effects of pH are evident in other models of ileal secretion, and in a model of increased absorption. Rats were a...

journal_title：Gastroenterology

authors： Charney AN,Ingrassia PM,Thaler SM,Keane MG

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND & AIMS:Recurrence of varices and rebleeding after endoscopic therapy is very common. Data on the prediction of recurrent varices after initial obliteration by endoscopic therapy are few. The aim of this study was to correlate the presence and the size of paraesophageal varices (PEVs) in patients after endosc...

journal_title：Gastroenterology

authors： Leung VK,Sung JJ,Ahuja AT,Tumala IE,Lee YT,Lau JY,Chung SC

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND & AIMS:Acetaminophen toxicity is the most common cause of acute liver failure (ALF) in the United States and Great Britain, but may be underrecognized in certain settings. Acetaminophen-protein adducts are specific biomarkers of drug-related toxicity in animal models and can be measured in tissue or blood sa...

journal_title：Gastroenterology

authors： Davern TJ 2nd,James LP,Hinson JA,Polson J,Larson AM,Fontana RJ,Lalani E,Munoz S,Shakil AO,Lee WM,Acute Liver Failure Study Group.

更新日期：2006-03-01 00:00:00

abstract：:Helicobacter pylori infection has been associated with gastritis, duodenal ulcer, gastric ulcer, and the epidemic form of gastric carcinoma. Eradication of H. pylori infection has proven to be difficult. Recently, combinations of antimicrobial drugs have been shown to eradicate greater than 50% of infections; however,...

journal_title：Gastroenterology

authors： Graham DY,Lew GM,Malaty HM,Evans DG,Evans DJ Jr,Klein PD,Alpert LC,Genta RM

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND & AIMS:Approximately half of the families that fulfill Amsterdam criteria for Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC) do not have evidence of the germline mismatch repair gene mutations that define this syndrome and result in microsatellite instability (MSI). The carcinogenic path...

journal_title：Gastroenterology

authors： Goel A,Xicola RM,Nguyen TP,Doyle BJ,Sohn VR,Bandipalliam P,Rozek LS,Reyes J,Cordero C,Balaguer F,Castells A,Jover R,Andreu M,Syngal S,Boland CR,Llor X

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND & AIMS:Crohn's disease (CD) is an immunologically mediated inflammatory disease of the gastrointestinal tract. Due to a high morbidity and/or an increase in mortality in refractory cases, a new treatment approach is needed. In theory, maximum immune ablation by autologous hematopoietic stem cell transplantat...

journal_title：Gastroenterology

authors： Oyama Y,Craig RM,Traynor AE,Quigley K,Statkute L,Halverson A,Brush M,Verda L,Kowalska B,Krosnjar N,Kletzel M,Whitington PF,Burt RK

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND & AIMS:The mechanisms for tissue regeneration and renewal after acute pancreatitis are not well understood but may involve activation of Notch signaling. To study the effect of Notch signaling ablation during acute experimental pancreatitis, we used a chemical and genetic approach to ablate Notch signaling i...

journal_title：Gastroenterology

authors： Siveke JT,Lubeseder-Martellato C,Lee M,Mazur PK,Nakhai H,Radtke F,Schmid RM

更新日期：2008-02-01 00:00:00

abstract：:A patient is reported with eosinophilic enteritis of the jejunum with fatal evolution. Surgical resection was considered impossible and medical treatment with corticosteroids, elemental diet, parenteral nutrition, and antimicrobials to combat the intestinal bacterial overgrowth failed to control the disease. The destr...

journal_title：Gastroenterology

authors： Tytgat GN,Grijm R,Dekker W,Den Hartog NA

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Capsaicin-sensitive neurons contain various peptides including calcitonin gene-related peptide. This study examines (1) whether calcitonin gene-related peptide is involved in capsaicin-induced gastroprotection and (2) whether nitric oxide and prostaglandin are required for calcitonin gene-related peptide to ...

journal_title：Gastroenterology

authors： Lambrecht N,Burchert M,Respondek M,Müller KM,Peskar BM

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND & AIMS:The mechanism by which sulindac causes regression of adenomas in patients with familial adenomatous polyposis (FAP) is unclear. Conflicting data on the drug's effects on colorectal epithelial proliferation have been reported. An alternative mechanism, and one not previously studied, is via induction o...

journal_title：Gastroenterology

authors： Pasricha PJ,Bedi A,O'Connor K,Rashid A,Akhtar AJ,Zahurak ML,Piantadosi S,Hamilton SR,Giardiello FM

更新日期：1995-09-01 00:00:00