Corticosterone mediates reciprocal changes in CB 1 and TRPV1 receptors in primary sensory neurons in the chronically stressed rat.

abstract：:Antimitochondrial antibodies, serological hallmarks of primary biliary cirrhosis, recently were found to be directed against the E2 subunits of mitochondrial dehydrogenase complexes (pyruvate, branched-chain ketoacid, and alpha-ketoglutarate dehydrogenases). The objectives of this study were to extend these findings a...

journal_title：Gastroenterology

authors： Yoshida T,Bonkovsky H,Ansari A,Danner D

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND & AIMS:The Pediatric Crohn's Disease Activity Index (PCDAI) is a multi-item measure that, in contrast to the adult-derived CDAI, includes linear growth and places less emphasis on subjectively reported symptoms but more on laboratory parameters of intestinal inflammation. This study compared the feasibility,...

journal_title：Gastroenterology

authors： Otley A,Loonen H,Parekh N,Corey M,Sherman PM,Griffiths AM

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND & AIMS:Two percent to 4% of all cases of colorectal cancer (CRC) are associated with Lynch syndrome. Dominant clustering of CRC (non-Lynch syndrome) accounts for 1%-3% of the cases. Because carcinogenesis is accelerated in Lynch syndrome, an intensive colonoscopic surveillance program has been recommended si...

journal_title：Gastroenterology

authors： Vasen HF,Abdirahman M,Brohet R,Langers AM,Kleibeuker JH,van Kouwen M,Koornstra JJ,Boot H,Cats A,Dekker E,Sanduleanu S,Poley JW,Hardwick JC,de Vos Tot Nederveen Cappel WH,van der Meulen-de Jong AE,Tan TG,Jacobs MA,Mohame

更新日期：2010-06-01 00:00:00

abstract：:Endosonography was performed preoperatively in 33 patients with common bile duct carcinoma and in 43 patients with carcinoma of the common hepatic duct and its bifurcation. The results were correlated with the histology of resected specimens according to the new (1987) TNM (tumor, node, metastasis) classification. End...

journal_title：Gastroenterology

authors： Tio TL,Cheng J,Wijers OB,Sars PR,Tytgat GN

更新日期：1991-05-01 00:00:00

abstract：:The intestinal epithelium is a repetitive sheet of crypt and villus units with stem cells at the bottom of the crypts. During postnatal development, crypts multiply via fission, generating 2 daughter crypts from 1 parental crypt. In the adult intestine, crypt fission is observed at a low frequency. Using intravital mi...

journal_title：Gastroenterology

authors： Bruens L,Ellenbroek SIJ,van Rheenen J,Snippert HJ

更新日期：2017-09-01 00:00:00

abstract：:An enteroscopic method that uses a pediatric colonoscope provides an alternative approach to the diagnostic and management problems arising in the setting of a Roux-en-Y limb hepaticojejunostomy or biliary diversion. Three patients with Roux-en-Y limb reconstructions who experienced recurrent cholangitis, recurrent pa...

journal_title：Gastroenterology

authors： Gostout CJ,Bender CE

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND & AIMS:A common variant in the solute carrier family 39 member 6 gene (SLC39A6) has been associated with survival times of patients with esophageal squamous cell carcinoma (ESCC). We investigated the function of SLC39A6 and ways in which this variant affects tumor progression by studying ESCC samples and cel...

journal_title：Gastroenterology

authors： Cheng X,Wei L,Huang X,Zheng J,Shao M,Feng T,Li J,Han Y,Tan W,Tan W,Lin D,Wu C

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND & AIMS:Postprandial glycemia excursions increase after gastric bypass surgery; this effect is even greater among patients with recurrent hypoglycemia. These patients also have increased postprandial levels of insulin and glucagon-like peptide 1 (GLP-1). We performed a clinical trial to determine the role of ...

journal_title：Gastroenterology

authors： Salehi M,Gastaldelli A,D'Alessio DA

更新日期：2014-03-01 00:00:00

abstract：:We studied intestinal function and hepatic microsomal phase I monooxygenase function in healthy, free-living subjects, aged 19-91 yr. In subjects (n = 114) given a diet including 100 g/day of fat, fecal fat in a 72-h collection did not increase with advancing age. D-Xylose excretion (n = 54) following a 25-g oral load...

journal_title：Gastroenterology

authors： Arora S,Kassarjian Z,Krasinski SD,Croffey B,Kaplan MM,Russell RM

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND & AIMS:Gastroesophageal reflux typically occurs after meals. During dual gastric and esophageal pH monitoring, we observed that postprandial refluxate was often more acidic than the gastric contents. This study aimed to investigate this phenomenon. METHODS:Dual gastric and esophageal pH tracings were analyz...

journal_title：Gastroenterology

authors： Fletcher J,Wirz A,Young J,Vallance R,McColl KE

更新日期：2001-10-01 00:00:00

abstract：:We investigated a hormonal mechanism in a trypsin inhibitor-induced pancreatic hypersecretion in rats. Intraduodenal administration of a synthetic trypsin inhibitor, camostat, resulted in significant increases in plasma concentration of both secretin and cholecystokinin in a dose-related manner that paralleled a signi...

journal_title：Gastroenterology

authors： Watanabe S,Takeuchi T,Chey WY

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND & AIMS:The secretion and function of antral histamine are not known. The aims of this study were to characterize the mechanisms of histamine release from the gastric antrum of humans, dogs, and rats and to determine whether histamine can influence the secretion of somatostatin and gastrin. METHODS:Somatosta...

journal_title：Gastroenterology

authors： Vuyyuru L,Schubert ML,Harrington L,Arimura A,Makhlouf GM

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:The role of cytotoxicity mediated by peripheral blood mononuclear cells for colonic epithelial cells in inflammatory bowel disease (IBD) is still controversial. To clarify it, we studied major histocompatibility antigen (MHC)-restricted T cell-mediated cytotoxicity (CTL). METHODS:Cytotoxicity was measured b...

journal_title：Gastroenterology

authors： Okazaki K,Morita M,Nishimori I,Sano S,Toyonaga M,Nakazawa Y,Yamamoto Y,Yamamoto Y

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND & AIMS:Host genetic factors are likely to contribute to the variable course of hepatic fibrosis in response to chronic liver injury. Similarly, the fibrotic response differs among inbred mouse strains after challenge with CCl(4). Our aim was to identify unknown susceptibility loci for hepatic fibrosis in a c...

journal_title：Gastroenterology

authors： Hillebrandt S,Goos C,Matern S,Lammert F

更新日期：2002-12-01 00:00:00

abstract：:The clinical case is presented of a 16-yr-old patient with thoracoabdominal duplication that communicated with the main pancreatic duct and the right pleural cavity and resulted in pancreaticopleural fistula. Although abdominal duplications communicating with the pancreas have been described before, to our knowledge, ...

journal_title：Gastroenterology

authors： Fitzgibbons RJ Jr,Nugent FW,Ellis FH Jr,Braasch JW,Scholz FJ

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND & AIMS:No controlled trial has examined the clinical efficacy of antibiotics in small bowel bacterial overgrowth. METHODS:Ten patients with bacterial overgrowth-related diarrhea underwent the following five 7-day treatment periods: untreated (control period), then placebo, and subsequently, in random order ...

journal_title：Gastroenterology

authors： Attar A,Flourié B,Rambaud JC,Franchisseur C,Ruszniewski P,Bouhnik Y

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND & AIMS:Gastric histology is not well studied in patients with Crohn's disease. The aim of this study was to analyze the histological appearance of gastric mucosa in patients with Crohn's disease. METHODS:In a prospective study, biopsy specimens taken from the antrum and body of 75 patients with known Crohn'...

journal_title：Gastroenterology

authors： Oberhuber G,Püspök A,Oesterreicher C,Novacek G,Zauner C,Burghuber M,Vogelsang H,Pötzi R,Stolte M,Wrba F

更新日期：1997-03-01 00:00:00

abstract：:To determine the amount of lactose that could be tolerated in a meal, 59 lactase-deficient American Indians, ranging in age from 5 to 62, were given graded doses of lactose. The diagnosis of lactase deficiency had beeen documented previously by showing increased breath hydrogen after an oral lactose load (2 g per kg, ...

journal_title：Gastroenterology

authors： Newcomer AD,McGill DB,Thomas PJ,Hofmann AF

更新日期：1978-01-01 00:00:00

abstract：:The polypeptide core of mucin glycoprotein subunits resists cleavage by proteases. To determine if the carbohydrate side chains of these subunits protect the underlying polypeptide core from proteolytic cleavage, we compared the effect of pancreatic proteases on hog gastric mucin before and after cleavage of its carbo...

journal_title：Gastroenterology

authors： Variyam EP,Hoskins LC

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND & AIMS:Hereditary hemochromatosis is a common disorder of iron homeostasis characterized by increased dietary iron absorption and progressive iron accumulation, mainly in the liver. Most patients are homozygous for the C282Y mutation in the HFE gene. However, not all individuals carrying the hemochromatosis-...

journal_title：Gastroenterology

authors： Bensaid M,Fruchon S,Mazères C,Bahram S,Roth MP,Coppin H

更新日期：2004-05-01 00:00:00

abstract：:This study was performed to determine the relationship between net ion fluxes across the rat gastric mucosa and gastric mucosal damage after gastric ischemia and after intravenous administration of acetylsalicylic acid, and to determine the effect of cimetidine on these parameters. Gastric mucosal blood, albumin, and ...

journal_title：Gastroenterology

authors： Pipkin G,Price CA,Parsons ME

更新日期：1984-12-01 00:00:00

abstract：:In vitro studies have shown that some bile salts inhibit the growth of intestinal bacteria. We investigated the possibility that bile salts might have a similar action in vivo in the ileum by performing serial anaerobic cultures and bile salt analyses on postprandial ileal fluid obtained anaerobically via intestinal t...

journal_title：Gastroenterology

authors： Williams RC,Showalter R,Kern F Jr

更新日期：1975-08-01 00:00:00

abstract：:A 17-yr-old boy developed acute proctosigmoiditis after the institution of isotretinoin for the treatment of cystic acne vulgaris. Painless diarrhea, accompanied by mucus and eventually blood, began within days of commencing treatment and persisted while the drug was administered. At sigmoidoscopy patchy mucosal infla...

journal_title：Gastroenterology

authors： Martin P,Manley PN,Depew WT,Blakeman JM

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The mammalian intestinal epithelium self-renews rapidly and homeostasis is preserved via tightly controlled mechanisms. Long noncoding RNAs transcribed from ultraconserved regions (T-UCRs) control different cell functions, but little is known about their role in maintaining the integrity of the inte...

journal_title：Gastroenterology

authors： Xiao L,Wu J,Wang JY,Chung HK,Kalakonda S,Rao JN,Gorospe M,Wang JY

更新日期：2018-02-01 00:00:00

abstract：:One hundred Chinese patients who received induction cytotoxic therapy for malignant lymphoma were prospectively studied to determine the incidence, morbidity, mortality, and predisposing factors for reactivation of hepatitis B virus replication during cytotoxic therapy. In 18 (67%) hepatitis B surface antigen-positive...

journal_title：Gastroenterology

authors： Lok AS,Liang RH,Chiu EK,Wong KL,Chan TK,Todd D

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND & AIMS:Most colon cancers arise from polypoid adenomas, but how these benign lesions develop into malignant neoplasms is not understood. This study examined the migration of epithelial cells within human adenomatous polyps by determining the distribution of proliferating and apoptotic cells and immunoreactiv...

journal_title：Gastroenterology

authors： Moss SF,Liu TC,Petrotos A,Hsu TM,Gold LI,Holt PR

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND & AIMS:Congenital diarrheal disorders are rare inherited intestinal disorders characterized by intractable, sometimes life-threatening, diarrhea and nutrient malabsorption; some have been associated with mutations in diacylglycerol-acyltransferase 1 (DGAT1), which catalyzes formation of triacylglycerol from ...

journal_title：Gastroenterology

authors： van Rijn JM,Ardy RC,Kuloğlu Z,Härter B,van Haaften-Visser DY,van der Doef HPJ,van Hoesel M,Kansu A,van Vugt AHM,Thian M,Kokke FTM,Krolo A,Başaran MK,Kaya NG,Aksu AÜ,Dalgıç B,Ozcay F,Baris Z,Kain R,Stigter ECA,Lich

更新日期：2018-07-01 00:00:00

abstract：:The results of balloon dilatation of upper digestive tract stricture in 111 patients were evaluated. Eighty-eight patients had esophageal strictures and 23 had gastric or pyloric strictures. Thirty-six patients had strictures associated with previous operations. Twenty-two percent of the patients with esophageal stric...

journal_title：Gastroenterology

authors： Lindor KD,Ott BJ,Hughes RW Jr

更新日期：1985-09-01 00:00:00

abstract：:Helicobacter pylori infects the stomach of half of the human population worldwide and causes chronic active gastritis, which can lead to peptic ulcer disease, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. The host immune response to the infection is ineffective, because the bacterium persists...

journal_title：Gastroenterology

authors： Wilson KT,Crabtree JE

更新日期：2007-07-01 00:00:00

abstract：:Approximately 10% of persons 70 years old or older are now diagnosed with pancreatic cysts, but it is not clear which ones require additional analysis, interventions, or follow-up. Primary care doctors rely on gastroenterologists for direction because no one wants to miss a diagnosis of pancreatic cancer, but meanwhil...

journal_title：Gastroenterology

authors： Farrell JJ,Fernández-del Castillo C

更新日期：2013-06-01 00:00:00