当前位置： SCI文献检索 > GASTROENTEROLOGY期刊下所有文献 > Development of sustained achlorhydria in a patient with the Zollinger-Ellison syndrome treated with omeprazole.

Development of sustained achlorhydria in a patient with the Zollinger-Ellison syndrome treated with omeprazole.

Abstract：

:Spontaneous remission of gastric acid hypersecretion in the Zollinger-Ellison syndrome occurs rarely. This study shows the development of gastric secretory mucosal atrophy resulting in achlorhydria and loss of pepsin secretion in a 63-year-old woman with the Zollinger-Ellison syndrome. Reduced secretion began soon after starting treatment with omeprazole, and achlorhydria became complete 6 months later. The patient remains well with normal endoscopy results and is achlorhydric 4 years after the start of treatment and 34 months after stopping omeprazole. She was not colonized with Helicobacter pylori until 36 months after developing achlorhydria. Serum gastrin has increased from 1000 to between 5000 and 12,500 ng/L (pg/mL), was not suppressible by gastric acidification, and was not associated with G-cell hyperplasia. She also has a normal Schilling test and normal immunoglobulins, and lacks antibodies to parietal cells or H+, K(+)-ATPase. Moderate enterochromaffinlike cell hyperplasia is apparent for the first time on the latest biopsy sample.

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Griffith JL,Cummings OW,Hirschowitz BI

doi

10.1016/0016-5085(91)90484-3

subject

Has Abstract

pub_date

1991-07-01 00:00:00

pages

242-6

issue

1

eissn

0016-5085

issn

1528-0012

pii

0016-5085(91)90484-3

journal_volume

101

pub_type

杂志文章

相关文献

GASTROENTEROLOGY文献大全
  • Identification of EpCAM as the gene for congenital tufting enteropathy.

    abstract：BACKGROUND & AIMS:Congenital tufting enteropathy (CTE) is a rare autosomal recessive diarrheal disorder presenting in the neonatal period. CTE is characterized by intestinal epithelial cell dysplasia leading to severe malabsorption and significant morbidity and mortality. The pathogenesis and genetics of this disorder ...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/j.gastro.2008.05.036

    authors： Sivagnanam M,Mueller JL,Lee H,Chen Z,Nelson SF,Turner D,Zlotkin SH,Pencharz PB,Ngan BY,Libiger O,Schork NJ,Lavine JE,Taylor S,Newbury RO,Kolodner RD,Hoffman HM

    更新日期：2008-08-01 00:00:00

  • Influence of cigarette smoking on healing and relapse in duodenal ulcer disease.

    abstract：:There are conflicting reports on the influence of cigarette smoking on healing in patients with duodenal ulcer; some studies show an adverse effect on healing rate and others no effect. This study reports the influence of smoking on short-term healing and relapse rate in 135 patients with duodenal ulcer who were treat...

    journal_title：Gastroenterology

    pub_type： 临床试验,杂志文章

    doi：

    authors： Korman MG,Hansky J,Eaves ER,Schmidt GT

    更新日期：1983-10-01 00:00:00

  • Celiac sprue and Crohn's disease: an association causing severe growth retardation.

    abstract：:Celiac sprue and Crohn's disease have very rarely been documented in the same patient. We report a case involving an adolescent male with known Crohn's disease who had extreme wasting, growth retardation, intractable diarrhea, and delay in development of secondary sexual characteristics. Peroral jejunal biopsy showed ...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：

    authors： Euler AR,Ament ME

    更新日期：1977-04-01 00:00:00

  • Plasma arginine vasopressin response to oral, gastric, and intravenous water load in patients with cirrhosis.

    abstract：BACKGROUND/AIMS:Hepatic osmoreceptors are sensitive to changes in portal blood osmolality and cause variations in plasma antidiuretic hormone and water diuresis, which prevent major systemic osmotic changes. Insensitivity of hepatic osmoreceptors might contribute to maintaining increased plasma levels of antidiuretic h...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/0016-5085(94)90702-1

    authors： Castellano G,Solis-Herruzo JA,Gonzalez A,Morillas JD,Moreno D,Muñoz T,Larrodera L

    更新日期：1994-03-01 00:00:00

  • Frequency and significance of serum alpha-fetoprotein elevation in severe hepatitis B surface antigen-negative chronic active hepatitis.

    abstract：:To determine the frequency and significance of alpha-fetoprotein elevation in severe hepatitis B surface antigen-negative chronic active hepatitis, 558 serum samples obtained from 83 patients were tested by an immunoenzymometric assay. All patients received corticosteroids and sampling occurred at 6-12-mo intervals du...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/0016-5085(87)90429-x

    authors： Czaja AJ,Beaver SJ,Wood JR,Klee GG,Go VL

    更新日期：1987-10-01 00:00:00

  • Hepatic expression of CXC chemokines predicts portal hypertension and survival in patients with alcoholic hepatitis.

    abstract：BACKGROUND & AIMS:Alcoholic hepatitis (AH) is characterized by hepatocellular damage, inflammation, and fibrosis. We performed a prospective study to associate hepatic expression of the CXC subfamily of chemokines with histology findings and prognosis of patients with AH. METHODS:Liver biopsy samples from 105 patients...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/j.gastro.2009.01.056

    authors： Dominguez M,Miquel R,Colmenero J,Moreno M,García-Pagán JC,Bosch J,Arroyo V,Ginès P,Caballería J,Bataller R

    更新日期：2009-05-01 00:00:00

  • Increased muscle protein catabolism caused by carbon tetrachloride hepatic injury in rats.

    abstract：:This study was undertaken to determine the pathogenesis of muscle atrophy that frequently accompanies liver disease. Hepatic injury was induced in rats by giving weekly intragastric doses of carbon tetrachloride (CCl4) in combination with phenobarbital in the drinking water. Muscle protein catabolism was assessed duri...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/0016-5085(92)91733-k

    authors： Weber FL Jr,Macechko PT,Kelson SR,Karajiannis E,Hassan MO

    更新日期：1992-05-01 00:00:00

  • Acute relapsing pancreatitis as a complication of papillary stenosis after endoscopic sphincterotomy.

    abstract：:Endoscopic sphincterotomy has proven to be a safe alternative to surgery for selected types of biliary disease. Despite a relatively low morbidity, postprocedure complications are well described. This report presents an experience with three patients in whom acute relapsing pancreatitis developed as a possible complic...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/0016-5085(93)90663-w

    authors： Asbun HJ,Rossi RL,Heiss FW,Shea JA

    更新日期：1993-06-01 00:00:00

  • Choledochoduodenal flow: effect of the sphincter of Oddi in opossums and cats.

    abstract：:The aim of this study was to test in vivo (a) whether the sphincter of Oddi acts as a resistor or also as a pump, (b) the effect of an IV infusion of cholecystokinin (CCK) on choledochoduodenal flow, and (c) the ability of the choledochoduodenal junction to prevent duodenobiliary reflux in two animal species, opossums...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/0016-5085(90)90469-h

    authors： Calabuig R,Weems WA,Moody FG

    更新日期：1990-12-01 00:00:00

  • Sucrase-isomaltase is an adenosine 3',5'-cyclic monophosphate-dependent epithelial chloride channel.

    abstract：BACKGROUND & AIMS:We previously isolated a monoclonal antibody against a Necturus gallbladder epitope that blocks native adenosine 3',5'-cyclic monophosphate (cAMP)-dependent chloride channels in intestine, gallbladder, urinary bladder, and airway epithelia in various animals. METHODS:Using this antibody, we purified ...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/gast.2001.20884

    authors： Finn AL,Kuzhikandathil EV,Oxford GS,Itoh-Lindstrom Y

    更新日期：2001-01-01 00:00:00

  • Defective Fc receptor-mediated clearance in patients with primary biliary cirrhosis.

    abstract：:Fc receptor-mediated clearance of immunoglobulin G-coated autologous erythrocytes was studied in patients with primary biliary cirrhosis (n = 14), alcoholic liver cirrhosis (n = 5) and healthy reference individuals (n = 14). The mean half-life of the sensitized erythrocytes was significantly prolonged in patients with...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/0016-5085(91)90736-5

    authors： Ekdahl KN,Lööf L,Nyberg A,Nilsson UR,Nilsson B

    更新日期：1991-10-01 00:00:00

  • Somatostatin 28: effects on exocrine pancreatic secretion in conscious dogs.

    abstract：:The effect of somatostatin 28, a noval intestinal peptide containing somatostatin in its C-terminal portion, was tested on basal exocrine pancreatic secretion on conscious dogs and after stimulation by secretin (1 CU x kg-1 x hr-1), caerulein (37.5 ng x kg-1 x hr-1) or secretin (2 CU x kg-1 x hr-1) caerulein (37.5 ng ...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：

    authors： Susini C,Esteve JP,Vaysse N,Pradayrol L,Ribet A

    更新日期：1980-10-01 00:00:00

  • Epidemiology, Presentation, and Diagnosis of Celiac Disease.

    abstract：:The incidence of celiac disease is increasing, partly because of improved recognition of, and testing for, the disease. The rise in incidence is also due to a real increase of this immune-based disorder, independent of disease detection. The reasons for this true rise in recent decades are unknown but may be related t...

    journal_title：Gastroenterology

    pub_type： 杂志文章,评审

    doi：10.1053/j.gastro.2020.06.098

    authors： Lebwohl B,Rubio-Tapia A

    更新日期：2021-01-01 00:00:00

  • Enhanced production of endogenous prostaglandin in obstructive jaundiced pancreas in dogs.

    abstract：:Endogenous pancreatic prostaglandin production in control and obstructive jaundice was investigated using isolated and perfused dog pancreas. In both groups, spontaneous production of prostaglandin E2 and prostaglandin I2 was recorded, and the levels did not change in both groups. The production of both prostaglandins...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/0016-5085(90)90347-4

    authors： Kuroda T,Kajikawa S,Hanazaki K,Horigome N,Sodeyama H,Horiuchi A,Iwatsuki K,Chiba S,Homma T,Iida F

    更新日期：1990-05-01 00:00:00

  • Causes of Post-Colonoscopy Colorectal Cancers Based on World Endoscopy Organization System of Analysis.

    abstract：BACKGROUND & AIMS:Postcolonoscopy colorectal cancer (PCCRC) is CRC diagnosed after a colonoscopy in which no cancer was found. A consensus article from the World Endoscopy Organization (WEO) proposed an approach for investigating and categorizing PCCRCs detected within 4 years of a colonoscopy. We aimed to identify cas...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/j.gastro.2019.12.031

    authors： Anderson R,Burr NE,Valori R

    更新日期：2020-04-01 00:00:00

  • Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics.

    abstract：BACKGROUND & AIMS:In 1988, we reported the first twin study in inflammatory bowel disease. The aim of the current study was to follow up these twins regarding new cases of inflammatory bowel disease and Crohn's disease characteristics using the Vienna classification. METHODS:The official Swedish population register an...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/s0016-5085(03)00385-8

    authors： Halfvarson J,Bodin L,Tysk C,Lindberg E,Järnerot G

    更新日期：2003-06-01 00:00:00

  • Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.

    abstract：BACKGROUND & AIMS:Reactive oxidative species (ROS) are believed to be involved in the progression of nonalcoholic steatohepatitis (NASH). However, little is known about the sources of ROS in hepatocytes or their role in disease progression. We studied the effects of nicotinamide adenine dinucleotide phosphate reduced o...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/j.gastro.2015.04.009

    authors： Bettaieb A,Jiang JX,Sasaki Y,Chao TI,Kiss Z,Chen X,Tian J,Katsuyama M,Yabe-Nishimura C,Xi Y,Szyndralewiez C,Schröder K,Shah A,Brandes RP,Haj FG,Török NJ

    更新日期：2015-08-01 00:00:00

  • Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society.

    abstract：:Adenomatous polyps are the most common neoplastic findings discovered in people who undergo colorectal screening or who have a diagnostic work-up for symptoms. It was common practice in the 1970s for these patients to have annual follow-up surveillance examinations to detect additional new adenomas and missed synchron...

    journal_title：Gastroenterology

    pub_type： 杂志文章,实务指引,评审

    doi：10.1053/j.gastro.2006.03.012

    authors： Winawer SJ,Zauber AG,Fletcher RH,Stillman JS,O'Brien MJ,Levin B,Smith RA,Lieberman DA,Burt RW,Levin TR,Bond JH,Brooks D,Byers T,Hyman N,Kirk L,Thorson A,Simmang C,Johnson D,Rex DK,US Multi-Society Task Force on Colo

    更新日期：2006-05-01 00:00:00

  • Preliminary evaluation of safety and activity of recombinant human interleukin 11 in patients with active Crohn's disease.

    abstract：BACKGROUND & AIMS:Recombinant human interleukin 11 (rhIL-11) is a cytokine with thrombocytopoietic activity and anti-inflammatory and mucosal protective effects. The objectives of this study were to investigate the safety and tolerability of rhIL-11 in patients with Crohn's disease and to explore the effects of dose an...

    journal_title：Gastroenterology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0016-5085(99)70550-0

    authors： Sands BE,Bank S,Sninsky CA,Robinson M,Katz S,Singleton JW,Miner PB,Safdi MA,Galandiuk S,Hanauer SB,Varilek GW,Buchman AL,Rodgers VD,Salzberg B,Cai B,Loewy J,DeBruin MF,Rogge H,Shapiro M,Schwertschlag US

    更新日期：1999-07-01 00:00:00

  • Gastrin secretion from human antral G cells in culture.

    abstract：:Receptor-dependent and -independent regulation of gastrin secretion from cultured human antral G cells was investigated. Human antral mucosal cell preparations that were enriched for G cells were obtained by sequential incubations with collagenase and ethylenediaminetetraacetic acid, centrifugal elutriation, and short...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/0016-5085(90)91226-v

    authors： Campos RV,Buchan AM,Meloche RM,Pederson RA,Kwok YN,Coy DH

    更新日期：1990-07-01 00:00:00

  • Severe TNF receptor-associated periodic syndrome due to 2 TNFRSF1A mutations including a new F60V substitution.

    abstract：:Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is typically characterized by episodic fever, myalgia, skin rash, conjunctivitis, and abdominal cramps. Recently, mutations in the TNFRSF1A gene on chromosome 12p13 encoding tumor necrosis factor receptor type 1 have been linked to this autoinflammato...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/j.gastro.2005.09.014

    authors： Haas SL,Lohse P,Schmitt WH,Hildenbrand R,Karaorman M,Singer MV,Böcker U

    更新日期：2006-01-01 00:00:00

  • Real-Time Characterization of Diminutive Colorectal Polyp Histology Using Narrow-Band Imaging: Implications for the Resect and Discard Strategy.

    abstract：BACKGROUND & AIMS:Narrow-band imaging (NBI) allows real-time histologic classification of colorectal polyps. We investigated whether endoscopists without prior training in NBI can achieve the following thresholds recommended by the American Society for Gastrointestinal Endoscopy: for diminutive colorectal polyps charac...

    journal_title：Gastroenterology

    pub_type： 杂志文章,多中心研究

    doi：10.1053/j.gastro.2015.10.042

    authors： Patel SG,Schoenfeld P,Kim HM,Ward EK,Bansal A,Kim Y,Hosford L,Myers A,Foster S,Craft J,Shopinski S,Wilson RH,Ahnen DJ,Rastogi A,Wani S

    更新日期：2016-02-01 00:00:00

  • A novel secretin receptor splice variant potentially useful for early diagnosis of pancreatic carcinoma.

    abstract：BACKGROUND & AIMS:Pancreatic and bile duct carcinomas represent highly aggressive malignancies that evolve from secretin receptor-rich ductular cells. With premessenger RNA splicing abnormalities common in cancer, we evaluated whether an abnormal secretin receptor spliceoform were present, characterized it, and develop...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/j.gastro.2007.06.013

    authors： Hayes GM,Carrigan PE,Dong M,Reubi JC,Miller LJ

    更新日期：2007-09-01 00:00:00

  • The value of serologic markers in indeterminate colitis: a prospective follow-up study.

    abstract：BACKGROUND & AIMS:In the absence of pathognomonic markers for Crohn's disease (CD) and ulcerative colitis (UC), the diagnosis of inflammatory bowel disease depends on a compendium of clinical, radiographic, endoscopic, and histologic criteria that bears imperfect specificity to the individual disorders. In 10% of cases...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/gast.2002.32980

    authors： Joossens S,Reinisch W,Vermeire S,Sendid B,Poulain D,Peeters M,Geboes K,Bossuyt X,Vandewalle P,Oberhuber G,Vogelsang H,Rutgeerts P,Colombel JF

    更新日期：2002-05-01 00:00:00

  • Glycine-extended gastrin synergizes with gastrin 17 to stimulate acid secretion in gastrin-deficient mice.

    abstract：BACKGROUND & AIMS:Studies in gastrin-deficient mice have demonstrated critical roles for gastrin peptides in the regulation of gastric acid secretion, but the relative contributions of amidated (G-17) and glycine-extended (G17-Gly) gastrin remain unclear. We examined the effects of these 2 forms of gastrin on acid secr...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/gast.2000.16480

    authors： Chen D,Zhao CM,Dockray GJ,Varro A,Van Hoek A,Sinclair NF,Wang TC,Koh TJ

    更新日期：2000-09-01 00:00:00

  • Murine leptin deficiency alters Kupffer cell production of cytokines that regulate the innate immune system.

    abstract：BACKGROUND & AIMS:ob/ob mice are used to study the mechanisms that regulate the progression from steatosis to nonalcoholic steatohepatitis. The livers of ob/ob mice are depleted of CD4-positive natural killer cells, components of the innate immune system that induce anti-inflammatory cytokines. Although this may explai...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/gast.2002.35997

    authors： Li Z,Lin H,Yang S,Diehl AM

    更新日期：2002-10-01 00:00:00

  • Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracil–based chemotherapy.

    abstract：BACKGROUND & AIMS:Patients with colorectal tumors with microsatellite instability (MSI) have better prognoses than patients with tumors without MSI, but have a poor response to 5-fluorouracil–based chemotherapy. A dominant-negative form of heat shock protein (HSP)110 (HSP110DE9) expressed by cancer cells with MSI, via ...

    journal_title：Gastroenterology

    pub_type： 杂志文章,多中心研究

    doi：10.1053/j.gastro.2013.10.054

    authors： Collura A,Lagrange A,Svrcek M,Marisa L,Buhard O,Guilloux A,Wanherdrick K,Dorard C,Taieb A,Saget A,Loh M,Soong R,Zeps N,Platell C,Mews A,Iacopetta B,De Thonel A,Seigneuric R,Marcion G,Chapusot C,Lepage C,Bouvier

    更新日期：2014-02-01 00:00:00

  • Prevention of hepatitis B infection by hepatitis B immune globulin in infants born to mothers with acute hepatitis during pregnancy.

    abstract：:Eleven infants born to mothers with acute hepatitis B during the third trimester of pregnancy who were hepatitis B surface antigen-positive at delivery were treated with hepatitis B immune globulin within 24-48 h of birth. Five infants received one dose of hepatitis B immune globulin and 6 infants received a second do...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1016/0016-5085(85)90757-7

    authors： Tong MJ,Nair PV,Thursby M,Schweitzer IL

    更新日期：1985-07-01 00:00:00

  • Recombinant factor VIIa for upper gastrointestinal bleeding in patients with cirrhosis: a randomized, double-blind trial.

    abstract：BACKGROUND & AIMS:Upper gastrointestinal bleeding (UGIB) is a severe and frequent complication of cirrhosis. Recombinant coagulation factor VIIa (rFVIIa) has been shown to correct the prolonged prothrombin time in patients with cirrhosis and UGIB. This trial aimed to determine efficacy and safety of rFVIIa in cirrhotic...

    journal_title：Gastroenterology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1053/j.gastro.2004.07.015

    authors： Bosch J,Thabut D,Bendtsen F,D'Amico G,Albillos A,González Abraldes J,Fabricius S,Erhardtsen E,de Franchis R,European Study Group on rFVIIa in UGI Haemorrhage.

    更新日期：2004-10-01 00:00:00

  • DDIT4 Licenses Only Healthy Cells to Proliferate During Injury-induced Metaplasia.

    abstract：BACKGROUND AND AIMS:In stomach, metaplasia can arise from differentiated chief cells that become mitotic via paligenosis, a stepwise program. In paligenosis, mitosis initiation requires reactivation of the cellular energy hub mTORC1 after initial mTORC1 suppression by DNA damage induced transcript 4 (DDIT4 aka REDD1). ...

    journal_title：Gastroenterology

    pub_type： 杂志文章

    doi：10.1053/j.gastro.2020.09.016

    authors： Miao ZF,Sun JX,Adkins-Threats M,Pang MJ,Zhao JH,Wang X,Tang KW,Wang ZN,Mills JC

    更新日期：2021-01-01 00:00:00