Genetic analysis in the colonia strain of Physarum polycephalum: heterothallic strains that mate with and are partially isogenic to the colonia strain.

abstract：:When ultraviolet-irradiated bacteriophage T4 is assayed at plating temperatures ranging from 20 degrees to 40 degrees, its survival increases at the higher temperatures. This "thermal rescue" requires an intact WXY system but not the denV pyrimidine dimer excision system. Mutation rates decrease with increasing temper...

journal_title：Genetics

authors： Conkling MA,Drake JW

更新日期：1984-08-01 00:00:00

abstract：:The genotypes of three color mutants in goldfish: a depigmentation character of larval melanophores, albinism and a recessive-transparent character, were analyzed by crossing experiments. The depigmentation character in the common goldfish is controlled by two dominant multiple genes, Dp1 and Dp2, and only fish with d...

journal_title：Genetics

authors： Kajishima T

更新日期：1977-05-01 00:00:00

abstract：:Gastrulation is fundamental to the development of multicellular animals. Along with neurulation, gastrulation is one of the major processes of morphogenesis in which cells or whole tissues move from the surface of an embryo to its interior. Cell internalization mechanisms that have been discovered to date in Caenorhab...

journal_title：Genetics

authors： Goldstein B,Nance J

更新日期：2020-02-01 00:00:00

abstract：:Segregation distorter (SD) chromosomes are preferentially transmitted to offspring from heterozygous SD/SD(+) males owing to the induced dysfunction of the SD(+)-bearing sperm. This phenomenon involves at least two major loci: the Sd locus whose presence is necessary for distortion to occur and the Rsp locus which act...

journal_title：Genetics

authors： Brittnacher JG,Ganetzky B

更新日期：1983-04-01 00:00:00

abstract：:In random mating autopolyploid populations which have not reached equilibrium, two alleles may be interdependent as a result of the phenomenon of gametic recombination, i.e. the maintenance through successive gamete generations of an association of two alleles from the same gamete in a source reference generation. Any...

journal_title：Genetics

authors： Gallais A

更新日期：1974-03-01 00:00:00

abstract：:Natural populations of Daphnia magna have been found which are polymorphic for electrophoretic variants of supernatant malic dehydrogenase, esterase, and alkaline phosphatase. Using these enzyme variants as genetic markers it has been possible to demonstrate the absence of recombination during parthenogenetic reproduc...

journal_title：Genetics

authors： Hebert PD,Ward RD

更新日期：1972-08-01 00:00:00

abstract：:Mitotic interconversion of the mating-type locus (mat1) of the fission yeast Schizosaccharomyces pombe is initiated by a double-strand break at mat1. The mat2 and mat3 loci act as nonrandom donors of genetic information for mat1 switching such that switches occur primarily (or only) to the opposite mat1 allele. Locati...

journal_title：Genetics

authors： Klar AJ,Bonaduce MJ

更新日期：1991-12-01 00:00:00

abstract：:In the Brassicaceae, self-vs. nonself-recognition in self-incompatibility is controlled by sporophytic S-alleles. Haplotypes specifying both SRK (S-receptor kinase) and SLG (S-locus glycoprotein) are considered to play an important role in the recognition reactions. We compared the nucleotide sequences of SRK9(Bc) and...

journal_title：Genetics

authors： Hinata K,Watanabe M,Yamakawa S,Satta Y,Isogai A

更新日期：1995-07-01 00:00:00

abstract：:We demonstrate that recent data from human males are consistent with constant interference levels among chromosomes under the two-pathway model, whereas inappropriately fitting shape parameters of Gamma distributions to immunofluorescent interfoci distances observed on finite chromosomes generates false interpretation...

journal_title：Genetics

authors： Housworth EA,Stahl FW

更新日期：2009-09-01 00:00:00

abstract：:Four genes encoding the major egg yolk polypeptides of the Mediterranean fruit fly Ceratitis capitata, vitellogenins 1 and 2 (VG1 and VG2), were cloned, characterized and partially sequenced. The genes are located on the same region of chromosome 5 and are organized in pairs, each encoding the two polypeptides on oppo...

journal_title：Genetics

authors： Rina M,Savakis C

更新日期：1991-04-01 00:00:00

abstract：:Detecting and quantifying the differences in individual genomes (i.e., genotyping), plays a fundamental role in most modern bioinformatics pipelines. Many scientists now use reduced representation next-generation sequencing (NGS) approaches for genotyping. Genotyping diploid individuals using NGS is a well-studied fie...

journal_title：Genetics

authors： Gerard D,Ferrão LFV,Garcia AAF,Stephens M

更新日期：2018-11-01 00:00:00

abstract：:The X chromosome requires special treatment in the mapping of quantitative trait loci (QTL). However, most QTL mapping methods, and most computer programs for QTL mapping, have focused exclusively on autosomal loci. We describe a method for appropriate treatment of the X chromosome for QTL mapping in experimental cros...

journal_title：Genetics

authors： Broman KW,Sen S,Owens SE,Manichaikul A,Southard-Smith EM,Churchill GA

更新日期：2006-12-01 00:00:00

abstract：:This article focuses on conducting global testing for association between a binary trait and a set of rare variants (RVs), although its application can be much broader to other types of traits, common variants (CVs), and gene set or pathway analysis. We show that many of the existing tests have deteriorating performan...

journal_title：Genetics

authors： Pan W,Kim J,Zhang Y,Shen X,Wei P

更新日期：2014-08-01 00:00:00

abstract：:Estimating the fixation probability of a beneficial mutation has a rich history in theoretical population genetics. Typically, to attain mathematical tractability, we assume that generation times are fixed, while the number of offspring per individual is stochastic. However, fixation probabilities are extremely sensit...

journal_title：Genetics

authors： Hubbarde JE,Wild G,Wahl LM

更新日期：2007-07-01 00:00:00

abstract：:Cyclic guanosine monophosphate (cGMP) is a key secondary messenger used in signal transduction in various types of sensory neurons. The importance of cGMP in the ASE gustatory receptor neurons of the nematode Caenorhabditis elegans was deduced by the observation that multiple receptor-type guanylyl cyclases (rGCs), en...

journal_title：Genetics

authors： Smith HK,Luo L,O'Halloran D,Guo D,Huang XY,Samuel AD,Hobert O

更新日期：2013-08-01 00:00:00

abstract：:Heterozygotes for three long inversions on chromosome 1 were analyzed by serial reconstruction from electron micrographs. Measurements of loop lengths at different meiotic prophase substages revealed that the homologous synapsis of the inverted region was gradually replaced by nonhomologous synapsis as loops were elim...

journal_title：Genetics

authors： Bojko M

更新日期：1990-03-01 00:00:00

abstract：:TAHRE, the least abundant of the three retrotransposons forming telomeres in Drosophila melanogaster, has high sequence similarity to the gag gene and untranslated regions of HeT-A, the most abundant telomere-specific retrotransposon. Despite TAHRE's apparent evolutionary relationship to HeT-A, we find TAHRE Gag canno...

journal_title：Genetics

authors： Fuller AM,Cook EG,Kelley KJ,Pardue ML

更新日期：2010-03-01 00:00:00

abstract：:Temporally spaced genetic data allow for more accurate inference of population genetic parameters and hypothesis testing on the recent action of natural selection. In this work, we develop a novel likelihood-based method for jointly estimating selection coefficient and allele age from time series data of allele freque...

journal_title：Genetics

authors： He Z,Dai X,Beaumont M,Yu F

更新日期：2020-10-01 00:00:00

abstract：:The Genetics Society of America (GSA) Medal recognizes researchers who have made outstanding contributions to the field of genetics in the past 15 years. The 2019 GSA Medal is awarded to Bonnie L. Bassler of Princeton University and the Howard Hughes Medical Institute in recognition of her groundbreaking studies of ba...

journal_title：Genetics

authors： Bassler BL

更新日期：2020-06-01 00:00:00

abstract：:Genetic study of the reproductive barriers between related species plays an essential role in understanding the process of speciation. We developed a new method for mapping all possible factors causing deviations from expected Mendelian segregation ratios in F(2) progeny, which substantially contribute to reproductive...

journal_title：Genetics

authors： Harushima Y,Nakagahra M,Yano M,Sasaki T,Kurata N

更新日期：2001-10-01 00:00:00

abstract：:Hairpin-tail (T(hp)) is a new allele of brachyury on chromosome 17 (linkage group IX) of the mouse. The morphological effects in the heterozygote are on the notochord and the tail. The homozygous abnormal is unknown. T(hp) is unique in that the phenotype of the heterozygote seems to depend on the source of the T(hp) g...

journal_title：Genetics

authors： JOHNSON DR

更新日期：1974-04-01 00:00:00

abstract：:IS1 is one of the smallest transposable elements found in bacteria (768 bp). It contains eight overlapping open-reading-frames (ORFs) greater than 50 codons, designated insA to insG and insB'. To determine which of the ORFs actually code for proteins involved in transposition, we have introduced amber codons into each...

journal_title：Genetics

authors： Jakowec M,Prentki P,Chandler M,Galas DJ

更新日期：1988-09-01 00:00:00

abstract：:This study attempted to assay the zygotic contribution of X chromosome genes to the genetic control of embryonic morphogenesis in Drosophila melanogaster. A systematic screen for X-linked genes which affect the morphology of the embryo was undertaken, employing the phenotype of whole mount embryos as the major screeni...

journal_title：Genetics

authors： Eberl DF,Hilliker AJ

更新日期：1988-01-01 00:00:00

abstract：:Neurons and glia display remarkable morphological plasticity, and remodeling of glia may facilitate neuronal shape changes. The molecular basis and control of glial shape changes is not well understood. In response to environmental stress, the nematode Caenorhabditis elegans enters an alternative developmental state, ...

journal_title：Genetics

authors： Procko C,Lu Y,Shaham S

更新日期：2012-04-01 00:00:00

abstract：:Genetic screens in Drosophila melanogaster and other organisms have been pursued to filter the genome for genetic functions important for memory formation. Such screens have employed primarily chemical or transposon-mediated mutagenesis and have identified numerous mutants including classical memory mutants, dunce and...

journal_title：Genetics

authors： Walkinshaw E,Gai Y,Farkas C,Richter D,Nicholas E,Keleman K,Davis RL

更新日期：2015-04-01 00:00:00

abstract：:The walls of Aspergillus nidulans conidia contain a green pigment that protects the spores from damage by ultraviolet light. At least two genes, wA and yA, are required for pigment synthesis: yA mutants produce yellow spores, wA mutants produce white spores, and wA mutations are epistatic to yA mutations. We cloned wA...

journal_title：Genetics

authors： Mayorga ME,Timberlake WE

更新日期：1990-09-01 00:00:00

abstract：:Florida teosinte from Honduras and Guanajuato teosinte have most of their knobs internally located and a common inversion in the short arm of chromosome 8. Teosintes from northern Guatemala, Huixta and Monajil, have all their knobs terminally located and do not have any inversions. Therefore, Florida teosinte from Hon...

journal_title：Genetics

authors： Ting YC

更新日期：1976-08-01 00:00:00

abstract：:The mutation process at microsatellite loci typically occurs at high rates and with stepwise changes in allele sizes, features that may introduce bias when using classical measures of population differentiation based on allele identity (e.g., F(ST), Nei's Ds genetic distance). Allele size-based measures of differentia...

journal_title：Genetics

authors： Hardy OJ,Charbonnel N,Fréville H,Heuertz M

更新日期：2003-04-01 00:00:00

abstract：:We used ends-in gene targeting to generate knockout mutations of the nucleosome assembly protein 1 (Nap1) gene in Drosophila melanogaster. Three independent targeted null-knockout mutations were produced. No wild-type NAP1 protein could be detected in protein extracts. Homozygous Nap1(KO) knockout flies were either em...

journal_title：Genetics

authors： Lankenau S,Barnickel T,Marhold J,Lyko F,Mechler BM,Lankenau DH

更新日期：2003-02-01 00:00:00

abstract：:Extensive Monte Carlo simulations are conducted of spatial distributions of two-locus genotypes in large, continuous populations under isolation by distance models. The results show that substantial patches of double homozygotes are present in the spatial structures, even when loci are unlinked. The stochastic spread ...

journal_title：Genetics

authors： Epperson BK

更新日期：1995-05-01 00:00:00