Inheritance during parthenogenesis in Daphnia magna.

abstract：:A strain of Caenorhabditis elegans was constructed that permits selection of dominant or sex-linked mutations that transform XO animals (normally male) into fertile females, using a feminizing mutation, tra-2(e2046gf), which by itself does not sexually transform XO males. Twenty-three mutations were isolated after che...

journal_title：Genetics

authors： Hodgkin J,Albertson DG

更新日期：1995-10-01 00:00:00

abstract：:In Drosophila and other insects egg production is related to the nutrients available. Somehow the nutritional status of the environment is translated into hormonal signs that can be "read" by each individual egg chamber, influencing the decision to either develop into an egg or die. We have shown that BR-C is a contro...

journal_title：Genetics

authors： Terashima J,Bownes M

更新日期：2004-08-01 00:00:00

abstract：:In female mammalian cells, the inactive X chromosome is replicated late in S phase while the active X chromosome is replicated earlier. The replication times of the X chromosomes reflect a general trend in which late replication is associated with gene repression and earlier replication with transcriptional competence...

journal_title：Genetics

authors： Diaz-Perez S,Ouyang Y,Perez V,Cisneros R,Regelson M,Marahrens Y

更新日期：2005-10-01 00:00:00

abstract：:We have used mutational and revertant analysis to study the elements of the 54-nucleotide COX2 5'-untranslated leader involved in translation initiation in yeast mitochondria and in activation by the COX2 translational activator. Pet111p. We generated a collection of mutants with substitutions spanning the entire COX2...

journal_title：Genetics

authors： Dunstan HM,Green-Willms NS,Fox TD

更新日期：1997-09-01 00:00:00

abstract：:Arabidopsis seedlings repair UV-induced DNA damage via light-dependent and independent pathways. The mechanism of the "dark repair" pathway is still unknown. To determine the number of genes required for dark repair and to investigate the substrate-specificity of this process we isolated mutants with enhanced sensitiv...

journal_title：Genetics

authors： Jiang CZ,Yen CN,Cronin K,Mitchell D,Britt AB

更新日期：1997-11-01 00:00:00

abstract：:Methods for inference and interpretation of evolutionary quantitative genetic parameters, and for prediction of the response to selection, are best developed for traits with normal distributions. Many traits of evolutionary interest, including many life history and behavioral traits, have inherently nonnormal distribu...

journal_title：Genetics

authors： de Villemereuil P,Schielzeth H,Nakagawa S,Morrissey M

更新日期：2016-11-01 00:00:00

abstract：:We have examined the stability of the tandemly repeated genes that encode the ribosomal RNA in Coprinus cinereus. These genes are contained within two linked HindIII fragments in a 3.0-Mb chromosome. We monitored the size of these fragments in both mitotic and meiotic segregants using the contour-clamped homogeneous e...

journal_title：Genetics

authors： Pukkila PJ,Skrzynia C

更新日期：1993-02-01 00:00:00

abstract：:Mitochondria of Neurospora crassa contain a cyanide-resistant alternative respiratory pathway in addition to the cytochrome pathway. The alternative oxidase is present only when electron flow through the cytochrome chain is restricted. Both genomic and cDNA copies for the alternative oxidase gene have been isolated an...

journal_title：Genetics

authors： Li Q,Ritzel RG,McLean LL,McIntosh L,Ko T,Bertrand H,Nargang FE

更新日期：1996-01-01 00:00:00

abstract：:The Genetics Society of America (GSA) Medal recognizes researchers who have made outstanding contributions to the field of genetics in the past 15 years. The 2019 GSA Medal is awarded to Bonnie L. Bassler of Princeton University and the Howard Hughes Medical Institute in recognition of her groundbreaking studies of ba...

journal_title：Genetics

authors： Bassler BL

更新日期：2020-06-01 00:00:00

abstract：:One crossover point between a pair of homologous chromosomes in meiosis appears to interfere with occurrence of another in the neighborhood. It has been revealed that Drosophila and Neurospora, in spite of their large difference in the frequency of crossover points, show very similar plots of coincidence-a measure of ...

journal_title：Genetics

authors： Fujitani Y,Mori S,Kobayashi I

更新日期：2002-05-01 00:00:00

abstract：:We examined linkage relationships for RecBC-mediated recombination in lytic cycle crosses of lambda phages bearing two cohesive end sites (cos) oriented in the same direction. The relationships obtained imply that a given recombinant tends to be packaged from the cos site that is the nearer one to the right of the exc...

journal_title：Genetics

authors： Stahl FW,Kobayashi I,Thaler D,Stahl MM

更新日期：1986-06-01 00:00:00

abstract：:Hepatic glucocorticoid receptor binding activity was measured in A/J, C57BL/6J, their F1 reciprocal crosses and their F1 recombinant inbred (RI) lines. The glucocorticoid binding capacity was measured in Hepes buffer and Hepes buffer plus dithiothreitol (DTT). The A/J parental strain showed higher levels, and a greate...

journal_title：Genetics

authors： Liu SL,Erickson RP

更新日期：1986-07-01 00:00:00

abstract：:Translation of the chloroplast psbC mRNA in the unicellular eukaryotic alga Chlamydomonas reinhardtii is controlled by interactions between its 547-base 5' untranslated region and the products of the nuclear loci TBC1, TBC2, and possibly TBC3. In this study, a series of site-directed mutations in this region was gener...

journal_title：Genetics

authors： Zerges W,Auchincloss AH,Rochaix JD

更新日期：2003-03-01 00:00:00

abstract：:Whereas nonlinear relationships between genes are acknowledged, there exist only a few methods for estimating nonlinear gene coexpression networks or gene regulatory networks (GCNs/GRNs) with common deficiencies. These methods often consider only pairwise associations between genes, and are, therefore, poorly capable ...

journal_title：Genetics

authors： Kontio JAJ,Rinta-Aho MJ,Sillanpää MJ

更新日期：2020-07-01 00:00:00

abstract：:The contributions of direct and inverted repeats to deletion formation were studied by characterizing Ampr revertants of plasmids with a series of insertion mutations at a specific site in the pBR322 ampicillin resistance (amp) gene. The inserts at this site are palindromic, variable in length, and bracketed by 9- or ...

journal_title：Genetics

authors： Weston-Hafer K,Berg DE

更新日期：1989-04-01 00:00:00

abstract：:In meiosis, multiple different DNA sequence motifs help to position homologous recombination at hotspots in the genome. How do the seemingly disparate cis-acting regulatory modules each promote locally the activity of the basal recombination machinery? We defined molecular mechanisms of action for five different hotsp...

journal_title：Genetics

authors： Mukiza TO,Protacio RU,Davidson MK,Steiner WW,Wahls WP

更新日期：2019-11-01 00:00:00

abstract：:C. elegans spermatogenesis employs lysosome-related fibrous body-membranous organelles (FB-MOs) for transport of many cellular components. Previous work showed that spe-10 mutants contain FB-MOs that prematurely disassemble, resulting in defective transport of FB components into developing spermatids. Consequently, sp...

journal_title：Genetics

authors： Gleason EJ,Lindsey WC,Kroft TL,Singson AW,L'hernault SW

更新日期：2006-01-01 00:00:00

abstract：:The detection of adaptive evolution at the molecular level is of interest not only as an insight into the process of evolution but also because of its functional implications for genes of interest. Here, we present the first genomics approach to detecting positive selection operating on the Bos taurus lineage, an impo...

journal_title：Genetics

authors： Lynn DJ,Freeman AR,Murray C,Bradley DG

更新日期：2005-07-01 00:00:00

abstract：:Recessive lethan mutations in the 3A1 to 3C2 region of the X-chromosome of Drosophila melanogaster were detected in 113 of 33,544 sperm treated by feeding 5 mM methyl methanesulfonate in 1% sucrose for 22 hours. Seven of the 113 lethans were sterile, leaving 106 for analysis by complementation tests. With only one exc...

journal_title：Genetics

authors： Liu CP,Lim JK

更新日期：1975-04-01 00:00:00

abstract：:Regulatory DNA from the Drosophila gene engrailed causes silencing of a linked reporter gene (mini-white) in transgenic Drosophila. This silencing is strengthened in flies homozygous for the transgene and has been called "pairing-sensitive silencing." The pairing-sensitive silencing activities of a large fragment (2.6...

journal_title：Genetics

authors： Americo J,Whiteley M,Brown JL,Fujioka M,Jaynes JB,Kassis JA

更新日期：2002-04-01 00:00:00

abstract：:Under certain environmental conditions, naturally transforming bacteria are induced to pick up DNA released into the environment by other cells of the same or closely related species and, by homologous recombination, integrate that DNA into their chromosome. The selective pressures responsible for the evolution and ma...

journal_title：Genetics

authors： Mongold JA

更新日期：1992-12-01 00:00:00

abstract：:Though much has been learned about the process of ovarian follicle maturation through studies of oogenesis in both vertebrate and invertebrate systems, less is known about how follicles form initially. In Drosophila, two somatic follicle stem cells (FSCs) in each ovariole give rise to all polar cells, stalk cells, and...

journal_title：Genetics

authors： Nystul T,Spradling A

更新日期：2010-02-01 00:00:00

abstract：:The transcription factors Adr1 and Cat8 act in concert to regulate the expression of numerous yeast genes after the diauxic shift. Their activities are regulated by Snf1, the yeast homolog of the AMP-activated protein kinase of higher eukaryotes. Cat8 is regulated directly by Snf1, but how Snf1 regulates Adr1 is unkno...

journal_title：Genetics

authors： Ratnakumar S,Kacherovsky N,Arms E,Young ET

更新日期：2009-07-01 00:00:00

abstract：:Insulin-like growth factors (IGFs) control cell and organism growth through evolutionarily conserved signaling pathways. The mammalian acid-labile subunit (ALS) is a secreted protein that complexes with IGFs to modulate their activity. Recent work has shown that a Drosophila homolog of ALS, dALS, can also complex with...

journal_title：Genetics

authors： Swanson LE,Yu M,Nelson KS,Laprise P,Tepass U,Beitel GJ

更新日期：2009-04-01 00:00:00

abstract：:Retrotransposons are mobile genetic elements that colonize eukaryotic genomes by replicating through an RNA intermediate. As retrotransposons can move within the host genome, defense mechanisms have evolved to repress their potential mutagenic activities. In the fission yeast Schizosaccharomyces pombe, the mRNA of Tf2...

journal_title：Genetics

authors： Mallet PL,Larochelle M,Bachand F

更新日期：2017-02-01 00:00:00

abstract：:We have examined the effects of prolonged histidine deprivation on the reversion of Salmonella typhimurium histidine auxotrophs containing either hisG46, a missense mutation (CTC----CCC), or hisG428, an ochre mutation (CAA----TAA). Both of these mutants can revert to His+ via intragenic and extragenic mechanisms. Wher...

journal_title：Genetics

authors： Prival MJ,Cebula TA

更新日期：1992-10-01 00:00:00

abstract：:Mutations in the genealogy of the sequences in a random sample from a population can be classified as external and internal. External mutations are mutations that occurred in the external branches and internal mutations are mutations that occurred in the internal branches of the genealogy. Under the assumption of sele...

journal_title：Genetics

authors： Fu YX,Li WH

更新日期：1993-03-01 00:00:00

abstract：:Two strains of Drosophila melanogaster derived from different geographical localities were subjected to selection for fast and slow developmental rate. Four enzyme polymorphisms were monitored for their response to such selection. Significant changes in allele frequencies were effected for the alphaGpdh and 6Pgd polym...

journal_title：Genetics

authors： Cavener DR

更新日期：1983-09-01 00:00:00

abstract：:Deficiencies encompassing part or all of the X heterochromatin of Drosophila melanogaster have been linked to three abnormalities in male meiosis and spermatogenesis: X-Y nondisjunction, skewed sperm recovery ratios favoring sperm with reduced chromatin content, and sterility in males carrying either a Y-autosome tran...

journal_title：Genetics

authors： McKee B,Lindsley DL

更新日期：1987-07-01 00:00:00

abstract：:A spontaneously arising nuclear mutation, ss-1, has been identified in Chlamydomonas reinhardtii that decreases both streptomycin and spectinomycin resistance levels about 10-fold after its introduction into all wild-type, streptomycin-resistant and spectinomycin-resistant strains examined. The mutations for resistanc...

journal_title：Genetics

authors： Lee RW,Sapp JA

更新日期：1978-04-01 00:00:00