Synaptic adjustment of inversion loops in Neurospora crassa.

Abstract:

:Heterozygotes for three long inversions on chromosome 1 were analyzed by serial reconstruction from electron micrographs. Measurements of loop lengths at different meiotic prophase substages revealed that the homologous synapsis of the inverted region was gradually replaced by nonhomologous synapsis as loops were eliminated during pachytene. This synaptic adjustment was apparently not affected by crossovers which occurred within the 150- and 160-cM long loops.

journal_name

Genetics

journal_title

Genetics

authors

Bojko M

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

593-8

issue

3

eissn

0016-6731

issn

1943-2631

journal_volume

124

pub_type

杂志文章

相关文献

GENETICS文献大全
  • Using allele frequencies and geographic subdivision to reconstruct gene trees within a species: molecular variance parsimony.

    abstract::We formalize the use of allele frequency and geographic information for the construction of gene trees at the intraspecific level and extend the concept of evolutionary parsimony to molecular variance parsimony. The central principle is to consider a particular gene tree as a variable to be optimized in the estimation...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Excoffier L,Smouse PE

    更新日期:1994-01-01 00:00:00

  • Establishment of Locally Adapted Mutations Under Divergent Selection.

    abstract::We study the establishment probabilities of locally adapted mutations using a multi-type branching process framework. We find a surprisingly simple and intuitive analytical approximation for the establishment probabilities in a symmetric two-deme model under the assumption of weak (positive) selection. This is the fir...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.118.301104

    authors: Tomasini M,Peischl S

    更新日期:2018-07-01 00:00:00

  • Drosophila-host genetic control of susceptibility to Drosophila C virus.

    abstract::Interactions between Drosophila C virus (DCV) and its natural host, Drosophila melanogaster, were investigated using 15 geographical population samples infected by intraabdominal inoculation. These strains derived from natural populations of D. melanogaster differed in susceptibility to the DCVc. One strain was "parti...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Thomas-Orillard M,Jeune B,Cusset G

    更新日期:1995-08-01 00:00:00

  • Eukaryotic beta-alanine synthases are functionally related but have a high degree of structural diversity.

    abstract::beta-Alanine synthase (EC 3.5.1.6), which catalyzes the final step of pyrimidine catabolism, has only been characterized in mammals. A Saccharomyces kluyveri pyd3 mutant that is unable to grow on N-carbamyl-beta-alanine as the sole nitrogen source and exhibits diminished beta-alanine synthase activity was used to clon...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Gojković Z,Sandrini MP,Piskur J

    更新日期:2001-07-01 00:00:00

  • A Tn10-lacZ-kanR-URA3 gene fusion transposon for insertion mutagenesis and fusion analysis of yeast and bacterial genes.

    abstract::We describe here a new variant of transposon Tn10 especially adapted for transposon analysis of cloned yeast genes; it can equally well be used for analysis of prokaryotic genes. We have applied this element to analysis of the LEU2, RAD50, and CDC48 genes of Saccharomyces cerevisiae. This transposon, nicknamed mini-Tn...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Huisman O,Raymond W,Froehlich KU,Errada P,Kleckner N,Botstein D,Hoyt MA

    更新日期:1987-06-01 00:00:00

  • Inferring admixture histories of human populations using linkage disequilibrium.

    abstract::Long-range migrations and the resulting admixtures between populations have been important forces shaping human genetic diversity. Most existing methods for detecting and reconstructing historical admixture events are based on allele frequency divergences or patterns of ancestry segments in chromosomes of admixed indi...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.112.147330

    authors: Loh PR,Lipson M,Patterson N,Moorjani P,Pickrell JK,Reich D,Berger B

    更新日期:2013-04-01 00:00:00

  • An analysis of frequencies of chromosome configurations in wheat and wheat hybrids.

    abstract::Presynaptic association of homologous chromosomes is a prerequisite to the sequence of events that lead to chiasma formation. This association of homologous chromosomes, as entire units, occurs with probability a, and chiasma formation occurs independently in opposite chromosome arms with probability c. a and c have b...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Driscoll CJ,Bielig LM,Darvey NL

    更新日期:1979-04-01 00:00:00

  • Chromosomal patterns of microsatellite variability contrast sharply in African and non-African populations of Drosophila melanogaster.

    abstract::Levels of neutral variation are influenced by background selection and hitchhiking. The relative contribution of these evolutionary forces to the distribution of neutral variation is still the subject of ongoing debates. Using 133 microsatellites, we determined levels of variability on X chromosomes and autosomes in A...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Kauer M,Zangerl B,Dieringer D,Schlötterer C

    更新日期:2002-01-01 00:00:00

  • Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination.

    abstract::Loss or gain of whole chromosomes, or parts of chromosomes, is found in various pathological conditions, such as cancer and aneuploidy, and results from the missegregation of chromosomes during cellular division or abnormal mitotic recombination. We introduce a novel strategy for determining the consequences of segmen...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.108.092312

    authors: Duchon A,Besson V,Pereira PL,Magnol L,Hérault Y

    更新日期:2008-09-01 00:00:00

  • Genepool variation in genus Glycine subgenus Soja revealed by polymorphic nuclear and chloroplast microsatellites.

    abstract::A combination of nuclear and chloroplast simple sequence repeats (SSRs) have been used to investigate the levels and pattern of variability detected in Glycine max and G. soja genotypes. Based on the analysis of 700 soybean genotypes with 115 restriction fragment length polymorphism (RFLP) probes, 12 accessions were i...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Powell W,Morgante M,Doyle JJ,McNicol JW,Tingey SV,Rafalski AJ

    更新日期:1996-10-01 00:00:00

  • Selective sweep at the Drosophila melanogaster Suppressor of Hairless locus and its association with the In(2L)t inversion polymorphism.

    abstract::The hitchhiking model of population genetics predicts that an allele favored by Darwinian selection can replace haplotypes from the same locus previously established at a neutral mutation-drift equilibrium. This process, known as "selective sweep," was studied by comparing molecular variation between the polymorphic I...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Depaulis F,Brazier L,Veuille M

    更新日期:1999-07-01 00:00:00

  • Quantitative trait loci for grain yield and adaptation of durum wheat (Triticum durum Desf.) across a wide range of water availability.

    abstract::Grain yield is a major goal for the improvement of durum wheat, particularly in drought-prone areas. In this study, the genetic basis of grain yield (GY), heading date (HD), and plant height (PH) was investigated in a durum wheat population of 249 recombinant inbred lines evaluated in 16 environments (10 rainfed and 6...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.107.077297

    authors: Maccaferri M,Sanguineti MC,Corneti S,Ortega JL,Salem MB,Bort J,DeAmbrogio E,del Moral LF,Demontis A,El-Ahmed A,Maalouf F,Machlab H,Martos V,Moragues M,Motawaj J,Nachit M,Nserallah N,Ouabbou H,Royo C,Slama A,Tubero

    更新日期:2008-01-01 00:00:00

  • Genetic analysis of functional domains within the Drosophila LARK RNA-binding protein.

    abstract::LARK is an essential Drosophila RNA-binding protein of the RNA recognition motif (RRM) class that functions during embryonic development and for the circadian regulation of adult eclosion. LARK protein contains three consensus RNA-binding domains: two RRM domains and a retroviral-type zinc finger (RTZF). To show that ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: McNeil GP,Schroeder AJ,Roberts MA,Jackson FR

    更新日期:2001-09-01 00:00:00

  • OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes.

    abstract::OrthoList, a compendium of Caenorhabditis elegans genes with human orthologs compiled in 2011 by a meta-analysis of four orthology-prediction methods, has been a popular tool for identifying conserved genes for research into biological and disease mechanisms. However, the efficacy of orthology prediction depends on th...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.118.301307

    authors: Kim W,Underwood RS,Greenwald I,Shaye DD

    更新日期:2018-10-01 00:00:00

  • Multiple meiotic drive systems in the Drosophila melanogaster male.

    abstract::The behaviour of two "meiotic drive" systems, Segregation-Distorter (SD) and the sex chromosome sc(4)sc(8) has been examined in the same meiocyte. It has been found that the two systems interact in a specific way. When the distorting effects of SD and sc(4)sc(8) are against each other, there is no detectable interacti...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Miklos GL,Yanders AF,Peacock WJ

    更新日期:1972-09-01 00:00:00

  • A study of linkage disequilibrium in populations of Drosophila melanogaster.

    abstract::This paper presents the results of a study of linkage disequilibrium between five polymorphic enzyme genes located on chromosome 3 of D. melanogaster. Three sets of chromosomes were examined: two represented samples from successive years of the same natural population, and one came from a large laboratory population. ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Charlesworth B,Charlesworth D

    更新日期:1973-02-01 00:00:00

  • Cloning and sequencing the first HLA gene.

    abstract::This Perspectives article recounts the isolation and sequencing of the first human histocompatibility gene (HLA) in 1980-1981. At the time, general knowledge of the molecules of the immune system was already fairly extensive, and gene rearrangements in the immunoglobulin complex (discovered in 1976) had generated much...

    journal_title:Genetics

    pub_type: 杂志文章,评审

    doi:10.1534/genetics.110.113852

    authors: Jordan BR

    更新日期:2010-04-01 00:00:00

  • Experimental population genetics of meiotic drive systems. I. Pseudo-Y chromosomal drive as a means of eliminating cage populations of Drosophila melanogaster.

    abstract::The experimental population genetics of Y-chromosome drive in Drosophila melanogaster is approximated by studying the behavior of T(Y;2),SD lines. These exhibit "pseudo-Y" drive through the effective coupling of the Y chromosome to the second chromosome meiotic drive locus, Segregation distorter (SD). T(Y;2),SD males ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Lyttle TW

    更新日期:1977-06-01 00:00:00

  • Evolution and extinction of transposable elements in Mendelian populations.

    abstract::A model of the evolution of a transposable element family in a Mendelian host population is proposed that incorporates heritable phenotypic mutations in the elements. The temporal behavior of the numbers of mutant and wild-type elements is studied, and the expected extinction time of the transposable element family is...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Kaplan N,Darden T,Langley CH

    更新日期:1985-02-01 00:00:00

  • Inheritance and mapping of Compact (Cmpt), a new mutation causing hypermuscularity in mice.

    abstract::During selection for protein content in mice at the Technical University of Berlin, individuals showing high protein content and a compact exterior were noted. Animals showing this "Compact" phenotype were separated to form a new line. The present investigations were carried out on a Hungarian subpopulation of this li...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Varga L,Szabó G,Darvasi A,Müller G,Sass M,Soller M

    更新日期:1997-10-01 00:00:00

  • Paramutation in Drosophila Requires Both Nuclear and Cytoplasmic Actors of the piRNA Pathway and Induces Cis-spreading of piRNA Production.

    abstract::Transposable element activity is repressed in the germline in animals by PIWI-interacting RNAs (piRNAs), a class of small RNAs produced by genomic loci mostly composed of TE sequences. The mechanism of induction of piRNA production by these loci is still enigmatic. We have shown that, in Drosophila melanogaster, a clu...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.115.180307

    authors: Hermant C,Boivin A,Teysset L,Delmarre V,Asif-Laidin A,van den Beek M,Antoniewski C,Ronsseray S

    更新日期:2015-12-01 00:00:00

  • Improved Use of Small Reference Panels for Conditional and Joint Analysis with GWAS Summary Statistics.

    abstract::Due to issues of practicality and confidentiality of genomic data sharing on a large scale, typically only meta- or mega-analyzed genome-wide association study (GWAS) summary data, not individual-level data, are publicly available. Reanalyses of such GWAS summary data for a wide range of applications have become more ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.118.300813

    authors: Deng Y,Pan W

    更新日期:2018-06-01 00:00:00

  • Revisiting purine-histidine cross-pathway regulation in Saccharomyces cerevisiae: a central role for a small molecule.

    abstract::Because some metabolic intermediates are involved in more than one pathway, crosstalk between pathways is crucial to maintaining homeostasis. AMP and histidine biosynthesis pathways are coregulated at the transcriptional level in response to adenine availability. 5'-Phosphoribosyl-4-carboxamide-5-aminoimidazole (AICAR...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.104.039396

    authors: Rébora K,Laloo B,Daignan-Fornier B

    更新日期:2005-05-01 00:00:00

  • Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage.

    abstract::Genome stability in fission yeast requires the conserved S-phase kinase Hsk1 (Cdc7) and its partner Dfp1 (Dbf4). In addition to their established function in the initiation of DNA replication, we show that these proteins are important in maintaining genome integrity later in S phase and G2. hsk1 cells suffer increased...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.109.112284

    authors: Dolan WP,Le AH,Schmidt H,Yuan JP,Green M,Forsburg SL

    更新日期:2010-05-01 00:00:00

  • Comparative analysis of position-effect variegation mutations in Drosophila melanogaster delineates the targets of modifiers.

    abstract::In Drosophila melanogaster, heterochromatin-induced silencing or position-effect variegation (PEV) of a reporter gene has provided insights into the properties of heterochromatin. Class I modifiers suppress PEV, and class II modifiers enhance PEV when the modifier gene is present in fewer than two doses. We have exami...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Sass GL,Henikoff S

    更新日期:1998-02-01 00:00:00

  • Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins.

    abstract::Enhancer of split [E(spl)] is one of the neurogenic loci of Drosophila and, as such, is required for normal segregation of neural and epidermal cell progenitors. Genetic observations indicate that the E(spl) locus is in fact a gene complex comprising a cluster of related genes and that other genes of the region are al...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Knust E,Schrons H,Grawe F,Campos-Ortega JA

    更新日期:1992-10-01 00:00:00

  • Inferring coancestry in population samples in the presence of linkage disequilibrium.

    abstract::In both pedigree linkage studies and in population-based association studies there has been much interest in the use of modern dense genetic marker data to infer segments of gene identity by descent (ibd) among individuals not known to be related, to increase power and resolution in localizing genes affecting complex ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.111.137570

    authors: Brown MD,Glazner CG,Zheng C,Thompson EA

    更新日期:2012-04-01 00:00:00

  • Mapping of hybrid incompatibility loci in Nasonia.

    abstract::According to theory, F(2) hybrid breakdown (lethality or sterility) is due to incompatibilities between interacting genes of the different species (i.e., the breaking up of coadapted gene complexes). Detection of such incompatibilities is particularly straightforward in haplodiploid species, because virgin F(1) hybrid...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Gadau J,Page RE Jr,Werren JH

    更新日期:1999-12-01 00:00:00

  • On the interpretation of mutagenically induced mosaicism in Drosophila.

    abstract::This paper draws attention to the formal parallelism that exists between chromosomal-loss mosaicism and mutagenically induced mosaicism in Drosophila and suggests that, although the underlying processes by which these two types of genetic mosaics are generated are very different, the more refined methodology employed ...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:

    authors: Nissani M

    更新日期:1977-08-01 00:00:00

  • Lethal mutagenesis in viruses and bacteria.

    abstract::In this work we study how mutations that change physical properties of cell proteins (stability) affect population survival and growth. We present a model in which the genotype is presented as a set folding free energies of cell proteins. Mutations occur upon replication, so stabilities of some proteins in daughter ce...

    journal_title:Genetics

    pub_type: 杂志文章

    doi:10.1534/genetics.109.106492

    authors: Chen P,Shakhnovich EI

    更新日期:2009-10-01 00:00:00