Abstract：
:Levels of neutral variation are influenced by background selection and hitchhiking. The relative contribution of these evolutionary forces to the distribution of neutral variation is still the subject of ongoing debates. Using 133 microsatellites, we determined levels of variability on X chromosomes and autosomes in African and non-African D. melanogaster populations. In the ancestral African populations microsatellite variability was higher on X chromosomes than on autosomes. In non-African populations X-linked polymorphism is significantly more reduced than autosomal variation. In non-African populations we observed a significant positive correlation between X chromosomal polymorphism and recombination rate. These results are consistent with the interpretation that background selection shapes levels of neutral variability in the ancestral populations, while the pattern in derived populations is determined by multiple selective sweeps during the colonization process. Further research, however, is required to investigate the influence of inversion polymorphisms and unequal sex ratios.
journal_name
Geneticsjournal_title
Geneticsauthors
Kauer M,Zangerl B,Dieringer D,Schlötterer Ckeywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
247-56issue
1eissn
0016-6731issn
1943-2631journal_volume
160pub_type
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