Hypertrophy of neurons in the inferior olive after cerebellar ablations in the cat.

abstract：:By in situ hybridization, we show the ability of human neuroblastoma SY 5Y cells to synthesize apolipoprotein E (apoE) mRNA. This synthesis varied during cell NGF-differentiation: the mRNA level decreased during the first 4 days of NGF treatment (NGF 4 days) and then increased during the 3 following days (NGF 7 days)....

journal_title：Neuroscience letters

authors： Soulié C,Mitchell V,Dupont-Wallois L,Chartier-Harlin MC,Beauvillain JC,Delacourte A,Caillet-Boudin ML

更新日期：1999-04-16 00:00:00

abstract：:The 22Na+ efflux stimulated by selected agonists of the 4 excitatory amino acid receptors, previously detected in the striatum, has been studied on 22Na+-preloaded slices prepared from 10 major areas of the rat brain. All brain areas were found to be sensitive, albeit to varying extents, to excitatory amino acids. The...

journal_title：Neuroscience letters

authors： Luini A,Goldberg O,Teichberg VI

更新日期：1983-11-11 00:00:00

abstract：:In micturition control, the roles of ionotropic glutamate (iGlu) receptors NMDA and AMPA are well established, whereas little is known about the function of metabotropic glutamate (mGlu) receptors. Since antagonists for mGlu5 receptors are efficacious in animal models of inflammatory and neuropathic pain, we examined ...

journal_title：Neuroscience letters

authors： Hu Y,Dong L,Sun B,Guillon MA,Burbach LR,Nunn PA,Liu X,Vilenski O,Ford AP,Zhong Y,Rong W

更新日期：2009-01-23 00:00:00

abstract：:Post-mortem brain tissue from 15 patients dying with a diagnosis of senile dementia of Alzheimer type (SDAT) was compared with tissue obtained from 16 control patients at routine post-mortem. A significant fall in choline acetyltransferase (ChAT) activity was observed in the cortex, hippocampus and amygdala of the SDA...

journal_title：Neuroscience letters

authors： Rossor MN,Emson PC,Mountjoy CQ,Roth M,Iversen LL

更新日期：1980-12-01 00:00:00

abstract：:In this study, we examined the involvement of chemokine monocyte chemoattractant protein-1 (MCP-1) in the spinal cord of a rat model of cancer-induced bone pain (CIBP). In this model, CIBP was established by an intramedullary injection of Walker 256 cells into the tibia of rats. We observed a significant increase in e...

journal_title：Neuroscience letters

authors： Hu JH,Zheng XY,Yang JP,Wang LN,Ji FH

更新日期：2012-05-23 00:00:00

abstract：:A critical component of the cellular stress response, the p53 tumor suppressor protein must be functional for many cancer therapies to be effective. Adjuvant therapies that augment p53 function are predicted to sensitize tumor cells to cancer therapies that rely upon p53 for their efficacy. Of those strategies current...

journal_title：Neuroscience letters

authors： Ghassemifar S,Mendrysa SM

更新日期：2012-03-28 00:00:00

abstract：:Using inside-out configuration of patch clamp techniques, actin cytoskeleton modulation of large conductance calcium-activated potassium (BK(Ca)) channels was studied in hippocampal CA1 pyramidal neurons from adult rat. Disruption of actin filament after brief treatment with cytochalasin D (CD) markedly decreased acti...

journal_title：Neuroscience letters

authors： Huang H,Rao Y,Sun P,Gong LW

更新日期：2002-10-31 00:00:00

abstract：:In the rat, electrical stimulation of the cranial end of the cut hepatic branch of the vagus nerve modulated gastric contractions. When the gastric contraction rate reached approximately one per min, nerve stimulation caused total suppression. When the stomach was free of contraction, nerve stimulation initiated one. ...

journal_title：Neuroscience letters

authors： Lee KC

更新日期：1985-01-07 00:00:00

abstract：:Stem cells are used to generate differentiated somatic cells including neuronal cells. Synthesis and release of acetylcholine, a neurotransmitter and widely expressed signaling molecule, were investigated in the murine embryonic stem cell line CGR8 during early differentiation, i.e. in the presence of leukemia inhibit...

journal_title：Neuroscience letters

authors： Wessler I,Michel-Schmidt R,Schmidt H,Kaltwasser S,Unger R,Kirkpatrick CJ

更新日期：2013-06-28 00:00:00

abstract：:Unusual reactions to auditory stimuli are often observed in autism and may relate to ineffective inhibitory modulation of sensory input (sensory gating). A previous study of P50 sensory gating did not reveal abnormalities in high-functioning school age children [C. Kemner, B. Oranje, M.N. Verbaten, H. van Engeland, No...

journal_title：Neuroscience letters

authors： Orekhova EV,Stroganova TA,Prokofyev AO,Nygren G,Gillberg C,Elam M

更新日期：2008-03-28 00:00:00

abstract：:Changes in contingent negative variation (CNV), a brain-evoked potential related in arousal, as well as in serum triiodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH), prolactin (PRL), cortisol and growth hormone (GH) levels were recorded in 12 male volunteers receiving either thyrotropin-releasing ...

journal_title：Neuroscience letters

authors： Strollo F,Amabile G,Fattapposta F,Strollo G,More M,Riondino G

更新日期：1988-11-11 00:00:00

abstract：:Kynurenic acid (KYNA) is an antagonist of (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptors and it blocks the glycine site of the NMDA receptor preferentially (IC50 = 7.9 microM). KYNA is produced endogenously by transamination of its precursor L-kynurenin...

journal_title：Neuroscience letters

authors： Scharfman HE,Hodgkins PS,Lee SC,Schwarcz R

更新日期：1999-10-22 00:00:00

abstract：:We investigated whether the presence of unimodal or bimodal (synchronous) distractors would affect temporal order judgments (TOJs) for pairs of asynchronous audiovisual target stimuli. Participants made unspeeded TOJs regarding which of a pair of auditory and visual stimuli, presented at different stimulus onset async...

journal_title：Neuroscience letters

authors： Vatakis A,Spence C

更新日期：2006-11-06 00:00:00

abstract：:Using reverse transcription in combination with the polymerase chain reaction, the developmental expression of neurotrophins in organotypic slice cultures of rat hippocampus was investigated. Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) mRNA levels after different time periods in vitro were c...

journal_title：Neuroscience letters

authors： Förster E,Otten U,Frotscher M

更新日期：1993-06-11 00:00:00

abstract：:Intolerance of uncertainty (IU), or the increased affective response to situations with uncertain outcomes, is an important component process of anxiety disorders. Increased IU is observed in panic disorder (PD), obsessive compulsive disorder (OCD) and generalized anxiety disorder (GAD), and is thought to relate to dy...

journal_title：Neuroscience letters

authors： Simmons A,Matthews SC,Paulus MP,Stein MB

更新日期：2008-01-10 00:00:00

abstract：:Several studies have suggested an important role for brain-derived neurotrophic factor (BDNF) in the pathophysiology and therapeutics of bipolar disorder (BPD). The mechanisms underlying the therapeutic effects of lithium in BPD seem to involve a direct regulation of neurotrophic cascades. However, no clinical study e...

journal_title：Neuroscience letters

authors： de Sousa RT,van de Bilt MT,Diniz BS,Ladeira RB,Portela LV,Souza DO,Forlenza OV,Gattaz WF,Machado-Vieira R

更新日期：2011-04-20 00:00:00

abstract：:Gelsolin (GSN) levels and matrix metalloproteinase 3 (MMP3) activity have been found to be altered in the plasma in patients with Alzheimer disease (AD). The aim of this study was to determine whether a combination of these proteins with clinical data is specific and sensitive enough for AD diagnosis. In 113 non-demen...

journal_title：Neuroscience letters

authors： Peng M,Jia J,Qin W

更新日期：2015-05-19 00:00:00

abstract：:Male, Fischer-344 rats were pretreated with MK-801 (0.1, 1.0 or 10.0 mg/kg, i.p.) prior to bilateral injection of kainate (0.33 micrograms/site) into the dorsal and ventral hippocampus. Kainate impaired the acquisition of a water maze acquisition task 4 weeks after surgery, an effect not attenuated by pretreatment wit...

journal_title：Neuroscience letters

authors： Rogers BC,Tilson HA

更新日期：1990-02-16 00:00:00

abstract：:While past research suggests that ghrelin stimulates appetite through an action on hypothalamic signaling, recent evidence indicates that the peptide acts via mesotelencephalic dopamine neurons to alter appetitive motivation. In the present study, rats were trained to operantly respond for food on a progressive ratio ...

journal_title：Neuroscience letters

authors： Weinberg ZY,Nicholson ML,Currie PJ

更新日期：2011-07-20 00:00:00

abstract：:In situ whole cell voltage clamp recordings of presumed folliculo-stellate cells were made in the intermediate lobe of the clawed toad Xenopus laevis. Lucifer Yellow fillings revealed, in addition to the small, spherical melanotropes, a population of larger cells with many processes that were, to a limited extent, dye...

journal_title：Neuroscience letters

authors： Borst JG,Lodder JC,Roubos EW,Kits KS

更新日期：1996-05-03 00:00:00

abstract：:In this article, we investigated the autophosphorylation and translocation of calcium/calmodulin-dependent protein kinase II alpha (CaMKII alpha) in hippocampus during global ischemia. The following results were observed: (1) CaMKII alpha immediately became autophosphorylated after 3 min ischemia, at the same time, th...

journal_title：Neuroscience letters

authors： Meng F,Zhang G

更新日期：2002-11-15 00:00:00

abstract：:Afferent baroreceptor information is transmitted to the nucleus tractus solitarius (NTS) in the dorsal medulla where glutamate is thought to be the primary neurotransmitter. However, the subtypes of glutamate receptors involved in the baroreflex remain to be established. The present study compared the distribution of ...

journal_title：Neuroscience letters

authors： Botsford SA,Dean C,Hopp FA,Seagard JL

更新日期：1999-02-12 00:00:00

abstract：:Intracellular recordings from luminosity-type horizontal cells of the turtle retina were used to analyze the effects of steady and flickering background illumination on the size of their receptive fields. Both types of background illumination reduce the size of the receptive field to about the same extent. The reducti...

journal_title：Neuroscience letters

authors： Weiler R,Akopian A

更新日期：1992-06-08 00:00:00

abstract：:The in vivo effects of the alpha 2-adrenoceptor idazoxan, rauwolscine and phentolamine on alpha 2-auto/heteroreceptors and 5-HT1A autoreceptors modulating the synthesis of dopa/noradrenaline and 5-HTP/serotonin were assessed in rats, using the accumulation of dopa and 5-HTP after decarboxylase inhibition as a measure ...

journal_title：Neuroscience letters

authors： Lladó J,Esteban S,García-Sevilla JA

更新日期：1996-11-01 00:00:00

abstract：:The effect of methionine-enkephalin (Met-Enk) on responses of rat brain neostriatum neurones to microiontophoretic application of glutamate was studied in experiments with extracellular recording of spike activity. Met-Enk administered by microiontophoresis was shown to depress the glutamate-induced responses. In para...

journal_title：Neuroscience letters

authors： Kuznetsov VI,Godukhin OV

更新日期：1985-06-12 00:00:00

abstract：:Our previous study demonstrated that successive electroacupuncture (EA) at ST36 acupoint reduces IgE production in BALB/c mice immunized with 2,4-dinitrophenylated keyhole limpet protein (DNP-KLH) by suppression of the Th2 cell lineage development. Here, we report that pretreatment of phentolamine (alpha-adrenoceptor ...

journal_title：Neuroscience letters

authors： Lee Y,Kim SK,Kim Y,Lee H,Shin MK,Hong MC,Min BI,Bae H

更新日期：2007-08-16 00:00:00

abstract：:The distribution of astrocytes has been studied in whole-mounted horse and monkey retinae by the immunocytochemical localization of glial fibrillary acidic protein (GFAP). In the horse, astrocytes were found to be restricted to a narrow zone close to the optic nerve head. This is also the only region of the horse reti...

journal_title：Neuroscience letters

authors： Schnitzer J

更新日期：1987-07-09 00:00:00

abstract：:Vlgr1 (very large G-protein coupled receptor 1) knockout mice against hybrid backgrounds of the 129/Ola and C57BL/6 mouse strains show hearing deficit and high susceptibility to audiogenic seizures. The present study examined how hearing impairment and susceptibility to audiogenic seizures in Vlgr1-deficient mice chan...

journal_title：Neuroscience letters

authors： Yagi H,Noguchi Y,Kitamura K,Sato M

更新日期：2009-09-18 00:00:00

abstract：:Many experimental observations have demonstrated the modulatory role exerted by several neural structures and neurotransmitters on spontaneous and paroxysmal bioelectric activity of the hippocampus. Recently, the control exerted by locus coeruleus (LC) and its noradrenergic (NA) efferent pathway on different experimen...

journal_title：Neuroscience letters

authors： Ferraro G,Sardo P,Sabatino M,Caravaglios G,La Grutta V

更新日期：1994-03-14 00:00:00

abstract：:The nucleus accumbens (NAc) shell is closely associated with reward, psychiatric disorders (depression or schizophrenia), and drug abuse. Dopamine, released from the ventral tegmental area, is involved in these physiological functions and pathophysiological changes of NAc shell. Medium spiny neurons (MSNs), which are ...

journal_title：Neuroscience letters

authors： Kohnomi S,Ebihara K,Kobayashi M

更新日期：2017-01-01 00:00:00