Abstract:
:Afferent baroreceptor information is transmitted to the nucleus tractus solitarius (NTS) in the dorsal medulla where glutamate is thought to be the primary neurotransmitter. However, the subtypes of glutamate receptors involved in the baroreflex remain to be established. The present study compared the distribution of immunohistochemically labeled ionotropic receptor subtypes to the distribution of physiologically stimulated barosensitive neurons in the NTS of the dog and also identified ionotropic receptor subtypes located on barosensitive neurons. Both NMDA and non-NMDA receptors were located in barosensitive areas and on barosensitive neurons, suggesting that both may be involved in the baroreflex.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Botsford SA,Dean C,Hopp FA,Seagard JLdoi
10.1016/s0304-3940(98)00987-2keywords:
subject
Has Abstractpub_date
1999-02-12 00:00:00pages
113-7issue
1-2eissn
0304-3940issn
1872-7972pii
S0304-3940(98)00987-2journal_volume
261pub_type
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