Persistence of Inoue-Melnick virus and antibody in cerebrospinal fluid.

Abstract:

:Serial cerebrospinal fluid samples were obtained from 14 multiple sclerosis patients over a period of several months and were tested under code for Inoue-Melnick virus. In five of the positive patients, virus was present in 28 of 32 specimens collected over a period of 2 to 5 months. Four patients, from whom a total of 34 specimens were taken, yielded only a single isolate each. Five patients contributed 28 specimens, all of which were negative. In six patients (three virus positive and three virus negative), neutralizing antibody was detected in serum and in cerebrospinal fluid.

journal_name

J Clin Microbiol

authors

Melnick JL,Seidel E,Wang SS,Muchinik G,Rashti EJ,Jacobs LD,Freeman AI,O'Malley J

doi

10.1128/JCM.22.4.651-653.1985

subject

Has Abstract

pub_date

1985-10-01 00:00:00

pages

651-3

issue

4

eissn

0095-1137

issn

1098-660X

journal_volume

22

pub_type

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