Transformation of mouse bone marrow cells by transfection with a human oncogene related to c-myc is associated with the endogenous production of macrophage colony stimulating factor 1.

abstract：:Endothelin-1 production is increased after liver injury and the subsequent wounding response. Further, endothelin-1 has prominent effects on hepatic stellate cells (key effectors of the hepatic wounding response), including on collagen synthesis, proliferation, and expression of smooth muscle proteins. We tested the h...

journal_title：Journal of cellular physiology

authors： Shao R,Rockey DC

更新日期：2002-06-01 00:00:00

abstract：:Islet cell transplantation, as a treatment of type 1 diabetes, has a lot of complexity such as allograft rejections and an insufficient number of donors. The liver can be used as a replacement for endogenous insulin production. Hepatocytes can inherently respond to glucose levels and secrete proteins. Utilization of m...

journal_title：Journal of cellular physiology

authors： Beikmohammadi L,Bandehpour M,Hashemi SM,Kazemi B

更新日期：2019-08-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer and a leading cause of cancer-related death worldwide. About 1.8 million new cases were reported in 2018. Accordingly, there is an urgent need for development of effective strategies to lower the mortality and morbidity originated from this malignancy. MicroRNAs ...

journal_title：Journal of cellular physiology

authors： Anvarnia A,Mohaddes-Gharamaleki F,Asadi M,Akbari M,Yousefi B,Shanehbandi D

更新日期：2019-12-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) remains the leading cause of cancer death worldwide. As a platinum-based chemotherapeutic drug, cisplatin has been used in the NSCLC treatment for over 30 years, and its effects are impaired by drug resistance. This study aimed to investigate the potential role of lncRNA-AC078883.3 i...

journal_title：Journal of cellular physiology

authors： Xing S,Qu Y,Li C,Huang A,Tong S,Wu C,Fan K

更新日期：2019-12-01 00:00:00

abstract：:Urotensin II (UII), a vasoactive peptide modulates renal hemodynamics. However, the physiological functions of UII in glomerular cells are unclear. In particular, whether UII alters mesangial tone remains largely unknown. The present study investigates the physiological effects of UII on glomerular mesangial cells (GM...

journal_title：Journal of cellular physiology

authors： Adebiyi A

更新日期：2014-04-01 00:00:00

abstract：:In response to metabolic stress, GLUT4, the most abundant glucose transporter, translocates from intracellular vesicles to the plasma membrane. This appears to play an important role in protecting cardiac myocytes from ischemic injury. To investigate the precise mechanisms of GLUT4 translocation in cardiomyocytes, we ...

journal_title：Journal of cellular physiology

authors： Horie T,Ono K,Nagao K,Nishi H,Kinoshita M,Kawamura T,Wada H,Shimatsu A,Kita T,Hasegawa K

更新日期：2008-06-01 00:00:00

abstract：:Tumor suppressor pRb2/p130 gene belongs to the retinoblastoma (Rb) gene family, which also includes pRb/p105 and pRb/p107. The members of the Rb gene family have attracted a great deal of interest because of their essential role in regulating cell cycle and, consequently, cell proliferation. This mini review discusses...

journal_title：Journal of cellular physiology

authors： Giordano A,Rossi A,Romano G,Bagella L

更新日期：2007-11-01 00:00:00

abstract：:Human lymphocytes were equilibrated for 48 hours at 5-6 mM K+ ex over a range of temperatures between 0 and 37 degrees C, and at 5 degrees C over a range of external K+ levels between 0 and 32 mM. Cell K+ and Na+ contents are normal between 37 and 10 decrees. Below 10 degrees there is a critical thermal transition in ...

journal_title：Journal of cellular physiology

authors： Negendank W,Shaller C

更新日期：1980-04-01 00:00:00

abstract：:Butyrate and acetate are bacterial metabolites present in the large intestine lumen. Although butyrate is well known to inhibit the in vitro proliferation of human colon carcinoma cells in a process involving the hyperacetylation of specific nuclear histones, little is known about the possible link between butyrate me...

journal_title：Journal of cellular physiology

authors： Andriamihaja M,Chaumontet C,Tome D,Blachier F

更新日期：2009-01-01 00:00:00

abstract：:Mouse L-929 cells were subjected to increasing concentrations of sorbitol, which remove cell water and reduce volume osmotically. The rate of lactate production from glucose was significantly higher in osmotically perturbed cells than in controls, both in monolayers and in suspensions. L cells can apparently use sorbi...

journal_title：Journal of cellular physiology

authors： Clegg JS,Jackson SA,Fendl K

更新日期：1990-02-01 00:00:00

abstract：:Dexamethasone (Dex), a synthetic glucocorticoid (GC) with long-lasting treatment effects, has been proved to exert a modulatory effect on osteoblast proliferation and differentiation during embryonic osteogenesis. However, it is still controversial if Dex exposure influences endochondral ossification and the underlyin...

journal_title：Journal of cellular physiology

authors： Xu S,Guo R,Li PZ,Li K,Yan Y,Chen J,Wang G,Brand-Saberi B,Yang X,Cheng X

更新日期：2019-01-22 00:00:00

abstract：:Syndecans (SDCs) are a family of heparan sulfate proteoglycans (HSPGs) glycoproteins ubiquitously expressed on the cell surfaces and extracellular matrix of all mammalian tissues. There are four mammalian syndecans, SDC-1 thorough 4, which play a critical role in cell adhesion, migration, proliferation, differentiatio...

journal_title：Journal of cellular physiology

authors： Agere SA,Kim EY,Akhtar N,Ahmed S

更新日期：2018-09-01 00:00:00

abstract：:The aim of our studies was to identify miRNAs affecting the release of the major ovarian steroid hormones progestagen, androgen and estrogen by human ovarian cells. The effect of transfection of cultured primary ovarian granulosa cells with 80 different gene constructs encoding human pre-miRNAs on release of progester...

journal_title：Journal of cellular physiology

authors： Sirotkin AV,Ovcharenko D,Grossmann R,Lauková M,Mlyncek M

更新日期：2009-05-01 00:00:00

abstract：:Two transport systems for neutral amino acids have been characterised in LLC-PK, cells. The first, which transports alanine in a sodium-dependent manner, also mediates alanine exchange and is perferentially inhibited by serine, cysteine, and alpha-amino-n-butyric acid. This system resembles the ASC system in Ehrlich a...

journal_title：Journal of cellular physiology

authors： Sepúlveda FV,Pearson JD

更新日期：1982-08-01 00:00:00

abstract：:Myocardium infarction is one of the most deathly cardiovascular diseases. It is characterized by myocardium ischemia as a result of nutrients depletion and hypoxia. The cell can respond to this injury by autophagy or apoptosis, which determines the evolution and possible recovery of the myocardium infarction. Lipids p...

journal_title：Journal of cellular physiology

authors： Sousa B,Melo T,Campos A,Moreira AS,Maciel E,Domingues P,Carvalho RP,Rodrigues TR,Girão H,Domingues MR

更新日期：2016-10-01 00:00:00

abstract：:The growth-regulated vimentin gene contains a functional double AP-1 binding site formed by two nearly perfect inverted repeats. We present evidence for down-regulation of vimentin expression by the retinoic acid receptor (RAR) in two mesodermally derived cell types. By mutation analysis we prove that the double conse...

journal_title：Journal of cellular physiology

authors： Van de Klundert FA,Jansen HJ,Bloemendal H

更新日期：1995-07-01 00:00:00

abstract：:Acute lung injury, sepsis, lung inflammation, and ventilator-induced lung injury are life-threatening conditions associated with lung vascular barrier dysfunction, which may lead to pulmonary edema. Increased levels of atrial natriuretic peptide (ANP) in lung circulation reported in these pathologies suggest its poten...

journal_title：Journal of cellular physiology

authors： Birukova AA,Zagranichnaya T,Alekseeva E,Bokoch GM,Birukov KG

更新日期：2008-06-01 00:00:00

abstract：:Circular RNAs (circRNAs) have been associated with lung cancer (LC), one of the most common cancers, but the underlying molecular mechanisms of the specific correlation with LC carcinogenesis remain unveiled. Quantitative real-time polymerase chain reaction was applied to examine the level of circZNF609. LC cells were...

journal_title：Journal of cellular physiology

authors： Liu S,Yang N,Jiang X,Wang J,Dong J,Gao Y

更新日期：2021-01-01 00:00:00

abstract：:Damage-associated molecular patterns, including mitochondrial DNA (mtDNA) are released during hemorrhage resulting in the development of endotheliopathy. Tranexamic acid (TXA), an antifibrinolytic drug used in hemorrhaging patients, enhances their survival despite the lack of a comprehensive understanding of its cellu...

journal_title：Journal of cellular physiology

authors： Prudovsky I,Carter D,Kacer D,Palmeri M,Soul T,Kumpel C,Pyburn K,Barrett K,DeMambro V,Alexandrov I,Brandina I,Kramer R,Rappold J

更新日期：2019-11-01 00:00:00

abstract：:Cover: The cover image, by Michaela R. Reagan et al., is based on the Perspective A Perspective on Malignancy in the Marrow, DOI 10.1002/jcp.25860. ...

journal_title：Journal of cellular physiology

authors： Reagan MR,Lian JB,Rosen CJ,Stein GS

更新日期：2017-12-01 00:00:00

abstract：:Production of inflammatory cytokines plays important roles in the response against tissue injury and in host defense. Alterations in the production of inflammatory cytokines may cause local or systemic inflammatory imbalance, culminating in organ failure or lethal systemic inflammation. The cholinergic anti-inflammato...

journal_title：Journal of cellular physiology

authors： Pereira MR,Leite PE

更新日期：2016-09-01 00:00:00

abstract：:Mitochondrial transcription factor A (TFAM) is responsible for stability, maintenance, and transcriptional control of mitochondrial DNA (mtDNA). We have studied the expression and distribution of TFAM in the gametes and preimplantation embryos of the domestic pig (Sus scrofa). We hypothesized that TFAM is not present ...

journal_title：Journal of cellular physiology

authors： Antelman J,Manandhar G,Yi YJ,Li R,Whitworth KM,Sutovsky M,Agca C,Prather RS,Sutovsky P

更新日期：2008-11-01 00:00:00

abstract：:1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) and the vitamin D receptor (VDR) have been reported to have an important role in the regulation of innate immunity. We earlier reported that the antimicrobial peptide cathelicidin is induced by 1,25(OH)2D3 in normal human bronchial epithelial cells with a resultant increase in an...

journal_title：Journal of cellular physiology

authors： Dhawan P,Wei R,Sun C,Gombart AF,Koeffler HP,Diamond G,Christakos S

更新日期：2015-02-01 00:00:00

abstract：:Well-coupled mitochondria were isolated from a HuH13 line of human hepatoma cells and human liver tissue. The liver mitochondria showed a feeble glutamine oxidation activity in contrast to the hepatoma mitochondria, whereas they utilized glutamate well for the oxidative phosphorylation. In the liver mitochondria, glut...

journal_title：Journal of cellular physiology

authors： Matsuno T

更新日期：1991-08-01 00:00:00

abstract：:The untransformed stable cell line Met murine hepatocytes (MMH), generated from liver explants of transgenic mice expressing a constitutively active truncated form of the human hepatocyte growth factor receptor (cyto-Met), represents an innovative tool for in vitro studies of liver function. In the present report, we ...

journal_title：Journal of cellular physiology

authors： Bellovino D,Lanyau Y,Garaguso I,Amicone L,Cavallari C,Tripodi M,Gaetani S

更新日期：1999-10-01 00:00:00

abstract：:Tumors and multicellular tumor spheroids can develop gradients in oxygen concentration, glucose concentration, and extracellular pH as they grow. In order to calculate these gradients and assess their impact on tumor growth, it is necessary to quantify the effect of these variables on tumor cell metabolism and growth....

journal_title：Journal of cellular physiology

authors： Casciari JJ,Sotirchos SV,Sutherland RM

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Elevated microsatellite alteration at selected tetranucleotide repeats (EMAST) is a type of microsatellite instability that occurs in ∼60% of colorectal cancers (CRCs) and associated with MSH3 dysfunction. A 5-fluorouracil (5-FU)-related cytotoxicity is attenuated in MSH3-deficient colon cancer cells. Report...

journal_title：Journal of cellular physiology

authors： Mohammadpour S,Goodarzi HR,Jafarinia M,Porhoseingholi MA,Nazemalhosseini-Mojarad E

更新日期：2020-04-01 00:00:00

abstract：:Pyroptosis, a type of programmed cell death mediated by gasdermin, is characterized by the swelling and rupture of cells, release of cellular contents and a strong inflammatory response, which is critical for controlling microbial infection. Pattern recognition receptors recognize the intracellular and extracellular p...

journal_title：Journal of cellular physiology

authors： Xia X,Wang X,Zheng Y,Jiang J,Hu J

更新日期：2019-06-01 00:00:00

abstract：:We have previously demonstrated that kidney embryonic structures are present in rats, and are still developing until postnatal Day 20. Consequently, at postnatal Day 10, the rat renal papilla contains newly formed collecting duct (CD) cells and others in a more mature stage. Performing primary cultures, combined with ...

journal_title：Journal of cellular physiology

authors： Del Valle Guaytima E,Brandán YR,Favale NO,Sterin-Speziale NB,Márquez MG

更新日期：2019-08-01 00:00:00

abstract：:Over-production and activation of osteoclasts is a common feature of osteolytic conditions such as osteoporosis, tumor-associated osteolysis, and inflammatory bone erosion. Cyanidin Chloride, a subclass of anthocyanin, displays antioxidant and anti-carcinogenesis properties, but its role in osteoclastic bone resorptio...

journal_title：Journal of cellular physiology

authors： Cheng J,Zhou L,Liu Q,Tickner J,Tan Z,Li X,Liu M,Lin X,Wang T,Pavlos NJ,Zhao J,Xu J

更新日期：2018-03-01 00:00:00