RGS2 regulates urotensin II-induced intracellular Ca2+ elevation and contraction in glomerular mesangial cells.

abstract：:EL 4-6.1 cells, variants of the murine EL4 thymoma cell line, can be activated by interleukin 1 (IL-1) or phorbol 12-myristate-13-acetate (PMA), or PMA+IL-1 to secrete interleukin 2 (IL-2) and interleukin 4 (IL-4) and to express the IL-2 receptor (IL-2R). To compare the different activation pathways, we examined the e...

journal_title：Journal of cellular physiology

authors： Dornand J,Bouaboula M,d'Angeac AD,Favero J,Shire D,Casellas P

更新日期：1992-04-01 00:00:00

abstract：:Nerve growth factor (NGF) is required for the growth and development of sensory and sympathetic neurons. Incubation of chick dorsal root ganglionic cells without NGF resulted in a decrease of active (Na+,K+-pump-mediated) K+ influx over a period of several hours. Addition of NGF to NGF-deprived cells caused 1) a retur...

journal_title：Journal of cellular physiology

authors： Boonstra J,Skaper SD,Varon S

更新日期：1982-10-01 00:00:00

abstract：:Fibrosis is a common pathological condition associated with abnormal repair after tissue injury. However, the etiology and molecular mechanisms of fibrosis are still not well-understood. Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) belongs to the TNF superfamily and acts by binding to its recepto...

journal_title：Journal of cellular physiology

authors： Zhang Y,Zeng W,Xia Y

更新日期：2020-09-30 00:00:00

abstract：BACKGROUND:Elevated microsatellite alteration at selected tetranucleotide repeats (EMAST) is a type of microsatellite instability that occurs in ∼60% of colorectal cancers (CRCs) and associated with MSH3 dysfunction. A 5-fluorouracil (5-FU)-related cytotoxicity is attenuated in MSH3-deficient colon cancer cells. Report...

journal_title：Journal of cellular physiology

authors： Mohammadpour S,Goodarzi HR,Jafarinia M,Porhoseingholi MA,Nazemalhosseini-Mojarad E

更新日期：2020-04-01 00:00:00

abstract：:Elevated oxidative stress plays a key role in diabetes-associated vascular disease. In this study, we tested the hypothesis that high glucose-induced oxidative stress was associated with changes in the expression of NADPH oxidase, superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS). Oxidative stres...

journal_title：Journal of cellular physiology

authors： Ding H,Aljofan M,Triggle CR

更新日期：2007-09-01 00:00:00

abstract：:Cdk9, a member of the cyclin-dependent kinase family, is the catalytic subunit of P-TEFb, a protein kinase complex that stimulates transcriptional elongation. Cdk9, complexed with its regulatory partner cyclin T1, serves as the cellular mediator of the transactivation function of the HIV Tat protein. There are two kno...

journal_title：Journal of cellular physiology

authors： Liu H,Herrmann CH

更新日期：2005-04-01 00:00:00

abstract：:Interleukin-10 (IL-10) has been shown to exert anti-inflammatory effects by suppressing macrophage proliferation and inhibiting cytokine production. In this study we show that in the presence of erythropoietin (EPO), the addition of IL-10 results in a significant dose-dependent increase in both Burst Forming Unit-Eryt...

journal_title：Journal of cellular physiology

authors： Wang CQ,Udupa KB,Lipschitz DA

更新日期：1996-02-01 00:00:00

abstract：:Sulfogalactosylglycerolipid (SGG) is the major mammalian male germ cell glycolipid and has been implicated in sperm/egg binding. Mycoplasma pulmonis, a species of Mollicutes, is associated with male infertility in rodents. Purified SGG incubated in the presence of M. pulmonis was enzymatically degraded by both desulfa...

journal_title：Journal of cellular physiology

authors： Lingwood C,Schramayr S,Quinn P

更新日期：1990-01-01 00:00:00

abstract：:The amino acid pools in Chinese hamster lung V79 cells were measured as a function of time during hyperthermic exposure at 40.5 degrees and 45.0 degrees C. Sixteen of the 20 protein amino acids were present in sufficient quantity to measure accurately. The total amino acid pool and all individual amino acids, except g...

journal_title：Journal of cellular physiology

authors： Goh CJ,Dumbroff EB,Lepock JR

更新日期：1988-04-01 00:00:00

abstract：:Inhibition of insulin-induced 3T3-L1 preadipocyte differentiation by rapamycin has been attributed to a blockade of the early critical clonal expansion phase of the adipogenic program. Rapamycin binds to, and inhibits, mTOR (mammalian target of rapamycin), leading to diminution of p70 S6 kinase activity and eukaryotic...

journal_title：Journal of cellular physiology

authors： Gagnon A,Lau S,Sorisky A

更新日期：2001-10-01 00:00:00

abstract：:Thioredoxin reductase (TrxR) is a flavoprotein that contains a C-terminal penultimate selenocysteine (Sec) and has an ability to reduce thioredoxin (Trx), which regulates the activity of NF-kappa B. To date, three TrxR isozymes, TrxR1, TrxR2, and TrxR3, have been identified. In the present study, we found that among t...

journal_title：Journal of cellular physiology

authors： Sakurai A,Yuasa K,Shoji Y,Himeno S,Tsujimoto M,Kunimoto M,Imura N,Hara S

更新日期：2004-01-01 00:00:00

abstract：:In this study, we compared qualitative and quantitative changes in the lateral mobility of phospholipid molecules in the plasma membrane of intact cells under various conditions of specific interaction of integrins in the cell membrane with two extracellular matrix (ECM) components viz. fibronectin (FN) and laminin (L...

journal_title：Journal of cellular physiology

authors： Ramprasad OG,Rangaraj N,Srinivas G,Thiery JP,Dufour S,Pande G

更新日期：2008-05-01 00:00:00

abstract：:Cancer cells acquire dysregulated gene expression to establish specific transcriptional dependencies and their underlying mechanisms that are ultimately responsible for this addictions have not been fully elucidated. Glucose-regulated protein 78 (GRP78) is a stress-inducible, multifunctional, prosurvival, endoplasmic ...

journal_title：Journal of cellular physiology

authors： Gopal U,Pizzo SV

更新日期：2020-08-31 00:00:00

abstract：:The C3H/10T 1/2 embryo cell line, which is nontumorigenic when inoculated subcutaneously in saline suspension, produces tumors when implanted subcutaneously attached to 1 X 5 X 10 mm plastic plates. Under these in vivo conditions there is direct selection for "spontaneous" transformants that have undergone the specifi...

journal_title：Journal of cellular physiology

authors： Paranjpe M,del Ande Eaton S,Boone CW

更新日期：1978-07-01 00:00:00

abstract：:Nucleotides released from cells due to stress, injury or inflammation, induce mitogenic effects in monocytes via activation of P2Y(2) nucleotide receptors (P2Y(2)Rs). Here we show that P2Y(2) nucleotide receptors in U937 monocytic cells regulate the activation of extracellular signal-regulated kinases 1 and 2 (ERK 1/2...

journal_title：Journal of cellular physiology

authors： Chorna NE,Chevres M,Santos-Berrios C,Orellano EA,Erb L,González FA

更新日期：2007-05-01 00:00:00

abstract：:Stromal cell-derived factor-1 (SDF-1) and CXC chemokine receptor 4 (CXCR4) have been found to be tightly correlated with the progression of prostate cancer (PC). In this study, we investigated the effects of an SDF-1α/CXCR4 inhibitor, AMD3100, on cell progression and metastasis potential of human PC cells. Human PC ce...

journal_title：Journal of cellular physiology

authors： Zhu WB,Zhao ZF,Zhou X

更新日期：2019-07-01 00:00:00

abstract：:Baculoviral IAP repeat containing 5 (BIRC5) gene encodes the important protein as survivin, a multifunctional protein, which is involved in cellular and molecular networks, progression of cell cycle, homeostasis, developmental morphogenesis, and apoptosis. The proximal BIRC5 promoter possesses specific binding sites f...

journal_title：Journal of cellular physiology

authors： Pahlavan Y,Kahroba H,Samadi N,Karimi A,Ansarin K,Khabbazi A

更新日期：2019-11-01 00:00:00

abstract：:Vitamin E, a dietary antioxidant, is presumed to be incorporated into the lipid bilayer of biological membranes to an extent proportional to the amount of polyunsaturated fatty acids or phospholipids in the membrane. In the present study we evaluated the distribution of incorporated polyunsaturated fatty acids (PUFA) ...

journal_title：Journal of cellular physiology

authors： Sekharam KM,Patel JM,Block ER

更新日期：1990-12-01 00:00:00

abstract：:Members of the epidermal growth-factor-receptor tyrosine-kinase (EGFR) family play important roles both in normal growth regulation/cell differentiation and in the genesis and progression of human neoplasia. In the present study, we analysed distinct heregulin (HRG) signals mediated by the HRG receptors HER3 and HER4....

journal_title：Journal of cellular physiology

authors： Weiss FU,Wallasch C,Campiglio M,Issing W,Ullrich A

更新日期：1997-11-01 00:00:00

abstract：:The vagina provides a characteristic low-Na+ and low-pH fluid microenvironment that is considered generally protective. Previous studies have shown that various types of epithelial cells harbor the capacity of intracellular pH (pHi) regulation. However, it remains elusive whether vaginal epithelium could actively regu...

journal_title：Journal of cellular physiology

authors： Zhang YL,Feng JC,Ke LJ,Xu JW,Huang ZX,Huang J,Zhu YX,Zhou WL

更新日期：2019-01-29 00:00:00

abstract：:Cells from kidney proximal tubules have been successfully isolated, characterized, and cultured from male Fischer 344 rats between 150-400 g using a two-step collagenase perfusion. The cells undergo high levels of DNA synthesis and mitosis in both serum free media (with an without hormone supplementation) and media co...

journal_title：Journal of cellular physiology

authors： Rosenberg MR,Michalopoulos G

更新日期：1987-04-01 00:00:00

abstract：:The role of hsp27 as an inhibitor of actin polymerization was considered in the context of the actin cytoskeleton and its relationship with focal adhesion formation. The aim of this study was to evaluate the potential effects of hsp27 on focal adhesion formation as a relevant biological consequence of actin stress fib...

journal_title：Journal of cellular physiology

authors： Schneider GB,Hamano H,Cooper LF

更新日期：1998-12-01 00:00:00

abstract：:Somatic cell hybrids between either normal human fibroblasts, phenotypically normal mouse fibroblasts or mouse peritoneal macrophages and HT1080 human diploid fibrosarcoma cells were studied for their ability to form tumors in nude mice. The results of this study indicate that tumorigenic behavior is expressed as a do...

journal_title：Journal of cellular physiology

authors： Croce CM,Barrick J,Linnenbach A,Koprowski H

更新日期：1979-06-01 00:00:00

abstract：:Formation of human T lymphocyte colonies in semisolid medium from T lymphocyte colony-forming units (TL-CFUs) under stimulation of phytohemagglutinin (PHA) has been reported by several authors. These TL-CFUs were present in unsensitized lymphocyte populations. We report here that such TL-CFUs are capable of renewing t...

journal_title：Journal of cellular physiology

authors： Wu AM

更新日期：1983-10-01 00:00:00

abstract：:Vitamin D3 metabolites regulate the differentiation of chondrocytes isolated from the growth zone or resting zone of rat costochondral cartilage. Since some of the direct membrane effects of vitamin D metabolites are nongenomic, we hypothesized that protein kinase C (PKC) plays a role in signal transduction for these ...

journal_title：Journal of cellular physiology

authors： Sylvia VL,Schwartz Z,Schuman L,Morgan RT,Mackey S,Gomez R,Boyan BD

更新日期：1993-11-01 00:00:00

abstract：:The serum-free medium conditioned by the human colon cancer cell line HT-29 contains insulin-like growth factors (IGF) that are entirely complexed to binding proteins (IGF-BP). Gel filtration in acid conditions of the cell-conditioned medium permits separation of IGF-BP from two molecular forms of IGF of 15,000 and 7,...

journal_title：Journal of cellular physiology

authors： Culouscou JM,Remacle-Bonnet M,Garrouste F,Fantini J,Marvaldi J,Pommier G

更新日期：1990-06-01 00:00:00

abstract：:Apoptosis is involved in both the cellular and humoral immune system destroying tumors. An apoptosis-inducing factor from HL-60 myeloid leukemia cells was obtained, purified, and sequenced. The protein found has been identified as a human complement factor B-derived fragment Bb, although it is known that factor B is a...

journal_title：Journal of cellular physiology

authors： Uwai M,Terui Y,Mishima Y,Tomizuka H,Ikeda M,Itoh T,Mori M,Ueda M,Inoue R,Yamada M,Hayasawa H,Horiuchi T,Niho Y,Matsumoto M,Ishizaka Y,Ikeda K,Ozawa K,Hatake K

更新日期：2000-11-01 00:00:00

abstract：:The role of the plasma membrane potential (delta psi p) in the commitment to differentiation of murine erythroleukemia (MEL) cells has been studied by analyzing the ionic basis and the time course of this potential in the absence or the presence of different types of inducers. delta psi p was determined by measuring t...

journal_title：Journal of cellular physiology

authors： Arcangeli A,Ricupero L,Olivotto M

更新日期：1987-09-01 00:00:00

abstract：:Epidermal growth factor (EGF) has been shown rapidly to inhibit the transition from G2 phase to mitosis: beyond this transition point the cells are refractory to EGF (Kinzel et al., 1990, Cancer Res., 50:7932-7936). Using synchronized HeLa cells, EGF has now been shown to induce an overall decrease of the histone H1 k...

journal_title：Journal of cellular physiology

authors： Barth H,Kinzel V

更新日期：1995-01-01 00:00:00

abstract：:Bone morphogenetic protein-2 (BMP-2), a member of transforming growth factor-beta superfamily, plays a crucial role in migration and metastasis of human cancer cells. Integrins are the major adhesive molecules in mammalian cells. Here we found that BMP-2 directed the migration and increased cell surface and mRNA expre...

journal_title：Journal of cellular physiology

authors： Fong YC,Li TM,Wu CM,Hsu SF,Kao ST,Chen RJ,Lin CC,Liu SC,Wu CL,Tang CH

更新日期：2008-12-01 00:00:00