Characterization of neutral amino acid uptake by cultured epithelial cells from pig kidney.

abstract：:This study is carried out to elucidate the role of long noncoding RNAs (lncRNAs) MT1JP in proliferation, invasion, migration, and apoptosis of glioma cells through the regulation of PTEN/Akt signaling pathway. The expression of MT1JP in 80 normal brain tissues and 138 glioma tissues, as well as glioma cell lines, was ...

journal_title：Journal of cellular physiology

authors： Zhang Y,Sui R,Chen Y,Liang H,Shi J,Piao H

更新日期：2019-11-01 00:00:00

abstract：:MicroRNAs play an important regulatory role in the proliferation and differentiation of skeletal muscle-derived satellite cells (MDSCs). In particular, miR-139 can inhibit tumor cell proliferation and invasion, and its expression is down-regulated during C2C12 myoblast differentiation. The aim of this study was thus t...

journal_title：Journal of cellular physiology

authors： Zhou S,Li S,Zhang W,Tong H,Li S,Yan Y

更新日期：2018-01-01 00:00:00

abstract：:We have reported previously that the production of a tumor cell factor that stimulates synthesis of fibroblast collagenase is influenced by a fibroblast-deposited matrix component, possibly heparan sulfate-proteoglycan. In this study, binding sites for heparin and heparan sulfate on mouse B-16 melanoma cells have been...

journal_title：Journal of cellular physiology

authors： Biswas C

更新日期：1988-07-01 00:00:00

abstract：:Osteoblasts are terminally differentiated cells with mesenchymal origins, known to possess pivotal roles in sustaining bone microstructure and homeostasis. These cells are implicated in the pathophysiology of various bone disorders, especially osteoporosis. Over the last few decades, strategies to impede bone resorpti...

journal_title：Journal of cellular physiology

authors： Aslani S,Abhari A,Sakhinia E,Sanajou D,Rajabi H,Rahimzadeh S

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Disc degeneration is the common life-threatening disease characterized by flank pain. The gene expression of insulin-like growth factor binding protein 3 (IGFBP3) is increased in patients with disc degeneration, however, its mechanism is still unknown. This study aimed to investigate the influence of IGFBP3 g...

journal_title：Journal of cellular physiology

authors： Chen G,Zhou X,Xu Z

更新日期：2019-06-01 00:00:00

abstract：:Oral administration of ajulemic acid (AjA), a cannabinoid acid devoid of psychoactivity, prevents joint tissue injury in rats with adjuvant induced arthritis. Because activation of osteoclasts is central to the pathogenesis of bone erosion in patients with rheumatoid arthritis (RA), we investigated the influence of Aj...

journal_title：Journal of cellular physiology

authors： George KL,Saltman LH,Stein GS,Lian JB,Zurier RB

更新日期：2008-03-01 00:00:00

abstract：:Versican is a large chondroitin sulfate proteoglycan and belongs to the family of lecticans. Versican possesses two globular domains, G1 and G3 domain, separated by a CS-attachment region. The CS-attachment region present in the middle region is divided into two spliced domains named CSalpha and beta. Alternative spli...

journal_title：Journal of cellular physiology

authors： Sheng W,Dong H,Lee DY,Lu WY,Yang BB

更新日期：2007-04-01 00:00:00

abstract：:MicroRNAs (miRNAs) are a newly identified class of small regulatory non-coding endogenous RNAs that are ubiquitous from animals to plants and have pivotal functions in nearly all biological and metabolic processes. Increasing evidence shows that miRNAs are also new players regulating many protein-coding genes and spec...

journal_title：Journal of cellular physiology

authors： Chen D,Farwell MA,Zhang B

更新日期：2010-11-01 00:00:00

abstract：:We studied the influence of hydrocortisone (HC) on hyaluronan (HA) metabolism in explants of human skin, a model retaining normal three-dimensional architecture of dermal connective tissue and dynamic growth and stratification of epidermal keratinocytes. The synthesis of hyaluronan and proteoglycans (PGs), and DNA, we...

journal_title：Journal of cellular physiology

authors： Agren UM,Tammi M,Tammi R

更新日期：1995-08-01 00:00:00

abstract：:Runx2 and Runx3 are known to be expressed in the growth plate during endochondral bone formation. Here we addressed the functional role of Runx3 as distinct from Runx2 by using two models of postnatal bone repair: fracture healing that proceeds by an endochondral process and marrow ablation that proceeds by only an in...

journal_title：Journal of cellular physiology

authors： Wigner NA,Soung do Y,Einhorn TA,Drissi H,Gerstenfeld LC

更新日期：2013-11-01 00:00:00

abstract：:Cell- and matrix-related parameters, which characterize the aging and differentiation process of cartilage in vivo, were measured in cultured chick epiphyseal chondrocytes during maintenance in a suspension culture for 34 days. A gradual decrease in the rates of proliferation and an increase in the size of the cells w...

journal_title：Journal of cellular physiology

authors： Beit-Or A,Nevo Z,Kalina M,Eilam Y

更新日期：1990-08-01 00:00:00

abstract：:In Xenopus oocytes injected with total rat pituitary GH3 cell RNA, thyrotropin-releasing hormone (TRH) causes the activation of the inositol lipid transduction pathway and the induction of chloride conductance via calcium-activated channels (Oron et al., 1987, Mol. Endocrinol., 1:918-925). This response exhibits chara...

journal_title：Journal of cellular physiology

authors： Lipinsky D,Gershengorn MC,Oron Y

更新日期：1995-02-01 00:00:00

abstract：:The aim of the yearly National Congress of the Italian Society of Virology (SIV) is to promote the discussion between senior and younger researchers to improve the knowledge and scientific collaboration among the various areas of Virology. The invited and selected lecturers of the fourth National Congress of SIV cover...

journal_title：Journal of cellular physiology

authors： Salata C,Parolin C,Palù G

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) shows several kinds of disorders, which acutely harm the kidney. However, the current medical methods have limited therapeutic effects. The present study aimed to find out the molecular mechanism of AKI pathogenesis, which may provide new insights for future therapy. METHODS:Bioinf...

journal_title：Journal of cellular physiology

authors： Tian X,Ji Y,Liang Y,Zhang J,Guan L,Wang C

更新日期：2019-08-01 00:00:00

abstract：:The trabecular meshwork (TM) is a specialized tissue located at the chamber angle of the eye next to the cornea. This tissue is believed to be responsible for regulation of the aqueous humor outflow and control of the intraocular pressure (IOP). Alterations in functions of the TM may lead to IOP elevation and developm...

journal_title：Journal of cellular physiology

authors： Wentz-Hunter K,Ueda J,Shimizu N,Yue BY

更新日期：2002-01-01 00:00:00

abstract：:Mesenchymal stromal cells (MSCs) have been widely exploited for the treatment of several conditions due to their intrinsic regenerative and immunomodulatory properties. MSC have demonstrated to be particularly relevant for the treatment of ischemic diseases, where MSC-based therapies can stimulate angiogenesis and ind...

journal_title：Journal of cellular physiology

authors： Pinto DS,Ahsan T,Serra J,Fernandes-Platzgummer A,Cabral JMS,da Silva CL

更新日期：2020-10-01 00:00:00

abstract：:Restenosis after angioplasty or stent is a major clinical problem. While long noncoding RNAs (lncRNAs) are implicated in a variety of diseases, their role in restenosis is not well understood. This study aims to investigate how dysregulated lncRNAs and messenger RNAs (mRNAs) contribute to restenosis. By microarray ana...

journal_title：Journal of cellular physiology

authors： Zhou Y,He X,Liu R,Qin Y,Wang S,Yao X,Li C,Hu Z

更新日期：2019-02-10 00:00:00

abstract：:Methylxantine derivative, caffeine, is known to prevent the p53-dependent apoptosis pathway via inhibition of ATM (ataxia telangiectasia mutated) kinase, which activates p53 by phosphorylation of the Ser-15 residue. In contrast, it has been reported that caffeine induces p53-mediated apoptosis through Bax protein in n...

journal_title：Journal of cellular physiology

authors： Ito K,Nakazato T,Miyakawa Y,Yamato K,Ikeda Y,Kizaki M

更新日期：2003-08-01 00:00:00

abstract：:Human dental pulp stem cells (hDPSCs) show significant potential for exploitation in novel regeneration strategies, although lack of understanding of their responses to bacterial challenge constrains their application. The present study aimed to investigate whether lipopolysaccharide (LPS), the major pathogenic factor...

journal_title：Journal of cellular physiology

authors： He W,Wang Z,Luo Z,Yu Q,Jiang Y,Zhang Y,Zhou Z,Smith AJ,Cooper PR

更新日期：2015-03-01 00:00:00

abstract：:Tobacco smoking is associated with many diseases. Addiction is of the most notorious tobacco-related syndrome and is mainly attributed to nicotine. In this study, we employed Caenorhabditis elegans as a biological model to systemically investigate the effect of chronic nicotine exposure on microRNA (miRNA) expression ...

journal_title：Journal of cellular physiology

authors： Taki FA,Pan X,Zhang B

更新日期：2014-01-01 00:00:00

abstract：:In fertilized echinoderm eggs, the male and female pronuclei fuse to form the diploid nucleus even in the presence of aphidicolin, a specific inhibitor of eukaryotic DNA polymerase-alpha. The subsequent first cleavage is independent of chromosomes but dependent on spindle and amphiaster. The fate of DNA originally exi...

journal_title：Journal of cellular physiology

authors： Yamada H,Hirai S,Ikegami S,Kawarada Y,Okuhara E,Nagano H

更新日期：1985-07-01 00:00:00

abstract：:Bethanechol, a muscarinic agonist, inhibits the initial rate of amiloride-sensitive Na uptake by intact mucosa of avian small intestine as well as by isolated chicken villus enterocytes, an effect that is maximal at 90 seconds and reverses by 6 minutes. Bethanechol similarly decreases intracellular pH in isolated cell...

journal_title：Journal of cellular physiology

authors： Musch MW,Drabik-Arvans D,Rao MC,Chang EB

更新日期：1992-08-01 00:00:00

abstract：:Cytoplasmic poly-A containing RNA, synthesized by cultured chick embryo cells, was examined during growth in 5-bromodeoxyuridine. The kinetics of 3H-adenosine incorporation into this species of RNA, when compared to the rest of the cytoplasmic RNA, and to control cells, indicates that the rate of synthesis of this RNA...

journal_title：Journal of cellular physiology

authors： Pawlowski PJ

更新日期：1976-09-01 00:00:00

abstract：:Biochemical events elicited by interleukin 1 (IL-1) were studied in Swiss 3T3 fibroblasts. One hour after its addition, IL-1 stimulated synthesis of prostaglandin E2 (PGE2), which continued to accumulate for 4 days. IL-1 also stimulated cAMP accumulation. Indomethacin blocked cAMP accumulation in response to IL-1, sug...

journal_title：Journal of cellular physiology

authors： Burch RM,White MF,Connor JR

更新日期：1989-04-01 00:00:00

abstract：:Low-grade astrocytomas (LGAs) are the most common type of brain tumor in children. Until recently, very little was known about the underlying biology and molecular genetics of these tumors. However, within the past year a number of studies have shown that the MAPK pathway is constitutively activated in a high proporti...

journal_title：Journal of cellular physiology

authors： Tatevossian RG,Lawson AR,Forshew T,Hindley GF,Ellison DW,Sheer D

更新日期：2010-03-01 00:00:00

abstract：:Excessive generation of mitochondrial reactive oxygen species (ROS) is considered to be initiating event in the development of diabetic nephropathy (DN). Mitochondrial biosynthesis mediated by coactivator PGC-1α and its downstream transcription factors NRF1 and TFAM may be a key target in maintaining mitochondrial fun...

journal_title：Journal of cellular physiology

authors： Zhang T,Chi Y,Kang Y,Lu H,Niu H,Liu W,Li Y

更新日期：2019-04-01 00:00:00

abstract：:Cellular growth has been found to be directly related to the amount of sodium pumping activity in mouse lymphoblasts (L5178-Y) cultured in varying concentrations of the cardiac glycoside, ouabain. No short-term adaptation (within one generation) occured; i.e., neither growth rate nor (Na+ + K+)-ATPase activity increas...

journal_title：Journal of cellular physiology

authors： Shank BB,Smith NE

更新日期：1976-03-01 00:00:00

abstract：:BA10-IR transformed cells, obtained by treating Syrian hamster embryo fibroblasts (HEF) with 7-methylbenz(a)anthracene and cultivated for a long period, are highly tumorigenic and grow in suspension as aggregates (spheroids) (Levy et al., 1976). They also grow in attached form or as spheroids in serum-free (S-) synthe...

journal_title：Journal of cellular physiology

authors： Xin LW,Jullien P,Lawrence DA,Pironin M,Vigier P

更新日期：1987-05-01 00:00:00

abstract：:Spontaneously arising, TGF beta 1-resistant colonies were isolated directly from the soft agarose plates of MOSER human colon carcinoma cells grown in the presence of TGF beta 1 but in the absence of serum. The colonies were cloned by limiting dilution and screened in a monolayer proliferation assay for sensitivity to...

journal_title：Journal of cellular physiology

authors： Zhou GH,Sechrist GL,Brattain MG,Mulder KM

更新日期：1995-12-01 00:00:00

abstract：:Liver fibrosis is a reversible wound-healing response that occurs after liver injury. NADPH oxidases (NOXs) and reactive oxygen species (ROS) which are expressed in hepatocytes (HCs), hepatic stellate cells (HSCs), and Kupffer cells (KCs) play an important role in the development of hepatic fibrosis. In in vitro studi...

journal_title：Journal of cellular physiology

authors： Gan D,Zhang W,Huang C,Chen J,He W,Wang A,Li B,Zhu X

更新日期：2018-10-01 00:00:00