Modulation of the in vitro angiogenic potential of human mesenchymal stromal cells from different tissue sources.

abstract：:Malignant mesothelioma is an aggressive tumor of serosal surfaces, which is refractory to current treatment options. Arsenic trioxide (As2O3) is used clinically to treat acute promyelocytic leukemia, and also to inhibit proliferation of several solid tumors including hepatoma, esophageal, and gastric cancer in vitro. ...

journal_title：Journal of cellular physiology

authors： Eguchi R,Fujimori Y,Takeda H,Tabata C,Ohta T,Kuribayashi K,Fukuoka K,Nakano T

更新日期：2011-03-01 00:00:00

abstract：:Dermal fibroblasts exposed to low oxygen tension show upregulated synthesis of transforming growth factor-beta 1 (TGF-beta 1), an established stimulatory peptide in the formation of extracellular matrix proteins. In this report, procollagen synthesis was measured in cultures of confluent adult human dermal fibroblasts...

journal_title：Journal of cellular physiology

authors： Falanga V,Martin TA,Takagi H,Kirsner RS,Helfman T,Pardes J,Ochoa MS

更新日期：1993-11-01 00:00:00

abstract：:Sirtuins are a family of enzymes, which govern a number of cellular processes essential for maintaining physiological balance. SIRT6, a nuclear sirtuin, is implicated in the development of metabolic disorders. The role of SIRT6 in regulation of cardiac metabolism is unexplored. Although glucose is not the primary ener...

journal_title：Journal of cellular physiology

authors： Khan D,Sarikhani M,Dasgupta S,Maniyadath B,Pandit AS,Mishra S,Ahamed F,Dubey A,Fathma N,Atreya HS,Kolthur-Seetharam U,Sundaresan NR

更新日期：2018-07-01 00:00:00

abstract：:The fetal and neonatal development of male germ cells (gonocytes) is a poorly understood but crucial process for establishing fertility. In rodents, gonocytes go through two phases of proliferation accompanied by apoptosis and separated by a quiescent period during the end of fetal development. P63 is a member of the ...

journal_title：Journal of cellular physiology

authors： Petre-Lazar B,Livera G,Moreno SG,Trautmann E,Duquenne C,Hanoux V,Habert R,Coffigny H

更新日期：2007-01-01 00:00:00

abstract：:Increasing evidence has demonstrated that abnormal expression of lncRNA is correlated with various malignant tumors, including hepatocellular carcinoma (HCC). Our current study was aimed to investigate the role of LINC00707 in HCC development. We observed that LINC00707 was upregulated in HCC cell lines compared with ...

journal_title：Journal of cellular physiology

authors： Wang J,Luo Z,Yao T,Li W,Pu J

更新日期：2019-05-01 00:00:00

abstract：:The desert hedgehog (Dhh) is crucial for spermatogenesis and Leydig cell differentiation, but little is known regarding its physiological function in cartilage. In this study, Dhh mRNA was abundant in antler chondrocytes, where it advanced cell proliferation concomitant with accelerated transition from the G1 to the S...

journal_title：Journal of cellular physiology

authors： Ma L,Duan CC,Yang ZQ,Ding JL,Liu S,Yue ZP,Guo B

更新日期：2020-09-01 00:00:00

abstract：:The aim of our studies was to identify miRNAs affecting the release of the major ovarian steroid hormones progestagen, androgen and estrogen by human ovarian cells. The effect of transfection of cultured primary ovarian granulosa cells with 80 different gene constructs encoding human pre-miRNAs on release of progester...

journal_title：Journal of cellular physiology

authors： Sirotkin AV,Ovcharenko D,Grossmann R,Lauková M,Mlyncek M

更新日期：2009-05-01 00:00:00

abstract：:Changes in the concentration of intracellular Ca(2+) ([Ca(2+) ]i) trigger and/or regulate principal sperm functions during fertilization, such as motility, capacitation, and the acrosome reaction (AR). Members of the large TRP channel family participate in a variety of Ca(2+) -dependent cell signaling processes. The e...

journal_title：Journal of cellular physiology

authors： Martínez-López P,Treviño CL,de la Vega-Beltrán JL,De Blas G,Monroy E,Beltrán C,Orta G,Gibbs GM,O'Bryan MK,Darszon A

更新日期：2011-06-01 00:00:00

abstract：:Ebp1, an ErbB-3 binding protein, inhibits the proliferation and induces the differentiation of human breast cancer cells. The mechanisms of these effects are unknown. Rb, the product of the retinoblastoma gene, is an important modulator of cell cycle progression and cellular differentiation. We report that Rb is a bin...

journal_title：Journal of cellular physiology

authors： Xia X,Cheng A,Lessor T,Zhang Y,Hamburger AW

更新日期：2001-05-01 00:00:00

abstract：:We have previously shown that Compound 5 (Cpd 5), an inhibitor of protein phosphatase Cdc25A, inhibits Hep3B human hepatoma cell growth. We now show that hepatocyte growth factor (HGF), a hepatocyte growth stimulant, can strongly enhance Cpd 5-induced growth inhibition in Hep3B cells, and this enhancement in cell grow...

journal_title：Journal of cellular physiology

authors： Wang Z,Wang M,Carr BI

更新日期：2005-06-01 00:00:00

abstract：:The growth response of cultured rat intestinal epithelial (RIE-1) cells to epidermal growth factor (EGF) depends on the cell population density. EGF stimulated the proliferation of RIE-1 cells in dense cultures, but inhibited the proliferation of cells growing at low population densities. In contrast, insulin enhanced...

journal_title：Journal of cellular physiology

authors： Blay J,Brown KD

更新日期：1986-12-01 00:00:00

abstract：:Glioblastoma (GB) is the most common cancer in the brain and with an increasing incidence. Despite major advances in the field, there is no curative therapy for GB to date. Many solid tumors, including GB, experienced metabolic reprogramming in order to sustain uncontrolled proliferation, hypoxic conditions, and angio...

journal_title：Journal of cellular physiology

authors： Benedetti E,d'Angelo M,Ammazzalorso A,Gravina GL,Laezza C,Antonosante A,Panella G,Cinque B,Cristiano L,Dhez AC,Astarita C,Galzio R,Cifone MG,Ippoliti R,Amoroso R,Di Cesare E,Giordano A,Cimini A

更新日期：2017-06-01 00:00:00

abstract：:COVID-19, a new disease caused by the 2019-novel coronavirus (SARS-CoV-2), has swept the world and challenged its culture, economy, and health infrastructure. Forced emergence to find an effective vaccine to immunize people has led scientists to design and examine vaccine candidates all over the world. Until a vaccine...

journal_title：Journal of cellular physiology

authors： Rezaei M,Ziai SA,Fakhri S,Pouriran R

更新日期：2020-09-09 00:00:00

abstract：:Tyrosine hydroxylase (TH), catalyzing the conversion of tyrosine into l-DOPA, is the rate-limiting enzyme in dopamine synthesis. Defects in insulin action contribute to alterations of TH expression and/or activity in the brain and insulin increases TH levels in 1-methyl-4-phenylpyridinium (MPP+)-treated neuronal cells...

journal_title：Journal of cellular physiology

authors： Fiory F,Mirra P,Nigro C,Pignalosa FC,Zatterale F,Ulianich L,Prevete N,Formisano P,Beguinot F,Miele C

更新日期：2019-07-01 00:00:00

abstract：:Nidogen/entactin is a Mr = 150,000 glycoprotein which is present within basement membranes in a noncovalent stable complex with laminin. We have studied the effects of nidogen/entactin complexed or not with laminin on attachment, spreading, and functions of adult rat hepatocytes in primary culture. Freshly isolated he...

journal_title：Journal of cellular physiology

authors： Levavasseur F,Mayer U,Guillouzo A,Clement B

更新日期：1994-11-01 00:00:00

abstract：:Retinoic acid inhibits proliferation of hormone-dependent, but not hormone-independent breast cancer cells. Retinoic acid-induced changes in cellular proliferation and differentiation are associated with disturbances in growth factor signaling and frequently with changes in protein kinase C expression. PKC delta, epsi...

journal_title：Journal of cellular physiology

authors： Cho Y,Tighe AP,Talmage DA

更新日期：1997-09-01 00:00:00

abstract：:Erythropoietin (EPO) retards DNA breakdown characteristic of programmed cell death (apoptosis) and promotes survival in erythroid progenitor cells. The mechanism by which EPO inhibits programmed death is unknown. In the well-characterized model of glucocorticoid-treated thymocytes, activation of a Ca2+/Mg(2+)-sensitiv...

journal_title：Journal of cellular physiology

authors： Kelley LL,Koury MJ,Bondurant MC

更新日期：1992-06-01 00:00:00

abstract：:The phytohemagglutinin (PHA)-stimulated human lymphocytes demonstrated trace or no activity (dihydro) folate acid reductase using three methods including a radioassay, but demonstrated ample activity of thymidylate synthetase. This was true regardless of the day of harvest, (first through seventh) of the stimulated ly...

journal_title：Journal of cellular physiology

authors： Haurani FI,Kardinal CG,Biermann WA

更新日期：1978-04-01 00:00:00

abstract：:Mast cells are central regulators of allergic inflammation through production of various chemical mediators and cytokines. Bacterial infection occasionally worsens allergic inflammation. Although the exact mechanism of this phenomenon remains unclear, we have previously reported that LPS stimulates mast cells to produ...

journal_title：Journal of cellular physiology

authors： Chiba N,Masuda A,Yoshikai Y,Matsuguchi T

更新日期：2007-10-01 00:00:00

abstract：:Although the type 1 insulin-like growth factor receptor (IGF-IR) is a potent inhibitor of apoptosis, its C-terminus sequence sends contradictory signals, including a clearly proapoptotic signal. We have synthesized a peptide, peptide 2, having the sequence of the IGF-IR from residue 1282 to residue 1298 (C-terminus of...

journal_title：Journal of cellular physiology

authors： Reiss K,Yumet G,Shan S,Huang Z,Alnemri E,Srinivasula SM,Wang JY,Morrione A,Baserga R

更新日期：1999-10-01 00:00:00

abstract：:Alternative splicing (AS) is critically associated with tumorigenesis and patient's prognosis. Here, we systematically analyzed survival-associated AS signatures in oral squamous cell carcinoma (OSCC) and evaluated their prognostic predictive values. Survival-related AS events were identified by univariate and multiva...

journal_title：Journal of cellular physiology

authors： Zhang S,Wu X,Diao P,Wang C,Wang D,Li S,Wang Y,Cheng J

更新日期：2020-05-01 00:00:00

abstract：:Pur-alpha is an essential protein for postnatal brain development which localizes specifically to dendrites where it plays a role in the translation of neuronal RNA. Mice lacking Pur-alpha display decreased neuronogenesis and impaired neuronal differentiation. Here we examined two Rho GTPases, Rac1 and RhoA, which pla...

journal_title：Journal of cellular physiology

authors： Mishra M,Del Valle L,Otte J,Darbinian N,Gordon J

更新日期：2013-01-01 00:00:00

abstract：:Elevated levels of follistatin-like protein 1 (FSTL1) have been found both in mouse models for human rheumatoid arthritis (RA) and collagen-induced arthritis (CIA). In this study, we elucidated the potential mechanisms by which FSTL1 contributes to the pathogenesis of RA. Fibroblast-like synoviocytes (FLSs) were estab...

journal_title：Journal of cellular physiology

authors： Ni S,Li C,Xu N,Liu X,Wang W,Chen W,Wang Y,van Wijnen AJ

更新日期：2018-01-01 00:00:00

abstract：:Syndecan-1 belongs to a family of transmembrane proteoglycans, acts as a coreceptor for growth factor binding, as well as cell-matrix and cell-cell interactions, and is induced in smooth muscle cells (SMCs) following balloon catheter injury. In this report, we investigated syndecan-1 expression in SMCs in response to ...

journal_title：Journal of cellular physiology

authors： Julien MA,Haller CA,Wang P,Wen J,Chaikof EL

更新日期：2007-04-01 00:00:00

abstract：:Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, is one of the leading causes of death worldwide. Despite the advances in cardiovascular research, there remains a need to further investigate the signaling pathways that mediate CH in order to identify novel therapeut...

journal_title：Journal of cellular physiology

authors： Riaz S,Zeidan A,Mraiche F

更新日期：2017-12-01 00:00:00

abstract：:An association has been proved between high salt consumption and cardiovascular mortality. In vertebrates, the heart is the first functional organ to be formed. However, it is not clear whether high-salt exposure has an adverse impact on cardiogenesis. Here we report high-salt exposure inhibited basement membrane brea...

journal_title：Journal of cellular physiology

authors： Gao LR,Wang G,Zhang J,Li S,Chuai M,Bao Y,Hocher B,Yang X

更新日期：2018-09-01 00:00:00

abstract：:We have previously reported that interferon-alpha (IFNalpha) induces apoptosis and EGF can antagonize this effect in human epidermoid cancer KB cells. Since apoptosis occurs together with cytoskeleton reorganization we have evaluated if IFNalpha and EGF could modulate cell remodeling in our experimental conditions. We...

journal_title：Journal of cellular physiology

authors： Boccellino M,Giuberti G,Quagliuolo L,Marra M,D'Alessandro AM,Fujita H,Giovane A,Abbruzzese A,Caraglia M

更新日期：2004-10-01 00:00:00

abstract：:Oxidized-low density lipoprotein (Ox-LDL) has been shown to play an important role in impaired surfactant metabolism and transforming growth factor-β1 (TGF-β1) is a critical mediator in the pathogenesis of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). In this study, we investigated whether Ox-LDL...

journal_title：Journal of cellular physiology

authors： Guo LL,Chen YJ,Wang T,An J,Wang CN,Shen YC,Yang T,Zhao L,Zuo QN,Zhang XH,Xu D,Wen FQ

更新日期：2012-09-01 00:00:00

abstract：:UDPgalactose inhibits the growth of mouse leukemic L1210 cells. In calf serum supplemented Dulbecco's medium (CS-DMEM), 1.2 mM UDPgalactose (UDPgal) inhibited cell growth by 50% (IC50), and 5 mM UDPgalactose inhibited cell growth by 92%. Other nucleotide sugars as well as galactose, glucose, and galactose-1-phosphate ...

journal_title：Journal of cellular physiology

authors： Klohs WD,Wilson JR,Weiser MM,Frankfurt O,Bernacki RJ

更新日期：1984-04-01 00:00:00

abstract：:The epidermal growth factor (EGF) receptor interacts with structural elements of A431 cells and remains associated with the cytoskeleton following extraction with nonionic detergents. Extraction of cells with 0.15% Triton X-100 resulted in detection of only approximately 40% of the EGF binding sites on the cytoskeleto...

journal_title：Journal of cellular physiology

authors： Roy LM,Gittinger CK,Landreth GE

更新日期：1991-01-01 00:00:00