Enhanced transbilayer mobility of phospholipids in malaria-infected monkey erythrocytes: a spin-label study.

Abstract:

:Using a recently described technique of electron spin resonance spectroscopy, we determined the rate of transbilayer mobility (flip) of the four major simian-erythrocyte phospholipids in the erythrocyte membrane after infection by Plasmodium knowlesi. The development of the malarial parasite induces a very large increase in the flip rate of these phospholipids (mainly during the ring stage and at the beginning of trophozoite maturation). The half flip time fell from 2 and 3 hr in the case of choline phospholipids in healthy erythrocytes to less than 15 min in erythrocytes infected with the last stage of the parasite.

journal_name

J Cell Physiol

authors

Beaumelle BD,Vial HJ,Bienvenüe A

doi

10.1002/jcp.1041350113

subject

Has Abstract

pub_date

1988-04-01 00:00:00

pages

94-100

issue

1

eissn

0021-9541

issn

1097-4652

journal_volume

135

pub_type

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