Delay of M-phase onset by aphidicolin can retain the nuclear localization of zinc and metallothionein in 3T3-L1 fibroblasts.

abstract：:The clinical literature strongly suggests that bone healing in cigarette smokers is impaired. Since cigarette smoke (CS) contains numerous polycyclic aromatic hydrocarbons (PAHs), and since dioxins impair bone formation in vivo via the Aryl Hydrocarbon Receptor (AHR), we investigated the impact of PAH/AHR signaling on...

journal_title：Journal of cellular physiology

authors： Kung MH,Yukata K,O'Keefe RJ,Zuscik MJ

更新日期：2012-03-01 00:00:00

abstract：:Maintenance of intestinal epithelial barrier functions is crucial to prevent systemic contamination by microbes that penetrate from the gut lumen. GTPases of the Rho-family such as RhoA, Rac1, and Cdc42 are known to be critically involved in the regulation of intestinal epithelial barrier functions. However, it is sti...

journal_title：Journal of cellular physiology

authors： Schlegel N,Meir M,Spindler V,Germer CT,Waschke J

更新日期：2011-05-01 00:00:00

abstract：:We have proposed that the transmembrane receptor encoded by the c-Kit protooncogene and its ligand play an important role in regulating the proliferation of blasts cells in acute myeloblastic leukemia (AML). To test this hypothesis, immunobeads were used to separate blasts from three Kit-expression positive cell lines...

journal_title：Journal of cellular physiology

authors： Tohda S,Yang GS,Ashman LK,McCulloch EA,Minden MD

更新日期：1993-02-01 00:00:00

abstract：:Clones of Chinese hamster ovary (CHO) cells were isolated by single-step selection for resistance to killing Concanavalin A (ConA) and certain cellular and membrane properties were examined. The ConA-resistant isolates were only about 2-fold more resistant than wild type cells to the selecting lectin, but exhibited pl...

journal_title：Journal of cellular physiology

authors： Cifone MA,Hynes RO,Baker RM

更新日期：1979-07-01 00:00:00

abstract：:In recent years, research on glioma immunotherapy have grown rapidly. However, the autoimmune-like side effects that are caused by blocking immunological checkpoints hinder their clinical application in gliomas currently. Galectin-9, a ligand for T-cell immunoglobulin mucin 3, has shed a new light on the treatment of ...

journal_title：Journal of cellular physiology

authors： Yuan F,Ming H,Wang Y,Yang Y,Yi L,Li T,Ma H,Tong L,Zhang L,Liu P,Li J,Lin Y,Yu S,Ren B,Yang X

更新日期：2020-05-01 00:00:00

abstract：:Adipogenesis plays a key role in the pathogenesis of obesity. It begins with the commitment of mesenchymal stem cells (MSCs) to the adipocyte lineage, followed by terminal differentiation of preadipocytes to mature adipocytes. A critical, but poorly understood, component of adipogenesis involves proliferation of MSCs ...

journal_title：Journal of cellular physiology

authors： Stewart A,Guan H,Yang K

更新日期：2010-06-01 00:00:00

abstract：:Carbonic anhydrase (CAH) was localized in the mitochondria-rich cells (MRC) of 1-week-old salamander larvae gill epithelium, in both MRC and pavement cells of 6-week-old larvae, and in regenerated stems of previously amputated gills. CAH activity of the MRC was measured quantitatively using a microscope densitometric ...

journal_title：Journal of cellular physiology

authors： Lewinson D,Rosenberg M,Goldenberg S,Warburg MR

更新日期：1987-01-01 00:00:00

abstract：:The human neuroblastoma cell line SK-N-BE, after incubation with 10 microM retinoic acid (RA) or 20 nM phorbol 12-myristate 13-acetate (PMA), underwent biochemical and morphological signs of differentiation within 10-14 days. In parallel, SK-N-BE cells produced significantly higher amounts of nitric oxide (NO) in comp...

journal_title：Journal of cellular physiology

authors： Ghigo D,Priotto C,Migliorino D,Geromin D,Franchino C,Todde R,Costamagna C,Pescarmona G,Bosia A

更新日期：1998-01-01 00:00:00

abstract：:Optical tweezers were used to scan individual Chronic Myelogenous Leukemia cells to determine if the cell death depends on the scanning conditions. Although increasing the scanning frequency or amplitude means greater force applied to the cells, their effects on cell death are not a simple increasing trend, as observe...

journal_title：Journal of cellular physiology

authors： Ng KS,Zhou ZL,Ngan AH

更新日期：2013-10-01 00:00:00

abstract：:Active oxygen species are generated in cells during pathophysiologic conditions such as inflammation and postischemic reperfusion. If oxygen radical scavengers are added before reperfusion, then the magnitude of injury is reduced. We investigated whether free radicals generated following exposure to hypoxia and reoxyg...

journal_title：Journal of cellular physiology

authors： Koong AC,Giaccia AJ,Hahn GM,Saad AH

更新日期：1993-08-01 00:00:00

abstract：:A previously described chondrocyte alkaline phosphatase induction factor (CAP-IF) for chicken epiphyseal growth plate chondrocytes has been purified to SDS-PAGE homogeneity from fetal bovine serum by ammonium sulfate precipitation and by dye-ligand affinity (Affi-Gel Blue and Reactive Green-19 agarose) and hydroxyapat...

journal_title：Journal of cellular physiology

authors： Ishikawa Y,Wu LN,Valhmu WB,Wuthier RE

更新日期：1991-11-01 00:00:00

abstract：:Proteasome inhibitors represent a promising therapy for the treatment of relapsed and/or refractory multiple myeloma, a disease that is concomitant with osteolysis and enhanced osteoclast formation. While blockade of the proteosome pathway has been recently shown to influence osteoclast formation and function, the pre...

journal_title：Journal of cellular physiology

authors： Ang E,Pavlos NJ,Rea SL,Qi M,Chai T,Walsh JP,Ratajczak T,Zheng MH,Xu J

更新日期：2009-08-01 00:00:00

abstract：:Two genes (MAT1A and MAT2A) encode for the essential enzyme methionine adenosyltransferase (MAT). MAT1A is silenced in hepatocellular carcinoma (HCC), and absence of MAT1A leads to spontaneous development of HCC in mice. Previous report correlated promoter methylation to silencing of MAT1A but definitive proof was lac...

journal_title：Journal of cellular physiology

authors： Tomasi ML,Li TW,Li M,Mato JM,Lu SC

更新日期：2012-04-01 00:00:00

abstract：:Pain can vary over the estrous cycle as a result of changes in estradiol concentration but the mechanism causing this variation is unclear. Because the thalamus is important in pain control, gene expression in the lateral thalamus (ventral posteromedial, ventral posterolateral, reticular thalamic nuclei) was screened ...

journal_title：Journal of cellular physiology

authors： Umorin M,Stinson C,Bellinger LL,Kramer PR

更新日期：2016-05-01 00:00:00

abstract：:We have examined the ability of epidermal growth factor (EGF) to regulate prostacyclin production by cultured A10 smooth muscle cells. EGF by itself had no effect on prostacyclin production, but it augmented the response to arg8-vasopressin. An AGF stimulation of prostacyclin production was also observed in the presen...

journal_title：Journal of cellular physiology

authors： Blay J,Hollenberg MD

更新日期：1989-06-01 00:00:00

abstract：:A sialoglycopeptide (SGP), isolated and purified from bovine cerebral cortex cells, was studied in regard to early signal transduction events associated with the cell cycle. Previously shown to be a potent antagonist to a variety of mitogens, the SGP abrogated the ability of 12-O-tetradecanoylphorbol-13 acetate (TPA) ...

journal_title：Journal of cellular physiology

authors： Toole-Simms WE,Loder DK,Fattaey HK,Johnson TC

更新日期：1991-05-01 00:00:00

abstract：:We have examined nucleoside transport (NT) in a cell line derived from primary day 7 murine bone marrow macrophages (S1 macrophages) in response to the macrophage growth factor, colony-stimulating factor 1 (CSF-1). Adenosine and uridine transport in quiescent S1 macrophages occurred primarily by two facilitated diffus...

journal_title：Journal of cellular physiology

authors： Meckling-Gill KA,Guilbert L,Cass CE

更新日期：1993-06-01 00:00:00

abstract：:At the end of December 2019, a novel acute respiratory syndrome coronavirus 2 (SARS-CoV2) appeared as the third unheard of outbreak of human coronavirus infection in the 21st century. First, in Wuhan, China, the novel SARS-CoV2 was named by the World Health Organization (WHO), as 2019-nCOV (COVID-19), and spread extre...

journal_title：Journal of cellular physiology

authors： Tahmasebi S,Khosh E,Esmaeilzadeh A

更新日期：2020-12-01 00:00:00

abstract：:We have analyzed the functional and morphological effects of corticosteroid hormones in a SV40-transformed rabbit cortical-ascending-limb (CAL) cell line (RC.SV2, Vandewalle et al., 1989) having mineralocorticoid (MR) and glucocorticoid (GR) receptors (Rafestin-Oblin et al., 1993). Both aldosterone and dexamethasone (...

journal_title：Journal of cellular physiology

authors： Vandewalle A,Rafestin-Oblin ME,Hagege J,Géniteau-Legendre M,Cassingéna R,Ronco PM

更新日期：1993-08-01 00:00:00

abstract：:The human polyomavirus, JC virus (JCV), provides an excellent model system to investigate the reciprocal interaction of the immune and nervous systems. Infection with JCV occurs during childhood and the virus remains in the latent state with no apparent clinical symptoms. However, under immunosuppressed conditions, th...

journal_title：Journal of cellular physiology

authors： Sweet TM,Del Valle L,Khalili K

更新日期：2002-06-01 00:00:00

abstract：:An artificial wound in a confluent monolayer of human keratinocyte HaCaT cells or mouse embryo fibroblast Swiss NIH 3T3 cells was used to analyze the effects of the nitric oxide (NO) chemical donor, S-nitroso-N-acetylpenicillamine (SNAP). SNAP exposure promoted an enhanced rate of wound closure and accelerated motilit...

journal_title：Journal of cellular physiology

authors： La Torre C,Cinque B,Lombardi F,Miconi G,Palumbo P,Evtoski Z,Placidi G,Fanini D,Cimini AM,Benedetti E,Giuliani M,Cifone MG

更新日期：2016-10-01 00:00:00

abstract：:Increasing evidence has demonstrated that abnormal expression of lncRNA is correlated with various malignant tumors, including hepatocellular carcinoma (HCC). Our current study was aimed to investigate the role of LINC00707 in HCC development. We observed that LINC00707 was upregulated in HCC cell lines compared with ...

journal_title：Journal of cellular physiology

authors： Wang J,Luo Z,Yao T,Li W,Pu J

更新日期：2019-05-01 00:00:00

abstract：:Indirect evidence for the presence of a growth inhibitor in normal human fibroblasts has been obtained previously; the inhibitory activity has been found associated with crude cell extracts, but the molecule responsible for the growth inhibition has never been isolated. We have isolated a glycopeptide fraction from hu...

journal_title：Journal of cellular physiology

authors： Macieira-Coelho A,Söderberg A

更新日期：1993-01-01 00:00:00

abstract：:It was the goal of this study to determine whether during long-term quiescence WI-38 cells gradually lose labile components which then need to be resynthesized before a stimulated cell can progress through G-1 and enter S. The metabolic and molecular status of WI-38 cells was systematically analyzed as they entered an...

journal_title：Journal of cellular physiology

authors： Owen TA,Carter R,Whitman MM,Soprano DR,Soprano KJ

更新日期：1990-01-01 00:00:00

abstract：:Cell division in fertilized sea urchin eggs was reversibly inhibited when the ketoaldehyde phenyl glyoxal (PG) at a concentration of 0.1 mM was added to eggs for ten minutes prior to the formation of the mitotic spindle. We investigated whether inhibition of mitosis was due to PG binding to the cell surface (as previo...

journal_title：Journal of cellular physiology

authors： Amy CM,Rebhun LI

更新日期：1979-07-01 00:00:00

abstract：:32D cells are murine myeloid cells that grow indefinitely in Interleukin-3 (IL-3). In these cells, the type 1 insulin-like growth factor (IGF-I) and granulocytic-colony stimulating factor (G-CSF) induce differentiation to granulocytes. 32D cells do not express insulin receptor substrate-1 (IRS-1) or IRS-2, docking pro...

journal_title：Journal of cellular physiology

authors： Shi B,Prisco M,Calin G,Liu CG,Russo G,Giordano A,Baserga R

更新日期：2006-06-01 00:00:00

abstract：:At 37 degrees C, undifferentiated murine teratocarcinoma cells (PCC4) are resistant to infection with SV40 and Polyoma virus. When infection is carried out at 31 degrees C, these cells become fully susceptible to a variety of polyoma virus strains, including wt, ts-a, and hr-t; they also display an increased susceptib...

journal_title：Journal of cellular physiology

authors： Dandolo L,Vasseur M,Kress C,Aghion J,Blangy D

更新日期：1980-10-01 00:00:00

abstract：:DEAH box protein DHX33 has been found to be necessary for cell proliferation and early development of multicellular organisms. It plays diverse roles in regulating gene transcription, ribosome RNA synthesis, and protein translation. Dysregulation of DHX33 has been observed in various human cancers. In this study, we i...

journal_title：Journal of cellular physiology

authors： Su D,Yuan B,Su C,Zhang Y

更新日期：2019-01-26 00:00:00

abstract：:We have modified a method (Gilles et al: Anal. Biochem., 159:109-113, 1986) for measuring cell number, that is based on the binding of crystal violet to cell nuclei and used it to assay effects of various glycosaminoglycans on growth of human lung fibroblasts. The procedure was modified by growing cells in microcultur...

journal_title：Journal of cellular physiology

authors： Westergren-Thorsson G,Onnervik PO,Fransson LA,Malmström A

更新日期：1991-06-01 00:00:00

abstract：:The components of the insulin-like growth factor (IGF) axis and their roles in regulating proliferation and differentiation of the human colon adenocarcinoma cell line, Caco-2, have been investigated. Caco-2 cells proliferated in serum-free medium at 75% the rate observed in medium containing 10% fetal bovine serum. I...

journal_title：Journal of cellular physiology

authors： Park JH,Corkins MR,Vanderhoof JA,Caruso NM,Hrbek MJ,Schaffer BS,Slentz DH,McCusker RH,MacDonald RG

更新日期：1996-02-01 00:00:00