Inhibitory effects of acetylcholine on aggressive-defense reaction induced by electrical stimulation of the hypothalamus in cats.

Abstract:

:The effects of ventral amygdalofugal pathways (VAF) or stria terminalis (ST) on the hypothalamic aggressive-defense (rage) reaction were examined in fifteen cats. After bilateral electrolytic lesions of the VAF or ST, 0.5 pmol of acetylcholine (ACh) was injected into the VMH and electrical stimulation was applied. The changes in the threshold for range reaction were compared in the non-lesioned, VAF-lesioned and ST-lesioned group. Both VAF-lesioned and non-lesioned cats showed a similar degree of significant elevation in the threshold for rage at 5 min after injection, while ST-lesioned group had no significant elevation. These results suggest that the ST is concerned with the elevation of threshold for rage due to ACh injection.

journal_name

Brain Res Bull

journal_title

Brain research bulletin

authors

Kono R,Tashiro N,Nakao H

doi

10.1016/0361-9230(86)90178-4

subject

Has Abstract

pub_date

1986-04-01 00:00:00

pages

491-5

issue

4

eissn

0361-9230

issn

1873-2747

pii

0361-9230(86)90178-4

journal_volume

16

pub_type

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