A phospholipase inhibitor modifies the pulmonary damage associated with peritonitis in rabbits.

abstract：OBJECTIVE:Endotracheal suctioning can cause alveolar collapse and impede ventilation. One reason is the gas flow through a single-lumen endotracheal tube (ETT) provoking a gradient between airway opening and tracheal (P(tr)) pressures. Separately extending the patient tubing limbs of a suitable ventilator into the trac...

journal_title：Intensive care medicine

authors： Reissmann H,Böhm SH,Suárez-Sipmann F,Tusman G,Buschmann C,Maisch S,Pesch T,Thamm O,Plümers C,Schulte am Esch J,Hedenstierna G

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Acute hypoxemic respiratory failure (AHRF) is a common reason for emergency pediatric intensive care. An objective assessment of disease severity from acute physiological parameters would be of value in clinical practice and in the design of clinical trials. We hypothesised that there was a difference in the ...

journal_title：Intensive care medicine

authors： Peters MJ,Tasker RC,Kiff KM,Yates R,Hatch DJ

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:Bioactive NO carriers in circulating blood formed during NO inhalation selectively distribute blood flow to areas in need, and may thus improve collateral perfusion to the area-at-risk in acute myocardial infarction (AMI). Here, we tested the hypothesis that NO inhalation during the ischemic phase of AMI may im...

journal_title：Intensive care medicine

authors： Neye N,Enigk F,Shiva S,Habazettl H,Plesnila N,Kuppe H,Gladwin MT,Kuebler WM

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Transcapillary heat transfer after injections of cold saline into the right atrium generates bronchial thermodilution curves resembling those observed in the aorta. Under the assumption that no indicator is lost or gained within the pulmonary capillary bed and changes in blood temperature are instantaneously ...

journal_title：Intensive care medicine

authors： Loer SA,Wietasch JK,Scheeren TW

更新日期：1999-02-01 00:00:00

abstract：PURPOSE:Intensive care unit survivors suffer from prolonged impairment, reduced quality of life, and higher mortality rates after discharge compared to the general population. Socioeconomic status may play a partial but important role in mortality and recovery. Therefore, the detection of factors that are responsible f...

journal_title：Intensive care medicine

authors： Bastian K,Hollinger A,Mebazaa A,Azoulay E,Féliot E,Chevreul K,Fournier MC,Guidet B,Michel M,Montravers P,Pili-Floury S,Sonneville R,Siegemund M,Gayat E,FROG-ICU Study Investigators.

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Pseudomonas aeruginosa-induced lung injury is characterized not only by the alteration in lung fluid movement but also by apoptosis of lung epithelial and endothelial cells. We studied whether inhibition of apoptosis using a broad spectrum caspase inhibitor, benzyloxycarbonyl-Val-Ala-Asp fluoromethylketone (Z...

journal_title：Intensive care medicine

authors： Le Berre R,Faure K,Fauvel H,Viget NB,Ader F,Prangère T,Thomas AM,Leroy X,Pittet JF,Marchetti P,Guery BP

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To define the changes in middle cerebral artery flow velocity (Vmca) and the electroencephalogram (EEG) during rapid reduction in arterial carbon dioxide (PCO2) from acute hypercapnia. DESIGN. Human volunteer study. SETTING:University-affiliated hospital experimental laboratory. PARTICIPANTS:Nine healthy vo...

journal_title：Intensive care medicine

authors： Halpern P,Neufeld MY,Sade K,Silbiger A,Szold O,Bornstein NM,Sorkine P

更新日期：2003-10-01 00:00:00

abstract：:Malaria remains today one of the major health problems in the tropics with increased morbidity and mortality. The most serious complications are caused by Plasmodium falciparum, which, in contrast to the benign malarias, may progress to a life-threatening multi-system disease. Our case concerns a young woman in the 14...

journal_title：Intensive care medicine

authors： Gregorakos L,Sakayianni K,Hroni D,Harizopoulou V,Georgiadou F,Adamidou M

更新日期：1999-07-01 00:00:00

abstract：:A young woman with long-standing systemic lupus erythematosus and rheumatic fever presented with deteriorating renal function. She had severe gastritis treated with cimetidine and received methylprednisolone when her blood cultures were repeatedly negative. She developed spontaneous bruising and bleeding from venepunc...

journal_title：Intensive care medicine

authors： Bloxham CA,Carr S,Ryan DW,Kesteven PJ,Bexton RS,Griffiths ID,Richards J

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To compare the efficiency of non-invasive positive pressure ventilation (NPPV) in decompensated patients with either chronic obstructive pulmonary disease (COPD) or chronic restrictive pulmonary disease. DESIGN:Retrospective study. SETTING:A 17-bed intensive care unit in a university teaching hospital. SET...

journal_title：Intensive care medicine

authors： Robino C,Faisy C,Diehl JL,Rezgui N,Labrousse J,Guerot E

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:Measurement of functional residual capacity (FRC) during controlled and especially during assisted ventilation remains a challenge in the physiological evaluation of ventilated patients. To validate a bag-in-box closed helium dilution technique allowing measurements both during pressure-controlled (PCV) and p...

journal_title：Intensive care medicine

authors： Di Marco F,Rota Sperti L,Milan B,Stucchi R,Centanni S,Brochard L,Fumagalli R

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:Clinical examination is often the first step to diagnose shock and estimate cardiac index. In the Simple Intensive Care Studies-I, we assessed the association and diagnostic performance of clinical signs for estimation of cardiac index in critically ill patients. METHODS:In this prospective, single-centre coho...

journal_title：Intensive care medicine

authors： Hiemstra B,Koster G,Wiersema R,Hummel YM,van der Harst P,Snieder H,Eck RJ,Kaufmann T,Scheeren TWL,Perner A,Wetterslev J,de Smet AMGA,Keus F,van der Horst ICC,SICS Study Group.

更新日期：2019-02-01 00:00:00

abstract：:The Editor-in-Chief has retracted this article [1] because a number of studies included in this review [2, 3, 4] (originally cited as references 98, 128, 129) have since been retracted. Consequently, this has rendered the content of the review unreliable. ...

journal_title：Intensive care medicine

authors： Editorial Office of Intensive Care Medicine.

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To evaluate clinical and microbiologic characteristics, modalities of treatment and outcome of patients with cervical necrotizing fasciitis admitted to our institution. DESIGN:Retrospective clinical investigation. PATIENTS AND METHODS:We reviewed the charts of 20 consecutive patients hospitalized in our Int...

journal_title：Intensive care medicine

authors： Mohammedi I,Ceruse P,Duperret S,Vedrinne J,Boulétreau P

更新日期：1999-08-01 00:00:00

abstract：:The effect of plasma exchange (PE) was evaluated in 4 patients with rhabdomyolysis. A single 21 PE produced a transient fall of creatinine phosphokinase and did not prevent renal failure. Theoretically PE would need to be performed very frequently to remove toxins in appropriate amounts. Since renal failure in myoglob...

journal_title：Intensive care medicine

authors： Cornelissen JJ,Haanstra W,Haarman HJ,Derksen RH

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:Gastrointestinal motility can be impaired by serious illness or medications, compromising enteral feeding in critical care patients. We compared small bowel transit time and morphology in neurosurgical critical care (ICU) patients with those in healthy subjects. METHODS:We evaluated small intestinal transit ti...

journal_title：Intensive care medicine

authors： Rauch S,Krueger K,Turan A,Roewer N,Sessler DI

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:The study was undertaken to determine if critically ill patients under mechanical ventilation could reactivate latent cytomegalovirus (CMV) in either lung or blood. DESIGN:Prospective study in critically ill patients was performed in a multidisciplinary intensive care unit in a university hospital. PATIENTS...

journal_title：Intensive care medicine

authors： Stéphan F,Méharzi D,Ricci S,Fajac A,Clergue F,Bernaudin JF

更新日期：1996-11-01 00:00:00

abstract：PURPOSE:Frail patients are known to experience poor outcomes. Nevertheless, we know less about how frailty manifests itself in patients' physiology during critical illness and how it affects resource use in intensive care units (ICU). We aimed to assess the association of frailty with short-term outcomes and organ supp...

journal_title：Intensive care medicine

authors： Zampieri FG,Iwashyna TJ,Viglianti EM,Taniguchi LU,Viana WN,Costa R,Corrêa TD,Moreira CEN,Maia MO,Moralez GM,Lisboa T,Ferez MA,Freitas CEF,de Carvalho CB,Mazza BF,Lima MFA,Ramos GV,Silva AR,Bozza FA,Salluh JIF,Soar

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:To test the hypothesis that RNA editing is altered in pediatric patients with cyanotic congenital heart disease (CHD) and to determine whether A-to-I RNA editing is associated with the postoperative course following cardiac surgery. Cyanotic CHD is associated with a unique pathophysiology caused by chronic hypo...

journal_title：Intensive care medicine

authors： Borik S,Simon AJ,Nevo-Caspi Y,Mishali D,Amariglio N,Rechavi G,Paret G

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:The efficacy of noninvasive continuous positive airway pressure (CPAP) to improve outcomes in severe hypoxemic acute respiratory failure (hARF) due to pneumonia has not been clearly established. The aim of this study was to compare CPAP vs. oxygen therapy to reduce the risk of meeting criteria for endotracheal ...

journal_title：Intensive care medicine

authors： Brambilla AM,Aliberti S,Prina E,Nicoli F,Del Forno M,Nava S,Ferrari G,Corradi F,Pelosi P,Bignamini A,Tarsia P,Cosentini R

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To analyze the actual cost of pediatric intensive care and its different components, particularly the differences between various patient groups, with special reference to the variable cost and the elements included in it. DESIGN:Prospective, observational study. SETTING:Multidisciplinary 12-bed pediatric i...

journal_title：Intensive care medicine

authors： García S,Ruza F,Alvarado F,Madero R,Delgado MA,Dorao P,Frias M

更新日期：1997-02-01 00:00:00

abstract：:The endothelium is a highly dynamic cell layer that is involved in a multitude of physiological functions, including the control of vascular tone, the movement of cells and nutrients, the maintenance of blood fluidity and the growth of new vessels. During severe sepsis, the endothelium becomes proadhesive, procoagulan...

journal_title：Intensive care medicine

authors： Ait-Oufella H,Maury E,Lehoux S,Guidet B,Offenstadt G

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To assess the effect of partial liquid ventilation with perfluorocarbons on hemodynamics and gas exchange in large pigs with induced acute lung injury (ALI). DESIGN:Randomized, prospective, double-control, experimental study. Experimental intensive care unit of a university. MATERIALS:Eighteen large pigs (5...

journal_title：Intensive care medicine

authors： Houmes RJ,Verbrugge SJ,Hendrik ER,Lachmann B

更新日期：1995-12-01 00:00:00

abstract：PURPOSE:Neurologic and endothelial injury biomarkers are associated with prolonged delirium during critical illness and may reflect injury pathways that lead to poor long-term outcomes. We hypothesized that blood-brain barrier (BBB), neuronal, and endothelial injury biomarkers measured during critical illness are assoc...

journal_title：Intensive care medicine

authors： Hughes CG,Patel MB,Brummel NE,Thompson JL,McNeil JB,Pandharipande PP,Jackson JC,Chandrasekhar R,Ware LB,Ely EW,Girard TD

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To report the first case of ARDS in children treated with nitric oxide (NO) inhalation. METHODS:A 13-months infant presented with BPD and severe hypoxemia related to RSV infection and ARDS. Inhaled NO was delivered in the ventilatory circuit of a continuous flow ventilator (Babylog 8000, Dräger) in a concent...

journal_title：Intensive care medicine

authors： Leclerc F,Riou Y,Martinot A,Storme L,Hue V,Flurin V,Deschildre A,Sadik A

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence, risk factors, and outcomes of critical illness neuromuscular abnormalities (CINMA). DESIGN:Systematic review. DATA SOURCES AND STUDY SELECTION:MEDLINE, EMBASE, CINAHL, and the Cochrane Library were searched for reports on adult ICU patients who were evaluated for CINMA clinicall...

journal_title：Intensive care medicine

authors： Stevens RD,Dowdy DW,Michaels RK,Mendez-Tellez PA,Pronovost PJ,Needham DM

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To demonstrate bleeding complications encountered in patients after cardiac surgery on continuous venovenous haemofiltration (CVVH) treated with continuous versus intermittent r-hirudin for heparin-induced thrombocytopenia (HIT) type II. DESIGN:Case description. SETTING:Cardiothoracic intensive care unit at...

journal_title：Intensive care medicine

authors： Kern H,Ziemer S,Kox WJ

更新日期：1999-11-01 00:00:00

abstract：:A cardiorespiratory monitoring system allows the measurement of FAECO2 and FECO2 in the expired air of the patient at the mouth (endtidal CO2) and in a mixing box. From these parameters, combined with the measured PACO2, the alveolo-expired (DuA = PECO2/PAECO2) and alveolar-arterial (Dua = PAECO2/PACO2) ductances whic...

journal_title：Intensive care medicine

authors： Polu JM,Duvivier C,Sadoul P

更新日期：1980-08-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis whether PMN-Elastase in bronchoalveolar lavage fluid (BALF) could reflect neutrophil activity in the lower respiratory tract. DESIGN:Prospectively, morphologic findings of acute and chronic inflammation in the transbronchial lung biopsy specimens were compared with the numbers of neutr...

journal_title：Intensive care medicine

authors： Lengas A,Poletti V,Pacifico L,di Domizio C,Patelli M,Spiga L

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:To compare the effects of a cerebral perfusion pressure (CPP) intervention achieved with dopamine and norepinephrine after severe head injury. DESIGN:Prospective, controlled, trial. SETTING:Neurosciences critical care unit. PATIENTS:Eleven patients with a head injury, requiring dopamine or norepinephrine i...

journal_title：Intensive care medicine

authors： Johnston AJ,Steiner LA,Chatfield DA,Coles JP,Hutchinson PJ,Al-Rawi PG,Menon DK,Gupta AK

更新日期：2004-05-01 00:00:00