Influenza vaccine: the effects of the 1986/1987 viral strains.

abstract：OBJECTIVES:The objective of this study was to analyze the characteristics and costs of exogenous endoscopy-related infections, pseudo-infections, and toxic reactions in the US. METHODS:A systematic review of the scientific literature published between 1966 and 2005 was conducted in Medline. Data collection was based o...

journal_title：Current medical research and opinion

authors： Seoane-Vazquez E,Rodriguez-Monguio R,Visaria J,Carlson A

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Adequate bowel preparation prior to colonic diagnostic procedures is essential to ensure adequate visualisation. SCOPE:This consensus aims to provide guidance as to the appropriate use of bowel preparation for a range of defined clinical circumstances. A consensus group from across Europe was convened and m...

journal_title：Current medical research and opinion

authors： Mathus-Vliegen E,Pellisé M,Heresbach D,Fischbach W,Dixon T,Belsey J,Parente F,Rio-Tinto R,Brown A,Toth E,Crosta C,Layer P,Epstein O,Boustiere C

更新日期：2013-08-01 00:00:00

abstract：:Studies in several populations have indicated that genetic variation at the apolipoprotein E (apoE) structural locus influences the risk of coronary artery disease (CAD) and myocardial infarction (MI). This study aimed at investigating whether apoE polymorphism has an allelic and/or genotypic impact on the risk of MI ...

journal_title：Current medical research and opinion

authors： Kolovou G,Yiannakouris N,Hatzivassiliou M,Malakos J,Daskalova D,Hatzigeorgiou G,Cariolou MA,Cokkinos DV

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Neurosurgery often requires skull immobilization with a Mayfield clamp, which often causes brief intense nociceptive stimulation, hypertension and tachycardia. Blunting this response may help prevent increased intracranial pressure, cerebral aneurysm or vascular malformation rupture, and/or myocardial stress....

journal_title：Current medical research and opinion

authors： Berger M,Philips-Bute B,Guercio J,Hopkins TJ,James ML,Borel CO,Warner DS,McDonagh DL

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:Tamoxifen, used in breast cancer treatment, may induce hepatic steatosis. It has been suggested that leptin, which has a relationship with body fat stores, may be involved in the pathogenesis of hepatic steatosis. In this study, we compared serum leptin levels in tamoxifen-treated patients with and without hepa...

journal_title：Current medical research and opinion

authors： Günel N,Coşkun U,Toruner FB,Sancak B,Yilmaz E,Cengiz O,Elbeg S,Uner A,Ozkan S

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To estimate the costs and consequences of using pamidronate compared to zoledronic acid in the prophylactic management of skeletal morbidity among breast cancer patients in the UK. DESIGN AND SETTING:This was a modelling study performed from the perspective of the UK's National Health Service (NHS). METHODS...

journal_title：Current medical research and opinion

authors： Guest JF,Clegg JP,Davie AM,McCloskey E

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVES:We conducted an adjusted comparison of progression-free survival (PFS) and overall survival (OS) for daratumumab monotherapy versus standard of care, as observed in a real-world historical cohort of heavily pretreated multiple myeloma patients from Czech Republic. METHODS:Using longitudinal chart data from ...

journal_title：Current medical research and opinion

authors： Jelínek T,Maisnar V,Pour L,Špička I,Minařík J,Gregora E,Kessler P,Sýkora M,Fraňková H,Adamová D,Wróbel M,Mikula P,Jarkovský J,Diels J,Gatopoulou X,Veselá Š,Besson H,Brožová L,Ito T,Hájek R

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Based on the clear neuroanatomical delineation of many neuropathic pain (NP) symptoms, a simple tool for performing a short structured clinical encounter based on the IASP diagnostic criteria was developed to identify NP. This study evaluated its accuracy and usefulness. METHODS:A case-control study was perf...

journal_title：Current medical research and opinion

authors： Mayoral V,Pérez-Hernández C,Muro I,Leal A,Villoria J,Esquivias A

更新日期：2018-08-01 00:00:00

abstract：:Four hundred and twenty-seven hypertensive patients in the United Kingdom have so far been admitted to two on-going open multicentre trials, and have been treated with acebutolol for periods ranging from 1 to 6 months. Oral dosages were within the range of 100 mg to 1200 mg/day in divided doses and were increased or d...

journal_title：Current medical research and opinion

authors： Ashton WL

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:A proactive, multifactorial intervention strategy incorporating single-pill amlodipine/atorvastatin (SPAA) (5-10/10 mg up-titrated to 5-10/20 mg, where approved) is more effective than physician's usual care (UC) for reducing calculated 10 year coronary heart disease (CHD) risk, in patients with hypertension ...

journal_title：Current medical research and opinion

authors： Hradec J,Zamorano J,Sutradhar S

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:Epidemiological data support an association between age-related macular degeneration (AMD) and cataract surgery that may be attributed to post-operative blue light exposure. By limiting the retina's blue light exposure, new blue-light filtering intraocular lenses (BLF IOLs) have the potential to reduce the d...

journal_title：Current medical research and opinion

authors： Reddy P,Gao X,Barnes R,Fairchild C,Boci K,Waycaster C,Pashos C

更新日期：2006-07-01 00:00:00

abstract：:This paper represents a review, by experts, of current opinion and information on intermittent claudication (IC) and the role that cilostazol plays in its treatment. IC is a common and debilitating condition that has a significant adverse impact on health-related quality of life (HR-QoL). It is currently under-recogni...

journal_title：Current medical research and opinion

authors： Barnett AH,Bradbury AW,Brittenden J,Crichton B,Donnelly R,Homer-Vanniasinkam S,Mikhailidis DP,Stansby G

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:It is unclear how well different outcome measures in randomized controlled trials (RCTs) perform in predicting real-world cancer survival. We assess the ability of RCT overall survival (OS) and surrogate endpoints - progression-free survival (PFS) and time to progression (TTP) - to predict real-world OS acros...

journal_title：Current medical research and opinion

authors： Shafrin J,Brookmeyer R,Peneva D,Park J,Zhang J,Figlin RA,Lakdawalla DN

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the efficacy and safety of doses of fentanyl buccal tablet (FBT) proportional to doses of opioids used for background analgesia versus dose titration starting with the minimal dose for the management of breakthrough cancer pain (BTcP). METHODS:A total of 82 cancer patien...

journal_title：Current medical research and opinion

authors： Mercadante S,Gatti A,Porzio G,Lo Presti C,Aielli F,Adile C,Casuccio A

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To analyze the construct validity of the EQ-5D in patients with acute coronary syndromes (ACS). METHODS:All ACS-diagnosed patients discharged from a university-affiliated hospital during a 3-year period were mailed a questionnaire that included the EQ-5D and the SF-8. The EQ-5D includes a visual analogue sca...

journal_title：Current medical research and opinion

authors： Ellis JJ,Eagle KA,Kline-Rogers EM,Erickson SR

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Resistance to endocrine treatment generally occurs over time, especially in the metastatic stage. In this paper, we aimed to review the mechanisms of cyclin-dependent kinase (CDK) 4/6 inhibition and clinical usage of new agents in the light of recent literature updates. SCOPE:A literature search was carried...

journal_title：Current medical research and opinion

authors： Bilgin B,Sendur MAN,Şener Dede D,Akıncı MB,Yalçın B

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:We evaluated the clinical efficacy of sacubitril/valsartan in a group of ambulatory patients with heart failure (HF) with reduced ejection fraction (HFrEF) referred to our HF clinic. METHODS:Patients (n = 29; 72% males; mean age 76 years) with HFrEF in New York Heart Association (NYHA) classes II-III were in...

journal_title：Current medical research and opinion

authors： Cosentino ER,Degli Esposti D,Miceli R,Bentivenga C,Landolfo M,Fg Cicero A,Berardi E,Spinardi L,Magri G,Dugato V,Borghi C

更新日期：2019-03-01 00:00:00

abstract：:Acetyl-L-carnitine (ALC) is a compound acting as an intracellular carrier of acetyl groups across inner mitochondrial membranes. It also appears to have neuroprotective properties and it has recently been shown to reduce attention deficits in patients with Alzheimer's disease (AD) after long-term treatment. We perform...

journal_title：Current medical research and opinion

authors： Bianchetti A,Rozzini R,Trabucchi M

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Alternaria alternata (AA) sensitisation is a common cause of respiratory allergies such as rhinitis and asthma. So far there are no controlled double-blind trials evaluating the efficacy and safety of specific sublingual immunotherapy (SLIT) in AA allergies. OBJECTIVE:To evaluate the efficacy of SLIT treatm...

journal_title：Current medical research and opinion

authors： Pozzan M,Milani M

更新日期：2010-12-01 00:00:00

abstract：:The use of steroid compounds formulated in oil for depot injection can be associated with acute pulmonary reactions characterized primarily by cough, but sometimes with other associated symptoms. The pathophysiology of these reactions remains unclear, although they are reported in the literature as 'POMEs' or pulmonar...

journal_title：Current medical research and opinion

authors： Meyer RJ,Mann M

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Niacin is currently the most effective approved agent for raising high-density lipoprotein cholesterol. However, niacin-induced cutaneous flushing (redness, warmth, tingling and/or itching) significantly limits patient acceptance. To further characterize flushing, a patient-reported Flushing Symptom Question...

journal_title：Current medical research and opinion

authors： Norquist JM,Watson DJ,Yu Q,Paolini JF,McQuarrie K,Santanello NC

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Healthcare organizations must evaluate the cost effectiveness of the alternative therapies that are available to treat anemia and improve quality of life (QoL) of patients with cancer, that is, erythropoietic protein therapy and blood transfusion. METHODS:Pharmacoeconomic studies that evaluated the cost of ...

journal_title：Current medical research and opinion

authors： Cornes P,Coiffier B,Zambrowski JJ

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:We examined patterns of weight change among patients treated with pregabalin for up to 1 year. METHODS:Patients with ≥1 pre-treatment weight measurement, ≥2 measurements in Period 1 (day 2-56), and ≥2 during Period 2 (day 57-356) were identified from pooled data of 106 studies including 43,525 patients. Seve...

journal_title：Current medical research and opinion

authors： Cabrera J,Emir B,Dills D,Murphy TK,Whalen E,Clair A

更新日期：2012-06-01 00:00:00

abstract：:Faecal blood loss arising from tenoxicam at a dose of 20 mg/day was compared to that arising from piroxicam at a dose of 20 mg/day in a double-blind, parallel comparative study in 12 healthy male volunteers. Faecal blood loss was measured for a 1-week run-in on placebo, during 4 weeks of treatment and for a 2-week pos...

journal_title：Current medical research and opinion

authors： Bird HA,Hill J,Haw WM,Dixon JS,Harris PA,Wright V

更新日期：1985-01-01 00:00:00

abstract：AIMS:Disease management programs (DMP) for diabetes mellitus (DM) or coronary heart disease (CHD) address the treatment of lipid disorders. The current registry aimed to compare drug utilization, lipid lowering effects and further outcomes of outpatients at high cardiovascular risk in DMP for DM or CHD compared to pati...

journal_title：Current medical research and opinion

authors： Gitt AK,Sonntag F,Jannowitz C,Weizel A,Karmann B,Schaefer JR,Pittrow D,Hildemann SK

更新日期：2016-01-01 00:00:00

abstract：:One hundred and eight patients who had been taking phenytoin for a year or more, either alone or in combination with other drugs, were examined for gum hypertrophy by three observers independently. Approximately 90% of the patients showed either mild or no gum hypertrophy and severe swelling occurred in only 1%. The o...

journal_title：Current medical research and opinion

authors： Grant RH,Parsonage MJ,Barot MH

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:In order to reduce individual cardiovascular risk, many patients require life-long lipid-lowering therapy, often as a drug combination approach. We aimed to describe the usage pattern, effectiveness and tolerability of long-term treatment with lipid-lowering agents, with particular focus on an oral combinati...

journal_title：Current medical research and opinion

authors： Hildemann SK,Barho C,Karmann B,Darius H,Bode C

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:In a 4-week, double-blind, placebo-controlled study, the attention-promoting agent modafinil improved symptoms of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents and was well tolerated. To assess the continued efficacy of modafinil and obtain additional safety data, an 8-week, open...

journal_title：Current medical research and opinion

authors： Boellner SW,Earl CQ,Arora S

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Eribulin mesylate (eribulin) is indicated for patients with metastatic breast cancer (MBC) who have previously received at least two chemotherapies in the US and for patients with locally advanced breast cancer (LABC) or MBC who have progressed after at least one chemotherapy in the European Union (EU). In b...

journal_title：Current medical research and opinion

authors： Chabot I,Zhao Q,Su Y

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Low back pain in general and specifically chronic low back pain forms a major burden for the patient and society. Recently studies demonstrated that up to 65% of patients evolve to chronic pain as opposed to the previously accepted 8%. As low back pain patients present first with their general practitioner, ...

journal_title：Current medical research and opinion

authors： Itz C,Huygen F,Kleef MV

更新日期：2016-11-01 00:00:00