Validation of a questionnaire to assess niacin-induced cutaneous flushing.

abstract：OBJECTIVE:To compare the efficacy of intranasal fentanyl spray (INFS), oral transmucosal fentanyl citrate (OTFC), fentanyl buccal tablet (FBT) and oral morphine (OM) for the treatment of breakthrough cancer pain (BTCP). METHODS:A systematic literature review (Medline, EMBASE, BIOSIS; 1996-2007) identified six randomis...

journal_title：Current medical research and opinion

authors： Vissers D,Stam W,Nolte T,Lenre M,Jansen J

更新日期：2010-05-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVE:The management of hyponatremia has evolved in recent years, particularly with the introduction of tolvaptan for hyponatremia secondary to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). This commentary presents a summary of recent international recommendations in the for...

journal_title：Current medical research and opinion

authors： Aylwin S,Burst V,Peri A,Runkle I,Thatcher N

更新日期：2015-01-01 00:00:00

abstract：:A double-blind trial was carried out in 76 patients with active rheumatoid arthritis to compare the analgesic and anti-inflammatory activity of 3 g. alclofenac with 4.8 g. aspirin daily over a 6-week period. All patients selected showed reversible inflammatory swelling of the finger joints. Of the 60 patients successf...

journal_title：Current medical research and opinion

authors： Bedi SS

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:To describe the impact of migraine on psychological well-being of young women and to evaluate their communication with physicians about migraine. RESEARCH DESIGN AND METHODS:This cross-sectional telephone survey was conducted in Israel and eight European countries (Finland, Germany, Greece, Italy, Norway, Sp...

journal_title：Current medical research and opinion

authors： Dueland AN,Leira R,Cabelli ST

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:To compare real-world adherence to and persistence with deferasirox film-coated tablets (DFX-FCT) and deferasirox dispersible tablets (DFX-DT) among patients who switched from DFX-DT to DFX-FCT, overall and by disease type (sickle cell disease [SCD], thalassemia, and myelodysplastic syndrome [MDS]). METHODS:...

journal_title：Current medical research and opinion

authors： Cheng WY,Said Q,Hao Y,Xiao Y,Vekeman F,Bobbili P,Duh MS,Nandal S,Blinder M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Aripiprazole differs from other atypical antipsychotics in its pharmacological and clinical profile. SCOPE:As aripiprazole has been available in the USA for bipolar mania since 2004, clinical experience-sharing from clinical and research use of this agent can assist with initiation and administration in pra...

journal_title：Current medical research and opinion

authors： Fagiolini A

更新日期：2008-09-01 00:00:00

abstract：INTRODUCTION:GOLD guideline recommendations are currently the "gold standard" for the treatment of COPD patients. OBJECTIVES:The objective of this analysis was to evaluate compliance with GOLD guidelines in managing COPD patients' treatment by general practitioners (GPs) and pulmonologists. Since inhaled corticosteroi...

journal_title：Current medical research and opinion

authors： Visentin E,Nieri D,Vagaggini B,Peruzzi E,Paggiaro P

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To compare injection site pain of subcutaneous (sc) epoetin beta and darbepoetin alfa in adult patients with chronic kidney disease. RESEARCH DESIGN AND METHODS:This was a multi-centre, randomised, two-arm, single-blind, cross-over study. Patients were randomised to receive weekly sc darbepoetin alfa 30 mug ...

journal_title：Current medical research and opinion

authors： Roger SD,Suranyi MG,Walker RG,Disney A,Isbel NM,Kairaitis L,Pollock CA,Brown FG,Chow J,Truman MI,Ulyate KA,COMFORT study group.

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVES:To compare 1-year direct healthcare costs and utilization among children and adolescents initiating non-stimulant medications atomoxetine (ATX) or extended-release guanfacine (GXR). METHODS:In this retrospective, observational cohort study, children and adolescents aged 6-17 years with attention deficit/hyp...

journal_title：Current medical research and opinion

authors： Molife C,Haynes VS,Nyhuis A,Faries DE,Gelwicks S,Kelsey DK,Alatorre CI

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Statins are hypothesized to have beneficial effects in asthma management through their pleiotropic anti-inflammatory effects. Several studies have examined this relationship, but have yielded conflicting results. This study investigates the effect of statin use on asthma-related hospitalizations and/or emerge...

journal_title：Current medical research and opinion

authors： Tse SM,Charland SL,Stanek E,Herrera V,Goldfarb S,Litonjua AA,Weiss ST,Wu AC

更新日期：2014-04-01 00:00:00

abstract：:Elevated serum cholesterol level is a key risk factor for cardiovascular morbidity and mortality. Cerivastatin is a highly effective lipid-lowering agent currently licensed at doses of 0.1, 0.2, 0.3 and 0.4 mg. This was a multicentre, randomised, double-blind, parallel-group study comparing the efficacy and safety of ...

journal_title：Current medical research and opinion

authors： Ose L,Luurila O,Eriksson J,Olsson A,Lithell H,Widgren B

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:There are contrasting positions concerning the benefit-risk ratio of acetaminophen use for osteoarthritis (OA)-related pain. To clarify the effectiveness of acetaminophen or acetaminophen-codeine combinations according to their regimen of use, we evaluated whether being a regular user (adherent) of these medi...

journal_title：Current medical research and opinion

authors： Vannacci A,Lombardi N,Simonetti M,Fornasari D,Fanelli A,Cricelli I,Cricelli C,Lora Aprile P,Lapi F

更新日期：2017-06-01 00:00:00

abstract：:A multi-centre, double-blind trial was carried out in general practice in 44 patients with symptoms of neurotic anxiety to compare the effects of treatment with either 400 mg chlormezanone at night or 5 mg diazepam 3-times daily for 4 weeks. The results indicated tht there were similar improvements in anxiety, duratio...

journal_title：Current medical research and opinion

authors： Allin DM

更新日期：1982-01-01 00:00:00

abstract：:Objective: The aim of this study was to investigate the impact of methodological choices in a meta-analysis of real-world evidence (RWE) comparing three non-vitamin-K antagonist oral anticoagulants with vitamin K antagonists (VKAs) for the treatment of patients with non-valvular atrial fibrillation (NVAF). Methods: Th...

journal_title：Current medical research and opinion

authors： Briere JB,Wu O,Bowrin K,Millier A,Toumi M,Taieb V,Levy P,Coleman CI

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Resistance to endocrine treatment generally occurs over time, especially in the metastatic stage. In this paper, we aimed to review the mechanisms of cyclin-dependent kinase (CDK) 4/6 inhibition and clinical usage of new agents in the light of recent literature updates. SCOPE:A literature search was carried...

journal_title：Current medical research and opinion

authors： Bilgin B,Sendur MAN,Şener Dede D,Akıncı MB,Yalçın B

更新日期：2017-09-01 00:00:00

abstract：:Seventy frail elderly patients attending a day hospital were studied to investigate the incidence of postural hypotension in control patients on no diuretic treatment (n = 30), patients on loop diuretics (frusemide) for mild cardiac failure (n = 20) and patients on thiazide diuretics for mild cardiac failure (n = 20)....

journal_title：Current medical research and opinion

authors： Heseltine D,Bramble MG

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Description of risk of cardiovascular (CV) events associated with diabetes is evolving. This US-based real-world study estimated risk of future CV events and heart failure (HF) from type 2 diabetes (T2DM) only, prior CV events only or T2DM plus prior CV events, versus controls, and evaluated healthcare resou...

journal_title：Current medical research and opinion

authors： Nguyen C,Luthra R,Kuti E,Willey VJ

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to ascertain the factors associated with non-achievement of triglyceride (TG) goals in a cohort of hypertriglyceridemic patients attending the lipid clinics of the Spanish Arteriosclerosis Society (LC-SAS). METHODS:Patients with high TG levels (>2.2 mmol/L; 200 mg/dL) were included...

journal_title：Current medical research and opinion

authors： Pintó X,Valdivielso P,Perez de Juan JM,Plana N,Garcia-Arias C,Fuentes FJ,Hernández-Mijares A,Mostaza JM,Spanish Registry of Hypertriglyceridemia (Spanish Society of Arteriosclerosis, SAS).

更新日期：2014-01-01 00:00:00

abstract：:Three methods for the determination of azapropazone were studied for the analysis of blood plasma samples taken after oral administration of azapropazone. A gas chromatographic method was compared with two simple spectrophotometric assay methods and the effect of metabolites of the drug on each method is described. It...

journal_title：Current medical research and opinion

authors： Leach H

更新日期：1976-01-01 00:00:00

abstract：:Four hundred and twenty-seven hypertensive patients in the United Kingdom have so far been admitted to two on-going open multicentre trials, and have been treated with acebutolol for periods ranging from 1 to 6 months. Oral dosages were within the range of 100 mg to 1200 mg/day in divided doses and were increased or d...

journal_title：Current medical research and opinion

authors： Ashton WL

更新日期：1976-01-01 00:00:00

abstract：:A clinical study was carried out to evaluate the usefulness of intravenous lorazepam, given for sedation instead of opiate narcotics or diazepam, in 25 seriously-ill patients being treated in a respiratory and intensive care unit. All but 3 patients were on assisted ventilation. Standard doses of 4 mg lorazepam were g...

journal_title：Current medical research and opinion

authors： Dundee JW,Johnston HM,Gray RC

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:Pharmaceutical preparations of human menopausal gonadotrophin (hMG), urine-derived follicle-stimulating hormone (u-FSH) and highly purified u-FSH (u-FSH-HP) have been available since the early 1960s and the mid 1980s and 1990s, respectively. Another commercial preparation of u-FSH-HP, Folyrmon P, was launched...

journal_title：Current medical research and opinion

authors： Bassett R,Ceccarelli D,Crisci C,di Tria AM,Mancinelli M,Martelli F,Mendola D,Pezzotti A

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Despite a plethora of published data on levocetirizine, no meta-analyses exist on the effect of study design, and covariates like age, gender, and baseline symptom severity on treatment response. The objective of this study was the efficacy of levocetirizine 5  mg tablets and matching placebo at reducing alle...

journal_title：Current medical research and opinion

authors： Boev R,Song D,Bedenbaugh A,Haeusler JM

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Aliskiren is the first in a new class of orally effective direct renin inhibitors approved for the treatment of hypertension. This multiple-dose study investigated the potential for pharmacokinetic interactions between aliskiren and three drugs, each predominantly eliminated by a different clearance/metabolic...

journal_title：Current medical research and opinion

authors： Ayalasomayajula S,Tchaloyan S,Yeh CM,Bizot MN,Dieterich HA,Howard D,Dole WP

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:These studies evaluated the safety and efficacy of enteric-coated budesonide for the induction and maintenance of remission of mild-to-moderate Crohn's disease (CD) in children. METHODS:The consecutive, multicenter, open-label, non-comparative studies enrolled patients aged 6-17 years. In the induction study...

journal_title：Current medical research and opinion

authors： Cohen SA,Aloi M,Arumugam R,Baker R,Bax K,Kierkuś J,Koletzko S,Lionetti P,Persson T,Eklund S

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:To compare glycemic goal achievement (HbA(1c) < 7%) in type 2 diabetes patients receiving initial metformin plus pioglitazone combination therapy and initial metformin monotherapy augmented with pioglitazone in a cohort follow-up study. RESEARCH DESIGN AND METHODS:Adult patients were identified from the Inge...

journal_title：Current medical research and opinion

authors： Pandya BJ,Bron M,McCall T,Yu AP,Chen KS,Mattson ME,Wu EQ

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the effects of losartan +/- hydrochlorothiazide (HCTZ) versus placebo in obese patients with systolic and diastolic hypertension. RESEARCH DESIGN AND METHODS:Randomized patients (n = 261) were non-diabetic with systolic blood pressure (SBP) > or = 140 and < or = 1...

journal_title：Current medical research and opinion

authors： Oparil S,Abate N,Chen E,Creager MA,Galet V,Jia G,Julius S,Lerman A,Lyle PA,Pool J,Tershakovec AM

更新日期：2008-04-01 00:00:00

abstract：UNLABELLED:The occurrence of intestinal bacterial overgrowth in patients with Crohn's Disease (CD) has been described and antimicrobial treatment has been shown to be effective in reversing this condition. However, the mechanisms underlying the efficacy of antimicrobial therapy are still only partially known. The aim o...

journal_title：Current medical research and opinion

authors： Biancone L,Vernia P,Agostini D,Ferrieri A,Pallone F

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:Detection of β-thalassemia trait or carriers (β-TT) depends significantly on an increase in Hemoglobin A2 (HbA2) levels, which is found at low levels (<3%) in normal healthy individuals and elevated levels (≥3.5%) in β-TT individuals. The study was designed to evaluate the reliability of the diagnostic par...

journal_title：Current medical research and opinion

authors： Al-Amodi AM,Ghanem NZ,Aldakeel SA,Ibrahim Al Asoom L,Rafique Ahmed N,Almandil NB,Naserullah ZA,Al-Jarrash S,Shakil Akhtar M,AbdulAzeez S,Al-Ali AK,Borgio JF

更新日期：2018-05-01 00:00:00

abstract：:One hundred adult male volunteers were randomized to receive either Merieux or Wellcome RA27/3 rubella vaccine. Prior to vaccination, 10% of the subjects were seronegative and all of these seroconverted. No significant boosting effect was found in those with a high pre-vaccine titre but some boost was shown in those w...

journal_title：Current medical research and opinion

authors： Harcus AW,Ward AE,Bryett KA

更新日期：1986-01-01 00:00:00