'Dos and don'ts' in the management of hyponatremia.

abstract：:Type 2 diabetes mellitus is a public health problem of epidemic proportions and its prevalence is on the rise. The typical American born today has a one in three chance of developing type 2 diabetes. This diagnosis is associated with an adverse cardiovascular prognosis and is considered the risk equivalent of establis...

journal_title：Current medical research and opinion

authors： Abuissa H,Bel DS,O'keefe JH Jr

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:To compare the efficacy and safety of ciprofloxacin 0.3%/dexamethasone 0.1% (CIP/DEX) otic suspension with that of neomycin 0.35%/polymyxin B 10,000 IU/mL/hydrocortisone 1.0% (N/P/H) otic suspension in patients with acute otitis externa (AOE). STUDY DESIGN:Randomized, observer-masked, parallel-group, multic...

journal_title：Current medical research and opinion

authors： Roland PS,Pien FD,Schultz CC,Henry DC,Conroy PJ,Wall GM,Garadi R,Dupre SJ,Potts SL,Hogg LG,Stroman DW,Ciprodex Otic AOE Study Group.

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of percutaneous polidocanol injection (PPI) in treatment of predominantly cystic thyroid nodules. MATERIALS AND METHODS:This prospective study included 111 patients with 122 benign predominantly cystic thyroid nodules inducing pressure symptoms or cosmetic problems. The no...

journal_title：Current medical research and opinion

authors： Gong X,Zhou Q,Chen S,Wang F,Wu W,Chen X

更新日期：2017-08-01 00:00:00

abstract：:Objective: Hypertension is a serious health problem in Egypt, with prevalence rate of 17% as reported in 2015. Despite receiving treatment, many do not achieve blood pressure (BP) control. The current study aimed to evaluate the efficacy and tolerability of amlodipine/valsartan/hydrochlorothiazide (Aml/Val/HCTZ) singl...

journal_title：Current medical research and opinion

authors： El-Etriby AMK,Rakha S

更新日期：2020-04-01 00:00:00

abstract：:One hundred and eight patients who had been taking phenytoin for a year or more, either alone or in combination with other drugs, were examined for gum hypertrophy by three observers independently. Approximately 90% of the patients showed either mild or no gum hypertrophy and severe swelling occurred in only 1%. The o...

journal_title：Current medical research and opinion

authors： Grant RH,Parsonage MJ,Barot MH

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:Modern immunology has been extremely successful in elucidating many features of the immune system, but not in stemming pandemics of non-infectious, immune-related disease associated with industrialized populations. These pandemics involve a broad range of allergic, autoimmune, and inflammatory diseases, poten...

journal_title：Current medical research and opinion

authors： Parker W,Perkins SE,Harker M,Muehlenbein MP

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Pharmaceutical preparations of human menopausal gonadotrophin (hMG), urine-derived follicle-stimulating hormone (u-FSH) and highly purified u-FSH (u-FSH-HP) have been available since the early 1960s and the mid 1980s and 1990s, respectively. Another commercial preparation of u-FSH-HP, Folyrmon P, was launched...

journal_title：Current medical research and opinion

authors： Bassett R,Ceccarelli D,Crisci C,di Tria AM,Mancinelli M,Martelli F,Mendola D,Pezzotti A

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVES:High-sensitivity C-reactive protein (hs-CRP) has been explored for use in predicting cardiovascular risk. The recent Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) study found that statin therapy reduced cardiovascular events in those with ...

journal_title：Current medical research and opinion

authors： Slejko JF,Page RL 2nd,Sullivan PW

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To examine outcomes associated with colesevelam treatment among patients with hypercholesterolemia in real-world clinical practice. METHODS:This analysis was conducted as a retrospective, observational cohort study in an ambulatory-care medical network in Northern California. Patients with orders for colesev...

journal_title：Current medical research and opinion

authors： Romanelli RJ,Leahy A,Jukes T,Ye X,Qian C,Ishisaka DY

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The glutathione S-transferases (GST) can metabolise endogenous and exogenous toxins and carcinogens by catalysing the conjugation of diverse electrophiles with reduced glutathione (GSH). Variations of GST enzyme activity could influence the susceptibility of developing cancers in certain areas of the gastroi...

journal_title：Current medical research and opinion

authors： Hoensch H,Peters WH,Roelofs HM,Kirch W

更新日期：2006-06-01 00:00:00

abstract：:Sufficient time and effective communication are the main requirements in an ideal asthma consultation. One way of using limited time effectively is for patients to be offered more information prior to the consultation. Physician-patient communication during the consultation may be improved by patients receiving, in ad...

journal_title：Current medical research and opinion

authors： Partridge MR

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To compare acute normovolemic hemodilution versus low central venous pressure strategy versus conventional fluid management in reducing intraoperative estimated blood loss, hematocrit drop and need for blood transfusion in patients undergoing radical retropubic prostatectomy under general anesthesia. RESEARC...

journal_title：Current medical research and opinion

authors： Habib AS,Moul JW,Polascik TJ,Robertson CN,Roche AM,White WD,Hill SE,Nosnick I,Gan TJ,Duke Perioperative Outcome Study Group.

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Untreated and under-treated pain represent one of the most pervasive health problems, which is worsening as the population ages and accrues risk for pain. Multiple treatment options are available, most of which have one mechanism of action, and cannot be prescribed at unlimited doses due to the ceiling of ef...

journal_title：Current medical research and opinion

authors： Varrassi G,Hanna M,Macheras G,Montero A,Montes Perez A,Meissner W,Perrot S,Scarpignato C

更新日期：2017-06-01 00:00:00

abstract：:Angiotensin converting enzyme (ACE) inhibitors have been avoided as an initial therapeutic option in the treatment of hypertension in African-Americans. A major reason for this has been the widespread perception of clinicians that these agents have poor blood pressure (BP) lowering efficacy in this population. Remarka...

journal_title：Current medical research and opinion

authors： Flack JM,Mensah GA,Ferrario CM

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Thiazide diuretics such as hydrochlorothiazide (HCT) are a widely used first-line treatment for hypertension, but most patients will not achieve blood pressure (BP) control with HCT alone and so will require combination therapy. In this study the efficacy, safety and tolerability of a single-pill combination ...

journal_title：Current medical research and opinion

authors： Blumenstein M,Romaszko J,Calderón A,Andersen K,Ibram G,Liu Z,Zhang J

更新日期：2009-04-01 00:00:00

abstract：:Atypical antipsychotics are commonly used off-label to treat behavioural and psychiatric symptoms in dementia (BPSD), particularly in elderly care homes. Much of this use is inappropriate, and trials have shown an increased likelihood of serious cerebrovascular adverse events (CVAEs) such as stroke and transient ische...

journal_title：Current medical research and opinion

authors： Bullock R

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) can have substantial negative impact on children. Most notably, it can impede learning during the school-age years. Other consequences include adverse behavioral and psychosocial effects, poor quality of life, and potential impact on serious comorbidities, such as asthma. CONSENSUS PA...

journal_title：Current medical research and opinion

authors： Blaiss MS,Allergic Rhinitis in Schoolchildren Consensus Group.

更新日期：2004-12-01 00:00:00

abstract：:A national survey of psychotherapeutic drug use was carried out in the U.S.A. in 1979. Data were obtained from a probability sample (n = 3161) of adults in the general population, using a clinically-oriented interview lasting an average of 90 minutes. The data provide estimates of the prevalence of using anxiolytic an...

journal_title：Current medical research and opinion

authors： Mellinger GD,Balter MB,Uhlenhuth EH

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:Most registration studies for new osteoporosis drugs have used a combination of quantitative morphometry (QM) and visual semiquantitative reading (SQ) to define vertebral fractures. However, in the pivotal teriparatide Fracture Prevention Trial (ClinicalTrials.gov Identifier: NCT00670501), vertebral fractures...

journal_title：Current medical research and opinion

authors： Prevrhal S,Krege JH,Chen P,Genant H,Black DM

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Elevated glucose blood levels are the key criteria for diagnosing diabetes mellitus (DM). Hyperglycaemia contributes to the pathophysiology associated with DM, including microvascular and possibly macrovascular disease. In spite of a wide range of pharmacological options available to reduce hyperglycaemia in...

journal_title：Current medical research and opinion

authors： Bays H

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:The objective of this project was to determine pharmacy cost savings and improvement in adherence based on a combinatorial pharmacogenomic test (CPGx ) in patients who had switched or added a new psychiatric medication after having failed monotherapy for their psychiatric disorder. RESEARCH DESIGN AND METHO...

journal_title：Current medical research and opinion

authors： Winner JG,Carhart JM,Altar CA,Goldfarb S,Allen JD,Lavezzari G,Parsons KK,Marshak AG,Garavaglia S,Dechairo BM

更新日期：2015-01-01 00:00:00

abstract：:Optimal management of hypertension has been shown to reduce the risk of stroke. In recent years, newer classes of antihypertensive such as the angiotensin II (Ang II) antagonists have become available. Results from the Losartan Intervention for Endpoint reduction in hypertension (LIFE) study suggest the utility of thi...

journal_title：Current medical research and opinion

authors： Ferrario CM

更新日期：2004-11-01 00:00:00

abstract：INTRODUCTION:Tumor hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) expression are important factors influencing treatment response and selection in patients with metastatic breast cancer (mBC). Using the LifeLink Oncology Analyzer Database, we classified mBC patients by combined HR and HER2 st...

journal_title：Current medical research and opinion

authors： Gao S,Barber B,Schabert V,Ferrufino C

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:To report on the results of a recent large-scale, internet-based survey of the population, prevalence and attributes of pain experience in the United Kingdom (UK), France, Spain, Germany and Italy. METHODS:The results reported here are taken from the internet-based, 2008 National Health and Wellness Survey ...

journal_title：Current medical research and opinion

authors： Langley PC

更新日期：2011-02-01 00:00:00

abstract：:This double-blind, randomised, placebo-controlled study was carried out to assess the efficacy and safety of 0.025% and 0.05% azelastine eye drops twice daily administered for 14 days to patients with seasonal allergic conjunctivitis or rhinoconjunctivitis. A total of 278 patients were recruited and 226 patients were ...

journal_title：Current medical research and opinion

authors： Lenhard G,Mivsek-Music E,Perrin-Fayolle M,Obtulowicz K,Secchi A

更新日期：1997-01-01 00:00:00

abstract：:The results of a series of studies on body fluid, electrolytes and diuretics are discussed. The findings to date indicate that the sex difference between mean potassium plasma levels in men and women is preserved into old age. Contrary to previous suggestions, there would appear to be no transient self-correcting hypo...

journal_title：Current medical research and opinion

authors： McCarthy ST

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:As an ever widening array of anti-hyperglycemic agents are now available, the effect of these drugs on lipids is increasingly complex and controversial. The present meta-analysis was designed to clarify the effect of a dual combination of noninsulin anti-hyperglycemic agents on lipids in type 2 diabetes. MET...

journal_title：Current medical research and opinion

authors： Dai X,Wang H,Jing Z,Fu P

更新日期：2014-09-01 00:00:00

abstract：:In a study of 32 patients, there were 29 cases of intra-uterine fetal death and 3 cases of hydatidiform mole. The intravenous administration of either prostaglandin E1, E2 or F2 successfully induced labor in 29 out of the 32 cases. 2 patients delivered following additional intravenous oxytocin and there was 1 failur...

journal_title：Current medical research and opinion

authors： Roberts G

更新日期：1974-01-01 00:00:00

abstract：OBJECTIVE:To further assess the clinically active dose range of etoricoxib, a COX-2 selective inhibitor, in rheumatoid arthritis (RA). METHODS:RA patients were randomized to etoricoxib 10, 30, 60, or 90 mg or placebo in a double-blind, 12-week study. DMARDs (methotrexate, biologics) or low-dose corticosteroids were al...

journal_title：Current medical research and opinion

authors： Greenwald M,Peloso PM,Mandel D,Soto O,Mehta A,Frontera N,Boice JA,Zhan XJ,Curtis SP

更新日期：2011-10-01 00:00:00

abstract：:Compatibility of two types of needles with a variety of durable and prefilled injection pens for diabetes medication was tested by attaching the needles according to ISO 11608-2 and verifying penetration into the cartridge using air shots and two-dimensional X-rays. NovoFine* and NovoFine Autocover† attached correctly...

journal_title：Current medical research and opinion

authors： Buus P,Lilleøre SK,Larsen K

更新日期：2011-03-01 00:00:00