Interleukin-3 production as a sensitive measure of T-lymphocyte activation in the mouse.

Abstract:

:Interleukin-3 activity is produced by T cells at an early phase after antigenic stimulation, and its quantitation provides a sensitive and non-destructive method for assaying T-cell activation. It can be detected before increased uptake of [3H]thymidine into DNA occurs, and is more sensitive than measuring [3H]thymidine uptake for low levels of T-cell activation. This method has been shown to be useful in measuring activation of T-cell clones and in detecting antigens that have been blotted onto nitrocellulose.

journal_name

Immunology

journal_title

Immunology

authors

Dotsika EN,Sanderson CJ

subject

Has Abstract

pub_date

1987-12-01 00:00:00

pages

665-8

issue

4

eissn

0019-2805

issn

1365-2567

journal_volume

62

pub_type

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