Genetic analysis of antibiotic resistance in Streptococcus pyogenes.

abstract：:The Gifsy-1 phage integrates site specifically into the Salmonella chromosome via an integrase-mediated site-specific recombination mechanism. Initial genetic analysis suggests that Gifsy-1 integrase-mediated excision of the Gifsy-1 phage is influenced by proteins encoded by both the Gifsy-1 and the Gifsy-2 phages. Ou...

journal_title：Journal of bacteriology

authors： Flanigan A,Gardner JF

更新日期：2007-09-01 00:00:00

abstract：:Netropsin, a polypeptide antibiotic which binds specifically to adenylate-thymidylate-rich regions of deoxyribonucleic acid, inhibitis sporulation at about stage II, but does not inhibit growth of Bacillys subtilis. An analysis of the sporulation-associated enzymes aconitase, alkaline phosphatase, and glucose dehydrog...

journal_title：Journal of bacteriology

authors： Keilman GR,Brutis K,Tanimoto B,Doi RH

更新日期：1976-10-01 00:00:00

abstract：:Lornitzo, Frank A. (Veterans Administration Hospital, Madison, Wis.), and Dexter S. Goldman. Reversible effect of bicarbonate on the inhibition of mycobacterial and yeast transglucosylases by mycoribnin. J. Bacteriol. 89:1086-1091. 1965.-The transglucosylase which catalyzes the formation of trehalose-6-phosphate from ...

journal_title：Journal of bacteriology

authors： LORNITZO FA,GOLDMAN DS

更新日期：1965-04-01 00:00:00

abstract：UNLABELLED:The transmembrane Tsr protein of Escherichia coli mediates chemotactic responses to environmental serine gradients. Serine binds to the periplasmic domain of the homodimeric Tsr molecule, promoting a small inward displacement of one transmembrane helix (TM2). TM2 piston displacements, in turn, modulate the s...

journal_title：Journal of bacteriology

authors： Kitanovic S,Ames P,Parkinson JS

更新日期：2015-08-01 00:00:00

abstract：:Spectinomycin dependence in Bacillus subtilis involves two mutations, one conferring drug resistance and the other producing a requirement for spectinomycin for growth. ...

journal_title：Journal of bacteriology

authors： Henkin TM,Campbell KM,Chambliss GH

更新日期：1979-03-01 00:00:00

abstract：:Among 69 ColE3 mutant plasmids selected on the basis of their inability to produce an active colicin, seven (cop-1 to cop-7) were found to bear a mutation affecting the structural gene for colicin. Three of these (cop-1, cop-2 and cop-3) lead to the production of an inactive colicin molecule which has the same molecul...

journal_title：Journal of bacteriology

authors： Mock M,Schwartz M

更新日期：1980-05-01 00:00:00

abstract：:Deoxyribonucleic acid (DNA), pulse labeled after ultraviolet irradiation of excision-defective mutants of Haemophilus influenzae, is of lower single strand molecular weight than that of unirradiated cells but approaches the size of DNA from unirradiated cells upon further incubation in growth medium. This gap-filling ...

journal_title：Journal of bacteriology

authors： Small GD

更新日期：1975-10-01 00:00:00

abstract：:Gartner, T. K. (University of California, Santa Barbara), and E. Orias. Effects of mutations to streptomycin resistance on the rate of translation of mutant genetic information. J. Bacteriol. 91:1021-1028. 1966.-The effects of mutations to streptomycin resistance of independent origin upon the translation of suppressi...

journal_title：Journal of bacteriology

authors： Gartner TK,Orias E

更新日期：1966-03-01 00:00:00

abstract：:OxyR is a DNA binding protein that differentially regulates a cell's response to hydrogen peroxide-mediated oxidative stress. We previously reported that the reduced form of OxyR is sufficient for repression of transcription of agn43 from unmethylated template DNA, which is essential for deoxyadenosine methylase (Dam)...

journal_title：Journal of bacteriology

authors： Wallecha A,Correnti J,Munster V,van der Woude M

更新日期：2003-04-01 00:00:00

abstract：:Lundgren, D. G. (Syracuse University, Syracuse, N.Y.) and J. J. Cooney. Chemical analyses of asporogenic mutants of Bacillus cereus. J. Bacteriol. 83:1287-1293. 1962.-Bacillus cereus ATCC 4342 and three temperature-sensitive asporogenic mutants were compared regarding some basic cellular components and response to met...

journal_title：Journal of bacteriology

authors： LUNDGREN DG,COONEY JJ

更新日期：1962-06-01 00:00:00

abstract：:When an asporogenic diploid yeast, Candida tropicalis, is cultivated on n-alkane, the expression of the genes encoding enzymes of the peroxisomal beta-oxidation pathway is highly induced. An upstream activation sequence (UAS) which can induce transcription in response to n-alkane (UAS(ALK)) was identified on the promo...

journal_title：Journal of bacteriology

authors： Kanai T,Hara A,Kanayama N,Ueda M,Tanaka A

更新日期：2000-05-01 00:00:00

abstract：:Mutans of Pseudomonas testosteroni were isolated for their inability to grow on m-hydroxybenzoate as sole carbon source. These mutants hydroxylated m-hydroxybenzoate for form 2,3-dihydroxybenzoate in high yeilds. The bioconversion described in this report represents the first reported example of 3-hydroxybenzoate 2-hy...

journal_title：Journal of bacteriology

authors： Daumy GO,McColl AS,Andrews GC

更新日期：1980-01-01 00:00:00

abstract：:The Lyme disease spirochete Borrelia burgdorferi is unique among bacteria in its large number of lipoproteins that are encoded by a small, exceptionally fragmented, and predominantly linear genome. Peripherally anchored in either the inner or outer membrane and facing either the periplasm or the external environment, ...

journal_title：Journal of bacteriology

authors： Dowdell AS,Murphy MD,Azodi C,Swanson SK,Florens L,Chen S,Zückert WR

更新日期：2017-02-28 00:00:00

abstract：:In Escherichia coli, the phn operon encodes proteins responsible for the uptake and breakdown of phosphonates. The C-P (carbon-phosphorus) lyase enzyme encoded by this operon which catalyzes the cleavage of C-P bonds in phosphonates has been recalcitrant to biochemical characterization. To advance the understanding of...

journal_title：Journal of bacteriology

authors： Parker GF,Higgins TP,Hawkes T,Robson RL

更新日期：1999-01-01 00:00:00

abstract：:In Escherichia coli, nine essential cell division proteins are known to localize to the division septum. FtsL is a 13-kDa bitopic membrane protein with a short cytoplasmic N-terminal domain, a membrane-spanning segment, and a periplasmic domain that has a repeated heptad motif characteristic of leucine zippers. Here, ...

journal_title：Journal of bacteriology

authors： Ghigo JM,Beckwith J

更新日期：2000-01-01 00:00:00

abstract：:Beta toxin is a neutral sphingomyelinase secreted by certain strains of Staphylococcus aureus. This virulence factor lyses erythrocytes in order to evade the host immune system as well as scavenge nutrients. The structure of beta toxin was determined at 2.4-A resolution using crystals that were merohedrally twinned. T...

journal_title：Journal of bacteriology

authors： Huseby M,Shi K,Brown CK,Digre J,Mengistu F,Seo KS,Bohach GA,Schlievert PM,Ohlendorf DH,Earhart CA

更新日期：2007-12-01 00:00:00

abstract：:Deoxyribonucleic acid (DNA) reassociation analyses were employed to determine the molecular relationships between recombinable nocardiae. Analysis of the compatibility system of Nocardia erythropolis Mat-Ce and Mat-cE mating strains demonstrated the existence of extensive homology under both exacting and nonexacting c...

journal_title：Journal of bacteriology

authors： Clark JE,Brownell GH

更新日期：1972-02-01 00:00:00

abstract：:We previously reported that the methicillin resistance gene mecA is carried by a novel type of mobile genetic element, SCCmec (staphylococcal cassette chromosome mec), in the chromosome of methicillin-resistant Staphylococcus aureus (MRSA). These elements are precisely excised from the chromosome and integrated into a...

journal_title：Journal of bacteriology

authors： Katayama Y,Takeuchi F,Ito T,Ma XX,Ui-Mizutani Y,Kobayashi I,Hiramatsu K

更新日期：2003-05-01 00:00:00

abstract：:The ribosome content was markedly reduced when illumination (at 28 C) was repeatedly interrupted; an opposite trend was observed with continuous light as the temperature was decreased. ...

journal_title：Journal of bacteriology

authors： Din GA,Gest H

更新日期：1969-03-01 00:00:00

abstract：:Tn5 insertion mutations in the recN gene, and in what appears to be a new RecF pathway gene designated recO and mapping at approximately 55.4 min on the standard genetic map, were isolated by screening Tn5 insertion mutations that cotransduced with tyrA. The recO1504::Tn5 mutation decreased the frequency of recombinat...

journal_title：Journal of bacteriology

authors： Kolodner R,Fishel RA,Howard M

更新日期：1985-09-01 00:00:00

abstract：:Glucose-adapted cells of a sporogenic mutant. MSp(+), and an asporogenic mutant, RSpoIIIa, of Clostridium botulinum type E rapidly fermented glucose, fructose, maltose, and sucrose, resulting in cytoplasmic granulation, heavy growth, a pH of <6.0, and sporulation of the MSp(+) mutant ranging from 60 to 80%. In Tryptic...

journal_title：Journal of bacteriology

authors： Emeruwa AC,Hawirko RZ,Halvorson H,Suzuki I

更新日期：1974-10-01 00:00:00

abstract：:Dworkin, Martin (Indiana University Medical Center, Indianapolis, Ind.). Nutritional requirements for vegetative growth of Myxococcus xanthus. J. Bacteriol. 84:250-257. 1962.-This investigation was part of a program to clarify the environmental regulation of fruiting-body formation in a fruiting myxobacterium. By use ...

journal_title：Journal of bacteriology

authors： DWORKIN M

更新日期：1962-08-01 00:00:00

abstract：:The PDC1 gene coding for a pyruvate decarboxylase (PDC; EC 4.1.1.1) was deleted from the Saccharomyces cerevisiae genome. The resulting pdc1(0) mutants were able to grow on glucose and still contained 60 to 70% of the wild-type PDC activity. Two DNA fragments with sequences homologous to that of the PDC1 gene were clo...

journal_title：Journal of bacteriology

authors： Seeboth PG,Bohnsack K,Hollenberg CP

更新日期：1990-02-01 00:00:00

abstract：:The mutations of eight chemotaxis-deficient strains of Salmonella typhimurium, including five new mutants in strain LT2, were mapped by P22 transduction in relation to various fla mot deletions in S. abortus-equi. Seven recessive che mutations mapped between motB and flaC: three, all nontumbling, the che region I, adj...

journal_title：Journal of bacteriology

authors： Collins AL,Stocker BA

更新日期：1976-12-01 00:00:00

abstract：:In bacteria, normal mutation frequencies are mostly around 10(-10) per base pair. However, there exists natural isolates, called "mutators," that exhibit permanent mutation occurrences up to 1,000-fold greater than usual. As mutations play essential roles, particularly in the evolution of antibiotic resistance, bacter...

journal_title：Journal of bacteriology

authors： Le Bars H,Bousarghin L,Bonnaure-Mallet M,Jolivet-Gougeon A,Barloy-Hubler F

更新日期：2012-07-01 00:00:00

abstract：:Most iron in mammals is found within the heme prosthetic group. Consequently, many bacterial pathogens possess heme acquisition systems to utilize iron from the host. Here, we demonstrate that Mycobacterium tuberculosis can utilize heme as an iron source, suggesting that M. tuberculosis possesses a yet-unknown heme ac...

journal_title：Journal of bacteriology

authors： Jones CM,Niederweis M

更新日期：2011-04-01 00:00:00

abstract：:The metD D-methionine transporter locus of Escherichia coli was identified as the abc-yaeE-yaeC cluster (now renamed metNIQ genes). The abc open reading frame is preceded by tandem MET boxes bracketed by the -10 and -35 boxes of a promoter. The expression driven by this promoter is controlled by the MetJ repressor and...

journal_title：Journal of bacteriology

authors： Gál J,Szvetnik A,Schnell R,Kálmán M

更新日期：2002-09-01 00:00:00

abstract：:We have sequenced the rightmost 1,700 base pairs of bacteriophage PRD1. This region encompasses the right early region and completes the sequence of all PRD1 early functions. We have also mapped the 5' initiation site of right early transcripts in vivo and in vitro. This has allowed us to assign gene XII to an open re...

journal_title：Journal of bacteriology

authors： Gerendasy D,Ito J

更新日期：1990-04-01 00:00:00

abstract：:A previous bioinformatics-based search for small RNAs in Escherichia coli identified a novel RNA named IS183. The gene encoding this small RNA is located between and on the opposite strand of genes encoding two transcriptional regulators of the acid response, gadX (yhiX) and gadW (yhiW). Given that IS183 is encoded in...

journal_title：Journal of bacteriology

authors： Opdyke JA,Kang JG,Storz G

更新日期：2004-10-01 00:00:00

abstract：:CTXphi is a filamentous, lysogenic bacteriophage whose genome encodes cholera toxin, the primary virulence factor produced by Vibrio cholerae. CTX prophages in O1 El Tor and O139 strains of V. cholerae are found within arrays of genetically related elements integrated at a single locus within the V. cholerae large chr...

journal_title：Journal of bacteriology

authors： Davis BM,Moyer KE,Boyd EF,Waldor MK

更新日期：2000-12-01 00:00:00