The effect of erythrocyte associated light scattering on membrane fluorescence polarization.

abstract：:When cells of the thymus or mouse leukemias P288 and L1210 are exposed in vitro to the potent synthetic glucocorticoid, 3H-Triamcinolone acetonide, the steroid enters the cells passively and binds to macromolecules in the cytoplasm. At 37 degrees C this hormone-receptor complex enters the nucleus and associates with t...

journal_title：Molecular and cellular biochemistry

authors： Turnell RW,Burton AF

更新日期：1975-12-31 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) are known as crucial regulators in the development of OC. In the current study, we aim to explore the function and molecular mechanism of lncRNA DLEU1 in OC. Quantitative real-time polymerase chain reaction (qRT-PCR) was applied to determine the expression of DLEU1, miR-429, and TFAP2A i...

journal_title：Molecular and cellular biochemistry

authors： Xu H,Wang L,Jiang X

更新日期：2020-11-10 00:00:00

abstract：:Vasculogenesis was long considered to be a mechanism of blood vessel formation limited to the embryo, and not used in adult vascular repair. Similarly, myocardial proliferation was generally thought to cease in the adult. Yet there is an extensive older literature suggesting that blood might be a source of adult angio...

journal_title：Molecular and cellular biochemistry

authors： Schatteman GC

更新日期：2004-09-01 00:00:00

abstract：:Previous results from our laboratory have shown that a novel carotenoid derivative (disodium disuccinate astaxanthin; Cardax) produced dose-related reductions in myocardial infarct size (IS) in Sprague-Dawley rats when it was administered at any of three doses (25, 50 and 75 mg/kg, iv) on four consecutive days, follow...

journal_title：Molecular and cellular biochemistry

authors： Gross GJ,Lockwood SF

更新日期：2005-04-01 00:00:00

abstract：:Hyperlipidemia is a well-known risk factor for atherosclerosis and statins are widely used to treat patients with elevated levels of lipids in their plasma. Notwithstanding the proven benefits of statin drugs on both primary and secondary prevention of heart disease, the high cost of statin treatment, in addition to p...

journal_title：Molecular and cellular biochemistry

authors： Man RY,Lynn EG,Cheung F,Tsang PS,O K

更新日期：2002-04-01 00:00:00

abstract：:Ganglioside GM3 plays a well-documented and important role in the regulation of tumor cell proliferation, invasion, and metastasis by modulating tyrosine kinase growth factor receptors. However, the effect of GM3 on the hepatocyte growth factor receptor (HGFR, cMet) has not been fully delineated. In the current study,...

journal_title：Molecular and cellular biochemistry

authors： Li Y,Huang X,Zhong W,Zhang J,Ma K

更新日期：2013-10-01 00:00:00

abstract：:Both idiopathic restrictive cardiomyopathy (IRCM) and hypertrophic cardiomyopathy (HCM) are part of the same disease spectrum and are due to sarcomeric gene mutations. A patient with restrictive physiology without left ventricular hypertrophy (LVH) would be diagnosed as IRCM, while one with LVH would be diagnosed as H...

journal_title：Molecular and cellular biochemistry

authors： Rai TS,Ahmad S,Ahluwalia TS,Ahuja M,Bahl A,Saikia UN,Singh B,Talwar KK,Khullar M

更新日期：2009-11-01 00:00:00

abstract：:Population data have consistently demonstrated a correlation between circulating branched-chain amino acids (BCAA) and insulin resistance. Most recently valine catabolite, 3-hydroxyisobutyrate, has emerged as a potential cause of BCAA-mediated insulin resistance; however, it is unclear if valine independently promotes...

journal_title：Molecular and cellular biochemistry

authors： Rivera ME,Lyon ES,Johnson MA,Sunderland KL,Vaughan RA

更新日期：2020-05-01 00:00:00

abstract：:The expression of 76 sequences, previously isolated as differentially expressed in visceral white adipose tissue (WAT) of female rats, fed with a high-fat diet for 11 days (Lopez et al., Biochem Biophys Res Comm 318: 234-239, 2004), was analyzed in epidydimal WAT of male rats after a feeding period of 65 days with the...

journal_title：Molecular and cellular biochemistry

authors： Lopez IP,Milagro FI,Marti A,Moreno-Aliaga MJ,Martinez JA,De Miguel C

更新日期：2005-07-01 00:00:00

abstract：:Calycopterin is a flavonoid compound isolated from Dracocephalum kotschyi that has multiple medical uses, as an antispasmodic, analgesic, anti-hyperlipidemic, and immunomodulatory agents. However, its biological activity and the mechanism of action are poorly investigated. Herein, we investigated the apoptotic effect ...

journal_title：Molecular and cellular biochemistry

authors： Esmaeili MA,Farimani MM,Kiaei M

更新日期：2014-12-01 00:00:00

abstract：:Parkinson disease (PD) is a neurodegenerative disease characterized by progressive dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) area. The present study was undertaken to evaluate the neuroprotective effect of β-caryophyllene (BCP) against rotenone-induced oxidative stress and neuroinflamm...

journal_title：Molecular and cellular biochemistry

authors： Ojha S,Javed H,Azimullah S,Haque ME

更新日期：2016-07-01 00:00:00

abstract：:For the past 40 years, anabolic-androgenic steroids have been used by a wide variety of athletes with the hope of improving their training, endurance, and performance. The aim of this study was to examine the chronic effects of nandrolone decanoate (20 mg/kg, s.c, Deca-Durabolin DECA(®)) on oxidative stress biomarkers...

journal_title：Molecular and cellular biochemistry

authors： Nikolic T,Zivkovic V,Jevdjevic M,Djuric M,Srejovic I,Djuric D,Jeremic N,Djuric D,Bolevich S,Jakovljevic V

更新日期：2016-01-01 00:00:00

abstract：:Interleukin 8 (IL-8) is a chemoattractant associated with ovulation in the mammalian ovary. This chemokine is also involved in the recruitment and activation of neutrophils. Using bovine tissue, we examined the possible role of IL-8 in steroid production by theca cells of the large ovarian follicles. IL-8 promoted pro...

journal_title：Molecular and cellular biochemistry

authors： Shimizu T,Imamura E,Magata F,Murayama C,Miyamoto A

更新日期：2013-02-01 00:00:00

abstract：:Endocrine disruptors have become a global social and public health problem since the late 1980s. Bisphenol A (BPA) has a steroid-like skeleton similar to estrogen and progesterone, and is an endocrine disruptor that disturbs the physiological hormone balance. The potential involvement of BPA in malignancy of endometri...

journal_title：Molecular and cellular biochemistry

authors： Yaguchi T

更新日期：2019-02-01 00:00:00

abstract：:Glutathione plays a central role in the maintenance of tissue antioxidant defenses and in the regulation of redox sensitive signal transduction. In muscle cells, the level and redox status of GSH regulates activity of the redox sensitive transcription factor NF-kappaB. Physical exercise may cause oxidation of GSH in t...

journal_title：Molecular and cellular biochemistry

authors： Sen CK

更新日期：1999-06-01 00:00:00

abstract：:Sustained cardiac hypertrophy (CH) is related to a variety of physiological as well as pathological stimuli and eventually increases the risk of heart failure. HOTAIR has been identified as a competing endogenous RNA in multiple human biological processes. Whether lncRNA-HOTAIR is involved in the progress of CH and ho...

journal_title：Molecular and cellular biochemistry

authors： Lai Y,He S,Ma L,Lin H,Ren B,Ma J,Zhu X,Zhuang S

更新日期：2017-08-01 00:00:00

abstract：:Microtubule-associated proteins (MAPs) were separated from tubulin with several different methods. The ability of the isolated MAPs to reinduce assembly of phosphocellulose purified tubulin differed markedly between the different methods. MAPs isolated by addition of 0.35 M NaCl to taxol-stabilized microtubules stimul...

journal_title：Molecular and cellular biochemistry

authors： Fridén B,Wallin M

更新日期：1991-07-10 00:00:00

abstract：:Young female Zucker fa/fa rats of 370-430 g were implanted with osmotic minipumps releasing 3.5 micromol/day-kg of estrone oleate in liposomes (Merlin-2) into the bloodstream for up to 14 days. Merlin-2 induced a sustained loss of appetite, and a decrease in body weight of 3.5%, which contrasts with the 8.2% increase ...

journal_title：Molecular and cellular biochemistry

authors： Adán C,Grasa MM,Cabot C,Esteve M,Vilà R,Masanés R,Estruch J,Fernández-López JA,Remesar X,Alemany M

更新日期：1999-07-01 00:00:00

abstract：:Human papillomavirus (HPV) is considered to be a major etiological factor but is not sufficient for the development of cervical cancer. Other host factors including altered tumor suppressor gene activities might contribute to the carcinogenic process. Fragile Histidine Triad (FHIT) has been shown to play a pivotal rol...

journal_title：Molecular and cellular biochemistry

authors： Neyaz MK,Hussain S,Hassan MI,Das BC,Husain SA,Bharadwaj M

更新日期：2010-02-01 00:00:00

abstract：:Recently, it has been appreciated that cultured mast cells are significant sources of cytokines. However, the role of interkeukin-1 (IL-1) on mast cells and/or basophil degranulation is still unclear. In this report we provide evidence that rat basophilic leukemia cells (RBLC) cultured with a natural inhibitor of IL-1...

journal_title：Molecular and cellular biochemistry

authors： Conti P,Bouchet W,Feliciani C,Mammarella S,Kudchadker L,Barbacane RC,Reale M,Haggag I,Bruneau G,Thibault J,Theoharides TC

更新日期：1996-02-09 00:00:00

abstract：:Cytokines from the interleukin-6 (IL-6) family have been reported to play an important synergistic role with angiotensin II in the development of pathological cardiac hypertrophy. Whether their expression pattern changes in vivo, in an angiotensin I-dependent hypertrophied myocardium has not been reported. In this stu...

journal_title：Molecular and cellular biochemistry

authors： Kurdi M,Randon J,Cerutti C,Bricca G

更新日期：2005-01-01 00:00:00

abstract：:7,12-Dimethylbenz(a)anthracene (DMBA)-induced hamster buccal pouch carcinogenesis is widely preferred to assess the tumor-inhibiting efficacy of the medicinal plants or their constituents. The present study explores the tumor-inhibiting potential of esculetin by utilizing the status of lipid peroxidation by products (...

journal_title：Molecular and cellular biochemistry

authors： Selvasundaram R,Manoharan S,Buddhan R,Neelakandan M,Murali Naidu R

更新日期：2018-11-01 00:00:00

abstract：:Casein kinase II is a protein serine/threonine kinase that is ubiquitously distributed in eukaryotes. Molecular cloning studies and protein sequence analysis of purified proteins have demonstrated the existence of two related, but distinct, isoenzymic forms of its catalytic subunit in mammals and birds. At present, th...

journal_title：Molecular and cellular biochemistry

authors： Litchfield DW,Lüscher B

更新日期：1993-11-01 00:00:00

abstract：:Human monoblastoid cells (U937) grown in the presence of therapeutically relevant dideoxycytidine concentrations (0.1 microM) become resistant to the drug thanks to an altered deoxycytidine kinase. In this paper we show that deoxycytidine kinase mRNA is significantly reduced in drug-resistant U937 cells (U937-R) altho...

journal_title：Molecular and cellular biochemistry

authors： Innoceta A,Galluzzi L,Ruzzo A,Andreoni F,Chiarantini L,Magnani M

更新日期：2002-02-01 00:00:00

abstract：:The localization of the membrane-bound cyclic 3',5'-AMP phosphodiesterase in cardiac tissues of both, rat and dog was studied by cytochemical method. 40 microm thick slices from glutaraldehyde fixed heart tissue were incubated in the medium with cAMP as a substrate and Pb ions as a capture metal of the reaction produc...

journal_title：Molecular and cellular biochemistry

authors： Okruhlicová L,Tribulová N,Styk J,Eckly A,Lugnier C,Slezk J

更新日期：1997-08-01 00:00:00

abstract：:Hydrogen sulfide (H2S) has been investigated widely in recent years. H2S plays a variety of roles in different biological systems, including cardiovascular system. It is the final product of amino acids metabolism, which contains sulfur-cysteine and homocysteine (Hcy). In human plasma, there are several various forms ...

journal_title：Molecular and cellular biochemistry

authors： Olas B,Kontek B

更新日期：2015-06-01 00:00:00

abstract：:Nitric oxide (NO) is a messenger molecule which regulates many physiological functions like immunity, vascular tone and serves as a neurotransmitter. Although it is known to participate in healing process, its role in collagen synthesis is not clear. Therefore, the present investigation was done to study the role of N...

journal_title：Molecular and cellular biochemistry

authors： Shukla A,Rasik AM,Shankar R

更新日期：1999-10-01 00:00:00

abstract：:Regulation of L-type Ca2+ channels is complex, because many factors, such as phosphorylation, divalent cations, and proteins, specified or unspecified, have been shown to affect the channel activities. An additional complication is that these factors interact with one another to achieve final outcomes. Recent molecula...

journal_title：Molecular and cellular biochemistry

authors： Yamaoka K,Kameyama M

更新日期：2003-11-01 00:00:00

abstract：:The energy metabolism of rat thymus cells has been investigated using preparations of isolated cells obtained by mechanical treatment of whole organs. The addition of glycolytic substrates such as glucose, pyruvate and lactate stimulates the endogenous respiration of these cells by 50%. On the other hand, succinate, g...

journal_title：Molecular and cellular biochemistry

authors： Cittadini A,Bossi D,Longhi G,Terranova T

更新日期：1975-07-31 00:00:00

abstract：:By qualitative and quantitative PCR, we evaluated the expression of three messengers coding for SAT-1, SAT-2 and GalNAcT-1 in human samples of intestinal cancer and some cell lines (breast cancer and melanomas). Qualitative PCR demonstrated, in human tissues but not in the cell lines examined, the presence of an mRNA ...

journal_title：Molecular and cellular biochemistry

authors： Gornati R,Chini V,Rimoldi S,Meregalli M,Schiaffino E,Bernardini G

更新日期：2007-04-01 00:00:00