High-fat feeding period affects gene expression in rat white adipose tissue.

abstract：:The apparent membrane fluorescence anisotropy of 1,6-diphenyl-1,3,5-hexatriene has been reported to be lower in intact erythrocytes than in isolated erythrocyte membranes. Although this difference was once suggested to be caused by the fluidizing effect associated with the loss of erythrocyte proteins during membrane ...

journal_title：Molecular and cellular biochemistry

authors： Dickens BF,Snow TR,Green V,Weglicki WB

更新日期：1988-01-01 00:00:00

abstract：:The aim of the present study was to investigate whether lipid metabolism in the nuclei is affected by changes in the metabolism of free fatty acids in the liver. The experiments were carried out on 3 groups of rats: 1 - control-male, 2 - female, and 3 - male, treated with bezafibrate (a peroxisome proliferator). The r...

journal_title：Molecular and cellular biochemistry

authors： Górski J,Zendzian-Piotrowska M,Wolfrum C,Nawrocki A,Spener F

更新日期：2000-11-01 00:00:00

abstract：:Left ventricular hypertrophy (LVH) increases the risk of cardiovascular morbid events in hypertension. TGF-beta1 is involved in pathologic states such as cardiac hypertrophy and cardiac fibrosis; we thus postulate that the TGF-beta1 polymorphism is related to LVH in hypertensives. Six hundred and eighty essential hype...

journal_title：Molecular and cellular biochemistry

authors： Xu HY,Hou XW,Wang LF,Wang NF,Xu J

更新日期：2010-02-01 00:00:00

abstract：:Albumin complementary DNA (cDNA) was transcribed from purified albumin mRNA from the liver of Xenopus laevis. The resultant cDNA was an almost full length copy as defined by denaturing gel electrophoresis; was hybridized specifically to albumin mRNA with pseudo-first-order reaction kinetics and the mRNA . cDNA hybrid ...

journal_title：Molecular and cellular biochemistry

authors： Dimitriadis GJ,Zongza-Dimitriadis V

更新日期：1983-01-01 00:00:00

abstract：:The AP-1 consensus sequences (TGAGTCA) are the major 12-O-tetradecanoylphorbol113-acetate (TPA) responsive elements shared by several TPA inducible genes, such as c-sis, c-fos, c-myc, collagenase, stromelysin, hMTIIA and SV40. However, the role of AP-1 binding sites, which are present in the introns 3, 5, and 11 of OD...

journal_title：Molecular and cellular biochemistry

authors： Tseng CP,Verma AK

更新日期：1995-05-10 00:00:00

abstract：:Fish and fish oils contain the omega-3 fatty acids known as eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA). Epidemiological studies have shown an inverse relation between the dietary consumption of fish containing EPA/DHA and mortality from coronary heart disease. These relationships have been substantiat...

journal_title：Molecular and cellular biochemistry

authors： Holub DJ,Holub BJ

更新日期：2004-08-01 00:00:00

abstract：:There is a wealth of information regarding the import and export of nuclear proteins in general. Nevertheless, the available data that deals with the nucleocytoplasmic movement of steroid hormone receptors remains highly limited. Some research findings reported during the past five years have succeeded in identifying ...

journal_title：Molecular and cellular biochemistry

authors： Sebastian T,Sreeja S,Thampan RV

更新日期：2004-05-01 00:00:00

abstract：:The actions of cyclic AMP are subject to several levels of post-receptor modulation in cardiac tissue. Isoproterenol and prostaglandin E1 both stimulate cAMP accumulation, but only isoproterenol causes activation of particulate cAMP-dependent protein kinase, leading to activation of phosphorylase kinase and glycogen p...

journal_title：Molecular and cellular biochemistry

authors： Bode DC,Brunton LL

更新日期：1988-07-01 00:00:00

abstract：:In an attempt to understand the functional role of individual transcription factors, we have carried out S1 nuclease analyses of in vitro synthesized RNA using partially purified HeLa cell factors and truncated 5S and tDNA. The results indicate that faithful initiation of 5S gene transcription depends on the presence ...

journal_title：Molecular and cellular biochemistry

authors： Shastry BS

更新日期：1993-04-21 00:00:00

abstract：:We investigated whether chronic in vivo treatment with the peroxisome proliferator-activated receptor alpha agonist Wy-14,643 attenuates cardiac contractile function by impairing mitochondrial respiration. Wy-14,643 (25 mg kg(-1) day(-1)) was administered to Wistar rats by oral gavage for 14 consecutive days, after wh...

journal_title：Molecular and cellular biochemistry

authors： Zungu M,Young ME,Stanley WC,Essop MF

更新日期：2009-10-01 00:00:00

abstract：:Rat pheochromocytoma PC12 cells have been treated with nerve growth factor (NGF) at final concentrations of 2, 4, 8, and 16 ng/ml, and then were exposed to 60-Hz, sinusoidal magnetic fields (MF) of 12.5, 25, 50, and 100 microT (rms) for 30 min. Transcript levels for both c-fos and glyceraldehyde-3 -phosphate dehydroge...

journal_title：Molecular and cellular biochemistry

authors： Campbell-Beachler M,Ishida-Jones T,Haggren W,Phillips JL

更新日期：1998-12-01 00:00:00

abstract：:Enzymes have proven to be sensitive and versatile labels for immunochemical assays. The sensitivity of an enzyme label stems from its extraordinary catalytic power which in turn provides a great amplification of signals. Its versatility, however, stems from the fact that enzyme activity can be modulated by a number of...

journal_title：Molecular and cellular biochemistry

authors： Ngo TT,Lenhoff HM

更新日期：1982-04-16 00:00:00

abstract：:Metabolic syndrome (MetS) is associated with alterations in coronary vascular smooth muscle and endothelial function. The current study examined the contractile response of the isolated coronary arterioles to serotonin in pigs with and without MetS and investigated the signaling pathways responsible for serotonin-indu...

journal_title：Molecular and cellular biochemistry

authors： Lawandy I,Liu Y,Shi G,Zhang Z,Scrimgeour LA,Pavlov V,Jaworski R,Sellke FW,Feng J

更新日期：2019-11-01 00:00:00

abstract：:Dysregulated expression of lysosomal cysteine cathepsins is associated with adverse cardiac remodeling, a characteristic of several cardiovascular diseases. However, the information regarding the role of cysteine cathepsin L (CTSL) and cathepsin B (CTSB) in dilated cardiomyopathy (DCM) is limited. The present study wa...

journal_title：Molecular and cellular biochemistry

authors： Mehra S,Kumar M,Manchanda M,Singh R,Thakur B,Rani N,Arava S,Narang R,Arya DS,Chauhan SS

更新日期：2017-04-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC), which accounts for 10-20% of all breast cancers, has the worst prognosis. Although chemotherapy treatment is a standard for TNBC, it lacks a specific target. Therefore, new therapeutic strategies are required to be investigated. In this study, a combined doxorubicin (DOX) and smal...

journal_title：Molecular and cellular biochemistry

authors： Ciocan-Cȃrtiţă CA,Jurj A,Raduly L,Cojocneanu R,Moldovan A,Pileczki V,Pop LA,Budişan L,Braicu C,Korban SS,Berindan-Neagoe I

更新日期：2020-12-01 00:00:00

abstract：:Acrolein is a highly reactive alpha, beta-unsaturated aldehyde, and a product of lipid peroxidation reactions. Acrolein is also an environmental pollutant and a key component of cigarette smoke, and has been implicated in multiple respiratory diseases. Lung tissue is a primary target for acrolein toxicity in smokers a...

journal_title：Molecular and cellular biochemistry

authors： Sarkar P,Hayes BE

更新日期：2007-07-01 00:00:00

abstract：:Cervical cancer is the most common cancer in Indian females and is associated with infection with high risk Human papillomaviruses (HPVs). Curcumin (Diferuloyl methane), a chemopreventive agent, is a natural compound extracted from Curcuma longa that allows suppression of carcinogenesis. The objective of this study wa...

journal_title：Molecular and cellular biochemistry

authors： Singh M,Singh N

更新日期：2009-05-01 00:00:00

abstract：:The ex vivo and in vitro effects of quercetin on NTPDase, adenosine deaminase (ADA), and acetycholinesterase (AChE) activities in lymphocytes, as well as the effects of quercetin on butyrylcholinesterase (BChE) activity in serum and myeloperoxidase (MPO) activity in plasma were determined in rats. For the ex vivo expe...

journal_title：Molecular and cellular biochemistry

authors： Abdalla FH,Cardoso AM,Schmatz R,Gonçalves JF,Baldissarelli J,Martins CC,Zanini D,de Oliveira LS,da Costa P,Pimentel VC,Pereira LB,Lhamas CL,Schetinger MR,Morsch VM,Mazzanti CM

更新日期：2014-11-01 00:00:00

abstract：:Liver-X-Receptor alpha (LXR-alpha) that belongs to nuclear receptor/transcriptional factor family has been recognized to play crucial role in the regulation of lipid metabolism and inflammation. Consequently, the present study was addressed to explore the functional genomics of LXR-alpha within human blood immunomodul...

journal_title：Molecular and cellular biochemistry

authors： Kaul D,Gautam A,Sikand K

更新日期：2006-11-01 00:00:00

abstract：:Protein kinase CK2 is a highly conserved and ubiquitous serine-threonine kinase. It is a tetrameric enzyme that is made up of two regulatory CK2beta subunits and two catalytic subunits, either CK2alpha/CK2alpha, CK2alpha/CK2alpha', or CK2alpha'/CK2alpha'. Although the two catalytic subunits diverge in their C termini,...

journal_title：Molecular and cellular biochemistry

authors： Seldin DC,Lou DY,Toselli P,Landesman-Bollag E,Dominguez I

更新日期：2008-09-01 00:00:00

abstract：:This paper reviews characteristics of microsomal membrane structure; long chain fatty acids, acyl CoA derivatives, retinoids and the microsomal formation of acyl CoA derivatives and retinyl esters. It is analyzed how the movement of these molecules at the intracellular level is affected by their respective binding pro...

journal_title：Molecular and cellular biochemistry

authors： Catalá A

更新日期：1993-03-24 00:00:00

abstract：:The purification and functional characterization of protein kinase A catalytic subunit (PKAcat) from bovine lens cytosol has been described. Purification to homogeneity has been achieved by using 100 kDa cut-off membrane filtration followed by Sephacryl S-300 chromatography and finally fractionating on High Q anion ex...

journal_title：Molecular and cellular biochemistry

authors： Samanta B,Nagdas SK,Das K,Sen PC

更新日期：2007-10-01 00:00:00

abstract：:A monocyte chemotactic protein (MCP-1) is thought to play a major role in recruiting monocytes to the vascular endothelium where the adherence of monocytes is one of the earliest events in atherogenesis. We cloned MCP-1 cDNA from a lambda gt 11 cDNA library constructed from human aortic endothelial mRNA to test whethe...

journal_title：Molecular and cellular biochemistry

authors： Li YS,Shyy YJ,Wright JG,Valente AJ,Cornhill JF,Kolattukudy PE

更新日期：1993-09-08 00:00:00

abstract：:We have observed that phospholipids and protein of the catecholamine (CA) storage granules, i.e. the chromaffin granules, interact in an in vitro system to form liposomal particles, which in many respects resemble the intact matrix of the bovine chromaffin granule. A model has been suggested which consists of an aqueo...

journal_title：Molecular and cellular biochemistry

authors： Helle KB,Serck-Hanssen G

更新日期：1975-02-28 00:00:00

abstract：:Oxidation of semiquinone by O2 in the Q cycle is known to be one of the sources of superoxide anion (O2.-) in aerobic cells. In this paper, such a phenomenon was analyzed using the chemical kinetics model of electron transfer from succinate to cytochrome c, including coenzyme Q, the complex III non-heme iron protein F...

journal_title：Molecular and cellular biochemistry

authors： Demin OV,Kholodenko BN,Skulachev VP

更新日期：1998-07-01 00:00:00

abstract：:In this work we investigated the effects of retinoic acid (RA) in Sertoli cells. Sertoli cells isolated from 15-day-old Wistar rats were previously cultured for 48 h and then treated with RA for 24 h. RA at high doses (1-10 microM) increased TBARS levels and induced a decrease in cell viability. At low doses (0.1-100 ...

journal_title：Molecular and cellular biochemistry

authors： Conte da Frota ML Jr,Gomes da Silva E,Behr GA,Roberto de Oliveira M,Dal-Pizzol F,Klamt F,Moreira JC

更新日期：2006-04-01 00:00:00

abstract：:Chronic aristolochic acid (AA) nephropathy (CAAN) caused by intake of AA-containing herbs is difficult to treat. We evaluated the therapeutic effect of bone marrow (BM) mesenchymal stem cells (MSCs) on a rat model of CAAN. Female Wistar rats were fed with decoction of Caulis Aristolochia manshuriensis by intragastric ...

journal_title：Molecular and cellular biochemistry

authors： Li W,Jiang H,Feng JM

更新日期：2012-09-01 00:00:00

abstract：:Plexiform neurofibromas commonly found in patients with Neurofibromatosis type I (NF1) have a 5% risk of being transformed into malignant peripheral nerve sheath tumors (MPNST). Germline mutations in the NF1 gene coding for neurofibromin, which is a Ras GTPase activating protein (RasGAP) and a negative regulator of Ra...

journal_title：Molecular and cellular biochemistry

authors： Kraniak JM,Sun D,Mattingly RR,Reiners JJ Jr,Tainsky MA

更新日期：2010-11-01 00:00:00

abstract：:Chronic exposure to many heavy metals and metal-derivatives is associated with an increased risk of cancer, although the mechanisms of tumorigenesis are largely unknown. Approximately 125 scientists attended the 3rd Conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis and presented the latest resear...

journal_title：Molecular and cellular biochemistry

authors： Bower JJ,Leonard SS,Shi X

更新日期：2005-11-01 00:00:00

abstract：:MicroRNAs (miRNAs) are a class of non-coding small RNAs. They play an important role as a post-transcriptional regulator in the protein synthesis and are involved in cellular processes, such as proliferation, apoptosis, and differentiation. miRNAs give us a new perspective to understand carcinogenesis. Since the high-...

journal_title：Molecular and cellular biochemistry

authors： Xie L,Qian X,Liu B

更新日期：2010-08-01 00:00:00