Energy metabolism of isolated rat thymus cells.

abstract：:Antecedent studies have suggested that lipid composition and fluidity of cellular membranes of various organs are altered in response to thyroid hormone status. To date, the effects of thyroid hormone status on these parameters have not been examined in rat renal apical membrane in regard to sodium-dependent phosphate...

journal_title：Molecular and cellular biochemistry

authors： Prasad R,Kumar V

更新日期：2005-01-01 00:00:00

abstract：:The continuous advancements in cancer research have contributed to the overwhelming evidence of the presence of telomerase in primary and secondary tumours together with hsp90 and c-Myc. This review will discuss the important role of telomerase together with hsp90 and c-Myc within the initiation and progression of gli...

journal_title：Molecular and cellular biochemistry

authors： Shervington A,Cruickshanks N,Wright H,Atkinson-Dell R,Lea R,Roberts G,Shervington L

更新日期：2006-02-01 00:00:00

abstract：:Silkworm (Bombyx mori) is not only a model organism for scientific studies, but also a commercial insect for agricultural production. BmAtg8 (a B. mori homolog of yeast Atg8) plays crucial roles in macroautophagy (hereafter referred to autophagy), which is helpful for silkworm metamorphosis. Relevant mechanism about B...

journal_title：Molecular and cellular biochemistry

authors： Xue S,Mao F,Hu D,Yan H,Lei J,Obeng E,Zhou Y,Quan Y,Yu W

更新日期：2019-07-01 00:00:00

abstract：:In vivo administration of pyridine has been shown to increase the activity and content of several forms of cytochrome P450 by transcriptional and posttranscriptional mechanisms. The effect of pyridine on CYP1A and CYP2E1 isozymes was studied in a rat hepatocyte culture model. Hepatocytes were isolated from non-induced...

journal_title：Molecular and cellular biochemistry

authors： Wu D,Ramin SA,Cederbaum AI

更新日期：1997-08-01 00:00:00

abstract：:Henna leaf (Lawsonia inermis), commonly known as Mehndi is cultivated throughout India and is a very popular natural dye to color hand and hair. It is an integral part of indigenous culture, and is also known for its medicinal value. The effect of 200 and 400 mg/kg body weight of 80% ethanolic extract of the fresh lea...

journal_title：Molecular and cellular biochemistry

authors： Dasgupta T,Rao AR,Yadava PK

更新日期：2003-03-01 00:00:00

abstract：:Interactions of cytochrome P450 2B1 were probed using 8-anilino-1-naphthalenesulfonic acid (ANS), a well known and frequently used reporter group for hydrophobic interactions. Titration of cytochrome P450 2B1 with ANS revealed 6.6 +/- 0.2 ANS binding sites per molecule of P450 2B1 with a Kd value of 42 +/- 2 microM. I...

journal_title：Molecular and cellular biochemistry

authors： Yu XC,Strobel HW

更新日期：1996-09-20 00:00:00

abstract：:Lipoamidase is found to be able to release various membrane-anchored enzymes from the membrane compartment of pig brain. Released enzymes revealed their intact enzyme activities in the soluble fraction. Lipoamidase could release at least two types of anchored enzymes, i.e. glycosyl-phosphatidylinositol-bonded and myri...

journal_title：Molecular and cellular biochemistry

authors： Oizumi J,Hayakawa K

更新日期：1992-09-22 00:00:00

abstract：:Twigs-dry leaves smoke condensate (TDS) was investigated for its DNA damaging activity in human peripheral lymphocytes, by using a sensitive method, fluorescence analysis of DNA unwinding (FADU). An aqueous turmeric component (Aq.T) was studied as a protective agent. TDS at one to 100 folds dilution induced 55% DNA da...

journal_title：Molecular and cellular biochemistry

authors： Shalini VK,Srinivas L

更新日期：1990-06-01 00:00:00

abstract：:Control of mitochondrial respiration depends on ADP availability to the F1-ATPase. An electrochemical gradient of ADP and ATP across the mitochondrial inner membrane is maintained by the adenine nucleotide translocase which provides ADP to the matrix for ATP synthesis and ATP for energy-dependent processes in the cyto...

journal_title：Molecular and cellular biochemistry

authors： McMillin JB,Pauly DF

更新日期：1988-06-01 00:00:00

abstract：:A quarter of the human population with European background carries at least one allele of the OPRD1 gene that encodes the delta opioid receptor with cysteine at the amino acid position 27 (hδOR(Cys27)) instead of the evolutionary conserved phenylalanine (hδOR(Phe27)). The two variants have indistinguishable pharmacolo...

journal_title：Molecular and cellular biochemistry

authors： Tuusa JT,Petäjä-Repo UE

更新日期：2011-05-01 00:00:00

abstract：:The contractile hyporesponsiveness of the streptozotocin diabetic rat heart in vitro to beta-adrenergic agonists is eliminated when the heart is perfused with N(G)-nitro-L-arginine methyl ester (L-NAME), a non-selective inhibitor of nitric oxide synthase (NOS). The following study evaluated the hypothesis that an incr...

journal_title：Molecular and cellular biochemistry

authors： Smith JM,Sondgeroth KB,Wahler GM

更新日期：2007-06-01 00:00:00

abstract：:Thioredoxin (Trx) is a small ubiquitous protein, which has been shown to be involved in redox-dependent cellular functions. In this article, we demonstrate that the increased level of Trx induces AP-1 DNA binding in a redox-dependent manner by activating JNK subgroup of MAPKs. The majority of AP-1 DNA binding complex ...

journal_title：Molecular and cellular biochemistry

authors： Das KC,Muniyappa H

更新日期：2010-04-01 00:00:00

abstract：:Well-documented evidence suggests that environmental and occupational exposure of toxic metals or metal-containing compounds can cause a number of human diseases, including inflammation and cancer, through DNA damage, protein modifications, or lipid peroxidation. This mini-review addresses the mechanisms of cell death...

journal_title：Molecular and cellular biochemistry

authors： Chen F,Vallyathan V,Castranova V,Shi X

更新日期：2001-06-01 00:00:00

abstract：:We investigated the expression of the nuclear-encoded genes controlling the mitochondrial properties in the mouse gastrocnemius muscle to gain insight into the mitochondrial biogenesis that occurs during the muscle degeneration/regeneration induced by freezing. In addition, we tested whether the muscle regeneration is...

journal_title：Molecular and cellular biochemistry

authors： Wagatsuma A,Kotake N,Yamada S

更新日期：2011-03-01 00:00:00

abstract：:Genistein is often used as an inhibitor of tyrosine kinases. A less studied side effect of genistein is an inhibition of cyclic AMP-phosphodiesterase (cAMP-PDE) activity resulting in increased cAMP accumulation. The effect of genistein on intracellular cAMP-levels, basal and forskolin-induced, was studied in A549 huma...

journal_title：Molecular and cellular biochemistry

authors： Burvall KM,Palmberg L,Larsson K

更新日期：2002-11-01 00:00:00

abstract：:Free fatty acids (FFA)-induced proliferation and apoptosis was studied in human umbilical vein endothelial cells (HUVECs). A recombinant adenovirus containing a RNAi cassette targeting the GSK-3beta gene was produced and its silencing effect on GSK-3beta gene was detected by Western blot analysis and immunohistochemis...

journal_title：Molecular and cellular biochemistry

authors： Zhu P,Chen G,You T,Yao J,Jiang Q,Lin X,Shen X,Qiao Y,Lin L

更新日期：2010-05-01 00:00:00

abstract：:The genome sequence of Mycobacterium tuberculosis revealed the presence of several hydrolases involved in lipid metabolism including the members of Lip gene family. Rv0646c (LipG) is one of them. It is annotated as putative esterase/lipase because of the presence of consensus sequence 'GXSXG.' The gene was cloned, exp...

journal_title：Molecular and cellular biochemistry

authors： Rastogi R,Kumar A,Kaur J,Saini V,Kaur J,Bhatnagar A

更新日期：2018-10-01 00:00:00

abstract：:Hepatic stellate cells (HSCs) play an important role in the development of hepatic fibrosis. Heat shock protein 90 (Hsp90) is essential for the maturation and activity of a varied group of proteins involved in signal transduction and cell cycle regulation. In this study, we found that two Hsp90 inhibitors, VER-49009 a...

journal_title：Molecular and cellular biochemistry

authors： Sun X,Zhang XD,Cheng G,Hu YH,Wang HY

更新日期：2009-10-01 00:00:00

abstract：:The effects of 8-week diethylmaleate (DEM) and clofibric acid (CFA) supplemented diet on blood pressure, body and liver weights, liver antioxidant status and nitric oxide synthase (NOS) activity were investigated in 8-week DOCA-salt treated and untreated Sprague-Dawley male rats. It appeared that DEM and particularly ...

journal_title：Molecular and cellular biochemistry

authors： Nicod L,Rodriguez S,Jacqueson A,Viollon-Abadie C,Berthelot A,Richert L

更新日期：2000-10-01 00:00:00

abstract：:Production of human papillomavirus type 16 major capsid protein L1 in undifferentiated cells is negatively regulated by several yet unidentified cis-acting inhibitory RNA elements, among which a major element is located within the first 514 nucleotides of the L1-mRNA. By Northern blotting we examined effect of the maj...

journal_title：Molecular and cellular biochemistry

authors： Mori S,Ozaki S,Yasugi T,Yoshikawa H,Taketani Y,Kanda T

更新日期：2006-08-01 00:00:00

abstract：:Prion protein (PrP) interacts with some kringle domain-containing proteins. Kringle domains serve as binding domains in the interaction with PrP. The structural conservation among kringle domains leads to the hypothesis that any protein containing these domains can interact with PrP and be involved in prion pathogenes...

journal_title：Molecular and cellular biochemistry

authors： Kim Y,Song J,Mays CE,Titlow W,Yoon D,Ryou C

更新日期：2009-08-01 00:00:00

abstract：:Ionizing radiation induces apoptosis in human Molt-4 leukemia cells in a p53-dependent manner. The tumor suppressor p53 stimulates various downstream targets that presumably trigger, individually or in concert, de novo ceramide synthesis and intrinsic apoptosis via mitochondrial outer membrane permeabilization (MOMP)....

journal_title：Molecular and cellular biochemistry

authors： Kobeissy H,Hage-Sleiman R,Dakdouk Z,Kozhaya L,Dbaibo G

更新日期：2020-12-01 00:00:00

abstract：:The present study was designed to induce massive accumulation of calcium in the myocardium and to evaluate the effect of calcium overload on myocardial contractile function and biochemical activity of cardiac subcellular membranes. Rats were treated with an oral administration of 500,000 units/kg of vitamin D3 for 3 c...

journal_title：Molecular and cellular biochemistry

authors： Takeo S,Tanonaka R,Tanonaka K,Miyake K,Hisayama H,Ueda N,Kawakami K,Tsumura H,Katsushika S,Taniguchi Y

更新日期：1991-10-16 00:00:00

abstract：:Ventricular electrical conduction has been investigated in the streptozotocin (STZ)-induced diabetic rat. Diabetes was induced with a single injection of STZ (60 mg/kg bodyweight, ip). The ECG was measured continuously, in vivo, using a biotelemetry system. Left ventricular action potentials were recorded with an extr...

journal_title：Molecular and cellular biochemistry

authors： Howarth FC,Jacobson M,Qureshi MA,Shafiullah M,Hameed RS,Zilahi E,Al Haj A,Nowotny N,Adeghate E

更新日期：2009-08-01 00:00:00

abstract：:Accumulating data have shown that microRNAs are involved in the pathogenesis of cancer. miR-202 has been confirmed to be downregulated in several types of human cancer. However, the expression and biological role of miR-202 in osteosarcoma (OS) carcinogenesis and progression remain unclear. In this study, we demonstra...

journal_title：Molecular and cellular biochemistry

authors： Sun Z,Zhang T,Hong H,Liu Q,Zhang H

更新日期：2014-12-01 00:00:00

abstract：:Methylxanthines are widely consumed because of their stimulating effect primarily on the central nervous system. Their diuretic and respiratory stimulant action is used in clinical medicine. L-Arginine metabolism in the brain is very important for normal brain function. In addition to brain protein synthesis, arginine...

journal_title：Molecular and cellular biochemistry

authors： Nikolic J,Bjelakovic G,Stojanovic I

更新日期：2003-02-01 00:00:00

abstract：:In the present study it was investigated if Vitamin A supplementation could protect rat kidney microsomes and mitochondria from in vitro lipoperoxidation. After incubation of rat kidney microsomes and mitochondria in an ascorbate-Fe+2 system, at 37 degrees C during 60 min, it was observed that the total cpm/mg protein...

journal_title：Molecular and cellular biochemistry

authors： Piergiacomi VA,Palacios A,Catalá A

更新日期：1996-12-20 00:00:00

abstract：:The present study was aimed to investigate the protective effects of 17β-estradiol (E2) and estrogen receptor α (ERα) on isoproterenol (ISO)-treated H9c2 cardiomyoblast cells. In the present study, we treated H9c2 cells with ISO, a β-adrenergic receptor agonist, to induce myocardiac hypertrophy. Pre-administration of ...

journal_title：Molecular and cellular biochemistry

authors： Pai P,Velmurugan BK,Kuo CH,Yen CY,Ho TJ,Lin YM,Chen YF,Lai CH,Day CH,Huang CY

更新日期：2017-10-01 00:00:00

abstract：:Recent evidence indicated that endocan may be a potential cell marker and a new target for cancers including acute leukemia since the serum endocan level in patients with acute leukemia was associated with the status of the disease, i.e., endocan was higly expressed in untreated acute leukemia, but decreased after che...

journal_title：Molecular and cellular biochemistry

authors： Xu Z,Zhang S,Zhou Q,Wang Y,Xia R

更新日期：2014-10-01 00:00:00

abstract：:In order to explore the role of cytochrome P-450 (CYP) 2E1 in schisandrin B (Sch B)-induced antioxidant and heat shock responses, the effects of Sch B treatment on hepatic mitochondrial glutathione antioxidant status (mtGAS) and heat shock protein (Hsp)25/70 expression were compared between wild-type and cyp2e1 knock-...

journal_title：Molecular and cellular biochemistry

authors： Chiu PY,Leung HY,Poon MK,Lee SS,Ko KM

更新日期：2006-12-01 00:00:00