Evaluation of SAT-1, SAT-2 and GalNAcT-1 mRNA in colon cancer by real-time PCR.

abstract：:Cisplatin is a widely used antineoplastic agent in the treatment of head and neck cancer. However, it is highly nephrotoxic. Oxidative stress is the main mechanism responsible for cisplatin-induced nephrotoxicity. The aim of this study was to characterize cisplatin-induced nephrotoxicity, oxidative stress in periphera...

journal_title：Molecular and cellular biochemistry

authors： Quintanilha JCF,Visacri MB,Sousa VM,Bastos LB,Vaz CO,Guarnieri JPO,Amaral LS,Malaguti C,Lima CSP,Vercesi AE,Moriel P

更新日期：2018-03-01 00:00:00

abstract：:Hypoxia impairs the muscle fibre-type shift from fast-to-slow during post-natal development; however, this adaptation could be a consequence of the reduced voluntary physical activity associated with hypoxia exposure rather than the result of hypoxia per se. Moreover, muscle oxidative capacity could be reduced in hypo...

journal_title：Molecular and cellular biochemistry

authors： Chaillou T,Koulmann N,Meunier A,Chapot R,Serrurier B,Beaudry M,Bigard X

更新日期：2014-05-01 00:00:00

abstract：:Pregna-D'-pentaranes (pentaranes) are modified progesterones with demonstrable progestational activity and contraceptive effect. We have examined the steroid binding characteristics of the two newly synthesized progesterone analogs, Pentarane A (16 alpha, 17 alpha-cyclohexanoprogesterone) and Pentarane B (6 alpha-meth...

journal_title：Molecular and cellular biochemistry

authors： Bhakta A,Herman M,Levina IS,Moudgil VK

更新日期：1993-08-25 00:00:00

abstract：:A high molecular weight protein has been isolated as a major polypeptide comprising 85% of the total extractable proteins in the fruit pericarp of the plant Impatiens balsamina. The protein has been purified to homogeneity following fractionation of the crude cell supernatant with ammonium sulphate, chromatography on ...

journal_title：Molecular and cellular biochemistry

authors： Pal M,Biswas S

更新日期：1994-01-26 00:00:00

abstract：:We measured the relative sliding velocity of cardiomyopathic hamster cardiac myosin on actin cables by using an in vitro motility assay system. We also investigated the relationship between the velocity and both myosin isozyme content and ATPase activity. Cardiac myosin was obtained from cardiomyopathic hamsters (BIO ...

journal_title：Molecular and cellular biochemistry

authors： Yamashita H,Sugiura S,Sata M,Serizawa T,Iizuka M,Shimmen T,Momomura S

更新日期：1993-02-17 00:00:00

abstract：:Ovarian cancer has the highest mortality in gynecologic malignancies. LncRNA BLACAT1 serves crucial functions in various cancers, but its role in ovarian cancer has not been investigated. In this article, our team explored the role and the potential regulatory mechanism of BLACAT1 in ovarian cancer. Quantitative RT-PC...

journal_title：Molecular and cellular biochemistry

authors： Yang H,Qi Y,Wang XL,Gu JJ,Shi TM

更新日期：2020-04-01 00:00:00

abstract：:MicroRNAs play critical roles in the development and progression of non-small cell lung cancer (NSCLC). miR-96 acts as an oncogene in some malignancies, while its role in NSCLC is unclear. Here, we validated that miR-96 was significantly increased in both human NSCLC tissues and cell lines. Inhibition of miR-96 expres...

journal_title：Molecular and cellular biochemistry

authors： Guo H,Li Q,Li W,Zheng T,Zhao S,Liu Z

更新日期：2014-05-01 00:00:00

abstract：:Winter survival for many insect species relies on the ability to endure the freezing of extracellular body fluids. Because freezing impedes oxygen delivery to tissues, one component of natural freeze tolerance is a well-developed anoxia/ischemia resistance. The present study explores the responses of the hypoxia-induc...

journal_title：Molecular and cellular biochemistry

authors： Morin P Jr,McMullen DC,Storey KB

更新日期：2005-12-01 00:00:00

abstract：:Hepatocyte cell adhesion molecule (HepaCAM) plays a crucial role in tumor progression and has been recognized as a novel tumor suppressor gene. The high protein expression level of protein kinase Cε (PKCε) has been discovered in many tumor types. In the present study, we determined HepaCAM and PKCε protein levels in h...

journal_title：Molecular and cellular biochemistry

authors： Tan B,Tan J,Du H,Quan Z,Xu X,Jiang X,Luo C,Wu X

更新日期：2014-06-01 00:00:00

abstract：:The effects of different dietary fats on peritoneal macrophage plasma membrane fluidity, intracellular cyclic AMP (cAMP) production, GTP hydrolysis and TNF binding and TNF-induced IL1 and IL6 production was investigated. After a four week period, fluidity, as determined by both fluorescence recovery after photobleachi...

journal_title：Molecular and cellular biochemistry

authors： Tappia PS,Ladha S,Clark DC,Grimble RF

更新日期：1997-01-01 00:00:00

abstract：:Rat pheochromocytoma PC12 cells have been treated with nerve growth factor (NGF) at final concentrations of 2, 4, 8, and 16 ng/ml, and then were exposed to 60-Hz, sinusoidal magnetic fields (MF) of 12.5, 25, 50, and 100 microT (rms) for 30 min. Transcript levels for both c-fos and glyceraldehyde-3 -phosphate dehydroge...

journal_title：Molecular and cellular biochemistry

authors： Campbell-Beachler M,Ishida-Jones T,Haggren W,Phillips JL

更新日期：1998-12-01 00:00:00

abstract：:Evidence suggests that endothelial cell layer heparan sulfate proteoglycans include a variety of different sized molecules which most likely contain different protein cores. In the present report, approximately half of endothelial cell surface associated heparan sulfate proteoglycan is shown to be releasable with solu...

journal_title：Molecular and cellular biochemistry

authors： Lowe-Krentz LJ,Thompson K,Patton WA 2nd

更新日期：1992-01-15 00:00:00

abstract：:The aim of this study was to investigate estrogen's effect on age-related changes in bladder function. Female Wistar rats were divided into three groups that included young rats (3-month-old) (YR), old rats (13-month-old) (OR), and old rats given subcutaneous treatments of estradiol for 6 weeks (OR + E). The groups we...

journal_title：Molecular and cellular biochemistry

authors： Watanabe T,Matsumoto M,Toji S,Miyagawa I

更新日期：2008-11-01 00:00:00

abstract：:Chromium(VI) [Cr(VI)] induces chronic inflammation in hepatocytes. Inflammation has been shown to play an important role in tumorigenesis, tumor progression, and metastasis. To examine the effects of the Styrax Japonica Siebold et al. Zuccarini (SJSZ) glycoprotein on inflammation in BNL CL.2 cells, we evaluated the ac...

journal_title：Molecular and cellular biochemistry

authors： Lee J,Lim KT

更新日期：2012-08-01 00:00:00

abstract：:Mucus hypersecretion is a major manifestation in patients with chronic inflammatory airway diseases, and MUC5AC protein is a major component of airway mucus. Earlier studies have demonstrated that neutrophil elastase (NE), a serine protease, mainly produced by neutrophils, stimulates the production of MUC5AC from airw...

journal_title：Molecular and cellular biochemistry

authors： Zhong T,Perelman JM,Kolosov VP,Zhou XD

更新日期：2011-12-01 00:00:00

abstract：:In the eluted fractions of histone-treated crude extracts separated by Sephadex G-200 filtration, multiple protein kinase (PK) activities, including three from brain and two from skeletal muscle, were augmented by both S-100 protein and parvalbumin on the phosphorylation of endogenous substrates. One additional PK act...

journal_title：Molecular and cellular biochemistry

authors： Kuo WN,Blake T,Cheema IR,Dominguez J,Nicholson J,Puente K,Shells P,Lowery J

更新日期：1986-06-01 00:00:00

abstract：:The molecular signaling events leading to protection from oxidative stress-induced apoptosis upon contact inhibition have not been fully investigated. Previous research has indicated a role for mitogen-activated protein kinases (MAPKs) in the regulation of contact inhibition, and these proteins have also been associat...

journal_title：Molecular and cellular biochemistry

authors： Gaballah M,Slisz M,Hutter-Lobo D

更新日期：2012-01-01 00:00:00

abstract：:Changes in fatty acid composition of myocardial lipids were examined in rats with heart failure following myocardial infarction. Left ventricular systolic pressure (LVSP) was decreased and left ventricular end-diastolic pressure (LVEDP) was elevated 24 h, 1 and 12 weeks after left coronary artery ligation (CAL), sugge...

journal_title：Molecular and cellular biochemistry

authors： Nasa Y,Sakamoto Y,Sanbe A,Sasaki H,Yamaguchi F,Takeo S

更新日期：1997-11-01 00:00:00

abstract：:To evaluate the effects of the in vivo endotoxin treatment of the rat on (1) the contractile responses in the subsequently isolated papillary muscle to adrenergic and cholinergic agonists and (2) the biochemical parameters (cyclic GMP, nitric oxide synthesis, protein phosphorylation and ADP-ribosyslation) in the subse...

journal_title：Molecular and cellular biochemistry

authors： Sulakhe PV,Sandirasegarane L,Davis JP,Vo XT,Costain WJ,Mainra RR

更新日期：1996-10-01 00:00:00

abstract：:Failure in obtaining expression of functional adrenocorticotropic hormone receptor (ACTHR, or melanocortin 2 receptor, MC2R) in non-adrenal cells has hindered molecular analysis of ACTH signaling pathways. Here, we ectopically expressed the mouse ACTHR in Balb/c mouse 3T3 fibroblasts to analyze ACTH signaling pathways...

journal_title：Molecular and cellular biochemistry

authors： Forti FL,Dias MH,Armelin HA

更新日期：2006-12-01 00:00:00

abstract：:Existing kinetic data of cholesteryl ester formation by lecithin:cholesterol acyltransferase in discoidal high-density lipoproteins with 34 mutations of apoA-I that involved all putative helices were grouped by cluster analysis into four noncoincident regions with mutations both without any functional impairment and w...

journal_title：Molecular and cellular biochemistry

authors： Dergunov AD

更新日期：2013-06-01 00:00:00

abstract：:The inhibitory effect of menaquinone-7 (MK-7; vitamin K2) on osteoclast-like cell formation and osteoclastic bone resorption in vitro is found (Mol Cell Biochem 228: 39-47, 2001). This study, furthermore, was undertaken to determine the effect of MK-7 on the bone-resorbing factor-induced bone resorption using the femo...

journal_title：Molecular and cellular biochemistry

authors： Yamaguchi M,Uchiyama S,Tsukamoto Y

更新日期：2003-03-01 00:00:00

abstract：:Incubation of Clone 9 cells, a nontransformed rat liver cell line, in the presence of 5 mM azide results in an induction of GLUT1 mRNA which becomes detectable after approximately 3 h of continuous exposure to the agent. In examining the role of on-going protein synthesis in this response, we found that: (i) the induc...

journal_title：Molecular and cellular biochemistry

authors： Behrooz A,Ismail-Beigi F

更新日期：1998-10-01 00:00:00

abstract：:Tyrosine hydroxylase is considered to be the rate-limiting enzyme in the synthesis of catecholamines in both the central and peripheral nervous system. Increased or decreased neuronal activity, stress, lesions, drug effects, endocrinological manipulations and experimental models of hypertension are associated with alt...

journal_title：Molecular and cellular biochemistry

authors： Masserano JM,Weiner N

更新日期：1983-01-01 00:00:00

abstract：:Expression of ErbB4 receptor is correlated with the incidence of non-metastatic types of human cancers, whereas the overexpression of other ErbB receptor families (ErbB1/EGFR, ErbB2 and ErbB3) is correlated to the formation of metastatic tumors. However, the molecular mechanism underlying this phenomenon has been uncl...

journal_title：Molecular and cellular biochemistry

authors： Yumoto N,Yu X,Hatakeyama M

更新日期：2006-04-01 00:00:00

abstract：:Shin et al. (Biochim Biophys Acta 444: 794-801, 1976) described the subcellular location of [3H]folic acid after injection into rats. The microsomal fraction of the liver contained relatively large amounts of tracer initially but lower amounts at later times. Because of the heterogeneous nature of the microsomal fract...

journal_title：Molecular and cellular biochemistry

authors： Brody T,Stokstad EL

更新日期：1990-09-03 00:00:00

abstract：:Protein phosphorylation was investigated in [32P]-labeled cardiomyocytes isolated from adult rat heart ventricles. The beta-adrenergic stimulation (by isoproterenol, ISO) increased the phosphorylation of inhibitory subunit of troponin (TN-I), C-protein and phospholamban (PLN). Such stimulation was largely mediated by ...

journal_title：Molecular and cellular biochemistry

authors： Sulakhe PV,Vo XT

更新日期：1995-08-01 00:00:00

abstract：:Poly(ADP-ribose) polymerases or PARPs are a family of NAD(+)-dependent enzymes that modify themselves and other substrate proteins with ADP-ribose polymers. The founding member PARP 1 is localized predominantly in the nucleus and is activated by binding to DNA lesions. Excessive PARP 1 activation following genotoxin t...

journal_title：Molecular and cellular biochemistry

authors： Yeh TY,Sbodio JI,Nguyen MT,Meyer TN,Lee RM,Chi NW

更新日期：2005-08-01 00:00:00

abstract：:It has been recently hypothesized that in PIH a placental oxidant-antioxidant imbalance might cause the release of lipoperoxidation products into the circulation, with subsequent damage of endothelial cell membranes. In this hypothesis the endothelial cell and further increase in circulating lipoperoxide levels, which...

journal_title：Molecular and cellular biochemistry

authors： Cester N,Staffolani R,Rabini RA,Magnanelli R,Salvolini E,Galassi R,Mazzanti L,Romanini C

更新日期：1994-02-23 00:00:00

abstract：:We assessed whether aging augments left ventricular (LV) damage, remodeling, and dysfunction and alters expression of healing-specific-matricellular proteins (HSMPs), matrix metalloproteinases (MMPs) and other pertinent proteins after acute reperfused-ST-segment-elevation myocardial infarction (RSTEMI) in the dog mode...

journal_title：Molecular and cellular biochemistry

authors： Jugdutt BI,Palaniyappan A,Uwiera RR,Idikio H

更新日期：2009-02-01 00:00:00