Inhibitory effect of menaquinone-7 (vitamin K2) on the bone-resorbing factors-induced bone resorption in elderly female rat femoral tissues in vitro.

abstract：:The effect of ginsenoside Rg1 (Rg1) on hepatic damage caused by concanavalin A (Con A) has not been fully elucidated. This study was designed to evaluate the protective effect of Rg1 on Con A-induced hepatitis in mice and explore the potential mechanisms of this effect. C57BL/6 mice were divided randomly into the foll...

journal_title：Molecular and cellular biochemistry

authors： Cao L,Zou Y,Zhu J,Fan X,Li J

更新日期：2013-08-01 00:00:00

abstract：:The exchange of protons and deuterons by phosphoglucoisomerase during the single passage conversion of D-[2-13C,1-2H]fructose 6-phosphate in H2O or D-[2-13C]fructose 6-phosphate in D2O to D-[2-13C]glucose 6-phosphate, as coupled with the further generation of 6-phospho-D-[2-13C]gluconate in the presence of excess gluc...

journal_title：Molecular and cellular biochemistry

authors： Malaisse WJ,Liemans V,Malaisse-Lagae F,Ottinger R,Willem R

更新日期：1991-05-15 00:00:00

abstract：:Microtubule-associated proteins (MAPs) interact with tubulin in vitro and in vivo. Despite that there is a large amount of information on the roles of these proteins in neurons, the data on non-neuronal MAPs or MAPs-related proteins is scarce. There is an increasing number of microtubule-interacting proteins that have...

journal_title：Molecular and cellular biochemistry

authors： Vial C,Armas-Portela R,Avila J,González M,Maccioni RB

更新日期：1995-03-23 00:00:00

abstract：:Y-box binding protein-1 (YB-1), a member of Y-box protein family binding DNA and RNA, has been proposed as a novel marker in multiple malignant tumors and found to be associated with tumor malignancy. Neuroblastoma is an embryonal tumor arising from neuroblast cells of the autonomic nervous system, which is the most c...

journal_title：Molecular and cellular biochemistry

authors： Wang H,Sun R,Chi Z,Li S,Hao L

更新日期：2017-09-01 00:00:00

abstract：:The OCT4 transcription factor is a crucial stem cells marker and it has been related to the cancer stem cells concept. Moreover, it has also been associated to the multiple drug resistance (MDR) phenotype. Our first results pointed out a straight relation between OCT4 and ABC transporters in K562-derivative MDR (Lucen...

journal_title：Molecular and cellular biochemistry

authors： Oliveira BR,Figueiredo MA,Trindade GS,Marins LF

更新日期：2015-02-01 00:00:00

abstract：:The interaction of deferiprone (1,2-dimethyl-3-hydroxy-pyrid-4-one) L1, the first clinically available oral iron chelator, with the tetrameric allosteric protein hemoglobin from human red blood cells has been investigated spectrofluorometrically and by circular dichroism spectroscopy. The interaction is hydrogenbond l...

journal_title：Molecular and cellular biochemistry

authors： Chakraborty D,Bhattacharyya M

更新日期：2000-01-01 00:00:00

abstract：:Pre-steady-state and steady-state kinetics for the p.p. elastase-catalysed hydrolysis of ZAlaONp, one of the most favourable substrates for this serine protease, have been studied between pH 4.0 and 8.0. The results are consistent with the minimum three-step mechanism: (formula; see text) Under pre-steady-state condit...

journal_title：Molecular and cellular biochemistry

authors： Ascenzi P,Menegatti E,Guarneri M,Antonini E

更新日期：1983-01-01 00:00:00

abstract：:Sinomenine, a pure alkaloid extract from Sinomenium acutum, has anti-inflammatory and immunoregulatory functions. This study investigated the efficiency and the signalling pathways involved in the effect of sinomenine on vascular smooth muscle cell (VSMC) dedifferentiation in response to platelet-derived growth factor...

journal_title：Molecular and cellular biochemistry

authors： Zhu L,Hao Y,Guan H,Cui C,Tian S,Yang D,Wang X,Zhang S,Wang L,Jiang H

更新日期：2013-01-01 00:00:00

abstract：:Glioblastoma is the most common and deadly type of brain cancer. The poor prognosis may be largely attributed to inadequate disease response to current chemotherapeutic agents. Activation of p38 is associated with deleterious outcomes in glioblastoma patients, as its signaling mediates chemoresistance mechanisms. Anti...

journal_title：Molecular and cellular biochemistry

authors： Su BC,Chen JY

更新日期：2020-01-01 00:00:00

abstract：:Cardiac myocytes proliferate most rapidly during the hyperplastic phase of heart development; however, the level of cell cycle activity is drastically down regulated after birth. Further growth of the heart is achieved by hypertrophic growth of cardiac myocytes. The mechanism that controls the switch from hyperplastic...

journal_title：Molecular and cellular biochemistry

authors： Evans HJ,Goodwin RL

更新日期：2007-09-01 00:00:00

abstract：:Partially purified D-aspartate oxidase from beef kidney has been tested in the presence of butanedione or phenylglyoxal, which specifically modify the arginine molecule. The results obtained clearly indicate that arginine residues are involved in the binding of the substrate to the active site of the enzyme. ...

journal_title：Molecular and cellular biochemistry

authors： Crifò C,Santoro L,Rinaldi A,De Marco C

更新日期：1977-08-19 00:00:00

abstract：:The present study was aimed to get the nucleotide sequences of a part of COII mitochondrial gene amplified from individuals of five species of Termites (Isoptera: Termitidae: Macrotermitinae). Four of them belonged to the genus Odontotermes (O. obesus, O. horni, O. bhagwatii and Odontotermes sp.) and one to Microterme...

journal_title：Molecular and cellular biochemistry

authors： Sobti RC,Kumari M,Sharma VL,Sodhi M,Mukesh M,Shouche Y

更新日期：2009-11-01 00:00:00

abstract：:The interaction of immune cells with endothelial and target cells and extracellular matrix in human organ transplants is regulated by a number of receptor-ligand molecules. The molecules mediating intercellular adhesion and activation are classified as integrin, immunoglobulin and selectin families. In the present stu...

journal_title：Molecular and cellular biochemistry

authors： Steinhoff G,Haverich A

更新日期：1995-06-07 00:00:00

abstract：:The rat uterine secretory enzyme glycerylphosphorylcholine (GPC) diesterase (EC 3.1.4.2) had been purified and characterized previously with respect to its mol. wt., size, amino acid, carbohydrate composition and estrogen inducible properties. This enzyme is observed to have exclusive specificity for GPC and exhibits ...

journal_title：Molecular and cellular biochemistry

authors： Mitra J,Chowdhury M

更新日期：1994-10-26 00:00:00

abstract：:Cross-talk between coding RNAs and regulatory non-coding microRNAs, within human genome, has provided compelling evidence for the existence of flexible checkpoint control of T-Cell activation. The present study attempts to demonstrate that the interplay between miR-2909 and its effector KLF4 gene has the inherent capa...

journal_title：Molecular and cellular biochemistry

authors： Kaul D,Malik D,Wani S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We reported that urinary L-FABP reflected the progression of chronic kidney disease (CKD). This study is aimed to evaluate the clinical significance of urinary liver type fatty acid binding protein (L-FABP) as a biomarker for monitoring CKD. METHODS:Urinary L-FABP was measured using human L-FABP ELISA kit (...

journal_title：Molecular and cellular biochemistry

authors： Kamijo A,Sugaya T,Hikawa A,Yamanouchi M,Hirata Y,Ishimitsu T,Numabe A,Takagi M,Hayakawa H,Tabei F,Sugimoto T,Mise N,Omata M,Kimura K

更新日期：2006-03-01 00:00:00

abstract：:Long-chain fatty acids (e.g. arachidonic acid) have been implicated in physiological control of insulin secretion. We previously reported histidine phosphorylation of at least two islet proteins (e.g., NDP kinase and the beta subunit of trimeric G-proteins), and suggested that such a signalling step may have regulator...

journal_title：Molecular and cellular biochemistry

authors： Kowluru A

更新日期：2004-11-01 00:00:00

abstract：:The T-786C, Glu298Asp, and 27 bp variable number of tandem repeats (27 bp-VNTR-a/b) polymorphsims of the endothelial nitric oxide synthase (eNOS) gene are thought to alter nitric oxide production and contribute to the development of vascular and renal disease risk. The objective of this study is to investigate whether...

journal_title：Molecular and cellular biochemistry

authors： Nath SD,He X,Voruganti VS,Blangero J,MacCluer JW,Comuzzie AG,Arar NH,Abboud HE,Thameem F

更新日期：2009-11-01 00:00:00

abstract：:The aim of this study was to investigate the interrelationship between the mitochondrial phospholipid cardiolipin (CL), mitochondrial respiration and morphology in dependence on hypoxia/reoxygenation and Ca(2+). Therefore, we subjected rat liver mitochondria to hypoxia/reoxygenation at different extramitochondrial Ca(...

journal_title：Molecular and cellular biochemistry

authors： Martens JC,Keilhoff G,Gardemann A,Schild L

更新日期：2014-09-01 00:00:00

abstract：:Under normal and ischemic conditions backdiffusion of radiolabeled non-esterified fatty acids (NEFA) has been demonstrated. In the fasted normal canine heart the extraction fraction (EF) during interventions with glucose or lactate loading, vasodilation, and metabolic level augmentation was determined, and compared wi...

journal_title：Molecular and cellular biochemistry

authors： Duwel CM,Visser FC,van Eenige MJ,Roos JP

更新日期：1989-06-27 00:00:00

abstract：:Guanylyl cyclases in eukaryotic unicells were biochemically investigated in the ciliates Paramecium and Tetrahymena, in the malaria parasite Plasmodium and in the ameboid Dictyostelium. In ciliates guanylyl cyclase activity is calcium-regulated suggesting a structural kinship to similarly regulated membrane-bound guan...

journal_title：Molecular and cellular biochemistry

authors： Linder JU,Schultz JE

更新日期：2002-01-01 00:00:00

abstract：:Plasma membrane fractions from normal, regenerating liver and the AS-30D ascites hepatocarcinoma exhibited a high degree of enrichment when a set of plasma membrane enzyme markers were studied in comparison to the ones associated to the mitochondrial and cytosolic compartments. While the (Ca2+, Mg2+)-ATPase observed f...

journal_title：Molecular and cellular biochemistry

authors： Mas-Oliva J,Pérez-Montfort R,Cárdenas-García M,Rivas-Duro M

更新日期：1991-01-16 00:00:00

abstract：:Physical training induces cardiovascular autonomic nervous system regulation adaptations, which could result from beta adrenergic receptor (AR) modifications. Among them, beta(3 )AR alterations have been recently reported but their functional effect remained to discuss. To explain the beta(3) AR gene expression in rel...

journal_title：Molecular and cellular biochemistry

authors： Barbier J,Rannou-Bekono F,Marchais J,Tanguy S,Carré F

更新日期：2007-06-01 00:00:00

abstract：:The aim of this study was to determine the effect of magnesium deficiency on small intestinal morphology and function. Rats were assigned to 4 groups and placed on magnesium sufficient or deficient diet for 1 or 3 weeks. Infiltration of neutrophils and mucosal injury were assessed in stained sections of small intestin...

journal_title：Molecular and cellular biochemistry

authors： Scanlan BJ,Tuft B,Elfrey JE,Smith A,Zhao A,Morimoto M,Chmielinska JJ,Tejero-Taldo MI,Mak IuT,Weglicki WB,Shea-Donohue T

更新日期：2007-12-01 00:00:00

abstract：:The contribution of anti-inflammatory property of celecoxib in the improvement of metabolic disorders in cancer is unknown. The purpose of this study was to compare the effects of celecoxib and ibuprofen, non-steroidal anti-inflammatory drugs (NSAIDs), on several metabolic changes observed in Walker-256 tumor-bearing ...

journal_title：Molecular and cellular biochemistry

authors： de Souza CO,Kurauti MA,de Fatima Silva F,de Morais H,Borba-Murad GR,de Andrade FG,de Souza HM

更新日期：2015-01-01 00:00:00

abstract：:Fatty acid uptake and metabolism are often dysregulated in cancer cells. Fatty acid activation is a critical step that allows these biomolecules to enter cellular metabolic pathways such as mitochondrial β-oxidation for ATP generation or the lipogenic routes that generate bioactive lipids such as the inositol phosphol...

journal_title：Molecular and cellular biochemistry

authors： Radif Y,Ndiaye H,Kalantzi V,Jacobs R,Hall A,Minogue S,Waugh MG

更新日期：2018-11-01 00:00:00

abstract：:The homeodomain-containing Msx3 gene, the newest member of the Msx family, encodes two mRNAs, with an unknown relationship to each other. To elucidate how Msx3 gene generates the two transcripts, we cloned their corresponding cDNAs from an E10.5 mouse embryo cDNA library. The alignment of sequences of the two Msx3-spe...

journal_title：Molecular and cellular biochemistry

authors： Matsui H,Takahashi T,Raghow R

更新日期：2004-12-01 00:00:00

abstract：:p62/sequestosome-1 is a multifunctional adapter protein implicated in selective autophagy, cell signaling pathways, and tumorigenesis, and plays an important role at the crossroad between autophagy and cancer. But, the connection between autophagy and cancer is complex and in some cases contradictory. Human colorectal...

journal_title：Molecular and cellular biochemistry

authors： Ren F,Shu G,Liu G,Liu D,Zhou J,Yuan L,Zhou J

更新日期：2014-01-01 00:00:00

abstract：:Endothelial dysfunction is one of the most important pathological events during the development of several diabetic complications including stroke. The aim of this work was to investigate the role of actin depolymerizing factor (ADF) in advanced glycation endproducts (AGEs)-induced impairment in mouse brain microvascu...

journal_title：Molecular and cellular biochemistry

authors： Liu X,Zhang R,Di H,Zhao D,Wang J

更新日期：2017-09-01 00:00:00

abstract：:In rat cardiac sarcolemmal membranes a phosphoinositide-specific phospholipase C (PLC) was found to be present. The enzyme hydrolysed exogenous [3H-]phosphatidylinositol 4,5-biphosphate ([3H-]PtdIns(4,5)P2) in an optimized assay mixture containing 15 micrograms SL protein, 100 mM NaCl, 1 mM free Ca2+, 14 mM Na-cholate...

journal_title：Molecular and cellular biochemistry

authors： Meij JT,Panagia V

更新日期：1992-10-21 00:00:00