Electron g-factor in nanostructures: continuum media and atomistic approach.

abstract：:The DNA methyltransferase DNMT3A R882H mutation is observed in 25% of all AML patients. DNMT3A is active as tetramer and the R882H mutation is located in one of the subunit/subunit interfaces. Previous work has reported that formation of mixed wildtype/R882H complexes leads to a strong loss of catalytic activity obser...

journal_title：Scientific reports

authors： Emperle M,Dukatz M,Kunert S,Holzer K,Rajavelu A,Jurkowska RZ,Jeltsch A

更新日期：2018-09-05 00:00:00

abstract：:In kidney disease, higher circulating levels of the mineral-regulating hormone fibroblast growth factor (FGF)-23 are predictive of disease progression but direct pathogenic effects on the kidney are unknown. We sought evidence of local renal synthesis in response to unilateral ureteric obstruction in the mouse, and pr...

journal_title：Scientific reports

authors： Smith ER,Tan SJ,Holt SG,Hewitson TD

更新日期：2017-06-13 00:00:00

abstract：:H5N1 highly pathogenic avian influenza virus (HPAIV) poses a huge threat to public health and the global economy. These viruses cause systemic infection in poultry and accidental human infection leads to severe pneumonia, associated with high mortality rates. The hemagglutinin (HA) of H5N1 HPAIV possesses multiple bas...

journal_title：Scientific reports

authors： Kajiwara N,Nomura N,Ukaji M,Yamamoto N,Kohara M,Yasui F,Sakoda Y,Kida H,Shibasaki F

更新日期：2020-10-22 00:00:00

abstract：:Willow (Salix spp.) seeds are able to tolerate desiccation, but differ from typical orthodox seeds in that they lose viability in a few days at room temperature, and in that the chloroplasts in embryo tissues do not dedifferentiate during maturation drying, thus retaining chlorophyll and maintaining intact their thyla...

journal_title：Scientific reports

authors： López-Fernández MP,Moyano L,Correa MD,Vasile F,Burrieza HP,Maldonado S

更新日期：2018-11-21 00:00:00

abstract：:T helper 17 (Th17) cells not only play critical roles in protecting against bacterial and fungal infections but are also involved in the pathogenesis of autoimmune diseases. The retinoic acid-related orphan receptor (RORγt) is a key transcription factor involved in Th17 cell differentiation through direct transcriptio...

journal_title：Scientific reports

authors： Wu Q,Nie J,Gao Y,Xu P,Sun Q,Yang J,Han L,Chen Z,Wang X,Lv L,Tsun A,Shen J,Li B

更新日期：2015-11-09 00:00:00

abstract：:Sixty-six million years ago, an asteroid approximately 9 km in diameter hit the hydrocarbon- and sulfur-rich sedimentary rocks in what is now Mexico. Recent studies have shown that this impact at the Yucatan Peninsula heated the hydrocarbon and sulfur in these rocks, forming stratospheric soot and sulfate aerosols and...

journal_title：Scientific reports

authors： Kaiho K,Oshima N

更新日期：2017-11-09 00:00:00

abstract：:Pediatric obstructive sleep-disordered breathing is associated with growth retardation, but also with obesity that has a tendency to persist following treatment. We investigated the effect of upper airways obstruction (AO) and of obstruction removal (OR) in juvenile rats on gut-derived ghrelin and related hypothalamic...

journal_title：Scientific reports

authors： Assadi MH,Shknevsky E,Segev Y,Tarasiuk A

更新日期：2017-06-02 00:00:00

abstract：:Bacterial β-glucuronidase (GUS) enzymes cause drug toxicity by reversing Phase II glucuronidation in the gastrointestinal tract. While many human gut microbial GUS enzymes have been examined with model glucuronide substrates like p-nitrophenol-β-D-glucuronide (pNPG), the GUS orthologs that are most efficient at proces...

journal_title：Scientific reports

authors： Biernat KA,Pellock SJ,Bhatt AP,Bivins MM,Walton WG,Tran BNT,Wei L,Snider MC,Cesmat AP,Tripathy A,Erie DA,Redinbo MR

更新日期：2019-01-29 00:00:00

abstract：:Histone lysine acetyltransferase (KAT)-catalyzed acetylation of lysine residues in histone tails plays a key role in regulating gene expression in eukaryotes. Here, we examined the role of lysine side chain length in the catalytic activity of human KATs by incorporating shorter and longer lysine analogs into synthetic...

journal_title：Scientific reports

authors： Proietti G,Wang Y,Rainone G,Mecinović J

更新日期：2020-08-03 00:00:00

abstract：:Aerosols impact clear-sky surface irradiance () through the effects of scattering and absorption. Linear or nonlinear relationships between aerosol optical depth (τa) and have been established to describe the aerosol direct radiative effect on (ADRE). However, considerable uncertainties remain associated with ADRE due...

journal_title：Scientific reports

authors： Xia X

更新日期：2015-09-23 00:00:00

abstract：:The marine bacterial strain Desulfovibrio ferrophilus IS5, known for its lithotrophic growth ability to use metallic iron as a sole electron donor and for causing corrosion of steel, was used in the current study. Four commonly used biocides in the oil and gas industry, namely tetrakis(hydroxymethyl) phosphonium sulfa...

journal_title：Scientific reports

authors： Sharma M,Liu H,Chen S,Cheng F,Voordouw G,Gieg L

更新日期：2018-11-09 00:00:00

abstract：:The protective effect of estrogens against chronic glomerular diseases is admitted but remains debated during acute kidney injury (AKI). Using a model of resuscitated hemorrhagic shock in C57/Bl6 female mice, this study evaluated at 1 and 21 days the renal effect of (1) endogenous estrogen, using ovariectomized mice w...

journal_title：Scientific reports

authors： Buléon M,Cuny M,Grellier J,Charles PY,Belliere J,Casemayou A,Arnal JF,Schanstra JP,Tack I

更新日期：2020-10-14 00:00:00

abstract：:Hypoadiponectinemia and adiponectin resistance are implicated in the aetiology of obesity-related cardiometabolic disorders, hence represent a potential therapeutic axis. Here we characterised the effects of in vivo electrotransfer-mediated overexpression of the adiponectin receptors, AdipoR1 or AdipoR2, into tibialis...

journal_title：Scientific reports

authors： Keshvari S,Henstridge DC,Ng C,Febbraio MA,Whitehead JP

更新日期：2017-02-01 00:00:00

abstract：:Fungus-growing termites engage in an obligate mutualistic relationship with Termitomyces fungi, which they maintain in monocultures on specialised fungus comb structures, without apparent problems with infectious diseases. While other fungi have been reported in the symbiosis, detailed comb fungal community analyses h...

journal_title：Scientific reports

authors： Otani S,Challinor VL,Kreuzenbeck NB,Kildgaard S,Krath Christensen S,Larsen LLM,Aanen DK,Rasmussen SA,Beemelmanns C,Poulsen M

更新日期：2019-06-19 00:00:00

abstract：:Immune responses against gene therapy products limit its therapeutic efficacy and present a safety risk. Identification of agents that blunt immune reactions may aid in developing novel immunomodulatory therapies. Fingolimod (FTY720) is an FDA approved immunomodulatory drug for treating multiple sclerosis that inhibit...

journal_title：Scientific reports

authors： Baer A,Colon-Moran W,Bhattarai N

更新日期：2018-07-19 00:00:00

abstract：:Arachidonic acid (AA) is metabolized to diverse bioactive lipid mediators. Whereas the 5-lipoxygenase-activating protein (FLAP) facilitates AA conversion by 5-lipoxygenase (5-LOX) to pro-inflammatory leukotrienes (LTs), the soluble epoxide hydrolase (sEH) degrades anti-inflammatory epoxyeicosatrienoic acids (EETs). Ac...

journal_title：Scientific reports

authors： Garscha U,Romp E,Pace S,Rossi A,Temml V,Schuster D,König S,Gerstmeier J,Liening S,Werner M,Atze H,Wittmann S,Weinigel C,Rummler S,Scriba GK,Sautebin L,Werz O

更新日期：2017-08-24 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) is characterized by a fibrotic and inflammatory microenvironment that is formed primarily by activated, myofibroblast-like, stellate cells. Although the stellate cells are thought to contribute to tumorigenesis, metastasis and drug resistance of PDAC, the signaling events involv...

journal_title：Scientific reports

authors： Morvaridi S,Dhall D,Greene MI,Pandol SJ,Wang Q

更新日期：2015-11-16 00:00:00

abstract：:Fluorine-19 (19F) magnetic resonance imaging (MRI) of injected perfluorocarbons (PFCs) can be used for the quantification and monitoring of inflammation in diseases such as atherosclerosis. To advance the translation of this technique to the clinical setting, we aimed to 1) demonstrate the feasibility of quantitative ...

journal_title：Scientific reports

authors： Darçot E,Colotti R,Pellegrin M,Wilson A,Siegert S,Bouzourene K,Yerly J,Mazzolai L,Stuber M,van Heeswijk RB

更新日期：2019-11-25 00:00:00

abstract：:A novel linear polarization converter operating in C- and X-bands with high polarization conversion ratio is described and demonstrated based on frequency selective surface. The building element is a planar-dipole pair, which is orthogonally printed on a double-layer substrate and vertically connected by a pair of thr...

journal_title：Scientific reports

authors： Wang SY,Liu W,Geyi W

更新日期：2018-02-28 00:00:00

abstract：:Ammonia can be utilised as an alternative nitrogen source to glutamine to support cell proliferation. However, the underlying molecular mechanisms and whether all cells have this ability is not fully understood. We find that eleven cancer and non-cancerous cell lines have opposite abilities to tolerate and utilise amm...

journal_title：Scientific reports

authors： Lie S,Wang T,Forbes B,Proud CG,Petersen J

更新日期：2019-02-06 00:00:00

abstract：:Neuronal activity-dependent synaptic plasticity, a basis for learning and memory, is tightly correlated with the pattern of increase in intracellular Ca(2+) concentration ([Ca(2+)](i)). Here, using combined application of electrophysiological experiments and systems biological simulation, we show that such a correlati...

journal_title：Scientific reports

authors： Kawaguchi SY,Nagasaki N,Hirano T

更新日期：2011-01-01 00:00:00

abstract：:Tolmetin is a non-steroidal anti-inflammatory drug being used to decrease the level of hormones which are the reasons for pain, swelling, tiredness, and stiffness for osteoarthritis and rheumatoid arthritis cases. We evaluated its solubility in supercritical carbon dioxide (SC-CO2) with the aim of drug nanonization, c...

journal_title：Scientific reports

authors： Pishnamazi M,Zabihi S,Sarafzadeh P,Borousan F,Marjani A,Pelalak R,Shirazian S

更新日期：2020-11-11 00:00:00

abstract：:Autografts tend to be unreliable in older patients. Some of these age-related skeletal changes appear to be attributable to a decline in endogenous WNT signaling. We used a functional in vivo transplantation assay to demonstrate that the bone-forming capacity of an autograft can be traced back to a Wnt-responsive cell...

journal_title：Scientific reports

authors： Chen T,Li J,Córdova LA,Liu B,Mouraret S,Sun Q,Salmon B,Helms J

更新日期：2018-01-08 00:00:00

abstract：:Behavioral alterations emerging after central or peripheral vision loss suggest that cerebral reorganization occurs for both the afferented and deafferented early visual cortex (EVC). We explored the functional reorganization of the central and peripheral EVC following visual field defects specifically affecting centr...

journal_title：Scientific reports

authors： Sabbah N,Sanda N,Authié CN,Mohand-Saïd S,Sahel JA,Habas C,Amedi A,Safran AB

更新日期：2017-02-24 00:00:00

abstract：:Emerging infectious pathogens that threaten blood transfusions are known to be present in blood samples from healthy/qualified donors. The objective of this study was to investigate the microbiome of blood from healthy donors from the Luzhou area in southwestern China. Potential pathogens and cytomegalovirus (CMV) inf...

journal_title：Scientific reports

authors： Xu M,Gao J,Li S,Zeng M,Wu J,Luo M

更新日期：2020-09-25 00:00:00

abstract：:Most of Quantum Secret Sharing(QSS) are (n, n) threshold 2-level schemes, in which the 2-level secret cannot be reconstructed until all n shares are collected. In this paper, we propose a (t, n) threshold d-level QSS scheme, in which the d-level secret can be reconstructed only if at least t shares are collected. Comp...

journal_title：Scientific reports

authors： Song XL,Liu YB,Deng HY,Xiao YG

更新日期：2017-07-25 00:00:00

abstract：:Osteoporosis is a disease characterized by low bone mass and progressive destruction of bone microstructure, resulting in increased the risk of fracture. Previous studies have demonstrated the effect of naringin (NG) or treadmill exercise (EX) on osteoporosis, however, reports about effects of NG plus EX on osteoporos...

journal_title：Scientific reports

authors： Sun X,Li F,Ma X,Ma J,Zhao B,Zhang Y,Li Y,Lv J,Meng X

更新日期：2015-08-11 00:00:00

abstract：:The availability of genotyping assays has allowed the detailed evaluation of cattle genetic diversity worldwide. However, these comprehensive studies did not include some local European populations, including autochthonous Italian cattle. In this study, we assembled a large-scale, genome-wide dataset of single nucleot...

journal_title：Scientific reports

authors： Mastrangelo S,Tolone M,Ben Jemaa S,Sottile G,Di Gerlando R,Cortés O,Senczuk G,Portolano B,Pilla F,Ciani E

更新日期：2020-09-03 00:00:00

abstract：:The aim of the study was to compare background characteristics, microbiology and outcome of patients with right-sided and left-sided intravenous drug use (IDU) associated infective endocarditis (IE). A nationwide retrospective study using the Swedish Registry on Infective Endocarditis between 2008 and 2019 was conduct...

journal_title：Scientific reports

authors： Clarelin A,Rasmussen M,Olaison L,Ragnarsson S

更新日期：2021-01-13 00:00:00

abstract：:The goal of this study was to evaluate if isolated sarcomeres and half-sarcomeres produce a long-lasting increase in force after a stretch is imposed during activation. Single and half-sarcomeres were isolated from myofibrils using micro-needles, which were also used for force measurements. After full force developmen...

journal_title：Scientific reports

authors： Minozzo FC,Baroni BM,Correa JA,Vaz MA,Rassier DE

更新日期：2013-01-01 00:00:00