Interactions with conspecific outsiders as drivers of cognitive evolution.

abstract：:Genomic and phenotypic analyses indicate extensive intra- as well as intertumoral heterogeneity in primary human malignant cell populations despite their clonal origin. Cellular DNA barcoding offers a powerful and unbiased alternative to track the number and size of multiple subclones within a single human tumour xeno...

journal_title：Nature communications

authors： Nguyen LV,Cox CL,Eirew P,Knapp DJ,Pellacani D,Kannan N,Carles A,Moksa M,Balani S,Shah S,Hirst M,Aparicio S,Eaves CJ

更新日期：2014-12-23 00:00:00

abstract：:The energy band alignment in solar cell devices is critically important because it largely governs elementary photovoltaic processes, such as the generation, separation, transport, recombination and collection of charge carriers. Despite the expenditure of considerable effort, the measurement of energy band depth prof...

journal_title：Nature communications

authors： Chen Q,Mao L,Li Y,Kong T,Wu N,Ma C,Bai S,Jin Y,Wu D,Lu W,Wang B,Chen L

更新日期：2015-07-13 00:00:00

abstract：:Bulk photovoltaic effect (BPVE), featuring polarization-dependent uniform photoresponse at zero external bias, holds potential for exceeding the Shockley-Queisser limit in the efficiency of existing opto-electronic devices. However, the implementation of BPVE has been limited to the naturally existing materials with b...

journal_title：Nature communications

authors： Wei J,Li Y,Wang L,Liao W,Dong B,Xu C,Zhu C,Ang KW,Qiu CW,Lee C

更新日期：2020-12-17 00:00:00

abstract：:In most applications of nanoporous materials the pore structure is as important as the chemical composition as a determinant of performance. For example, one can alter performance in applications like carbon capture or methane storage by orders of magnitude by only modifying the pore structure. For these applications ...

journal_title：Nature communications

authors： Lee Y,Barthel SD,Dłotko P,Moosavi SM,Hess K,Smit B

更新日期：2017-05-23 00:00:00

abstract：:The metazoan TREX complex is recruited to mRNA during nuclear RNA processing and functions in exporting mRNA to the cytoplasm. Nxf1 is an mRNA export receptor, which binds processed mRNA and transports it through the nuclear pore complex. At present, the relationship between TREX and Nxf1 is not understood. Here we sh...

journal_title：Nature communications

authors： Viphakone N,Hautbergue GM,Walsh M,Chang CT,Holland A,Folco EG,Reed R,Wilson SA

更新日期：2012-01-01 00:00:00

abstract：:Crosstalk between inflammatory signalling pathways and receptor tyrosine kinases has been revealed as an indicator of cancer malignant progression. In the present study, we focus on EphA2 receptor tyrosine kinase, which is overexpressed in many human cancers. It has been reported that ligand-independent phosphorylatio...

journal_title：Nature communications

authors： Zhou Y,Yamada N,Tanaka T,Hori T,Yokoyama S,Hayakawa Y,Yano S,Fukuoka J,Koizumi K,Saiki I,Sakurai H

更新日期：2015-07-09 00:00:00

abstract：:Plasmacytoid dendritic cells (pDC) are type I interferon-producing cells with critical functions in a number of human illnesses; however, their molecular regulation is incompletely understood. Here we show the role of Src family kinases (SFK) in mouse and human pDCs. pDCs express Fyn and Lyn and their activating resid...

journal_title：Nature communications

authors： Dallari S,Macal M,Loureiro ME,Jo Y,Swanson L,Hesser C,Ghosh P,Zuniga EI

更新日期：2017-04-03 00:00:00

abstract：:The European steppes and their biota have been hypothesized to be either young remnants of the Pleistocene steppe belt or, alternatively, to represent relicts of long-term persisting populations; both scenarios directly bear on nature conservation priorities. Here, we evaluate the conservation value of threatened disj...

journal_title：Nature communications

authors： Kirschner P,Záveská E,Gamisch A,Hilpold A,Trucchi E,Paun O,Sanmartín I,Schlick-Steiner BC,Frajman B,Arthofer W,STEPPE Consortium.,Steiner FM,Schönswetter P

更新日期：2020-04-23 00:00:00

abstract：:The resting-state human brain networks underlie fundamental cognitive functions and consist of complex interactions among brain regions. However, the level of complexity of the resting-state networks has not been quantified, which has prevented comprehensive descriptions of the brain activity as an integrative system....

journal_title：Nature communications

authors： Watanabe T,Hirose S,Wada H,Imai Y,Machida T,Shirouzu I,Konishi S,Miyashita Y,Masuda N

更新日期：2013-01-01 00:00:00

abstract：:Distal appendages (DAPs) are nanoscale, pinwheel-like structures protruding from the distal end of the centriole that mediate membrane docking during ciliogenesis, marking the cilia base around the ciliary gate. Here we determine a super-resolved multiplex of 16 centriole-distal-end components. Surprisingly, rather th...

journal_title：Nature communications

authors： Yang TT,Chong WM,Wang WJ,Mazo G,Tanos B,Chen Z,Tran TMN,Chen YD,Weng RR,Huang CE,Jane WN,Tsou MB,Liao JC

更新日期：2018-05-22 00:00:00

abstract：:Thin-film transistor (TFT)-driven full-color organic light-emitting diodes (OLEDs) with vertically stacked structures are developed herein using photolithography processes, which allow for high-resolution displays of over 2,000 pixels per inch. Vertical stacking of OLEDs by the photolithography process is technically ...

journal_title：Nature communications

authors： Choi S,Kang CM,Byun CW,Cho H,Kwon BH,Han JH,Yang JH,Shin JW,Hwang CS,Cho NS,Lee KM,Kim HO,Kim E,Yoo S,Lee H

更新日期：2020-06-01 00:00:00

abstract：:Consolidation stabilizes memory traces after initial encoding. Rodent studies suggest that memory consolidation depends on replay of stimulus-specific activity patterns during fast hippocampal "ripple" oscillations. Here, we measured replay in intracranial electroencephalography recordings in human epilepsy patients, ...

journal_title：Nature communications

authors： Zhang H,Fell J,Axmacher N

更新日期：2018-10-05 00:00:00

abstract：:The expression and stabilization of recombinant proteins is fundamental to basic and applied biology. Here we have engineered a thermostable protein nanoparticle (tES) to improve both expression and stabilization of recombinant proteins using this technology. tES provides steric accommodation and charge complementatio...

journal_title：Nature communications

authors： Deshpande S,Masurkar ND,Girish VM,Desai M,Chakraborty G,Chan JM,Drum CL

更新日期：2017-11-13 00:00:00

abstract：:The actin-like protein MreB has been proposed to coordinate the synthesis of the cell wall to determine cell shape in bacteria. MreB is preferentially localized to areas of the cell with specific curved geometries, avoiding the cell poles. It remains unclear whether MreB's curvature preference is regulated by addition...

journal_title：Nature communications

authors： Bratton BP,Shaevitz JW,Gitai Z,Morgenstein RM

更新日期：2018-07-18 00:00:00

abstract：:Pentatricopeptide repeat (PPR) proteins control diverse aspects of RNA metabolism in eukaryotic cells. Although recent computational and structural studies have provided insights into RNA recognition by PPR proteins, their highly insoluble nature and inconsistencies between predicted and observed modes of RNA binding ...

journal_title：Nature communications

authors： Coquille S,Filipovska A,Chia T,Rajappa L,Lingford JP,Razif MF,Thore S,Rackham O

更新日期：2014-12-17 00:00:00

abstract：:A key feature of meiosis is the step-wise removal of cohesin, the protein complex holding sister chromatids together, first from arms in meiosis I and then from the centromere region in meiosis II. Centromeric cohesin is protected by Sgo2 from Separase-mediated cleavage, in order to maintain sister chromatids together...

journal_title：Nature communications

authors： El Yakoubi W,Buffin E,Cladière D,Gryaznova Y,Berenguer I,Touati SA,Gómez R,Suja JA,van Deursen JM,Wassmann K

更新日期：2017-09-25 00:00:00

abstract：:Soil surface temperature, an important driver of terrestrial biogeochemical processes, depends strongly on soil albedo, which can be significantly modified by factors such as plant cover. In sparsely vegetated lands, the soil surface can be colonized by photosynthetic microbes that build biocrust communities. Here we ...

journal_title：Nature communications

authors： Couradeau E,Karaoz U,Lim HC,Nunes da Rocha U,Northen T,Brodie E,Garcia-Pichel F

更新日期：2016-01-20 00:00:00

abstract：:Characterizing complex viral transcriptomes by conventional RNA sequencing approaches is complicated by high gene density, overlapping reading frames, and complex splicing patterns. Direct RNA sequencing (direct RNA-seq) using nanopore arrays offers an exciting alternative whereby individual polyadenylated RNAs are se...

journal_title：Nature communications

authors： Depledge DP,Srinivas KP,Sadaoka T,Bready D,Mori Y,Placantonakis DG,Mohr I,Wilson AC

更新日期：2019-02-14 00:00:00

abstract：:Activation of innate immunity by membrane-localized receptors is conserved across eukaryotes. Plant genomes contain hundreds of such receptor-like genes and those encoding proteins with an extracellular leucine-rich repeat (LRR) domain represent the largest family. Here, we develop a high-throughput approach to study ...

journal_title：Nature communications

authors： Wang Y,Xu Y,Sun Y,Wang H,Qi J,Wan B,Ye W,Lin Y,Shao Y,Dong S,Tyler BM,Wang Y

更新日期：2018-02-09 00:00:00

abstract：:Janus, patchy, stripe-like, or random arrangements of molecules within the ligand shell of nanoparticles affect many properties. Among all existing ligand shell morphology characterization methods, the one based on mass spectroscopy is arguably the simplest. Its greatest limitation is that the results are qualitative....

journal_title：Nature communications

authors： Luo Z,Zhao Y,Darwish T,Wang Y,Hou J,Stellacci F

更新日期：2018-10-26 00:00:00

abstract：:Wild boar (Sus scrofa) drastically colonized mainland Eurasia and North Africa, most likely from East Asia during the Plio-Pleistocene (2-1Mya). In recent studies, based on genome-wide information, it was hypothesized that wild boar did not replace the species it encountered, but instead exchanged genetic materials wi...

journal_title：Nature communications

authors： Liu L,Bosse M,Megens HJ,Frantz LAF,Lee YL,Irving-Pease EK,Narayan G,Groenen MAM,Madsen O

更新日期：2019-04-30 00:00:00

abstract：:Cascade reactions initiated by radical addition to alkynes are synthetically very attractive because they enable access to highly complex molecular skeletons in only few synthetic steps under usually mild conditions. Here we report a general radical cascade reaction of alkynes, N-fluoroarylsulfonimides and alcohols, e...

journal_title：Nature communications

authors： Zheng G,Li Y,Han J,Xiong T,Zhang Q

更新日期：2015-04-22 00:00:00

abstract：:Inflammation is recognized as one of the drivers of cancer. Yet, the individual immune components that possess pro- and anti-tumorigenic functions in individual cancers remain largely unknown. NKG2D is a potent activating immunoreceptor that has emerged as an important player in inflammatory disorders besides its well...

journal_title：Nature communications

authors： Sheppard S,Guedes J,Mroz A,Zavitsanou AM,Kudo H,Rothery SM,Angelopoulos P,Goldin R,Guerra N

更新日期：2017-01-27 00:00:00

abstract：:Ruddlesden-Popper halide perovskites are 2D solution-processed quantum wells with a general formula A2A'n-1M n X3n+1, where optoelectronic properties can be tuned by varying the perovskite layer thickness (n-value), and have recently emerged as efficient semiconductors with technologically relevant stability. However,...

journal_title：Nature communications

authors： Blancon JC,Stier AV,Tsai H,Nie W,Stoumpos CC,Traoré B,Pedesseau L,Kepenekian M,Katsutani F,Noe GT,Kono J,Tretiak S,Crooker SA,Katan C,Kanatzidis MG,Crochet JJ,Even J,Mohite AD

更新日期：2018-06-08 00:00:00

abstract：:To overcome the fundamental challenge of the weak natural response of antiferromagnetic materials under a magnetic field, voltage manipulation of antiferromagnetic interaction is developed to realize ultrafast, high-density, and power efficient antiferromagnetic spintronics. Here, we report a low voltage modulation of...

journal_title：Nature communications

authors： Yang Q,Wang L,Zhou Z,Wang L,Zhang Y,Zhao S,Dong G,Cheng Y,Min T,Hu Z,Chen W,Xia K,Liu M

更新日期：2018-03-07 00:00:00

abstract：:Whole-genome sequencing using sequencing technologies such as Illumina enables the accurate detection of small-scale variants but provides limited information about haplotypes and variants in repetitive regions of the human genome. Single-molecule sequencing (SMS) technologies such as Pacific Biosciences and Oxford Na...

journal_title：Nature communications

authors： Edge P,Bansal V

更新日期：2019-10-11 00:00:00

abstract：:Epithelial barrier function is maintained by coordination of cell proliferation and cell loss, whereas barrier dysfunction can lead to disease and organismal death. JNK signalling is a conserved stress signalling pathway activated by bacterial infection and tissue damage, often leading to apoptotic cell death and comp...

journal_title：Nature communications

authors： Zhou J,Edgar BA,Boutros M

更新日期：2017-03-08 00:00:00

abstract：:Peptide-major histocompatibility complex class II (pMHCII)-based nanomedicines displaying tissue-specific autoantigenic epitopes can blunt specific autoimmune conditions by re-programming cognate antigen-experienced CD4+ T-cells into disease-suppressing T-regulatory type 1 (TR1) cells. Here, we show that single pMHCII...

journal_title：Nature communications

authors： Umeshappa CS,Singha S,Blanco J,Shao K,Nanjundappa RH,Yamanouchi J,Parés A,Serra P,Yang Y,Santamaria P

更新日期：2019-05-14 00:00:00

abstract：:Viruses cause 10-15% of all human cancers. Massively parallel sequencing has recently proved effective for uncovering novel viruses and virus-tumour associations, but this approach has not yet been applied to comprehensive patient cohorts. Here we screen a diverse landscape of human cancer, encompassing 4,433 tumours ...

journal_title：Nature communications

authors： Tang KW,Alaei-Mahabadi B,Samuelsson T,Lindh M,Larsson E

更新日期：2013-01-01 00:00:00

abstract：:Sphingosine-1-phosphate (S1P) participates in inflammation; however, its role in leukocyte rolling is still unclear. Here we use intravital microscopy in inflamed mouse cremaster muscle venules and human endothelial cells to show that S1P contributes to P-selectin-dependent leukocyte rolling through endothelial S1P re...

journal_title：Nature communications

authors： Nussbaum C,Bannenberg S,Keul P,Gräler MH,Gonçalves-de-Albuquerque CF,Korhonen H,von Wnuck Lipinski K,Heusch G,de Castro Faria Neto HC,Rohwedder I,Göthert JR,Prasad VP,Haufe G,Lange-Sperandio B,Offermanns S,Sperandio M,Lev

更新日期：2015-04-02 00:00:00