Emerging MDR-Pseudomonas aeruginosa in fish commonly harbor oprL and toxA virulence genes and blaTEM, blaCTX-M, and tetA antibiotic-resistance genes.

abstract：:Transition metal dichalcogenides (TMDCs) are promising materials for sensing applications, due to their exceptional high performance in nano-electronics. Inherentely, the chemical and thermal responses of TMDCs are highly stable, hence, they pave way for real time sensor applications. This article proposes inceptively...

journal_title：Scientific reports

authors： Awais M,Khan MU,Hassan A,Bae J,Chattha TE

更新日期：2020-03-26 00:00:00

abstract：:Identification of key regulators and regulatory pathways is an important step in the discovery of genes involved in cancer. Here, we propose a method to identify key regulators in prostate cancer (PCa) from a network constructed from gene expression datasets of PCa patients. Overexpressed genes were identified using B...

journal_title：Scientific reports

authors： Mangangcha IR,Malik MZ,Küçük Ö,Ali S,Singh RKB

更新日期：2019-11-11 00:00:00

abstract：:This study aimed to investigate the dosimetric characteristics of an isocentrically shielded RapidArc (IS-RA) technique for treatment of locally recurrent nasopharyngeal cancer (lrNPC). In IS-RA, the isocenter was placed at the center of the pre-irradiated brainstem (BS)/spinal cord (SC) and the jaws were set to shiel...

journal_title：Scientific reports

authors： Lu JY,Huang BT,Xing L,Chang DT,Peng X,Xie LX,Lin ZX,Li M

更新日期：2016-05-13 00:00:00

abstract：:Male moths use species-specific sex pheromones to identify and orientate toward conspecific females. Odorant receptors (ORs) for sex pheromone substances have been identified as sex pheromone receptors in various moth species. However, direct in vivo evidence linking the functional role of these ORs with behavioural r...

journal_title：Scientific reports

authors： Sakurai T,Mitsuno H,Mikami A,Uchino K,Tabuchi M,Zhang F,Sezutsu H,Kanzaki R

更新日期：2015-06-05 00:00:00

abstract：:Peatland ecosystem services include drinking water provision, flood mitigation, habitat provision and carbon sequestration. Dissolved organic carbon (DOC) removal is a key treatment process for the supply of potable water downstream from peat-dominated catchments. A transition from peat-forming Sphagnum moss to vascul...

journal_title：Scientific reports

authors： Ritson JP,Bell M,Brazier RE,Grand-Clement E,Graham NJ,Freeman C,Smith D,Templeton MR,Clark JM

更新日期：2016-11-18 00:00:00

abstract：:Detecting neuroplastic changes during locomotor neurorehabilitation is crucial for independent primal motor behaviours. However, long-term locomotor training-related neuroplasticity remains unexplored. We compared the effects of end-effector robot-assisted gait training (E-RAGT) and bodyweight-supported treadmill trai...

journal_title：Scientific reports

authors： Kim H,Park G,Shin JH,You JH

更新日期：2020-07-27 00:00:00

abstract：:Sacha inchi (Plukenetia volubilis L.) is a shrub native to Amazon rainforests that's of commercial interest as its seeds contain 35-60% edible oil (dry weight). This oil is one of the healthiest vegetable oils due to its high polyunsaturated fatty acid content and favourable ratio of omega-6 to omega-3 fatty acids. De...

journal_title：Scientific reports

authors： Liu G,Wu Z,Peng Y,Shang X,Xie Y,Arnold RJ

更新日期：2020-11-24 00:00:00

abstract：:We investigated the ocular surface (OS) system modifications after completely successful glaucoma surgery in thirty-eight patients undergoing trabeculectomy (surgical group), using laser scanning confocal microscopy (LSCM) and impression cytology (IC). Twenty-six medically controlled glaucomatous patients served as co...

journal_title：Scientific reports

authors： Agnifili L,Brescia L,Oddone F,Sacchi M,D'Ugo E,Di Marzio G,Perna F,Costagliola C,Mastropasqua R

更新日期：2019-08-05 00:00:00

abstract：:Cell motility requires the precise coordination of cell polarization, lamellipodia formation, adhesion, and force generation. LKB1 is a multi-functional serine/threonine kinase that associates with actin at the cellular leading edge of motile cells and suppresses FAK. We sought to understand how LKB1 coordinates these...

journal_title：Scientific reports

authors： Wilkinson S,Hou Y,Zoine JT,Saltz J,Zhang C,Chen Z,Cooper LA,Marcus AI

更新日期：2017-01-19 00:00:00

abstract：:Tunable metasurfaces have emerged as an efficient approach to manipulate the wave propagation. Different from previous work concentrating on electrically tunable mechanisms, here we demonstrate a magnetically tunable metasurface composed of ferrite rods and metallic foils. By tuning the thickness of ferrite rods, meta...

journal_title：Scientific reports

authors： Yang H,Yu T,Wang Q,Lei M

更新日期：2017-07-14 00:00:00

abstract：:Drug resistance caused by excessive and indiscriminate antibiotic usage has become a serious public health problem. The need of finding new antibacterial drugs is more urgent than ever before. Tyrosyl-tRNA synthase was proved to be a potent target in combating drug-resistant bacteria. In silico methodologies including...

journal_title：Scientific reports

authors： Li S,Fan J,Peng C,Chang Y,Guo L,Hou J,Huang M,Wu B,Zheng J,Lin L,Xiao G,Chen W,Liao G,Guo J,Sun P

更新日期：2017-09-14 00:00:00

abstract：:Respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and lung infections have critical consequences on mortality and morbidity in humans. The aims of the present study were to examine the mechanisms by which CXCL12 affects MUC1 transcription and airway inflammation, which depend on activa...

journal_title：Scientific reports

authors： Choi IW,Ahn do W,Choi JK,Cha HJ,Ock MS,You E,Rhee S,Kim KC,Choi YH,Song KS

更新日期：2016-06-07 00:00:00

abstract：:The over-expression and aggregation of α-synuclein (αSyn) are linked to the onset and pathology of Parkinson's disease. Native monomeric αSyn exists in an intrinsically disordered ensemble of interconverting conformations, which has made its therapeutic targeting by small molecules highly challenging. Nonetheless, her...

journal_title：Scientific reports

authors： Tóth G,Neumann T,Berthet A,Masliah E,Spencer B,Tao J,Jobling MF,Gardai SJ,Bertoncini CW,Cremades N,Bova M,Ballaron S,Chen XH,Mao W,Nguyen P,Tabios MC,Tambe MA,Rochet JC,Junker HD,Schwizer D,Sekul R,Ott I,Ander

更新日期：2019-11-18 00:00:00

abstract：:At present, there is a growing interest in the study of the neurotropic activity of polyunsaturated fatty acids ethanolamides (N-acylethanolamines). N-docosahexaenoylethanolamine (DHEA, synaptamide) is an endogenous metabolite and structural analogue of anandamide, a widely studied endocannabinoid derived from arachid...

journal_title：Scientific reports

authors： Ponomarenko AI,Tyrtyshnaia AA,Pislyagin EA,Dyuizen IV,Sultanov RM,Manzhulo IV

更新日期：2021-01-12 00:00:00

abstract：:Cognitive impairment is one of the most common problem saffecting older adults. In this study, we investigated whether Tai Chi Chuan and Baduanjin practice can modulate mental control functionand the resting state functional connectivity (rsFC) of the cognitive control network in older adults. Participants in the two ...

journal_title：Scientific reports

authors： Tao J,Chen X,Egorova N,Liu J,Xue X,Wang Q,Zheng G,Li M,Hong W,Sun S,Chen L,Kong J

更新日期：2017-02-07 00:00:00

abstract：:We report on the fabrication of spherical Au spheres by pulsed laser treatment using a KrF excimer laser (248 nm, 25 ns) under ambient conditions as a fast and high throughput fabrication technique. The presented experiments were realized using initial Au layers of 100 nm thickness deposited on optically transparent a...

journal_title：Scientific reports

authors： Schmidl G,Jia G,Gawlik A,Kreusch J,Schmidl F,Dellith J,Dathe A,Lin ZH,Huang JS,Plentz J

更新日期：2018-07-26 00:00:00

abstract：:The controversial anti-proliferative effects of Echinacea purpurea (L.) Moench (Asteraceae) might be related to different plant metabolites contained in plant samples, extracts and products. The influence of bacterial endophytes on the synthesis of bioactive compounds in the medicinal plants has been previously demons...

journal_title：Scientific reports

authors： Maggini V,De Leo M,Granchi C,Tuccinardi T,Mengoni A,Gallo ER,Biffi S,Fani R,Pistelli L,Firenzuoli F,Bogani P

更新日期：2019-07-26 00:00:00

abstract：:Tissue-resident memory T (TRM) cells are characterized by their surface expression of CD69 and can be subdivided in CD103+ and CD103- TRM cells. The origin and functional characteristics of TRM cells in the renal allograft are largely unknown. To determine these features we studied TRM cells in transplant nephrectomie...

journal_title：Scientific reports

authors： de Leur K,Dieterich M,Hesselink DA,Corneth OBJ,Dor FJMF,de Graav GN,Peeters AMA,Mulder A,Kimenai HJAN,Claas FHJ,Clahsen-van Groningen MC,van der Laan LJW,Hendriks RW,Baan CC

更新日期：2019-04-12 00:00:00

abstract：:Enamel proteins form a scaffold for growing hydroxyapatite crystals during enamel formation. They are then almost completely degraded during enamel maturation, resulting in a protein content of only 1% (w/v) in mature enamel. Nevertheless, this small amount of remaining proteins has important effects on the mechanical...

journal_title：Scientific reports

authors： Baumann T,Carvalho TS,Lussi A

更新日期：2015-10-15 00:00:00

abstract：:Although it has been reported that uterine signal transducer and activator of transcription 3 (STAT3) is essential for embryo implantation, the exact roles of uterine epithelial and stromal STAT3 on embryo implantation have not been elucidated. To address this issue, we generated Stat3-floxed/Ltf-iCre (Stat3-eKO), Sta...

journal_title：Scientific reports

authors： Hiraoka T,Hirota Y,Fukui Y,Gebril M,Kaku T,Aikawa S,Hirata T,Akaeda S,Matsuo M,Haraguchi H,Saito-Kanatani M,Shimizu-Hirota R,Takeda N,Yoshino O,Fujii T,Osuga Y

更新日期：2020-09-23 00:00:00

abstract：:In endometriosis, M2 MΦs are dominant in endometriotic lesions, but the actual role of M2 MΦ is unclear. CD206 positive (+) MΦ is classified in one of M2 type MΦs and are known to produce cytokines and chemokines. In the present study, we used CD206 diphtheria toxin receptor mice, which enable to deplete CD206+ cells ...

journal_title：Scientific reports

authors： Ono Y,Yoshino O,Hiraoka T,Sato E,Furue A,Nawaz A,Hatta H,Fukushi Y,Wada S,Tobe K,Hirota Y,Osuga Y,Unno N,Saito S

更新日期：2021-01-13 00:00:00

abstract：:As a source of genetic variation, almond germplasm resources are of great significance in breeding. To better reveal the mutation characteristics and evolution patterns of the almond chloroplast (cp) genome, the complete cp genomes from six almond species were analyzed. The lengths of the chloroplast genome of the six...

journal_title：Scientific reports

authors： Wang W,Yang T,Wang HL,Li ZJ,Ni JW,Su S,Xu XQ

更新日期：2020-06-23 00:00:00

abstract：:HIV subtypes or clades differentially induce HIV-associated neurocognitive disorders (HAND) and substance abuse is known to accelerate HIV disease progression. The HIV-1 envelope protein gp120 plays a major role in binding and budding in the central nervous system (CNS) and impacts dopaminergic functions. However, the...

journal_title：Scientific reports

authors： Samikkannu T,Rao KVK,Salam AAA,Atluri VSR,Kaftanovskaya EM,Agudelo M,Perez S,Yoo C,Raymond AD,Ding H,Nair MPN

更新日期：2015-06-09 00:00:00

abstract：:Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses revealed a marked increase in extracellular matri...

journal_title：Scientific reports

authors： Wang J,Chen L,Chen B,Meliton A,Liu SQ,Shi Y,Liu T,Deb DK,Solway J,Li YC

更新日期：2015-10-23 00:00:00

abstract：:Platelet transfusions can cause adverse reactions in their recipients, including transfusion-related acute lung injury (TRALI). The pathophysiology of TRALI depends on a number of signaling pathways and the inflammatory role played by blood platelets remains controversial. Platelets are important in inflammation, part...

journal_title：Scientific reports

authors： Tariket S,Hamzeh-Cognasse H,Laradi S,Arthaud CA,Eyraud MA,Bourlet T,Berthelot P,Garraud O,Cognasse F

更新日期：2019-08-29 00:00:00

abstract：:In zebrafish, the role of matrix metalloproteinases (MMPs) in the inflammatory phase of heart regeneration following cryoinjury remains poorly understood. Here, we demonstrated an increase in MMP enzymatic activity and elevated expression of mmp9 and mmp13 in the injured area (IA) of hearts from as early as 1 day post...

journal_title：Scientific reports

authors： Xu S,Webb SE,Lau TCK,Cheng SH

更新日期：2018-05-08 00:00:00

abstract：:In-resin CLEM of Epon embedded samples can greatly simplify the correlation of fluorescent images with electron micrographs. The usefulness of this technique is limited at present by the low number of fluorescent proteins that resist CLEM processing. Additionally, no study has reported the possibility of two-color in-...

journal_title：Scientific reports

authors： Tanida I,Furuta Y,Yamaguchi J,Kakuta S,Oliva Trejo JA,Uchiyama Y

更新日期：2020-12-14 00:00:00

abstract：:When we feel sad or depressed, our face invariably "drops". Conversely, when we try to cheer someone up, we might tell them "keep your smile up", so presupposing that modifying the configuration of their facial muscles will enhance their mood. A crucial assumption that underpins this hypothesis is that mental states a...

journal_title：Scientific reports

authors： Bulnes LC,Mariën P,Vandekerckhove M,Cleeremans A

更新日期：2019-08-13 00:00:00

abstract：:Here we present a set of measurements using Differential Scanning Fluorimetry (DSF) as an inexpensive, high throughput screening method to investigate the folding of silk protein molecules as they abandon their first native melt conformation, dehydrate and denature into their final solid filament conformation. Our fir...

journal_title：Scientific reports

authors： Vollrath F,Hawkins N,Porter D,Holland C,Boulet-Audet M

更新日期：2014-07-09 00:00:00

abstract：:Gold nanoparticles (GNP) have been intensively investigated for applications in cancer imaging and therapy. Most imaging studies focused on microscopic imaging. Their potential as optical imaging probes for whole body small animal imaging has rarely been explored. Taking advantage of their surface plasmon resonance (S...

journal_title：Scientific reports

authors： Xu K,Shi J,Pourmand A,Udayakumar TS,Dogan N,Zhao W,Pollack A,Yang Y

更新日期：2018-06-19 00:00:00