Wave manipulation with magnetically tunable metasurfaces.

abstract：:We have succeeded in developing hollow branching structure in vitro commonly observed in lung airway using primary lung airway epithelial cells. Cell concentration gradient is the key factor that determines production of the branching cellular structures, as optimization of this component removes the need for heteroty...

journal_title：Scientific reports

authors： Hagiwara M,Peng F,Ho CM

更新日期：2015-01-27 00:00:00

abstract：:Drug resistance in Clostridioides difficile becomes a public health concern worldwide, especially as the hypervirulent strains show decreased susceptibility to the first-line antibiotics for C. difficile treatment. Therefore, the simultaneous discovery and development of new compounds to fight this pathogen are urgent...

journal_title：Scientific reports

authors： Phanchana M,Phetruen T,Harnvoravongchai P,Raksat P,Ounjai P,Chankhamhaengdecha S,Janvilisri T

更新日期：2020-04-16 00:00:00

abstract：:Sex differentiation is a puzzling problem in fish due to the variety of reproductive systems and the flexibility of their sex determination mechanisms. The Sparidae, a teleost family, reflects this remarkable diversity of sexual mechanisms found in fish. Our aim was to capture the transcriptomic signature of different...

journal_title：Scientific reports

authors： Tsakogiannis A,Manousaki T,Lagnel J,Sterioti A,Pavlidis M,Papandroulakis N,Mylonas CC,Tsigenopoulos CS

更新日期：2018-02-23 00:00:00

abstract：:The long-standing challenge for forming Al-based BMGs and their matrix composites with a critical size larger than 1 mm have not been answered over the past three decades. In this paper, we reported formation of a series of BMG matrix composites which contain a high Al content up to 55 at.%. These composites can be ca...

journal_title：Scientific reports

authors： Chen ZP,Gao JE,Wu Y,Wang H,Liu XJ,Lu ZP

更新日期：2013-11-27 00:00:00

abstract：:Technological improvements have resulted in increased discovery of new microRNAs (miRNAs) and refinement and enrichment of existing miRNA families. miRNA families are important because they suggest a common sequence or structure configuration in sets of genes that hint to a shared function. Exploratory tools to enhanc...

journal_title：Scientific reports

authors： Kamanu TK,Radovanovic A,Archer JA,Bajic VB

更新日期：2013-10-15 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is usually preceded by the oral premalignant lesions, mainly oral leukoplakia (OLK) after repeated insults of carcinogens, tobacco. B(a)P and DMBA are key carcinogens in tobacco smoke. In the present study, for the first time we established the cancerous cell line OSCC-BD induced by...

journal_title：Scientific reports

authors： Dong Y,Zhao Q,Ma X,Ma G,Liu C,Chen Z,Yu L,Liu X,Zhang Y,Shao S,Xiao J,Li J,Zhang W,Fu M,Dong L,Yang X,Guo X,Xue L,Fang F,Zhan Q,Zhang L

更新日期：2015-08-03 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Makino E,Klodnitsky H,Leonard J,Lillie J,Lund TC,Marshall J,Nietupski J,Orchard PJ,Miller WP,Phaneuf C,Tietz D,Varban ML,Donovan M,Belenki A

更新日期：2018-03-19 00:00:00

abstract：:This work reports the remarkable effect of reversible gas molecular sieving for high temperature gas separation from cobalt doped ethoxy polysiloxane (CoES40) membranes. This effect stemmed from alternating the reducing and oxidising (redox) state of the cobalt particles embedded in the ES40 matrix. The reduced membra...

journal_title：Scientific reports

authors： Miller CR,Wang DK,Smart S,Diniz da Costa JC

更新日期：2013-01-01 00:00:00

abstract：:Many aspects of song learning in songbirds resemble characteristics of speech acquisition in humans. Genetic, anatomical and behavioural parallels have most recently been extended with demonstrated similarities in hemispheric dominance between humans and songbirds: the avian higher order auditory cortex is left-latera...

journal_title：Scientific reports

authors： Chirathivat N,Raja SC,Gobes SM

更新日期：2015-06-22 00:00:00

abstract：:Recent whole-exome sequencing (WES) studies demonstrated that TRAIP is associated with primordial dwarfism. Although TRAIP was partially studied in mitosis, its function in oocyte meiosis remained unknown. In this study, we investigated the roles of TRAIP during mouse oocyte meiosis. TRAIP was stably expressed during ...

journal_title：Scientific reports

authors： Yuan YF,Ren YX,Yuan P,Yan LY,Qiao J

更新日期：2016-07-11 00:00:00

abstract：:Retinitis pigmentosa (RP) is a heterogeneous group of inherited disorders caused by mutations in a variety of genes that are mostly expressed by rod cells, which results in initial death of rod photoreceptors followed by gradual death of cone photoreceptors. RP is currently untreatable and usually leads to partial or ...

journal_title：Scientific reports

authors： Wang K,Xiao J,Peng B,Xing F,So KF,Tipoe GL,Lin B

更新日期：2014-12-23 00:00:00

abstract：:Most published sleep studies use three species: human, house mouse, or Norway rat. The degree to which data from these species captures variability in mammalian sleep remains unclear. To gain insight into mammalian sleep diversity, we examined sleep architecture in the spiny basal murid rodent Acomys cahirinus. First,...

journal_title：Scientific reports

authors： Wang C,Guerriero LE,Huffman DM,Ajwad AA,Brooks TC,Sunderam S,Seifert AW,O'Hara BF

更新日期：2020-07-02 00:00:00

abstract：:The ability to shape the index profile of optical fibers holds the key to fully flexible engineering of their optical properties and future applications. We present a new approach for the development of a graded index fused silica fiber based on core nanostructurization. A graded index core is obtained by means of dis...

journal_title：Scientific reports

authors： Anuszkiewicz A,Kasztelanic R,Filipkowski A,Stepniewski G,Stefaniuk T,Siwicki B,Pysz D,Klimczak M,Buczynski R

更新日期：2018-08-17 00:00:00

abstract：:Fitness-related costs of evolving insecticide resistance have been reported in a number of insect species, but the interplay between evolutionary adaptation to insecticide pressure and variable environmental conditions has received little attention. We provisioned nymphs from three German cockroach (Blattella germanic...

journal_title：Scientific reports

authors： Jensen K,Ko AE,Schal C,Silverman J

更新日期：2016-06-27 00:00:00

abstract：:In this study, the effects of different feeding frequencies on the growth and the expression of genes in the GH/IGF axis were assessed in juvenile Chinese sturgeon. The newly hatched Chinese sturgeons were bred for 38 days at three different feeding frequencies groups (feeding frequency of two times a day, TWD; three ...

journal_title：Scientific reports

authors： Hu Y,Xiao K,Yang J,Liu X,Wang B,Zeng Q,Du H

更新日期：2020-10-15 00:00:00

abstract：:Long Terminal Repeats (LTRs) are nearly identical DNA sequences found at either end of Human Endogenous Retroviruses (HERVs). The high sequence similarity that exists among different LTRs suggests they could be substrate of ectopic gene conversion events. To understand the extent to which gene conversion occurs and to...

journal_title：Scientific reports

authors： Trombetta B,Fantini G,D'Atanasio E,Sellitto D,Cruciani F

更新日期：2016-06-27 00:00:00

abstract：:The 6SA-CASSCF(10, 10)/6-31G (d, p) quantum chemistry method has been applied to perform on-the-fly trajectory surface hopping simulation with global switching algorithm and to explore excited-state intramolecular proton transfer reactions for the o-nitrophenol molecule within low-lying electronic singlet states (S0 a...

journal_title：Scientific reports

authors： Xu C,Yu L,Zhu C,Yu J,Cao Z

更新日期：2016-05-25 00:00:00

abstract：:Domoic acid (DA, 1), a potent neurotoxin that causes amnesic shellfish poisoning, has been found in diatoms and red algae. While biosynthetic pathway towards DA from geranyl diphosphate and L-glutamate has been previously proposed, its late stage is still unclear. Here, six novel DA related compounds, 7'-methyl-isodom...

journal_title：Scientific reports

authors： Maeno Y,Kotaki Y,Terada R,Cho Y,Konoki K,Yotsu-Yamashita M

更新日期：2018-01-10 00:00:00

abstract：:Numerous studies have investigated the association between eosinophilia and clinical outcome of patients with chronic obstructive pulmonary disease (COPD) but the evidence is conflicting. We conducted a pooled analysis of outcome measures comparing eosinophilic and non-eosinophilic COPD patients. We searched articles ...

journal_title：Scientific reports

authors： Ho J,He W,Chan MTV,Tse G,Liu T,Wong SH,Leung CCH,Wong WT,Tsang S,Zhang L,Chan RYP,Gin T,Leung J,Lau BWM,Wu WKK,Ngai SPC

更新日期：2017-10-18 00:00:00

abstract：:Transcription factors (TFs) binding to specific DNA sequences or motifs, are elementary to the regulation of transcription. The gene is regulated by a combination of TFs in close proximity. Analysis of co-TFs is an important problem in understanding the mechanism of transcriptional regulation. Recently, ChIP-seq in ma...

journal_title：Scientific reports

authors： Pan G,Tang J,Guo F

更新日期：2017-02-27 00:00:00

abstract：:Novel pain killers without adverse effects are urgently needed. Opioids induce central and intestinal side effects such as respiratory depression, sedation, addiction, and constipation. We have recently shown that a newly designed agonist with a reduced acid dissociation constant (pKa) abolished pain by selectively ac...

journal_title：Scientific reports

authors： Spahn V,Del Vecchio G,Rodriguez-Gaztelumendi A,Temp J,Labuz D,Kloner M,Reidelbach M,Machelska H,Weber M,Stein C

更新日期：2018-06-12 00:00:00

abstract：:Recombination is crucial for biological evolution, which provides many new combinations of genetic diversity. Accurate identification of recombination spots is useful for DNA function study. To improve the prediction accuracy, researchers have proposed several computational methods for recombination spot identificatio...

journal_title：Scientific reports

authors： Wang R,Xu Y,Liu B

更新日期：2016-03-31 00:00:00

abstract：:State-of-the-art of preoperative planning for forearm orthopaedic surgeries is currently limited to simple bone procedures. The increasing interest of clinicians for more comprehensive analysis of complex pathologies often requires dynamic models, able to include the soft tissue influence into the preoperative process...

journal_title：Scientific reports

authors： Carrillo F,Suter S,Casari FA,Sutter R,Nagy L,Snedeker JG,Fürnstahl P

更新日期：2020-04-14 00:00:00

abstract：:Stress and recovery from stress significantly affect interactions between the central nervous system, endocrine pathways, and the immune system. However, the influence of acute stress on circulating immune-endocrine mediators in humans is not well known. Using a double-blind, randomized study design, we administered a...

journal_title：Scientific reports

authors： Koelsch S,Boehlig A,Hohenadel M,Nitsche I,Bauer K,Sack U

更新日期：2016-03-29 00:00:00

abstract：:Ulvan, which is one of the major structural polysaccharides of the cell walls of green macroalgae, is degraded by ulvan lyases via the β-elimination mechanism with the release of oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (∆) at the non-reducing end. These ulvan lyases belong ...

journal_title：Scientific reports

authors： Konasani VR,Jin C,Karlsson NG,Albers E

更新日期：2018-10-02 00:00:00

abstract：:The aim is to design a patient-specific instrument (PSI) for multilevel cervical pedicle screw placement from C2 to C7, as well as verifying reliability and reproducibility. Computed tomography (CT) scans were obtained from 7 cadaveric cervical spines. Using Mimics software, semiautomatic segmentation was performed fo...

journal_title：Scientific reports

authors： Sallent A,Ramírez M,Catalá J,Rodríguez-Baeza A,Bagó J,de Albert M,Vélez R

更新日期：2019-10-30 00:00:00

abstract：:Although silicon (Si) has been widely reported to alleviate plant nutrient deficiency, the underlying mechanism in potassium (K) deficiency is poorly understood. In this study, sorghum seedlings were treated with Si under a K deficiency condition for 15 days. Under control conditions, plant growth was not affected by ...

journal_title：Scientific reports

authors： Chen D,Cao B,Wang S,Liu P,Deng X,Yin L,Zhang S

更新日期：2016-03-10 00:00:00

abstract：:The G-protein bile acid receptor 1 (GPBAR1) has emerged in the last decade as prominent target for the treatment of metabolic and inflammatory diseases including type 2 diabetes, obesity, and non-alcoholic steatohepatitis. To date numerous bile acid derivatives have been identified as GPBAR1 agonists, however their cl...

journal_title：Scientific reports

authors： Di Leva FS,Festa C,Carino A,De Marino S,Marchianò S,Di Marino D,Finamore C,Monti MC,Zampella A,Fiorucci S,Limongelli V

更新日期：2019-02-21 00:00:00

abstract：:The control of structural and chemical transitions in bimetallic nanoalloys at finite temperatures is one of the challenges for their use in advanced applications. Comparing Nested Sampling and Molecular Dynamics simulations, we investigate the phase changes of CuPt nanoalloys with the aim to elucidate the role of kin...

journal_title：Scientific reports

authors： Rossi K,Pártay LB,Csányi G,Baletto F

更新日期：2018-06-14 00:00:00

abstract：:Small molecule based targeted therapies for the treatment of metastatic melanoma hold promise but responses are often not durable, and tumors frequently relapse. Response to adoptive cell transfer (ACT)-based immunotherapy in melanoma patients are durable but patients develop resistance primarily due to loss of antige...

journal_title：Scientific reports

authors： Dextras C,Dashnyam M,Griner LAM,Sundaresan J,Chim B,Yu Z,Vodnala S,Lee CR,Hu X,Southall N,Marugan JJ,Jadhav A,Restifo NP,Acquavella N,Ferrer M,Singh A

更新日期：2020-03-30 00:00:00