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Nanobeam X-ray fluorescence and diffraction computed tomography on human bone with a resolution better than 120 nm.

Abstract：

:Studying nanostructured hierarchical materials such as the biomineralized bone is challenging due to their complex 3D structures that call for high spatial resolution. One route to study such materials is X-ray powder diffraction computed tomography (XRD-CT) that reveals the 3D distribution of crystalline phases and X-ray fluorescence computed tomography (XRF-CT) that provides element distributions. However, the spatial resolution of XRD-CT has thus far been limited. Here we demonstrate better than 120 nm 3D resolution on human bone in XRD-CT and XRF-CT measured simultaneously using X-ray nanobeams. The results pave the way for nanoscale 3D characterization of nanocrystalline composites like bone at unprecedented detail.

journal_name

J Struct Biol

journal_title

Journal of structural biology

authors

Palle J,Wittig NK,Kubec A,Niese S,Rosenthal M,Burghammer M,Grünewald TA,Birkedal H

doi

10.1016/j.jsb.2020.107631

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

107631

issue

3

eissn

1047-8477

issn

1095-8657

pii

S1047-8477(20)30204-5

journal_volume

212

pub_type

杂志文章

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