Abstract：
:The interplay between structure and function is critical in the understanding of complex systems, their dynamics and their behavior. We investigated the interplay between structural and functional networks by means of the differential identifiability framework, which here quantifies the ability of identifying a particular network structure based on (1) the observation of its functional network and (2) the comparison with a prior observation under different initial conditions. We carried out an experiment consisting of the construction of [Formula: see text] different structural networks composed of [Formula: see text] nonlinear electronic circuits and studied the regions where network structures are identifiable. Specifically, we analyzed how differential identifiability is related to the coupling strength between dynamical units (modifying the level of synchronization) and what are the consequences of increasing the amount of noise existing in the functional networks. We observed that differential identifiability reaches its highest value for low to intermediate coupling strengths. Furthermore, it is possible to increase the identifiability parameter by including a principal component analysis in the comparison of functional networks, being especially beneficial for scenarios where noise reaches intermediate levels. Finally, we showed that the regime of the parameter space where differential identifiability is the highest is highly overlapped with the region where structural and functional networks correlate the most.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Vera-Ávila VP,Sevilla-Escoboza R,Goñi J,Rivera-Durón RR,Buldú JMdoi
10.1038/s41598-020-71373-4subject
Has Abstractpub_date
2020-09-04 00:00:00pages
14668issue
1issn
2045-2322pii
10.1038/s41598-020-71373-4journal_volume
10pub_type
杂志文章abstract：:HIV subtypes or clades differentially induce HIV-associated neurocognitive disorders (HAND) and substance abuse is known to accelerate HIV disease progression. The HIV-1 envelope protein gp120 plays a major role in binding and budding in the central nervous system (CNS) and impacts dopaminergic functions. However, the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11130
更新日期：2015-06-09 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-59134-9
更新日期：2020-02-06 00:00:00
abstract：:The advantages of the digital PCR technology are already well documented until now. One way to achieve better cost efficiency of the technique is to use it in a multiplexing strategy. Droplet digital PCR platforms, which include two fluorescence filters, support at least duplex reactions and with some developments and...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35451
更新日期：2016-10-14 00:00:00
abstract：:There are lack of studies regarding the effects of microbial diversity on specific soil functions, such as pesticides degradation. This study evaluated the role of bacterial community diversity and biochar on chlorothalonil (CTN) degradation, using 'dilution to extinction' approach, PCR-DGGE/16S rRNA gene technique, a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14803-0
更新日期：2017-11-07 00:00:00
abstract：:Here we present an ultraviolet responsive inorganic-organic hybrid solar cell based on titania/poly(3-hexylthiophene) (TiO(2)/P3HT) heterojuction. In this solar cell, TiO(2) is an ultraviolet light absorber and electronic conductor, P3HT is a hole conductor, the light-to-electrical conversion is realized by the cooper...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01283
更新日期：2013-01-01 00:00:00
abstract：:The objective was to measure the association between badger culling and bovine tuberculosis (TB) incidents in cattle herds in three areas of England between 2013-2017 (Gloucestershire and Somerset) and 2015-2017 (Dorset). Farming industry-selected licensed culling areas were matched to comparison areas. A TB incident ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49957-6
更新日期：2019-10-11 00:00:00
abstract：:Nitrate molten salts are extensively used for sensible heat storage in Concentrated Solar Power (CSP) plants and thermal energy storage (TES) systems. They are the most promising materials for latent heat storage applications. By combining classical molecular dynamics and differential scanning calorimetry experiments,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28641-1
更新日期：2018-07-11 00:00:00
abstract：:The secretion of glucagon by pancreatic alpha cells is regulated by a number of external and intrinsic factors. While the electrophysiological processes linking a lowering of glucose concentrations to an increased glucagon release are well characterized, the evidence for the identity and function of the glucose sensor...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76863-z
更新日期：2020-11-19 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-28651-z
更新日期：2018-07-05 00:00:00
abstract：:Compared with natural materials, chiral metamaterials have been demonstrated with orders of magnitude stronger chiroptical response, which provides the basis for applications such as ultracompact polarization components and plasmonic-enhanced biosensing. Terahertz chiral metamaterials that allow dynamic polarization c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18472-x
更新日期：2018-01-09 00:00:00
abstract：:The sensitivity of localized surface plasmon resonance (LSPR) of metal nanostructures to adsorbates lends itself to a powerful class of label-free biosensors. Optical properties of plasmonic nanostructures are dependent on the geometrical features and the local dielectric environment. The exponential decay of the sens...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16206
更新日期：2015-11-10 00:00:00
abstract：:Structural neuroimaging studies of posttraumatic stress disorder (PTSD) have typically reported reduced cortical thickness (CT) and gray matter volume (GMV) in subcortical structures and networks involved in memory retrieval, emotional processing and regulation, and fear acquisition and extinction. Although PTSD is mo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80776-2
更新日期：2021-01-19 00:00:00
abstract：:Nitric oxide (NO), a vascular signaling molecule, is primarily produced by endothelial NO synthase. Recently, a functional endothelial NO synthase (eNOS) was described in red blood cells (RBC). The RBC-eNOS contributes to the intravascular NO pool and regulates physiological functions. However the regulatory mechanism...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26935
更新日期：2016-06-27 00:00:00
abstract：:Training the capacity to self-generate emotions can be a potent "vaccine" against negative stressors and be an effective intervention for affective psychopathology. However, due to a lack of knowledge about sources of individual differences in generation abilities, it is unclear how to optimally design such interventi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20380-7
更新日期：2018-01-31 00:00:00
abstract：:In this manuscript, we studied the thermal properties of hundred-watt fiber laser oscillator by real-time in-situ distributed temperature measurement. Optical frequency domain reflectometry (OFDR) was introduced to measure the temperature distribution of gain fiber core. The fiber laser oscillator operated at 1080 nm ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66470-3
更新日期：2020-06-02 00:00:00
abstract：:Evaluating and tuning the properties of two-dimensional (2D) materials is a major focus of advancing 2D science and technology. While many claim that the photonic properties of a 2D layer provide evidence that the material is "high quality", this may not be true for electronic performance. In this work, we deconvolute...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16970-6
更新日期：2017-12-05 00:00:00
abstract：:Various folk remedies employ certain odorous compounds with analgesic effects. In fact, linalool, a monoterpene alcohol found in lavender extracts, has been found to attenuate pain responses via subcutaneous, intraperitoneal, intrathecal, and oral administration. However, the analgesic effects of odorous compounds med...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37129
更新日期：2016-11-15 00:00:00
abstract：:Mechanistic studies of deregulated ERG in prostate cancer and other cancers continue to enhance its role in cancer biology and its utility as a biomarker and therapeutic target. Here, we show that ERG, through its physical interaction with androgen receptor, induces AR aggregation and endoplasmic reticulum stress in t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01187-4
更新日期：2017-04-24 00:00:00
abstract：:A connection between airway and gut microbiota related to allergen exposure in childhood allergies was not well addressed. We aimed to identify the microbiota alterations in the airway and gut related to mite-specific IgE responses in young children with airway allergies. This study enrolled 60 children, including 38 ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-70528-7
更新日期：2020-08-10 00:00:00
abstract：:The band structures of dilute-As AlNAs alloys with As composition ranging from 0% up to 12.5% are studied by using First-Principle Density Functional Theory (DFT) calculation. The energy band gap shows remarkable reduction from 6.19 eV to 3.87 eV with small amount of As content in the AlNAs alloy, which covers the dee...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22215
更新日期：2016-02-24 00:00:00
abstract：:Coronin7 (CRN7) stabilizes F-actin and is a regulator of processes associated with the actin cytoskeleton. Its loss leads to defects in phagocytosis, motility and development. It harbors a CRIB (Cdc42- and Rac-interactive binding) domain in each of its WD repeat domains which bind to Rac GTPases preferably in their GD...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14437
更新日期：2015-09-28 00:00:00
abstract：:A neurogenic pathway, involving airway TRPV-1, has been implicated in acute cardiovascular events occurring after peaks of air pollution. We tested whether inhaled prostaglandin-E2 (PGE2) and bradykinin (BK) regulate TRPV-1 activity in vivo by changing cough response to capsaicin (CPS) and affecting heart rate variabi...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41598-020-72062-y
更新日期：2020-09-16 00:00:00
abstract：:We conduct textual analysis of a sample of more than 200,000 papers written on HIV/AIDS during the past three decades. Using the Latent Dirichlet Allocation method, we disentangle studies that address behavioral and social aspects from other studies and measure the trends of different topics as related to HIV/AIDS. We...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-04527-6
更新日期：2017-06-23 00:00:00
abstract：:Gyroviruses (GyVs) are small, single-stranded, circular DNA viruses in the genus Gyrovirus, which consists of the chicken anemia virus (CAV) prototype and nine other viral species. These different GyV species have been reported in chickens, humans, mice, and companion animals. To date, CAV has been identified in the f...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49955-8
更新日期：2019-09-16 00:00:00
abstract：:Raman spectroscopy is a powerful analytical method that allows deposited and/or immobilized cells to be evaluated without complex sample preparation or labeling. However, a main limitation of Raman spectroscopy in cell analysis is the extremely weak Raman intensity that results in low signal to noise ratios. Therefore...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13150
更新日期：2015-08-27 00:00:00
abstract：:Experimental evidence has shown that some of the human endogenous hormones significantly affect drug efficacy. Since hormone status varies with individual physiological states, it is essential to understand the interplay of hormones and drugs for precision medicine. Here, we developed an in silico method to predict in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16855-8
更新日期：2017-11-30 00:00:00
abstract：:Proteins are highly dynamic entities attaining a myriad of different conformations. Protein side chains change their states during dynamics, causing clashes that are propagated at distal sites. A convenient formalism to analyze protein dynamics is based on network theory using Protein Structure Networks (PSNs). Despit...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01498-6
更新日期：2017-06-06 00:00:00
abstract：:We propose to use Rabi oscillation as a probe to view the fractional Josepshon relation (FJR) associated with Majorana bound states (MBSs) expected in one-dimensional topological superconductors. The system consists of a quantum dot (QD) and an rf-SQUID with MBSs at the Josephson junction. Rabi oscillations between en...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11686
更新日期：2015-07-08 00:00:00
abstract：:The CRISPR/Cas9 system is a powerful method of editing genes by randomly introducing errors into the target sites. Here, we describe a CRISPR-based test for gene essentiality (CRISPR-E test) that allows the identification of essential genes. Specifically, we use sgRNA-mediated CRISPR/Cas9 to target the open reading fr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71690-8
更新日期：2020-09-08 00:00:00
abstract：:In glaucoma, retinal ganglion cells degenerate progressively, leading to visual field loss and blindness. Presently, the only treatment strategy for glaucoma is lowering the intraocular pressure. However, there are cases in which patients develop progressive visual field loss even though their intraocular pressures ar...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78731-2
更新日期：2020-12-10 00:00:00
