Abstract:
:The Amazon river basin receives ~2000 mm of precipitation annually and contributes ~17% of global river freshwater input to the oceans; its hydroclimatic variations can exert profound impacts on the marine ecosystem in the Amazon plume region (APR) and have potential far-reaching influences on hydroclimate over the tropical Atlantic. Here, we show that an amplified seasonal cycle of Amazonia precipitation, represented by the annual difference between maximum and minimum values, during the period 1979-2018, leads to enhanced seasonalities in both Amazon river discharge and APR ocean salinity. An atmospheric moisture budget analysis shows that these enhanced seasonal cycles are associated with similar amplifications in the atmospheric vertical and horizontal moisture advections. Hierarchical sensitivity experiments using global climate models quantify the relationships of these enhanced seasonalities. The results suggest that an intensified hydroclimatological cycle may develop in the Amazonia atmosphere-land-ocean coupled system, favouring more extreme terrestrial and marine conditions.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Liang YC,Lo MH,Lan CW,Seo H,Ummenhofer CC,Yeager S,Wu RJ,Steffen JDdoi
10.1038/s41467-020-18187-0subject
Has Abstractpub_date
2020-09-01 00:00:00pages
4390issue
1issn
2041-1723pii
10.1038/s41467-020-18187-0journal_volume
11pub_type
杂志文章abstract::Bacterial Type III Secretion Systems deliver effectors into host cells to manipulate cellular processes to the advantage of the pathogen. Many host targets of these effectors are found on membranes. Therefore, to identify their targets, effectors often use specialized membrane-localization domains to localize to appro...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3973
更新日期:2013-01-01 00:00:00
abstract::Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive analytical technique with molecular specificity, making it an ideal candidate for therapeutic drug monitoring (TDM). However, in critical diagnostic media including blood, nonspecific protein adsorption coupled with weak surface affinities and small Raman...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13437
更新日期:2016-11-11 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/s41467-019-13141-1
更新日期:2019-11-08 00:00:00
abstract::The practices of synthetic biology are being integrated into 'multiscale' designs enabling two-way communication across organic and inorganic information substrates in biological, digital and cyber-physical system integrations. Novel applications of 'bio-informational' engineering will arise in environmental monitorin...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/s41467-020-20764-2
更新日期:2021-01-15 00:00:00
abstract::Akt2 and its downstream effectors mediate insulin-stimulated GLUT4-storage vesicle (GSV) translocation and fusion with the plasma membrane (PM). Using mass spectrometry, we identify actin-capping protein Tropomodulin 3 (Tmod3) as an Akt2-interacting partner in 3T3-L1 adipocytes. We demonstrate that Tmod3 is phosphoryl...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6951
更新日期:2015-01-09 00:00:00
abstract::Among calcareous nannofossils, important primary producers in Jurassic and Cretaceous oceans, nannoconids were carbonate rock-forming organisms. During the late Barremian and early Aptian (~126 to 122 million years ago), nannoconids went through a crisis culminating during the Oceanic Anoxic Event 1a. Here we present ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2698
更新日期:2013-01-01 00:00:00
abstract::Quantifying chemical compositions around nanovoids is a fundamental task for research and development of various materials. Atom probe tomography (APT) and scanning transmission electron microscopy (STEM) are currently the most suitable tools because of their ability to probe materials at the nanoscale. Both technique...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14832-w
更新日期:2020-02-24 00:00:00
abstract::As children grow, they gradually learn how to make decisions independently. However, decisions like choosing healthy but less-tasty foods can be challenging for children whose self-regulation and executive cognitive functions are still maturing. We propose a computational decision-making process in which children esti...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11700
更新日期:2016-05-24 00:00:00
abstract::Non-CG methylation has been associated with stemness regulation in embryonic stem cells. By comparing differentially expressed genes affected by non-CG methylation between tumour and corresponding non-tumour tissues in oesophageal squamous cell carcinoma (OSCC), we find that Integrin α7 (ITGA7) is characterized as a p...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13568
更新日期:2016-12-07 00:00:00
abstract::Everyone experiences common events differently. This leads to personal memories that presumably provide neural signatures of individual identity when events are reimagined. We present initial evidence that these signatures can be read from brain activity. To do this, we progress beyond previous work that has deployed ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19630-y
更新日期:2020-11-20 00:00:00
abstract::How do descending inputs from the brain control leg motor circuits to change how an animal walks? Conceptually, descending neurons are thought to function either as command-type neurons, in which a single type of descending neuron exerts a high-level control to elicit a coordinated change in motor output, or through a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19936-x
更新日期:2020-12-02 00:00:00
abstract::In reducing the high operating temperatures (≥800 °C) of solid-oxide fuel cells, use of protonic ceramics as an alternative electrolyte material is attractive due to their high conductivity and low activation energy in a low-temperature regime (≤600 °C). Among many protonic ceramics, yttrium-doped barium zirconate has...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14553
更新日期:2017-02-23 00:00:00
abstract::Ellagitannins are a family of polyphenols containing more than 1,000 natural products. Nearly 40% of these compounds contain a highly oxygenated diaryl ether that is one of the most critical elements to their structural diversity. Here, we report a unified strategy for the synthesis of highly oxygenated diaryl ethers ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4478
更新日期:2014-03-24 00:00:00
abstract::The gut-derived orexigenic peptide hormone ghrelin enhances neuronal firing in the substantia nigra pars compacta, where dopaminergic neurons modulate the function of the nigrostriatal system for motor coordination. Here we describe a novel mechanism by which ghrelin enhances firing of nigral dopaminergic neurons by i...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2439
更新日期:2013-01-01 00:00:00
abstract::The evolution of the seawater oxygen isotopic composition (δ18O) through geological time remains controversial. Yet, the past δ18Oseawater is key to assess past seawater temperatures, providing insights into past climate change and life evolution. Here we provide a new and unprecedentedly precise δ18O value of -1.33 ±...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03890-w
更新日期:2018-04-13 00:00:00
abstract::MCR-1 is a lipid A modifying enzyme that confers resistance to the antibiotic colistin. Here, we analyse the impact of MCR-1 expression on E. coli morphology, fitness, competitiveness, immune stimulation and virulence. Increased expression of mcr-1 results in decreased growth rate, cell viability, competitive ability ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02149-0
更新日期:2017-12-12 00:00:00
abstract::Cell fate determination requires the cooperation between extrinsic signals and intrinsic molecules including transcription factors as well as epigenetic regulators. Nevertheless, how neural fate commitment is regulated by epigenetic modifications remains largely unclear. Here we show that transient histone deacetylati...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7830
更新日期:2015-04-23 00:00:00
abstract::Scleroderma is an autoimmune rheumatic disorder accompanied by severe fibrosis in skin and other internal organs. During scleroderma progression, resident fibroblasts undergo activation and convert to α-smooth muscle actin (α-SMA) expressing myofibroblasts (MFBs) with increased capacity to synthesize collagens and fib...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09101-4
更新日期:2019-03-08 00:00:00
abstract::Observing the crucial first few femtoseconds of photochemical reactions requires tools typically not available in the femtochemistry toolkit. Such dynamics are now within reach with the instruments provided by attosecond science. Here, we apply experimental and theoretical methods to assess the ultrafast nonadiabatic ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01133-y
更新日期:2017-10-18 00:00:00
abstract::Many bacteria can exchange genetic material through horizontal gene transfer (HGT) mediated by plasmids and plasmid-borne transposable elements. Here, we study the population structure and dynamics of over 10,000 bacterial plasmids, by quantifying their genetic similarities and reconstructing a network based on their ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16282-w
更新日期:2020-05-15 00:00:00
abstract::Inversions are one type of structural variants linked to phenotypic differences and adaptation in multiple organisms. However, there is still very little information about polymorphic inversions in the human genome due to the difficulty of their detection. Here, we develop a new high-throughput genotyping method based...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12173-x
更新日期:2019-09-17 00:00:00
abstract::The coupling of ordered electronic phases with lattice, spin, and orbital degrees of freedom are of central interest in strongly correlated systems. Their interplay has been intensively studied from femtosecond to picosecond time scales, while their dynamics beyond nanoseconds are usually assumed to follow lattice coo...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-04199-4
更新日期:2018-05-04 00:00:00
abstract::Long-chain alcohols synthesis (LAS, C5+OH) from syngas provides a promising route for the conversion of coal/biomass/natural gas into high-value chemicals. Cu-Fe binary catalysts, with the merits of cost effectiveness and high CO conversion, have attracted considerable attention. Here we report a nano-construct of a F...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13691-4
更新日期:2020-01-03 00:00:00
abstract::In cancer metastasis, various environmental stressors attack the disseminating cells. The successful colonization of cancer cells in secondary sites therefore requires the ability of the cells to avoid the consequences of such exposure to the stressors. Here we show that orthotopic transplantation of a CD44 variant is...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1892
更新日期:2012-06-06 00:00:00
abstract::Non-Abelian quasiparticles have been predicted to exist in a variety of condensed matter systems. Their defining property is that an adiabatic braid between two of them results in a non-trivial change of the quantum state of the system. The simplest non-Abelian quasiparticles--the Majorana bound states--can occur in o...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10395
更新日期:2016-01-21 00:00:00
abstract::Increased somatic mitochondrial DNA (mtDNA) mutagenesis causes premature aging in mice, and mtDNA damage accumulates in the human brain with aging and neurodegenerative disorders such as Parkinson disease (PD). Here, we study the complete spectrum of mtDNA changes, including deletions, copy-number variation and point ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13548
更新日期:2016-11-22 00:00:00
abstract::Host dependency factors that are required for influenza A virus infection may serve as therapeutic targets as the virus is less likely to bypass them under drug-mediated selection pressure. Previous attempts to identify host factors have produced largely divergent results, with few overlapping hits across different st...
journal_title:Nature communications
pub_type: 杂志文章,meta分析
doi:10.1038/s41467-019-13965-x
更新日期:2020-01-09 00:00:00
abstract::Hepatitis B virus (HBV) can integrate into the human genome, contributing to genomic instability and hepatocarcinogenesis. Here by conducting high-throughput viral integration detection and RNA sequencing, we identify 4,225 HBV integration events in tumour and adjacent non-tumour samples from 426 patients with HCC. We...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12992
更新日期:2016-10-05 00:00:00
abstract::Successive cold winters of severely low temperatures in recent years have had critical social and economic impacts on the mid-latitude continents in the Northern Hemisphere. Although these cold winters are thought to be partly driven by dramatic losses of Arctic sea-ice, the mechanism that links sea-ice loss to cold w...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5646
更新日期:2014-09-02 00:00:00
abstract::Ubiquitin-like (Ubl) modifications regulate nearly all cellular functions in eukaryotes with the largest superfamily of Ubl-specific proteases being Cys proteases. SENP1 is a model for this protease family and responsible for processing SUMO. Here using nuclear magnetic resonance relaxation measurements, chemical shif...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5968
更新日期:2014-09-29 00:00:00