Fossil black smoker yields oxygen isotopic composition of Neoproterozoic seawater.

abstract：:Everyone experiences common events differently. This leads to personal memories that presumably provide neural signatures of individual identity when events are reimagined. We present initial evidence that these signatures can be read from brain activity. To do this, we progress beyond previous work that has deployed ...

journal_title：Nature communications

authors： Anderson AJ,McDermott K,Rooks B,Heffner KL,Dodell-Feder D,Lin FV

更新日期：2020-11-20 00:00:00

abstract：:From intracellular protein trafficking to large-scale motion of animal groups, the physical concepts driving the self-organization of living systems are still largely unraveled. Self-organization of active entities, leading to novel phases and emergent macroscopic properties, recently shed new light on these complex d...

journal_title：Nature communications

authors： Vincenti B,Ramos G,Cordero ML,Douarche C,Soto R,Clement E

更新日期：2019-11-08 00:00:00

abstract：:Cas9/gRNA-mediated gene-drive systems have advanced development of genetic technologies for controlling vector-borne pathogen transmission. These technologies include population suppression approaches, genetic analogs of insecticidal techniques that reduce the number of insect vectors, and population modification (rep...

journal_title：Nature communications

authors： Adolfi A,Gantz VM,Jasinskiene N,Lee HF,Hwang K,Terradas G,Bulger EA,Ramaiah A,Bennett JB,Emerson JJ,Marshall JM,Bier E,James AA

更新日期：2020-11-03 00:00:00

abstract：:Large single-crystal graphene is highly desired and important for the applications of graphene in electronics, as grain boundaries between graphene grains markedly degrade its quality and properties. Here we report the growth of millimetre-sized hexagonal single-crystal graphene and graphene films joined from such gra...

journal_title：Nature communications

authors： Gao L,Ren W,Xu H,Jin L,Wang Z,Ma T,Ma LP,Zhang Z,Fu Q,Peng LM,Bao X,Cheng HM

更新日期：2012-02-28 00:00:00

abstract：:WNTs are lipid-modified proteins that control multiple functions in development and disease via short- and long-range signaling. However, it is unclear how these hydrophobic molecules spread over long distances in the mammalian brain. Here we show that WNT5A is produced by the choroid plexus (ChP) of the developing hi...

journal_title：Nature communications

authors： Kaiser K,Gyllborg D,Procházka J,Salašová A,Kompaníková P,Molina FL,Laguna-Goya R,Radaszkiewicz T,Harnoš J,Procházková M,Potěšil D,Barker RA,Casado ÁG,Zdráhal Z,Sedláček R,Arenas E,Villaescusa JC,Bryja V

更新日期：2019-04-02 00:00:00

abstract：:In fragmented forests, tree diversity declines near edges but the ecological processes underlying this loss of diversity remain poorly understood. Theory predicts that top-down regulation of seedling recruitment by insect herbivores and fungal pathogens contributes to maintaining tree diversity in forests, but it is u...

journal_title：Nature communications

authors： Krishnadas M,Bagchi R,Sridhara S,Comita LS

更新日期：2018-10-30 00:00:00

abstract：:Oxygen contamination is a problem which inevitably occurs during severe plastic deformation of metallic powders by exposure to air. Although this contamination can change the morphology and properties of the consolidated materials, there is a lack of detailed information about the behavior of oxygen in nanocrystalline...

journal_title：Nature communications

authors： Guo J,Haberfehlner G,Rosalie J,Li L,Duarte MJ,Kothleitner G,Dehm G,He Y,Pippan R,Zhang Z

更新日期：2018-03-05 00:00:00

abstract：:During meiosis, homologous chromosomes synapse and recombine at sites marked by the binding of the mismatch repair protein MLH1. In hexaploid wheat, the Ph1 locus has a major effect on whether crossover occurs between homologues or between related homoeologues. Here we report that--in wheat-rye hybrids where homologue...

journal_title：Nature communications

authors： Martín AC,Shaw P,Phillips D,Reader S,Moore G

更新日期：2014-08-06 00:00:00

abstract：:The miR-200 family members have been implicated in stress responses and ovarian tumorigenesis. Here, we find that miR-200c/141 transcription is intimately linked to the transcription of the proximal upstream gene PTPN6 (SHP1) in all physiological conditions tested. PTPN6 and miR-200c/141 are transcriptionally co-regul...

journal_title：Nature communications

authors： Batista L,Bourachot B,Mateescu B,Reyal F,Mechta-Grigoriou F

更新日期：2016-01-04 00:00:00

abstract：:Chirality is an intriguing property of certain molecules, materials or artificial nanostructures, which allows them to interact with the spin angular momentum of the impinging light field. Due to their chiral geometry, they can distinguish between left- and right-hand circular polarization states or convert them into ...

journal_title：Nature communications

authors： Banzer P,Woźniak P,Mick U,De Leon I,Boyd RW

更新日期：2016-10-13 00:00:00

abstract：:Self-assembly of proteins and inorganic nanoparticles into terminal assemblies makes possible a large family of uniformly sized hybrid colloids. These particles can be compared in terms of utility, versatility and multifunctionality to other known types of terminal assemblies. They are simple to make and offer theoret...

journal_title：Nature communications

authors： Park JI,Nguyen TD,de Queirós Silveira G,Bahng JH,Srivastava S,Zhao G,Sun K,Zhang P,Glotzer SC,Kotov NA

更新日期：2014-05-20 00:00:00

abstract：:State-of-the-art techniques allow researchers to record large numbers of spike trains in parallel for many hours. With enough such data, we should be able to infer the connectivity among neurons. Here we develop a method for reconstructing neuronal circuitry by applying a generalized linear model (GLM) to spike cross-...

journal_title：Nature communications

authors： Kobayashi R,Kurita S,Kurth A,Kitano K,Mizuseki K,Diesmann M,Richmond BJ,Shinomoto S

更新日期：2019-10-02 00:00:00

abstract：:The presence of a di-unsaturated highly branched isoprenoid (HBI) lipid biomarker (diene II) in Southern Ocean sediments has previously been proposed as a proxy measure of palaeo Antarctic sea ice. Here we show that a source of diene II is the sympagic diatom Berkeleya adeliensis Medlin. Furthermore, the propensity fo...

journal_title：Nature communications

authors： Belt ST,Smik L,Brown TA,Kim JH,Rowland SJ,Allen CS,Gal JK,Shin KH,Lee JI,Taylor KW

更新日期：2016-08-30 00:00:00

abstract：:The outcome of molecule-surface collisions can be modified by pre-aligning the molecule; however, experiments accomplishing this are rare because of the difficulty of preparing molecules in aligned quantum states. Here we present a general solution to this problem based on magnetic manipulation of the rotational magne...

journal_title：Nature communications

authors： Godsi O,Corem G,Alkoby Y,Cantin JT,Krems RV,Somers MF,Meyer J,Kroes GJ,Maniv T,Alexandrowicz G

更新日期：2017-05-08 00:00:00

abstract：:Mammalian female meiosis is error prone, with rates of meiotic chromosome missegregations strongly increasing towards the end of the reproductive lifespan. A strong reduction of BubR1 has been observed in oocytes of women approaching menopause and in ovaries of aged mice, which led to the hypothesis that a gradual dec...

journal_title：Nature communications

authors： Touati SA,Buffin E,Cladière D,Hached K,Rachez C,van Deursen JM,Wassmann K

更新日期：2015-04-21 00:00:00

abstract：:To balance immunity and tolerance, the endogenous pool of Foxp3+ regulatory T (Treg) cells is tightly controlled, but the underlying mechanisms of this control remain poorly understood. Here we show that the number of Treg cells is negatively regulated by the kinase Lkb1 in dendritic cells (DCs). Conditional knockout ...

journal_title：Nature communications

authors： Chen S,Fang L,Guo W,Zhou Y,Yu G,Li W,Dong K,Liu J,Luo Y,Wang B,Li Z,Zhao C,Sun Z,Shen Y,Leng Q,Zhou D,Han Z,Huang H,Ren H,Xu G,Feng X

更新日期：2018-12-13 00:00:00

abstract：:CD1 proteins are expressed on dendritic cells, where they display lipid antigens to T-cell receptors (TCRs). Here we describe T-cell autoreactivity towards ubiquitous human membrane phospholipids presented by CD1b. These T-cells discriminate between two major types of lipids, sphingolipids and phospholipids, but were ...

journal_title：Nature communications

authors： Shahine A,Reinink P,Reijneveld JF,Gras S,Holzheimer M,Cheng TY,Minnaard AJ,Altman JD,Lenz S,Prandi J,Kubler-Kielb J,Moody DB,Rossjohn J,Van Rhijn I

更新日期：2019-01-04 00:00:00

abstract：:The study of multicellular development is grounded in two complementary domains: cell biomechanics, which examines how physical forces shape the embryo, and genetic regulation and molecular signalling, which concern how cells determine their states and behaviours. Integrating both sides into a unified framework is cru...

journal_title：Nature communications

authors： Delile J,Herrmann M,Peyriéras N,Doursat R

更新日期：2017-01-23 00:00:00

abstract：:Non-pial neocortical astrocytes have historically been thought to comprise largely a nondiverse population of protoplasmic astrocytes. Here we show that astrocytes of the mouse somatosensory cortex manifest layer-specific morphological and molecular differences. Two- and three-dimensional observations revealed that as...

journal_title：Nature communications

authors： Lanjakornsiripan D,Pior BJ,Kawaguchi D,Furutachi S,Tahara T,Katsuyama Y,Suzuki Y,Fukazawa Y,Gotoh Y

更新日期：2018-04-24 00:00:00

abstract：:The unusual electronic properties of diamondoids, the nanoscale relatives of diamond, make them attractive for applications ranging from drug delivery to field emission displays. Identifying the fundamental origin of these properties has proven highly challenging, with even the most advanced quantum many-body calculat...

journal_title：Nature communications

authors： Patrick CE,Giustino F

更新日期：2013-01-01 00:00:00

abstract：:Piezo proteins are transmembrane ion channels which transduce many forms of mechanical stimuli into electrochemical signals. Their pore, formed by the assembly of three identical subunits, opens by an unknown mechanism. Here, to probe this mechanism, we investigate the interaction of Piezo1 with the small molecule ago...

journal_title：Nature communications

authors： Lacroix JJ,Botello-Smith WM,Luo Y

更新日期：2018-05-23 00:00:00

abstract：:Cleavage of transfer (t)RNA and ribosomal (r)RNA are critical and conserved steps of translational control for cells to overcome varied environmental stresses. However, enzymes that are responsible for this event have not been fully identified in high eukaryotes. Here, we report a mammalian tRNA/rRNA-targeting endorib...

journal_title：Nature communications

authors： Yang JY,Deng XY,Li YS,Ma XC,Feng JX,Yu B,Chen Y,Luo YL,Wang X,Chen ML,Fang ZX,Zheng FX,Li YP,Zhong Q,Kang TB,Song LB,Xu RH,Zeng MS,Chen W,Zhang H,Xie W,Gao S

更新日期：2018-03-21 00:00:00

abstract：:Adaptive behavior requires integrating prior with current information to anticipate upcoming events. Brain structures related to this computation should bring relevant signals from the recent past into the present. Here we report that rats can integrate the most recent prior information with sensory information, there...

journal_title：Nature communications

authors： Nogueira R,Abolafia JM,Drugowitsch J,Balaguer-Ballester E,Sanchez-Vives MV,Moreno-Bote R

更新日期：2017-03-24 00:00:00

abstract：:Eukaryotic cyclic nucleotide-modulated (CNM) ion channels perform various physiological roles by opening in response to cyclic nucleotides binding to a specialized cyclic nucleotide-binding domain. Despite progress in structure-function analysis, the conformational rearrangements underlying the gating of these channel...

journal_title：Nature communications

authors： Rangl M,Miyagi A,Kowal J,Stahlberg H,Nimigean CM,Scheuring S

更新日期：2016-09-20 00:00:00

abstract：:Valosin-containing protein (VCP, also called p97) is an essential and highly conserved adenosine triphosphate-dependent chaperone implicated in a wide range of cellular processes in eukaryotes, and mild VCP mutations can cause severe neurodegenerative disease. Here we show that mammalian VCP is trimethylated on Lys315...

journal_title：Nature communications

authors： Kernstock S,Davydova E,Jakobsson M,Moen A,Pettersen S,Mælandsmo GM,Egge-Jacobsen W,Falnes PØ

更新日期：2012-01-01 00:00:00

abstract：:Deep learning algorithms have been successfully used in medical image classification. In the next stage, the technology of acquiring explainable knowledge from medical images is highly desired. Here we show that deep learning algorithm enables automated acquisition of explainable features from diagnostic annotation-fr...

journal_title：Nature communications

authors： Yamamoto Y,Tsuzuki T,Akatsuka J,Ueki M,Morikawa H,Numata Y,Takahara T,Tsuyuki T,Tsutsumi K,Nakazawa R,Shimizu A,Maeda I,Tsuchiya S,Kanno H,Kondo Y,Fukumoto M,Tamiya G,Ueda N,Kimura G

更新日期：2019-12-18 00:00:00

abstract：:Considerable progress in the fabrication of quasicrystals demonstrates that they can be realized in a broad range of materials. However, the development of chemistries enabling direct experimental observation of early quasicrystal growth pathways remains challenging. Here, we report the synthesis of four surfactant-di...

journal_title：Nature communications

authors： Sun Y,Ma K,Kao T,Spoth KA,Sai H,Zhang D,Kourkoutis LF,Elser V,Wiesner U

更新日期：2017-08-15 00:00:00

abstract：:Quantifying chemical compositions around nanovoids is a fundamental task for research and development of various materials. Atom probe tomography (APT) and scanning transmission electron microscopy (STEM) are currently the most suitable tools because of their ability to probe materials at the nanoscale. Both technique...

journal_title：Nature communications

authors： Wang X,Hatzoglou C,Sneed B,Fan Z,Guo W,Jin K,Chen D,Bei H,Wang Y,Weber WJ,Zhang Y,Gault B,More KL,Vurpillot F,Poplawsky JD

更新日期：2020-02-24 00:00:00

abstract：:CD4(+) Th17 are heterogeneous in terms of cytokine production and capacity to initiate autoimmune diseases, such as experimental autoimmune encephalomyelitis (EAE). Here we demonstrate that experimental priming of encephalitogenic Th cells expressing RORγt and T-bet and producing IL-17A, IFN-γ and GM-CSF but not IL-10...

journal_title：Nature communications

authors： Ronchi F,Basso C,Preite S,Reboldi A,Baumjohann D,Perlini L,Lanzavecchia A,Sallusto F

更新日期：2016-05-18 00:00:00

abstract：:Forebrain neurons have weak intrinsic antioxidant defences compared with astrocytes, but the molecular basis and purpose of this is poorly understood. We show that early in mouse cortical neuronal development in vitro and in vivo, expression of the master-regulator of antioxidant genes, transcription factor NF-E2-rela...

journal_title：Nature communications

authors： Bell KF,Al-Mubarak B,Martel MA,McKay S,Wheelan N,Hasel P,Márkus NM,Baxter P,Deighton RF,Serio A,Bilican B,Chowdhry S,Meakin PJ,Ashford ML,Wyllie DJ,Scannevin RH,Chandran S,Hayes JD,Hardingham GE

更新日期：2015-05-13 00:00:00