Abstract:
:From intracellular protein trafficking to large-scale motion of animal groups, the physical concepts driving the self-organization of living systems are still largely unraveled. Self-organization of active entities, leading to novel phases and emergent macroscopic properties, recently shed new light on these complex dynamical processes. Here we show that under the application of a constant magnetic field, motile magnetotactic bacteria confined in water-in-oil droplets self-assemble into a rotary motor exerting a torque on the external oil phase. A collective motion in the form of a large-scale vortex, reversable by inverting the field direction, builds up in the droplet with a vorticity perpendicular to the magnetic field. We study this collective organization at different concentrations, magnetic fields and droplet radii and reveal the formation of two torque-generating areas close to the droplet interface. We characterize quantitatively the mechanical energy extractable from this new biological and self-assembled motor.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Vincenti B,Ramos G,Cordero ML,Douarche C,Soto R,Clement Edoi
10.1038/s41467-019-13031-6subject
Has Abstractpub_date
2019-11-08 00:00:00pages
5082issue
1issn
2041-1723pii
10.1038/s41467-019-13031-6journal_volume
10pub_type
杂志文章abstract::Energy affects every single individual and entity in the world. Therefore, it is crucial to precisely quantify the "price of energy" and study how it evolves through time, through major political and social events, and through changes in energy and monetary policies. Here, we develop a predictive framework, an index t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20203-2
更新日期:2021-01-04 00:00:00
abstract::Protein function and dynamics are closely related; however, accurate dynamics information is difficult to obtain. Here based on a carefully assembled data set derived from experimental data for proteins in solution, we quantify backbone dynamics properties on the amino-acid level and develop DynaMine--a fast, high-qua...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3741
更新日期:2013-01-01 00:00:00
abstract::Metal halide perovskites feature crystalline-like electronic band structures and liquid-like physical properties. The crystal-liquid duality enables optoelectronic devices with unprecedented performance and a unique opportunity to chemically manipulate the structure with low energy input. In this work, we leverage the...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19009-z
更新日期:2020-10-16 00:00:00
abstract::The mammary gland is a highly vascularized tissue capable of expansion and regression during development and disease. To enable mechanistic insight into the coordinated morphogenic crosstalk between the epithelium and vasculature, we introduce a 3D microfluidic platform that juxtaposes a human mammary duct in proximit...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17102-x
更新日期:2020-07-06 00:00:00
abstract::The functional role of adult neurogenesis in the hippocampus remains the subject of intense speculation. One recent hypothesis is that adult-born neurons contribute to the endocrine and behavioural outputs of the stress response. Here we show a genetic model system to ablate neurogenesis by inducibly deleting Tbr2 gen...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9373
更新日期:2015-09-29 00:00:00
abstract::Little is known about how our brains dynamically adapt for efficient functioning. Most previous work has focused on analyzing changes in co-fluctuations between a set of brain regions over several temporal segments of the data. We argue that by collapsing data in space or time, we stand to lose useful information abou...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03664-4
更新日期:2018-04-11 00:00:00
abstract::Large-scale genomic analyses of human cancers have cataloged somatic point mutations thought to initiate tumor development and sustain cancer growth. However, determining the functional significance of specific alterations remains a major bottleneck in our understanding of the genetic determinants of cancer. Here, we ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01519-y
更新日期:2017-12-12 00:00:00
abstract::Despite the increasing resolution, forcing on the mean circulation by resolved waves in general circulation models is not yet converging. Parameterization of the forcing remains a major source of model uncertainty. This study examines the scale invariance of zonal spectra of momentum flux and wave forcing, and shows t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10527-z
更新日期:2019-06-13 00:00:00
abstract::The phosphorylation of eIF4E1 at serine 209 by MNK1 or MNK2 has been shown to initiate oncogenic mRNA translation, a process that favours cancer development and maintenance. Here, we interrogate the MNK-eIF4E axis in diffuse large B-cell lymphoma (DLBCL) and show a distinct distribution of MNK1 and MNK2 in germinal ce...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6413
更新日期:2014-11-18 00:00:00
abstract::The caudal-related homeobox transcription factor CDX2 is expressed in leukemic cells but not during normal blood formation. Retroviral overexpression of Cdx2 induces AML in mice, however the developmental stage at which CDX2 exerts its effect is unknown. We developed a conditionally inducible Cdx2 mouse model to deter...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16840-2
更新日期:2020-06-15 00:00:00
abstract::Gas-sensing materials are becoming increasingly important in our society, requiring high sensitivity to differentiate similar gases like N2 and O2. For the design of such materials, the driving force of electronic host-guest interaction or host-framework changes during the sorption process has commonly been considered...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07889-1
更新日期:2018-12-21 00:00:00
abstract::As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different types of cancer, chronic lymphocytic leukaemia and medulloblastoma, we conduct a benchmarking e...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10001
更新日期:2015-12-09 00:00:00
abstract::Scaffolded DNA origami has proven to be a powerful and efficient technique to fabricate functional nanomachines by programming the folding of a single-stranded DNA template strand into three-dimensional (3D) nanostructures, designed to be precisely motion-controlled. Although two-dimensional (2D) imaging of DNA nanoma...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03018-0
更新日期:2018-02-09 00:00:00
abstract::Riboswitches are naturally occurring RNA aptamers that regulate gene expression by binding to specific small molecules. Riboswitches control the expression of essential bacterial genes and are important models for RNA-small molecule recognition. Here, we report the discovery of a class of synthetic small molecules tha...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09493-3
更新日期:2019-04-02 00:00:00
abstract::Inspired by biological neural systems, neuromorphic devices may open up new computing paradigms to explore cognition, learning and limits of parallel computation. Here we report the demonstration of a synaptic transistor with SmNiO₃, a correlated electron system with insulator-metal transition temperature at 130°C in ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3676
更新日期:2013-01-01 00:00:00
abstract::The potential of the folic acid biosynthesis pathway as a target for the development of antibiotics has been clinically validated. However, many pathogens have developed resistance to these antibiotics, prompting a re-evaluation of potential drug targets within the pathway. The ydaH gene of Alcanivorax borkumensis enc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7874
更新日期:2015-04-20 00:00:00
abstract::In the quantum Hall regime, near integer filling factors, electrons should only be transmitted through spatially separated edge states. However, in mesoscopic systems, electronic transmission turns out to be more complex, giving rise to a large spectrum of magnetoresistance oscillations. To explain these observations,...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1038
更新日期:2010-07-27 00:00:00
abstract::Neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and Huntington's disease manifest with the neuronal accumulation of toxic proteins. Since autophagy upregulation enhances the clearance of such proteins and ameliorates their toxicities in animal models, we and others have sought to re-position/r...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09494-2
更新日期:2019-04-18 00:00:00
abstract::5-Fluorouracil (5-FU) remains the first-line treatment for colorectal cancer (CRC). Although 5-FU initially de-bulks the tumor mass, recurrence after chemotherapy is the barrier to effective clinical outcomes for CRC patients. Here, we demonstrate that p53 promotes WNT3 transcription, leading to activation of the WNT/...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19173-2
更新日期:2020-10-21 00:00:00
abstract::Since the formulation of the geometric phase by Berry, its relevance has been demonstrated in a large variety of physical systems. However, a geometric phase of the most fundamental spin-1/2 system, the electron spin, has not been observed directly and controlled independently from dynamical phases. Here we report exp...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3526
更新日期:2013-01-01 00:00:00
abstract::Neuronal reward valuations provide the physiological basis for economic behaviour. Yet, how such valuations are converted to economic decisions remains unclear. Here we show that the dorsolateral prefrontal cortex (DLPFC) implements a flexible value code based on object-specific valuations by single neurons. As monkey...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12554
更新日期:2016-09-13 00:00:00
abstract::Elucidating the factors governing the functional compatibility of horizontally transferred genes is important to understand bacterial evolution, including the emergence and spread of antibiotic resistance, and to successfully engineer biological systems. In silico efforts and work using single-gene libraries have sugg...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-02944-3
更新日期:2018-02-06 00:00:00
abstract::Two-dimensional transition metal carbides (MXenes) have attracted a great interest of the research community as a relatively recently discovered large class of materials with unique electronic and optical properties. Understanding of adhesion between MXenes and various substrates is critically important for MXene devi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10982-8
更新日期:2019-07-08 00:00:00
abstract::Recently, stretchable electronics combined with wireless technology have been crucial for realizing efficient human-machine interaction. Here, we demonstrate highly stretchable transparent wireless electronics composed of Ag nanofibers coils and functional electronic components for power transfer and information commu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19367-8
更新日期:2020-11-06 00:00:00
abstract::Locusts are one of the world's most destructive agricultural pests and represent a useful model system in entomology. Here we present a draft 6.5 Gb genome sequence of Locusta migratoria, which is the largest animal genome sequenced so far. Our findings indicate that the large genome size of L. migratoria is likely to...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3957
更新日期:2014-01-01 00:00:00
abstract::Common fragile sites (CFSs) are chromosome regions prone to breakage upon replication stress known to drive chromosome rearrangements during oncogenesis. Most CFSs nest in large expressed genes, suggesting that transcription could elicit their instability; however, the underlying mechanisms remain elusive. Genome-wide...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13674-5
更新日期:2019-12-13 00:00:00
abstract::Plasma membrane Ca2+-ATPases (PMCAs) are key regulators of global Ca2+ homeostasis and local intracellular Ca2+ dynamics. Recently, Neuroplastin (NPTN) and basigin were identified as previously unrecognized obligatory subunits of PMCAs that dramatically increase the efficiency of PMCA-mediated Ca2+ clearance. Here, we...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06075-7
更新日期:2018-09-06 00:00:00
abstract::Land-atmosphere exchanges influence atmospheric CO2. Emphasis has been on describing photosynthetic CO2 uptake, but less on respiration losses. New global datasets describe upper canopy dark respiration (R d) and temperature dependencies. This allows characterisation of baseline R d, instantaneous temperature response...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01774-z
更新日期:2017-11-17 00:00:00
abstract::Understanding the response of granular matter to intrusion of solid objects is key to modelling many aspects of behaviour of granular matter, including plastic flow. Here we report a general model for such a quasistatic process. Using a range of experiments, we first show that the relation between the penetration dept...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03344-3
更新日期:2018-03-16 00:00:00
abstract::Phase separation of specific biomolecules into liquid droplet-like condensates is a key mechanism to form membrane-less organelles, which spatio-temporally organize diverse biochemical processes in cells. To investigate the working principles of these biomolecular condensates as dynamic reaction centers, precise contr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19391-8
更新日期:2020-11-03 00:00:00