Abstract:
:As children grow, they gradually learn how to make decisions independently. However, decisions like choosing healthy but less-tasty foods can be challenging for children whose self-regulation and executive cognitive functions are still maturing. We propose a computational decision-making process in which children estimate their mother's choices for them as well as their individual food preferences. By employing functional magnetic resonance imaging during real food choices, we find that the ventromedial prefrontal cortex (vmPFC) encodes children's own preferences and the left dorsolateral prefrontal cortex (dlPFC) encodes the projected mom's choices for them at the time of children's choice. Also, the left dlPFC region shows an inhibitory functional connectivity with the vmPFC at the time of children's own choice. Our study suggests that in part, children utilize their perceived caregiver's choices when making choices for themselves, which may serve as an external regulator of decision-making, leading to optimal healthy decisions.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Lim SL,Cherry JB,Davis AM,Balakrishnan SN,Ha OR,Bruce JM,Bruce ASdoi
10.1038/ncomms11700subject
Has Abstractpub_date
2016-05-24 00:00:00pages
11700issn
2041-1723pii
ncomms11700journal_volume
7pub_type
杂志文章abstract::Hallmarks of criticality, such as power-laws and scale invariance, have been empirically found in cortical-network dynamics and it has been conjectured that operating at criticality entails functional advantages, such as optimal computational capabilities, memory and large dynamical ranges. As critical behaviour requi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3521
更新日期:2013-01-01 00:00:00
abstract::Chemical synthesis of amino acids from renewable sources is an alternative route to the current processes based on fermentation. Here, we report visible-light-driven amination of biomass-derived α-hydroxyl acids and glucose into amino acids using NH3 at 50 °C. Ultrathin CdS nanosheets are identified as an efficient an...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18532-3
更新日期:2020-09-29 00:00:00
abstract::Human C-terminal binding protein (CtBP)-interacting protein (CtIP) is a central regulator to initiate DNA end resection and homologous recombination (HR). Several studies have shown that post-translational modifications control the activity or expression of CtIP. However, it remains unclear whether and how cells restr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19202-0
更新日期:2020-10-23 00:00:00
abstract::Netrins, a family of laminin-related molecules, have been proposed to act as guidance cues either during nervous system development or the establishment of the vascular system. This was clearly demonstrated for netrin-1 via its interaction with the receptors DCC and UNC5s. However, mainly based on shared homologies wi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13515
更新日期:2016-11-30 00:00:00
abstract::Due to the generally delocalized nature of molecular valence orbitals, valence-shell spectroscopies do not usually allow to specifically target a selected atom in a molecule. However, in X-ray electron spectroscopy, the photoelectron momentum is large and the recoil angular momentum transferred to the molecule is larg...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4816
更新日期:2014-05-09 00:00:00
abstract::Efficient and low-cost electrocatalysts for the oxygen evolution reaction are essential components of renewable energy technologies, such as solar fuel synthesis and providing a hydrogen source for powering fuel cells. Here we report that the nitrogen-doped carbon materials function as the efficient oxygen evolution e...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3390
更新日期:2013-01-01 00:00:00
abstract::CD1 proteins are expressed on dendritic cells, where they display lipid antigens to T-cell receptors (TCRs). Here we describe T-cell autoreactivity towards ubiquitous human membrane phospholipids presented by CD1b. These T-cells discriminate between two major types of lipids, sphingolipids and phospholipids, but were ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07898-0
更新日期:2019-01-04 00:00:00
abstract::Osteoderms are bones embedded within the dermis, and are common to select members of most major tetrapod lineages. The largest known animals that bear osteoderms are members of Titanosauria, a diverse clade of sauropod dinosaurs. Here we report on two titanosaur osteoderms recovered from the Upper Cretaceous Maevarano...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1578
更新日期:2011-11-29 00:00:00
abstract::In chronic lymphocytic leukemia (CLL), the non-hematopoietic stromal microenvironment plays a critical role in promoting tumor cell recruitment, activation, survival, and expansion. However, the nature of the stromal cells and molecular pathways involved remain largely unknown. Here, we demonstrate that leukemic B lym...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-04150-7
更新日期:2018-05-03 00:00:00
abstract::The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however, mechanisms of structural homeostasis remain poorly understood. Conflicting models propose that stereocilia F-actin cores are either continually renewed every 24-48 h via a treadmill or are stable, exceptionally long-lived struc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7873
更新日期:2015-04-21 00:00:00
abstract::Decision making in dynamic environments requires discounting old evidence that may no longer inform the current state of the world. Previous work found that humans discount old evidence in a dynamic environment, but do not discount at the optimal rate. Here we investigated whether rats can optimally discount evidence ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06561-y
更新日期:2018-10-15 00:00:00
abstract::SIRT1 is the most evolutionarily conserved mammalian sirtuin, and it plays a vital role in the regulation of metabolism, stress responses, genome stability, and ageing. As a stress sensor, SIRT1 deacetylase activity is significantly increased during stresses, but the molecular mechanisms are not yet fully clear. Here,...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01654-6
更新日期:2017-11-14 00:00:00
abstract::Most DNA in the genomes of higher organisms does not encode proteins, yet much is transcribed by RNA polymerase II (RNAPII) into long non-coding RNAs (lncRNAs). The biological significance of most lncRNAs is largely unclear. Here, we identify a lncRNA (SVALKA) in a cold-sensitive region of the Arabidopsis genome. Muta...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07010-6
更新日期:2018-11-01 00:00:00
abstract::Recent efforts to evaluate the contribution of neonicotinoid insecticides to worldwide pollinator declines have focused on honey bees and the chronic levels of exposure experienced when foraging on crops grown from neonicotinoid-treated seeds. However, few studies address non-crop plants as a potential route of pollin...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11629
更新日期:2016-05-31 00:00:00
abstract::The high incidence of aneuploidy in the embryo is considered the principal cause for low human fecundity. However, the prevalence of aneuploidy dramatically declines as pregnancy progresses, with the steepest drop occurring as the embryo completes implantation. Despite the fact that the plasticity of the embryo in dea...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16796-3
更新日期:2020-06-11 00:00:00
abstract::The brain identifies potentially salient features within continuous information streams to process hierarchical temporal events. This requires the compression of information streams, for which effective computational principles are yet to be explored. Backpropagating action potentials can induce synaptic plasticity in...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15367-w
更新日期:2020-03-25 00:00:00
abstract::The precise measurement of forces is one way to obtain deep insight into the fundamental interactions present in nature. In the context of neutral antimatter, the gravitational interaction is of high interest, potentially revealing new forces that violate the weak equivalence principle. Here we report on a successful ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5538
更新日期:2014-07-28 00:00:00
abstract::The need for active and stable oxidation catalysts is driven by the demands in production of valuable chemicals, remediation of hydrocarbon pollutants and energy sustainability. Traditional approaches focus on oxygen-activating oxides as support which provides the oxygen activation at the catalyst-support peripheral i...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18017-3
更新日期:2020-08-21 00:00:00
abstract::Fusion proteins containing blue-light-activable protein domains possess great potential as molecular switches in cell signalling. This has recently been impressively demonstrated by connecting the light oxygen voltage LOV2-Jα-protein domain of A. sativa (AsLOV2-Jα) with the Rac1-GTPase, responsible for regulating the ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1121
更新日期:2010-11-16 00:00:00
abstract::All motile organisms use spatially distributed chemical features of their surroundings to guide their behaviors, but the neural mechanisms underlying such behaviors in mammals have been difficult to study, largely due to the technical challenges of controlling chemical concentrations in space and time during behaviora...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03262-4
更新日期:2018-02-26 00:00:00
abstract::Exosomes are nanometer-sized lipid vesicles present in liquid biopsies and used as biomarkers for several diseases including cancer, Alzheimer's, and central nervous system diseases. Purification and subsequent size and surface characterization are essential to exosome-based diagnostics. Sample purification is, howeve...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15889-3
更新日期:2020-05-11 00:00:00
abstract::Macrophages play a pivotal role in tissue fibrogenesis, which underlies the pathogenesis of many end-stage chronic inflammatory diseases. MicroRNAs are key regulators of immune cell functions, but their roles in macrophage's fibrogenesis have not been characterized. Here we show that IL-4 and IL-13 induce miR-142-5p a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9523
更新日期:2015-10-05 00:00:00
abstract::Rotational invariance strongly constrains the viscosity tensor of classical fluids. When this symmetry is broken in anisotropic materials a wide array of novel phenomena become possible. We explore electron fluid behaviors arising from the most general viscosity tensors in two and three dimensions, constrained only th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18553-y
更新日期:2020-09-18 00:00:00
abstract::The restricted availability, expense and toxicity of precious metal catalysts such as rhodium and palladium challenge the sustainability of synthetic chemistry. As such, nickel catalysts have garnered increasing attention as replacements for enyne cyclization reactions. On the other hand, bridged tricyclo[5.2.1.01,5]d...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15837-1
更新日期:2020-04-20 00:00:00
abstract::In the original version of this Article, the affiliation details for Antoine Aze, Michalis Fragkos, Stéphane Bocquet, Julien Cau and Marcel Méchali incorrectly omitted 'CNRS and the University of Montpellier'. This has now been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-02968-9
更新日期:2018-02-05 00:00:00
abstract::Blood brain barrier (BBB) breakdown is not only a consequence of but also contributes to many neurological disorders, including stroke and Alzheimer's disease. How the basement membrane (BM) contributes to the normal functioning of the BBB remains elusive. Here we use conditional knockout mice and an acute adenovirus-...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4413
更新日期:2014-03-03 00:00:00
abstract::The modern energy economy and environmental infrastructure rely on the flow of fluids through fractures in rock. Yet this flow cannot be imaged directly because rocks are opaque to most probes. Here we apply chattering dust, or chemically reactive grains of sucrose containing pockets of pressurized carbon dioxide, to ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19087-z
更新日期:2020-10-19 00:00:00
abstract::Increased lipogenesis has been linked to an increased cancer risk and poor prognosis; however, the underlying mechanisms remain obscure. Here we show that phosphatidic acid phosphatase (PAP) lipin-1, which generates diglyceride precursors necessary for the synthesis of glycerolipids, interacts with and is a direct sub...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19694-w
更新日期:2020-11-17 00:00:00
abstract::The original version of this Article contained errors in Figs. 1a, 2a, 3a, and 4b, in which the units on the scale bars incorrectly read 'µm' rather than the correct 'nm.' This has been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-03634-w
更新日期:2018-03-14 00:00:00
abstract::Development of efficient catalysts for selective electroreduction of CO2 to high-value products is essential for the deployment of carbon utilization technologies. Here we present a scalable method for preparing Cu electrocatalysts that favor CO2 conversion to C2+ products with faradaic efficiencies up to 72%. Grazing...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16998-9
更新日期:2020-07-17 00:00:00