End of life experiences of patients with advanced cancer in Myanmar: Results from the APPROACH study.

abstract：AIM:Self-expandable metallic stents (SEMS) have been used for palliation in patients with malignant gastroduodenal obstructions. We evaluated clinical outcomes after SEMS placement and identified prognostic factors of SEMS patency, including chemotherapy. METHODS:A review of records of 85 patients with unresectable ga...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cha BH,Lee SH,Kim JE,Yoo JY,Park YS,Kim JW,Jeong SH,Kim N,Lee DH,Hwang JH

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Docetaxel is an effective therapy for metastatic castration-resistant prostate cancer (mCRPC); however, many patients experience febrile neutropenia (FN) and cease treatment early due to toxicity. It is not known whether lower dose (LD) q3-weekly docetaxel impacts toxicity or efficacy. METHODS:Multicenter r...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hamid AA,Willson K,Vincent AD,Tamjid B,Lee M,Bergin A,Gan C,Campbell A,Stewart J,Pezaro C,Tran B,Weickhardt AJ

更新日期：2018-10-01 00:00:00

abstract：AIMS:Quality of life (QOL) is important in patients with advanced cancer. The European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 is a general QOL tool used in cancer patients. Often, with a large enough sample, statistical significance of changecan be reached, however the clinical significance i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Bedard G,Zeng L,Zhang L,Lauzon N,Holden L,Tsao M,Danjoux C,Barnes E,Sahgal A,Poon M,Chow E

更新日期：2014-06-01 00:00:00

abstract：AIM:Colorectal cancer (CRC) is one of the most common malignancies worldwide and adjuvant chemotherapy is proven to improve survival in patients with Dukes' C CRC. The purpose of this study was to analyze factors influencing referral to medical oncology in patients with Dukes' C colonic cancer in our institutions. MET...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lu CT,Stephens JH,Rieger NA

更新日期：2010-09-01 00:00:00

abstract：AIM:The aim of this study was to explore the dynamics within second medical opinion consultations in patients with cancer. METHODS:Semi-structured interviews were held with four oncologists and were subjected to a thematic analysis to define the broad issues. These formed the basis of a survey distributed to Australia...

journal_title：Asia-Pacific journal of clinical oncology

authors： Philip J,Gold M,Schwarz M,Komesaroff P

更新日期：2011-03-01 00:00:00

abstract：AIM:A newly developed cervical cancer screening method - folate receptor-mediated epithelium staining utilizes methylene blue internalized by folate receptor-mediated endocytosis to stain cervical intra-epithelial neoplasia. We test the clinical feasibility of this method in this study. METHODS:A total of 14 344 women...

journal_title：Asia-Pacific journal of clinical oncology

authors： Li D,Chen L,Wang H,Yang H,Dai Y,Yu C,Dong Y

更新日期：2017-02-01 00:00:00

abstract：AIM:This study examined pathological quality-of-surgery indicators in laparoscopic and open rectal cancer resection specimens. METHODS:Retrospective analysis of consecutive, prospectively recorded laparoscopic (LR) or open (OR) resections for rectal cancer. Indicators included integrity of the perirectal fascial envel...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cheung HYC,Dent OF,Richardson GL,Chan C,Keshava A,Young CJ

更新日期：2018-04-01 00:00:00

abstract：AIM:To investigate the role of endothelial cell damage in radiation-induced lung injury. METHODS:A total of 60 male Sprague-Dawley rats were irradiated to the right hemithorax with a single dose of 0, 7.0 or 14.4 Gy. Serial studies were performed before and at 1, 7, 30 and 90 days after radiation, respectively. Pathol...

journal_title：Asia-Pacific journal of clinical oncology

authors： Qiu J,Li J,He TC

更新日期：2011-12-01 00:00:00

abstract：:The association between the rs498872 single nucleotide polymorphism (SNP) and glioma risk has been studied, but these studies have yielded conflicting results. In order to explore this association, we performed a meta-analysis. A comprehensive literature search was performed using PubMed and EMBASE database, with the ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Gao X,Mi Y,Yan A,Sha B,Guo N,Hu Z,Zhang N,Jiang F,Gou X

更新日期：2015-12-01 00:00:00

abstract：AIMS:The Australian Institute of Health and Welfare (AIHW) is a major national agency established by the Australian government to provide information and statistics on Australia's health and welfare. The AIHW and the Australasian Association of Cancer Registries collaborate every year to provide updated information on ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Australian Institute of Health and Welfare.

更新日期：2013-09-01 00:00:00

abstract：AIM:A viable and sustainable medical oncology profession is integral for meeting the increasing demand for quality cancer care. The aim of this study was to explore the workforce-related experiences, perceptions and career expectations of early-career medical oncologists in Australia. METHODS:A mixed-methods design, i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wong WKT,Kirby E,Broom A,Sibbritt D,Francis K,Karapetis CS,Karikios D,Harrup R,Lwin Z

更新日期：2018-10-01 00:00:00

abstract：AIM:Clinical and pharmacokinetic effects of azacitidine in higher-risk myelodysplastic syndromes were established in mainly Caucasian populations. Because of inter-ethnic genotype variability of drug-metabolizing enzymes, it is important to evaluate azacitidine in populations expected to use the drug. METHODS:In this ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chou WC,Yeh SP,Hsiao LT,Lin SF,Chen YC,Chen TY,Laille E,Galettis A,Dong Q,Songer S,Beach CL

更新日期：2017-10-01 00:00:00

abstract：:Non-small cell lung cancers (NSCLC) harboring the uncommon epidermal growth factor receptor (EGFR) exon 20 insertion mutations are generally thought to be unresponsive to EGFR-tyrosine kinase inhibitor (TKI) therapy. Presented here is a case of stage IV NSCLC harboring an uncommon EGFR exon 20 insertion mutation that ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chan RT

更新日期：2018-03-01 00:00:00

abstract：AIM:We aimed to analyze surgical outcomes of open or laparoscopic adrenalectomy for solitary adrenal metastasis and assess the factors influencing survival. METHODS:We retrospectively reviewed our institutional clinicopathological database for cases of adrenalectomy for solitary adrenal metastasis from solid tumors be...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hatano K,Horii S,Nakai Y,Nakayama M,Kakimoto KI,Nishimura K

更新日期：2020-04-01 00:00:00

abstract：AIM:Selective internal radiation therapy with yttrium-90 microsphere radioembolization has been used to treat unresectable liver tumors and its acute toxicity has been well described. Subacute and long-term hepatic complications related to radioembolization however may be underreported in the literature. This retrospec...

journal_title：Asia-Pacific journal of clinical oncology

authors： Kuo JC,Tazbirkova A,Allen R,Kosmider S,Gibbs P,Yip D

更新日期：2014-09-01 00:00:00

abstract：:Ipilimumab is a human anti-CTLA-4 monoclonal antibody recently approved for the treatment of advanced melanoma. Stimulation of T-cell activity unmasks antitumor activity, but can cause immune-related adverse events. Autoimmune hypophysitis is of particular importance because its presentation can be subtle but life thr...

journal_title：Asia-Pacific journal of clinical oncology

authors： Tiu C,Pezaro C,Davis ID,Grossmann M,Parente P

更新日期：2015-06-01 00:00:00

abstract：:The precise cell types that give rise to tumors and mechanisms that underpin tumor heterogeneity are poorly understood. There is increasing evidence to suggest that diverse solid tumors are hierarchically organized and may be sustained by a distinct subpopulation of cancer stem cells (CSCs). The CSC hypothesis provide...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lindeman GJ,Visvader JE

更新日期：2010-06-01 00:00:00

abstract：:We report a case of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) that developed in a patient with cholangiocarcinoma after receiving oxaliplatin-based chemotherapy. A 62-year-old man had multiple hypodense lesions with delayed enhancement in the both lobes of the liver on abdominal computed tomograph...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yoon JY,Nam TS,Kim MK,Hwang JE,Shim HJ,Cho SH,Chung IJ,Bae WK

更新日期：2012-06-01 00:00:00

abstract：AIM:Gastric cancer patients are normally treated with oral fluoropyrimidine and cisplatin or oxaliplatin; however, treating patients who also have a gastrointestinal obstruction is often difficult because of their poor oral intake. Instead, a modified (m)FOLFOX-6 regimen is administered, even to patients with gastroint...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yukami H,Terazawa T,Goto M,Aoki M,Asaishi K,Yamaguchi T,Kuwakado S,Kii T,Higuchi K

更新日期：2019-10-01 00:00:00

abstract：AIM:Important factors typically associated with prognosis in brain metastases include Karnofsky performance status (KPS), extracranial or cerebellar localization and combination chemotherapy. However, few studies investigated the prognostic role of leptomeningeal metastases (LM) following whole brain radiotherapy (WBRT...

journal_title：Asia-Pacific journal of clinical oncology

authors： Sakaguchi M,Maebayashi T,Aizawa T,Ishibashi N,Saito T

更新日期：2017-10-01 00:00:00

abstract：AIM:For several decades urinary arylsulfatase (ARS) activity has been reported to be elevated in many cancers. It has been shown that urinary ARS activity may serve as a marker of tumor progression and therapy surveillance. This study was designed to evaluate the clinical application of detection of urinary ARS activit...

journal_title：Asia-Pacific journal of clinical oncology

authors： Niu R,Jing H,Chen Z,Xu J,Dai J,Yan Z

更新日期：2012-12-01 00:00:00

abstract：AIM:The effects of image-guided radiotherapy (IGRT, an advanced RT technology) have been debated in the literature. We compared the outcomes of locally advanced rectal cancer (LARC) patients treated with neoadjuvant concurrent chemoradiotherapy (NCCRT; with vs without IGRT) in a large population-based propensity score ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Li CC,Liang JA,Chen WT,Chien CR

更新日期：2019-10-01 00:00:00

abstract：:The COVID-19 pandemic will present a range of challenges to radiation oncology departments. Early data suggest that cancer patients carry a higher than average, but still low absolute risk of hospitalization from COVID-19. The risk of severe events for those who are hospitalized however, is high. Resources for usual c...

journal_title：Asia-Pacific journal of clinical oncology

authors： Horsley PJ,Back M,Lamoury G,Porter B,Booth J,Eade TN

更新日期：2021-02-01 00:00:00

abstract：AIM:Complementary medicine (CAM) use in the cancer population is higher than the general population: some studies estimate up to 70%. Our Medicines Information Centre, in a tertiary cancer institution, receives many enquiries regarding use and safety of CAM with conventional cancer therapies (chemotherapy, radiotherapy...

journal_title：Asia-Pacific journal of clinical oncology

authors： Brooks SL,Rowan G,Michael M

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:An elevated preoperative aspartate aminotransferase-to-lymphocyte ratio index (ALRI) may predict poor survival in various cancers. However, the prognostic value of aminotransferase-to-lymphocyte ratio index (ALRI) in patients with hepatocellular carcinoma (HCC) remains to be determined. MATERIALS AND METHOD...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen Y,He C,Wen T,Yan L,Yang J

更新日期：2020-10-30 00:00:00

abstract：BACKGROUND:Clinical trials investigating the effects of addition of oxaliplatin to neoadjuvant radiochemotherapy in locally advanced rectal cancers (LARCs) have brought controversial results for pathologic complete response as an endpoint. This randomized clinical trial investigated downstaging as a short-term surrogat...

journal_title：Asia-Pacific journal of clinical oncology

authors： Haddad P,Miraie M,Farhan F,Fazeli MS,Alikhassi A,Maddah-Safaei A,Aghili M,Kalaghchi B,Babaei M

更新日期：2017-12-01 00:00:00

abstract：AIM:The objective of this economic evaluation, which was based on patients from two randomized controlled clinical trials (NO16966 and NO16967), was to compare direct medical costs to the Australian health-care system of capecitabine plus oxaliplatin (XELOX) and bolus and/or infusional 5-fluorouracil (5-FU) plus folini...

journal_title：Asia-Pacific journal of clinical oncology

authors： Tran G,Hack SP,Kerr A,Stokes L,Gibbs P,Price T,Todd C

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Metastatic colorectal cancer (mCRC) patients with a right-sided primary (RC) have an inferior survival to mCRC arising from a left-sided primary (LC). Previous analyses have suggested multiple factors contribute. METHODS:The Treatment of Recurrent and Advanced Colorectal Cancer (TRACC) Registry prospectivel...

journal_title：Asia-Pacific journal of clinical oncology

authors： Mendis S,Beck S,Lee B,Lee M,Wong R,Kosmider S,Shapiro J,Yip D,Steel S,Nott L,Jennens R,Lipton L,Burge M,Field K,Ananda S,Wong HL,Gibbs P

更新日期：2019-06-01 00:00:00

abstract：AIM:This systematic review and meta-analysis was performed to assess the efficacy and side effects between single-agent and doublet chemotherapy in first-line treatment of advanced non-small cell lung cancer with performance status 2 (PS2). METHODS:We searched for randomized controlled trials in online electronic data...

journal_title：Asia-Pacific journal of clinical oncology

authors： Luo L,Hu Q,Jiang JX,Yang X,Dinglin XX,Lin X,Yao HR

更新日期：2015-09-01 00:00:00

abstract：AIM:For early-stage breast cancer, four cycles of docetaxel and cyclophosphamide (TC) was proven superior to doxorubicin plus cyclophosphamide in the US Oncology 9375 trial. Given primary prophylactic antibiotics, 5% febrile neutropenia was recorded in a population comprising 75.5% Caucasians. Smaller trials and retros...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chow LWC,Biganzoli L,Leo AD,Kuroi K,Han HS,Patel J,Huang CS,Lu YS,Zhu L,Chow CYC,Loo WTY,Glück S,Toi M

更新日期：2017-12-01 00:00:00