Syphilitic Pulmonary Inflammatory Pseudotumor: A Diagnostic Challenge.

Abstract:

:A 46-year-old man presented with nonproductive cough and lower limb swelling. Chest radiograph showed a left lower lobe lung mass and multiple subpleural nodules. Other investigations revealed that he had nephrotic syndrome. Core biopsies of the left lower lobe lung mass showed features of inflammatory pseudotumor with endarteritis obliterans and a lymphoplasmacytic infiltrate. Immunohistochemical stain for Treponema pallidum was positive. Resolution of the lung mass and nephrotic syndrome was achieved after treatment with intramuscular benzathine benzylpenicillin. The differential diagnosis of pulmonary inflammatory pseudotumor, manifestations of pulmonary syphilis, and a literature review of secondary syphilis of the lung are discussed.

journal_name

Int J Surg Pathol

authors

Govender D,Jackson C,Chetty D

doi

10.1177/1066896920928584

subject

Has Abstract

pub_date

2021-02-01 00:00:00

pages

90-96

issue

1

eissn

1066-8969

issn

1940-2465

journal_volume

29

pub_type

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