Abstract:
Purpose:To evaluate the difference in the repeatability of automated superficial retinal vessel density and foveal avascular zone (FAZ) metrics according to the measurement area of optical coherence tomography angiography (OCTA). Methods:A total of 127 normal eyes from 127 healthy subjects were included. Macular angiography images were acquired from all subjects using the Zeiss Cirrus 5000 with AngioPlex™ OCTA software. Scans of 3 × 3 mm and 6 × 6 mm were each performed twice in a randomly arranged sequence. Vessel density (VD), perfusion density (PD), and FAZ metrics of the superficial capillary plexus were calculated automatically for all scans, and the repeatabilities for both scan patterns were assessed based on intraclass correlation (ICC), coefficient of variation (CV), and coefficient of repeatability (CR) parameters. The average measured values in the two scan patterns were also compared. Results:VD was significantly greater in the 3 × 3 mm scan than in the 6 × 6 mm scan according to all parameters, whereas PD was significantly less in the 3 × 3 mm scan than in the 6 × 6 mm scan. The ICCs for VDs in the central fovea were 0.826 and 0.741 for the 3 × 3 and 6 × 6 mm scans, respectively, and the CVs were 8.00% and 12.75%. For PDs, the ICCs were 0.839 and 0.762 and the CVs were 9.32% and 14.90%. The FAZ metrics in the 3 × 3 mm scan showed good repeatability with an ICC >0.75 and a CV <10.0%. However, all ICCs for the 6 × 6 mm scans were <0.75, and the CVs were all >10%. Conclusions:The 6 × 6 mm macular angiography scans resulted in lower repeatabilities than the 3 × 3 mm scans according to all OCTA parameters, particularly in the central fovea and FAZ metrics. The 3 × 3 mm scan was more suitable than the 6 × 6 mm scan for analyzing macular microvascular density and FAZ metrics.
journal_name
J Ophthalmoljournal_title
Journal of ophthalmologyauthors
Lim HB,Kang TS,Won YK,Kim JYdoi
10.1155/2020/5686894subject
Has Abstractpub_date
2020-04-17 00:00:00pages
5686894eissn
2090-004Xissn
2090-0058journal_volume
2020pub_type
杂志文章abstract::Aim. To examine subscale and total scores of NEI-VFQ questionnaire of type 2 diabetes patients at different diabetic retinopathy (DRP) stages. Methods. A total number of 201 patients have been included. Prior to ophthalmological examination all patients participated in the NEI-VFQ questionnaire. The patients were divi...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/1549318
更新日期:2016-01-01 00:00:00
abstract::Purpose. To compare near, intermediate, and distance vision and quality of vision, when refractive rotational multifocal intraocular lenses with 3.0 diopters or diffractive multifocal intraocular lenses with 2.5 diopters near addition are implanted. Methods. 41 eyes of 41 patients in whom rotational +3.0 diopters near...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/1395302
更新日期:2016-01-01 00:00:00
abstract::Purpose. To describe morphology of lamellar hole-associated epiretinal proliferation (LHEP) removed from eyes with lamellar macular holes (LMH). Methods. Based on optical coherence tomography data, 10 specimens of LHEP were removed from 10 eyes with LMH during standard vitrectomy. Specimens were prepared for correlati...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/450212
更新日期:2015-01-01 00:00:00
abstract::Current data permit only speculations regarding sex differences in the prevalence of infectious uveitis between women and men because uveitis case surveys do not uniformly report gender data. Differences in prevalence that are reported in the literature could relate to simple differences in the number of women and men...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2014/683246
更新日期:2014-01-01 00:00:00
abstract:Background:For so long, corneal diseases have been known as one of the leading causes to blindness in the global. This blindness might be due to failure to accept the corneal transplantation. Therefore, this study aimed to determine the prevalence and the root challenges for corneal transplantation acceptance at the Un...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/4560649
更新日期:2019-12-13 00:00:00
abstract:Purpose:To evaluate the efficacy and safety of the simultaneous use of short-term perfluoro-n-octane (PFO) with perfluoropropane (C3F8) gas to achieve retinal reattachment in eyes with rhegmatogenous retinal detachment (RRD) with proliferative vitreoretinopathy (PVR) grade C and multiple retinal breaks including inferi...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/6938627
更新日期:2020-10-07 00:00:00
abstract::LASIK eye surgery has become a very common practice for myopic people, especially those in the military. Sometimes undertaken by people who need to keep a specific medical aptitude, this surgery could be performed in secret from the hierarchy and from the institute medical staff. However, even though the eyes have bee...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2014/762364
更新日期:2014-01-01 00:00:00
abstract::Purpose. To investigate the thickness of the retinal nerve fiber layer (RNFL) and choroid in patients who have migraines in comparison to healthy controls. Methods. This study included 76 eyes and patients in the migraine group, 36 with aura (MWA group) and 40 without (MWoA group), and 38 eyes as control subjects. The...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/868967
更新日期:2015-01-01 00:00:00
abstract::The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or apoptosis patterns of photoreceptors are still unclear in rd11 mi...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/9721362
更新日期:2017-01-01 00:00:00
abstract:Purpose:To examine the current knowledge about the age-related processes in the anterior segment of the eye at a biological, clinical, and molecular level. Methods:We reviewed the available published literature that addresses the aging process of the anterior segment of the eye and its associated molecular and physiol...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2017/1295132
更新日期:2017-01-01 00:00:00
abstract::Purpose. To assess the morphology of idiopathic choroidal neovascularization (ICNV) by optical coherence tomography angiography (OCTA) and determine the therapeutic effects of intravitreal antivascular endothelial growth factor (anti-VEGF). Method. Patients with naive ICNV were assessed by spectral domain optical cohe...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/5608250
更新日期:2016-01-01 00:00:00
abstract::This paper demonstrates multiple benefits of intravitreal bevacizumab (IVB) on diabetic retinopathy (DR) including diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) at 24 months of followup. This is a retrospective multicenter interventional comparative case series of intravitreal injections of...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2011/584238
更新日期:2011-01-01 00:00:00
abstract::Objective. Compare glaucoma medication costs between the United States (USA) and Canada. Methods. We modelled glaucoma brand name and generic medication annual costs in the USA and Canada based on October 2013 Costco prices and previously reported bottle overfill rates, drops per mL, and wastage adjustment. We also ca...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2015/547960
更新日期:2015-01-01 00:00:00
abstract:Objective:To evaluate optical coherence tomography (OCT) findings of pediatric Alport syndrome (AS) patients with no retinal pathology on fundus examination. Materials and Methods:Twenty-one patients being followed up with the diagnosis of AS (Group 1) and 24 age- and sex-matched healthy volunteers (Group 2) were pros...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/6741930
更新日期:2019-01-21 00:00:00
abstract:Purpose:One of the most difficult refractory glaucomas is the neovascular type (NVG), and its association with dense cataract adds to this difficulty. This study aimed to provide results of the triple surgical procedure for such conditions. Methods:12 eyes of 12 patients with NVG and dense cataract were included in th...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/1251203
更新日期:2020-06-21 00:00:00
abstract::Purpose. To investigate the agreement between morphometric optic nerve head parameters assessed with the confocal laser ophthalmoscope HRT III and the stereoscopic fundus camera Kowa nonmyd WX3D retrospectively. Methods. Morphometric optic nerve head parameters of 40 eyes of 40 patients with primary open angle glaucom...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/4764857
更新日期:2016-01-01 00:00:00
abstract:Background:The advantage of using an autostereoscopic smartphone is that it can achieve 3D effects without the need for glasses. The purpose of this study was to evaluate whether this technology could be utilized to detect stereoacuity. Methods:An autostereoscopic smartphone was used to imitate Lang stereotest I & II,...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/1570309
更新日期:2019-10-31 00:00:00
abstract::Purpose. To compare the mean corneal power (Km) and total astigmatism (Ka) estimated by three methods: simulated keratometry (simK), true net power (TNP), and total corneal refractive power (TCRP) before and after femtosecond laser small incision lenticule extraction (SMILE) surgery. Methods. A retrospective, cross-se...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/9659481
更新日期:2017-01-01 00:00:00
abstract::Genome-wide association study (GWAS) analysis identified three new susceptibility loci for PACG. In this study, we aimed to investigate whether these three loci in PLEKHA7, COL11A1, and PCMTD1-ST18 are associated with PAC and ocular biometric characteristics, such as axial length (AL), anterior chamber depth (ACD), an...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2013/641596
更新日期:2013-01-01 00:00:00
abstract::Central retinal vein occlusion (CRVO) is a common retinal disease. Recent works mentioned spontaneous retinal arterial pulsations (SRAPs) as a feature of some CRVOs. This is a retrospective study on patients presenting with CRVO who were followed up for at least 6 months. The objective was to identify SRAP in the acut...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/3107472
更新日期:2020-06-09 00:00:00
abstract::Zeaxanthin is a nutritional carotenoid with a considerable amount of safety data based on regulatory studies, which form the basis of its safety evaluation. Subchronic OECD guideline studies with mice and rats receiving beadlet formulations of high purity synthetic zeaxanthin in the diet at dosages up to 1000 mg/kg bo...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2016/3690140
更新日期:2016-01-01 00:00:00
abstract:Purpose:Studying the early effect of different extraocular muscle (EOM) surgeries on corneal biomechanics. Subjects and methods:This is a prospective, nonrandomized, interventional study, in which 42 eyes of 29 candidates for EOM surgery for strabismus correction at Cairo university hospitals, aged 14-37 years, were r...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/8072140
更新日期:2018-09-16 00:00:00
abstract::Ocular complications associated with cutaneous lupus erythematosus (CLE) are less studied compared with those ones associated with systemic lupus erythematosus (SLE). The main ocular sites involved in patients affected by discoid lupus erythematosus (DLE) are eyelids followed by orbit and periorbit, the least being co...
journal_title:Journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1155/2015/254260
更新日期:2015-01-01 00:00:00
abstract:Purpose:To examine and spot systemic findings commonly associated with a serious form of ocular Behcet's disease. This could potentially help ophthalmologists categorize their patients based on future risk and plan treatment accordingly. Subjects and Methods:The data of 249 patients with Behcet's disease were examined...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/9518065
更新日期:2018-04-26 00:00:00
abstract:Purpose:To evaluate the changes in retinal vessel density and thickness after small incision lenticule extraction (SMILE) with optical coherence tomography angiography (OCTA) in myopic patients. Methods:In this prospective study, SMILE surgeries were done in 46 eyes of 24 patients with spherical equivalent (SE) more t...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2019/3693140
更新日期:2019-05-20 00:00:00
abstract:Objective:This study aims to describe the clinical manifestations and outcomes in a cohort of older Chinese patients. Method:A retrospective study of patients aged ≥ 45 years who had a first episode of optic neuritis (ON) between May 2008 and November 2012. Clinical features at onset and last follow-up were analyzed w...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2017/3458356
更新日期:2017-01-01 00:00:00
abstract:Purpose:Glaucoma is the leading cause of irreversible blindness throughout the world. The pathogenesis of glaucoma is complex, and neuroprotection is a crucial aspect of therapy. High concentrations of extracellular glutamate are toxic to the optic nerve. The glutamate-aspartate transporter (GLAST) in retinal Müller ce...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2018/6128470
更新日期:2018-10-31 00:00:00
abstract:Purpose:Observation of ocular structures using microscope-integrated intraoperative optical coherence tomography (iOCT) has been adopted. Using the novel digital ophthalmic microscope, ARTEVO 800 with iOCT, we tested the feasibility of trabecular meshwork (TM) imaging during microhook ab interno trabeculotomy, a minima...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2020/9024241
更新日期:2020-07-17 00:00:00
abstract::Background. We aimed to evaluate the association between maternal smoking and the occurrence of childhood refractive error and amblyopia. Methods. Relevant articles were identified from PubMed and EMBASE up to May 2015. Combined odds ratio (OR) corresponding with its 95% confidence interval (CI) was calculated to eval...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2016/8263832
更新日期:2016-01-01 00:00:00
abstract::Purpose. To compare anterior chamber depth (ACD), representing the distance between the anterior corneal surface and anterior lens surface measurements between the Galilei Dual Scheimpflug Analyzer and the IOLMaster. Methods. A retrospective review of 65 individual patient eyes with normal anterior segments, and no pr...
journal_title:Journal of ophthalmology
pub_type: 杂志文章
doi:10.1155/2012/430249
更新日期:2012-01-01 00:00:00