Abstract：
:In the last decade, extracellular vesicles (EVs) have become a hot topic. The findings on EVs content and effects have made them a major field of interest in cancer research. EVs, are able to be internalized through integrins expressed in parental cells, in a tissue specific manner, as a key step of cancer progression and pre-metastatic niche formation. However, this specificity might lead to new opportunities in cancer treatment by using EVs as devices for drug delivery. For future applications of EVs in cancer, improved protocols and methods for EVs isolation and visualization are required. Our group has put efforts on developing a protocol able to track the EVs for in vivo internalization analysis. We showed, for the first time, the videos of labeled EVs uptake by living lung cancer cells.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Reclusa P,Verstraelen P,Taverna S,Gunasekaran M,Pucci M,Pintelon I,Claes N,de Miguel-Pérez D,Alessandro R,Bals S,Kaushal S,Rolfo Cdoi
10.1038/s41598-020-62920-0subject
Has Abstractpub_date
2020-04-16 00:00:00pages
6494issue
1issn
2045-2322pii
10.1038/s41598-020-62920-0journal_volume
10pub_type
杂志文章abstract：:The current assessment of corneal vascularisation (CV) relies on slit-lamp examination, which may be subjective. Dye-based angiographies, like indocyanine green angiography (ICGA), allows for good visualisation of anterior segment blood vessels. However, ICGA is invasive and can be associated with systemic adverse eff...
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更新日期：2021-01-13 00:00:00
abstract：:The natural bacterial diversity is regarded as a treasure trove for natural products. However, accessing complex cell mixtures derived from environmental samples in standardized high-throughput screenings is challenging. Here, we present a droplet-based microfluidic platform for ultrahigh-throughput screenings able to...
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2015-05-19 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-07-14 00:00:00
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journal_title：Scientific reports
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更新日期：2017-11-08 00:00:00
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journal_title：Scientific reports
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更新日期：2015-12-04 00:00:00
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pub_type： 杂志文章,meta分析
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journal_title：Scientific reports
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更新日期：2016-09-15 00:00:00
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journal_title：Scientific reports
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journal_title：Scientific reports
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