Targeting HCCR expression resensitizes gastric cancer cells to chemotherapy via down-regulating the activation of STAT3.

abstract：:The majority of colorectal cancer (CRC) arises from precursor lesions known as polyps. The molecular determinants that distinguish benign from malignant polyps remain unclear. To molecularly characterize polyps, we utilized Cancer Adjacent Polyp (CAP) and Cancer Free Polyp (CFP) patients. CAPs had tissues from the res...

journal_title：Scientific reports

authors： Druliner BR,Wang P,Bae T,Baheti S,Slettedahl S,Mahoney D,Vasmatzis N,Xu H,Kim M,Bockol M,O'Brien D,Grill D,Warner N,Munoz-Gomez M,Kossick K,Johnson R,Mouchli M,Felmlee-Devine D,Washechek-Aletto J,Smyrk T,Oberg A,

更新日期：2018-02-16 00:00:00

abstract：:The present work presents and discusses the results of a comprehensive study on the bioactive properties of Nb-substituted silicate glass derived from 45S5 bioglass. In vitro and in vivo experiments were performed. We undertook three different types of in vitro analyses: (i) investigation of the kinetics of chemical r...

journal_title：Scientific reports

authors： Souza L,Lopes JH,Encarnação D,Mazali IO,Martin RA,Camilli JA,Bertran CA

更新日期：2018-08-24 00:00:00

abstract：:Nickel-titanium-oxide (Ni-Ti-O) nanotube arrays (NTAs) prepared on nearly equiatomic NiTi alloy shall have broad application potential such as for energy storage and biomedicine, but their precise structure control is a great challenge because of the high content of alloying element of Ni, a non-valve metal that canno...

journal_title：Scientific reports

authors： Hang R,Liu Y,Zhao L,Gao A,Bai L,Huang X,Zhang X,Tang B,Chu PK

更新日期：2014-12-18 00:00:00

abstract：:In lung cancer a deregulation of Transforming Growth Factor-β (TGFβ) signaling has been observed. Yet, the impact of TGFβ in squamous cell carcinoma of the lung (LUSC) remained to be determined. We combined phenotypic and transcriptome-wide studies and showed that the stimulation of the LUSC cell line SK-MES1 with TGF...

journal_title：Scientific reports

authors： Dvornikov D,Schneider MA,Ohse S,Szczygieł M,Titkova I,Rosenblatt M,Muley T,Warth A,Herth FJ,Dienemann H,Thomas M,Timmer J,Schilling M,Busch H,Boerries M,Meister M,Klingmüller U

更新日期：2018-06-22 00:00:00

abstract：:Albacore tuna (Thunnus alalunga) is an important target of tuna fisheries in the Atlantic and Indian Oceans. The commercial catch of albacore is the highest globally among all temperate tuna species, contributing around 6% in weight to global tuna catches over the last decade. The accurate assessment and management of...

journal_title：Scientific reports

authors： Nikolic N,Montes I,Lalire M,Puech A,Bodin N,Arnaud-Haond S,Kerwath S,Corse E,Gaspar P,Hollanda S,Bourjea J,West W,Bonhommeau S

更新日期：2020-09-24 00:00:00

abstract：:The LiBH4/CaH2 composite are firstly studied as Concentrating Solar Power Thermal Storage Material. The LiBH4/CaH2 composite according to the stoichiometric ratio are synthesized by high-energy ball milling method. The kinetics, thermodynamics and cycling stability of LiBH4/CaH2 composite are investigated by XRD (X-ra...

journal_title：Scientific reports

authors： Li Y,Li P,Qu X

更新日期：2017-01-31 00:00:00

abstract：:The Maxwellian near-eye displays have attracted growing interest in various applications. By using a confined pupil, a Maxwellian display presents an all-in-focus image to the viewer where the image formed on the retina is independent of the optical power of the eye. Despite being a promising technique, current Maxwel...

journal_title：Scientific reports

authors： Chang C,Cui W,Park J,Gao L

更新日期：2019-12-10 00:00:00

abstract：:Since domestication, a large number of livestock breeds adapted to local conditions have been created by natural and artificial selection, representing one of the most powerful ways in which human groups have constructed niches to meet their need. Although many authors have described local breeds as the result of cult...

journal_title：Scientific reports

authors： Colino-Rabanal VJ,Rodríguez-Díaz R,Blanco-Villegas MJ,Peris SJ,Lizana M

更新日期：2018-04-24 00:00:00

abstract：:Polarimetric imaging has proved its value in medical diagnostics, bionics, remote sensing, astronomy, and in many other wide fields. Pixel-level solid monolithically integrated polarimetric imaging photo-detectors are the trend for infrared polarimetric imaging devices. For better polarimetric imaging performance the ...

journal_title：Scientific reports

authors： Li Q,Li Z,Li N,Chen X,Chen P,Shen X,Lu W

更新日期：2014-09-11 00:00:00

abstract：:Textile forms of solar cells possess special advantages over other types of solar cells, including their light weight, high flexibility, and mechanical robustness. Recent demand for wearable devices has promoted interest in the development of high-efficiency textile-based solar cells for energy suppliers. However, the...

journal_title：Scientific reports

authors： Yun MJ,Cha SI,Seo SH,Lee DY

更新日期：2014-06-24 00:00:00

abstract：:Alcohol and nicotine are the most widely co-abused drugs. Both modify the activity of dopaminergic (DA) neurons of the Ventral Tegmental Area (VTA) and lead to an increase in DA release in the Nucleus Accumbens, thereby affecting the reward system. Evidences support the hypothesis that distinct nicotinic acetylcholine...

journal_title：Scientific reports

authors： Tolu S,Marti F,Morel C,Perrier C,Torquet N,Pons S,de Beaurepaire R,Faure P

更新日期：2017-03-23 00:00:00

abstract：:rag1 -/- zebrafish have been employed in immunological research as a useful immunodeficient vertebrate model, but with only fragmentary evidence for the lack of functional adaptive immunity. rag1-null zebrafish exhibit differences from their human and murine counterparts in that they can be maintained without any spec...

journal_title：Scientific reports

authors： Tokunaga Y,Shirouzu M,Sugahara R,Yoshiura Y,Kiryu I,Ototake M,Nagasawa T,Somamoto T,Nakao M

更新日期：2017-08-08 00:00:00

abstract：:The elemental two-dimensional (2D) materials such as graphene, silicene, germanene, and black phosphorus have attracted considerable attention due to their fascinating physical properties. Structurally they possess the honeycomb or distorted honeycomb lattices, which are composed of six-atom rings. Here we find a new ...

journal_title：Scientific reports

authors： Li P,Luo W

更新日期：2016-05-06 00:00:00

abstract：:Aging is a multifactorial process that results in progressive loss of regenerative capacity and tissue function while simultaneously favoring the development of a large array of age-related diseases. Evidence suggests that the accumulation of senescent cells in tissue promotes both normal and pathological aging. Oxic ...

journal_title：Scientific reports

authors： Ottaviani A,Eid R,Zoccola D,Pousse M,Dubal JM,Barajas E,Jamet K,Lebrigand K,Lapébie P,Baudoin C,Giraud-Panis MJ,Rouan A,Beauchef G,Guéré C,Vié K,Barbry P,Tambutté S,Gilson E,Allemand D

更新日期：2020-11-17 00:00:00

abstract：:Spotted seal (Phoca largha) is a critically endangered pinniped in China and South Korea. The conventional method to protect and maintain the P. largha population is to keep them captive in artificially controlled environments. However, little is known about the physiological differences between wild and captive P. la...

journal_title：Scientific reports

authors： Tian J,Du J,Han J,Bao X,Song X,Lu Z

更新日期：2020-10-30 00:00:00

abstract：:The G protein-coupled receptor opsin is a phospholipid scramblase that facilitates rapid transbilayer phospholipid exchange in liposomes. The mechanism by which opsin scrambles lipids is unknown. It has been proposed that lipid translocation may occur at protein-protein interfaces of opsin dimers. To test this possibi...

journal_title：Scientific reports

authors： Pandey K,Ploier B,Goren MA,Levitz J,Khelashvili G,Menon AK

更新日期：2017-12-01 00:00:00

abstract：:This study aimed to define the width and length of the dental arch in 12-year-old Vietnamese children, and to elucidate differences between genders and among ethnic groups. A cross-sectional study was conducted in 4565 12 years-old children from the 4 major ethnic groups in Vietnam (Kinh, Muong, Thai, and Tay), with a...

journal_title：Scientific reports

authors： Dung TM,Ngoc VTN,Hiep NH,Khoi TD,Xiem VV,Chu-Dinh T,Cieslar-Pobuda A,Stoufi E,Show PL,Tao Y,Bac ND,Van Ba N,Le QA,Pham VH,Chu DT

更新日期：2019-02-28 00:00:00

abstract：:Transmembrane receptor clustering is a ubiquitous phenomenon in pro- and eukaryotic cells to physically sense receptor/ligand interactions and subsequently translate an exogenous signal into a cellular response. Despite that receptor cluster formation has been described for a wide variety of receptors, ranging from ch...

journal_title：Scientific reports

authors： Becker B,Shaebani MR,Rammo D,Bubel T,Santen L,Schmitt MJ

更新日期：2016-06-29 00:00:00

abstract：:Oxytocin (OXT) is an important neuromodulator of social behaviors via activation of both oxytocin receptors (OXTR) and vasopressin (AVP) 1a receptors (AVPR1a). Marmosets are neotropical primates with a modified OXT ligand (Pro8-OXT), and this ligand shows significant coevolution with traits including social monogamy a...

journal_title：Scientific reports

authors： Mustoe A,Schulte NA,Taylor JH,French JA,Toews ML

更新日期：2019-10-29 00:00:00

abstract：:ADC is a potential post treatment imaging biomarker in colorectal liver metastasis however measurements are affected by respiratory motion. This is compounded by increased statistical uncertainty in ADC measurement with decreasing tumour volume. In this prospective study we applied a retrospective motion correction me...

journal_title：Scientific reports

authors： Pathak R,Tian J,Thacker NA,Morris DM,Ragheb H,Saunders C,Saunders M,Jackson A

更新日期：2019-03-07 00:00:00

abstract：:A series of nanocomposites of cobalt embedded in N-doped nanoporous carbons, carbon nanotubes or hollow carbon onions have been synthesized by a one-step carbonization of metal-organic-framework ZIF-67. The effect of the carbonization temperature on the structural evolution of the resulting nanocomposites has been inv...

journal_title：Scientific reports

authors： Chen B,Ma G,Zhu Y,Xia Y

更新日期：2017-07-13 00:00:00

abstract：:Geographical origin determination of white rice has become the major issue of food industry. However, there is still lack of a high-throughput method for rapidly and reproducibly differentiating the geographical origins of commercial white rice. In this study, we developed a method that employed lipidomics and deep le...

journal_title：Scientific reports

authors： Long NP,Lim DK,Mo C,Kim G,Kwon SW

更新日期：2017-08-17 00:00:00

abstract：:Culturomics is a high-throughput culture approach that has dramatically contributed to the recent renewal of culture. While metagenomics enabled substantial advances in exploring the microbiota, culturomics significantly expanded our knowledge regarding the bacterial gut repertoire through the discovery and the descri...

journal_title：Scientific reports

authors： Diakite A,Dubourg G,Dione N,Afouda P,Bellali S,Ngom II,Valles C,Tall ML,Lagier JC,Raoult D

更新日期：2020-06-15 00:00:00

abstract：:Catharanthus roseus is a commercial source for anti-cancer terpenoid indole alkaloids (TIAs: vincristine and vinblastine). Inherent levels of these TIAs are very low, hence research studies need to focus on enhancing their levels in planta. Since primary metabolism provides precursors for specialized-metabolism, eleva...

journal_title：Scientific reports

authors： Nishanth MJ,Sheshadri SA,Rathore SS,Srinidhi S,Simon B

更新日期：2018-10-10 00:00:00

abstract：:In the Ultimatum Game, two players are offered a chance to win a pie. The proposer suggests how to split the pie. The responder can either accept or reject the deal. If an agreement is not reached, neither player gets anything. Both game theory and evolutionary game theory predict the rational solution that the propos...

journal_title：Scientific reports

authors： Wang X,Chen X,Wang L

更新日期：2014-04-01 00:00:00

abstract：:The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases. The release of EVs by Trypanosoma cruzi, the causative agent of Chagas disease, has recently been described, with different protein cargoes including the MA...

journal_title：Scientific reports

authors： Díaz Lozano IM,De Pablos LM,Longhi SA,Zago MP,Schijman AG,Osuna A

更新日期：2017-03-15 00:00:00

abstract：:Nanoscale wavelength-converted optical components are promising components for communication and optical information processing in integrated photonic system. In this work, we report a facile strategy for realizing continuously tunable wavelength-converted wave-guiding in dye-doped nanofibers. The nanofibers with diam...

journal_title：Scientific reports

authors： Yu H,Li B

更新日期：2013-01-01 00:00:00

abstract：:In the field of correlative microscopy, light and electron microscopy form a powerful combination for morphological analyses in zoology. Due to sample thickness limitations, these imaging techniques often require sectioning to investigate small animals and thereby suffer from various artefacts. A recently introduced n...

journal_title：Scientific reports

authors： Ferstl S,Schwaha T,Ruthensteiner B,Hehn L,Allner S,Müller M,Dierolf M,Achterhold K,Pfeiffer F

更新日期：2020-03-03 00:00:00

abstract：:In this study the damselfly Ischnura senegalensis (Rambur, 1842) was first found to produce strong photoluminescence (PL) emissions from various colored-body portions, such as the eighth abdominal segment of the tail. The colors of the colored-body portions can be enhanced or modified by the PL emissions for assistanc...

journal_title：Scientific reports

authors： Chuang CJ,Liu CD,Patil RA,Wu CC,Chang YC,Peng CW,Chao TK,Liou JW,Liou Y,Ma YR

更新日期：2016-12-14 00:00:00

abstract：:In this work the chalcopyrite CuIn3Se5-xTex (x = 0~0.5) with space group through isoelectronic substitution of Te for Se have been prepared, and the crystal structure dilation has been observed with increasing Te content. This substitution allows the anion position displacement ∆u = 0.25-u to be zero at x ≈ 0.15. Howe...

journal_title：Scientific reports

authors： Lu Y,Chen S,Wu W,Du Z,Chao Y,Cui J

更新日期：2017-01-06 00:00:00