Abstract:
:Geographical origin determination of white rice has become the major issue of food industry. However, there is still lack of a high-throughput method for rapidly and reproducibly differentiating the geographical origins of commercial white rice. In this study, we developed a method that employed lipidomics and deep learning to discriminate white rice from Korea to China. A total of 126 white rice of 30 cultivars from different regions were utilized for the method development and validation. By using direct infusion-mass spectrometry-based targeted lipidomics, 17 lysoglycerophospholipids were simultaneously characterized within minutes per sample. Unsupervised data exploration showed a noticeable overlap of white rice between two countries. In addition, lysophosphatidylcholines (lysoPCs) were prominent in white rice from Korea while lysophosphatidylethanolamines (lysoPEs) were enriched in white rice from China. A deep learning prediction model was built using 2014 white rice and validated using two different batches of 2015 white rice. The model accurately discriminated white rice from two countries. Among 10 selected predictors, lysoPC(18:2), lysoPC(14:0), and lysoPE(16:0) were the three most important features. Random forest and gradient boosting machine models also worked well in this circumstance. In conclusion, this study provides an architecture for high-throughput classification of white rice from different geographical origins.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Long NP,Lim DK,Mo C,Kim G,Kwon SWdoi
10.1038/s41598-017-08892-0subject
Has Abstractpub_date
2017-08-17 00:00:00pages
8552issue
1issn
2045-2322pii
10.1038/s41598-017-08892-0journal_volume
7pub_type
杂志文章abstract::Integrated photonics promises solutions to questions of stability, complexity, and size in quantum optics. Advances in tunable and non-planar integrated platforms, such as laser-inscribed photonics, continue to bring the realisation of quantum advantages in computation and metrology ever closer, perhaps most easily se...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09601
更新日期:2015-04-27 00:00:00
abstract::Subcortical ischemic vascular dementia (SIVD) caused by chronic cerebral hypoperfusion develops with progressive white matter and cognitive impairments, yet no effective therapy is available. We investigated the temporal effects of minocycline on an experimental SIVD exerted by right unilateral common carotid arteries...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12079
更新日期:2015-07-15 00:00:00
abstract::Olanzapine is a second-generation antipsychotic (AP) drug commonly prescribed for the treatment of schizophrenia. Recently, olanzapine has been found to cause brain tissue volume loss in rodent and primate studies; however, the underlying mechanism remains unknown. Abnormal autophagy and oxidative stress have been imp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75356-3
更新日期:2020-11-05 00:00:00
abstract::The bilateral controlled NOT (CNOT) operation plays a key role in standard entanglement purification process, but the CNOT operation may not be the optimal joint operation in the sense that the output entanglement is maximized. In this paper, the CNOT operations in both the Schmidt-projection based entanglement concen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25958
更新日期:2016-05-18 00:00:00
abstract::Numerous neurological dysfunctions are characterized by undesirable nerve activity. By providing reversible nerve blockage, electric stimulation with an implanted electrode holds promise in the treatment of these conditions. However, there are several limitations to its application, including poor bio-compatibility an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74891-3
更新日期:2020-10-22 00:00:00
abstract::Human protein tyrosine phosphatase non-receptor type 4 (PTPN4) has been shown to prevent cell death. The active form of human PTPN4 consists of two globular domains, a PDZ (PSD-95/Dlg/ZO-1) domain and a phosphatase domain, tethered by a flexible linker. Targeting its PDZ domain abrogates this protection and triggers a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08193-6
更新日期:2017-08-11 00:00:00
abstract::Recently, a new class of nonlinear systems was introduced, in which the self-trapping of fundamental and vortical localized modes in space of dimension D is supported by cubic self-repulsion with a strength growing as a function of the distance from the center, r, at any rate faster that r(D). These systems support ro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09420
更新日期:2015-03-24 00:00:00
abstract::Telomere DNA ends with a single-stranded 3' overhang. Long 3' overhangs may cause aberrant DNA damage responses and accelerate telomere attrition, which is associated with cancer and aging, respectively. Genetic studies have indicated several important players in preventing 5' end hyper-resection, yet detailed knowled...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08663-x
更新日期:2017-08-18 00:00:00
abstract::From 2010 to 2012, large outbreaks of EV-A71-related- hand foot and mouth disease (HFMD) occurred annually in China. Some cases had neurological complications and were closely associated with fatal cardiopulmonary collapse, but not all children with central nervous system (CNS) involvement demonstrated a poor prognosi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23444
更新日期:2016-03-22 00:00:00
abstract::Raman spectroscopy is a powerful analytical method that allows deposited and/or immobilized cells to be evaluated without complex sample preparation or labeling. However, a main limitation of Raman spectroscopy in cell analysis is the extremely weak Raman intensity that results in low signal to noise ratios. Therefore...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13150
更新日期:2015-08-27 00:00:00
abstract::Globally, there has been an increase in the use of herbal remedies including traditional Chinese medicine (TCM). There is a perception that products are natural, safe and effectively regulated, however, regulatory agencies are hampered by a lack of a toolkit to audit ingredient lists, adulterants and constituent activ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17475
更新日期:2015-12-10 00:00:00
abstract::High fat diet (HFD)-induced metabolic disorders may lead to emotional disorders. This study aimed to explore the effect of simvastatin (SMV) and bezafibrate (BZ) on improving HFD-induced emotional changes, and tried to identify their different mechanisms. The intraperitoneal glucose tolerance test (IPGTT) was used to ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02576-5
更新日期:2017-05-24 00:00:00
abstract::Leaf nutrient resorption is an important mechanism in adapting to adverse environments. However, few studies examine how nutrient resorption responds to phosphorus (P) and potassium (K) fertilization or to a shift in nutrient limitation due to water supply and fertilization. On the Loess Plateau of China, we treated l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65484-1
更新日期:2020-06-29 00:00:00
abstract::Given that many fundamental questions in neuroscience are still open, it seems pertinent to explore whether the brain might use other physical modalities than the ones that have been discovered so far. In particular it is well established that neurons can emit photons, which prompts the question whether these biophoto...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36508
更新日期:2016-11-07 00:00:00
abstract::Three-dimensional (3D) image reconstruction of tumors based on serial histological sectioning is one of the most powerful methods for accurate high-resolution visualization of tumor structures. However, 3D histological reconstruction of whole tumor has not yet been achieved. We established a high-resolution 3D model o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76081-7
更新日期:2020-11-03 00:00:00
abstract::Perpendicular magnetization and precise control over the magnetic easy axis in magnetic thin film is necessary for a variety of applications, particularly in magnetic recording media. A strong (111) orientation is successfully achieved in the CoFe2O4 (CFO) thin film at relatively low substrate temperature of 100 °C, w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30074
更新日期:2016-07-20 00:00:00
abstract::In this paper, we analyze the synchronization problem of master-slave probabilistic Boolean networks (PBNs). The master Boolean network (BN) is a deterministic BN, while the slave BN is determined by a series of possible logical functions with certain probability at each discrete time point. In this paper, we firstly ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13437
更新日期:2015-08-28 00:00:00
abstract::Selective pressure from pathogens is considered a key selective force driving the evolution of components of the immune system. Since single components of the immune system may interact with many pathogens, and single pathogens may be recognized by multiple components of the immune system, gaining a better understandi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-26672-2
更新日期:2018-05-30 00:00:00
abstract::Balancing the upper body is pivotal for upright and efficient gait. While models have identified potentially useful characteristics of biarticular thigh muscles for postural control of the upper body, experimental evidence for their specific role is lacking. Based on theoretical findings, we hypothesised that biarticu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50995-3
更新日期:2019-10-10 00:00:00
abstract::A novel chemical absorption-biological reduction (CABR) integrated process, employing ferrous ethylenediaminetetraacetate (Fe(II)EDTA) as a solvent, is deemed as a potential option for NOx removal from the flue gas. Previous work showed that the Fe(II)EDTA concentration was critical for the NOx removal in the CABR pro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18876
更新日期:2016-01-08 00:00:00
abstract::Induction of autophagy can have beneficial effects in several human diseases, e.g. cancer and neurodegenerative diseases (ND). Here, we therefore evaluated the potential of two novel autophagy-inducing compounds, i.e. STF-62247 and pimozide, to stimulate autophagy as well as autophagic cell death (ACD) using mouse emb...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56990-y
更新日期:2020-01-20 00:00:00
abstract::Distinct regions of long-range genetic fixation in the human MHC region, known as conserved extended haplotypes (CEHs), possess unique genomic characteristics and are strongly associated with numerous diseases. While CEHs appear to be homogeneous by SNP analysis, the nature of fine variations within their genomic stru...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16972
更新日期:2015-11-23 00:00:00
abstract::Term preeclampsia (tPE), ≥37 weeks, is the most common form of PE and the most difficult to predict. Little is known about its pathogenesis. This study aims to elucidate the pathogenesis and assess early prediction of tPE using serial integrated metabolomic and proteomic systems biology approaches. Serial first- (11-1...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15882-9
更新日期:2017-11-23 00:00:00
abstract::To evaluate the performance of computed high b value diffusion-weighted images (DWI) in prostate cancer detection. 97 consecutive patients who had undergone multiparametric MRI of the prostate followed by biopsy were reviewed. Five radiologists independently scored 138 lesions on native high b-value images (b = 1200 s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21523-6
更新日期:2018-02-21 00:00:00
abstract::The investigation of chemical and structural dynamics in battery materials is essential to elucidation of structure-property relationships for rational design of advanced battery materials. Spatially resolved techniques, such as scanning/transmission electron microscopy (S/TEM), are widely applied to address this chal...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05694
更新日期:2014-07-16 00:00:00
abstract::Novel-morphological Fe3O4 nanosheets with magnetochromatic property have been prepared by a modified solvothermal method. Such nanosheets could form one-dimension photonic crystal under an external magnetic field. The Fe3O4 nanosheets suspension could strongly diffract visible light and display varied colors with chan...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09320
更新日期:2015-03-23 00:00:00
abstract::Cardiac arrhythmias are often associated with mutations in ion channels or other proteins. To enable drug development for distinct arrhythmias, model systems are required that allow implementing patient-specific mutations. We assessed a muscular pump in Caenorhabditis elegans. The pharynx utilizes homologues of most o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14427
更新日期:2015-09-24 00:00:00
abstract::IL-37 is a novel pro-angiogenic cytokine that potently promotes endothelial cell activation and pathological angiogenesis in our previous study, but the mechanisms behind the pro-angiogenic effect of IL-37 are less well understood. Extending our observations, we found that TGF-β interacts with IL-37, and potently enha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06124-z
更新日期:2017-07-21 00:00:00
abstract::Attosecond (asec) X-ray free-electron laser (XFEL) has attracted considerable interest over the past years. Nowadays typical XFEL application experiments demand 1010-1011 photons per pulse, which corresponds to a peak power of terawatts (TW) in case of asec hard X-ray pulse. To the realization of such TW asec-XFEL pul...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-57905-y
更新日期:2020-01-28 00:00:00
abstract::Forest fragmentation threatens the ecosystem carbon (C) storage. The distribution patterns of ecosystem C density are poorly documented for fragmented forests of differing patch size. The objectives of this study were to examine C density in these forest ecosystems and the influence of edge effects on C density. Allom...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13598-4
更新日期:2017-10-13 00:00:00