Abstract：
:In this study, cyclodextrin metal-organic framework/chitosan (CD-MOF/CS) nanocapsules, which have a hydrophobic core and a hydrophilic shell, were fabricated as delivery systems for bioactive agents. The nanocapsules were prepared by electrostatic deposition of cationic chitosan onto the anionic CD-MOF core. The presence of the CS coating reduced the mean diameter and polydispersity index of the nanocapsules, which was attributed to their ability to inhibit particle aggregation. Moreover, the encapsulation efficiency of resveratrol within the nanocapsules increased appreciably after coating them with chitosan (from 66.5 to 91.3%). The chitosan coating was also shown to increase the antioxidant activity and photostability of the encapsulated resveratrol. Information about the binding interactions of the resveratrol with the nanocapsules was obtained using fluorescence spectroscopy, infrared spectroscopy, and thermal analysis. The new nanocapsules created in this study may have applications for the encapsulation, protection, and delivery of bioactive agents in food, supplement, and pharmaceutical applications.
journal_name
Food Chemjournal_title
Food chemistryauthors
Qiu C,Julian McClements D,Jin Z,Qin Y,Hu Y,Xu X,Wang Jdoi
10.1016/j.foodchem.2020.126328subject
Has Abstractpub_date
2020-07-01 00:00:00pages
126328eissn
0308-8146issn
1873-7072pii
S0308-8146(20)30179-5journal_volume
317pub_type
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