Structure characterization of a novel neutral polysaccharide isolated from Ganoderma lucidum fruiting bodies.

Abstract:

:Ganoderma lucidum (G. lucidum) is a mushroom which has been used for health promotion for a long time in China. In the present work a neutral hetero-polysaccharide, named FYGL-1, was isolated from FYGL which was reported previously capable of antihyperglycemia in vivo for further detailed chemical structure investigation. The results of monosaccharide composition and GPC analysis indicated that FYGL-1 consisted of galactose, rhamnose and glucose in mole ratio of 1.00:1.15:3.22 with a molecular weight of 78kDa. The detailed structure of FYGL-1 was characterized by periodate oxidation, Smith degradation, methylation analysis, along with FT-IR, GC, GC-MS, 1D (1)H and (13)C NMR and 2D NMR (HSQC, COSY, NOESY and TOCSY). Based on the analysis of the results, the structure of the repeating unit of FYGL-1 was established as:

journal_name

Food Chem

journal_title

Food chemistry

authors

Pan D,Wang L,Chen C,Teng B,Wang C,Xu Z,Hu B,Zhou P

doi

10.1016/j.foodchem.2012.05.071

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

1097-103

issue

3

eissn

0308-8146

issn

1873-7072

pii

S0308-8146(12)00902-8

journal_volume

135

pub_type

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