Camel milk lactoferrin reduces the proliferation of colorectal cancer cells and exerts antioxidant and DNA damage inhibitory activities.

Abstract:

:Lactoferrin (Lf), the main iron-binding protein of milk, has biological activities. We have evaluated the potential of camel milk lactoferrin for its ability to inhibit the proliferation of the colon cancer cell line, HCT-116, in vitro, DNA damage and its antioxidant activities for the first time. The antioxidant capacity of Lf was evaluated by different assays, including ferric-reducing/antioxidant power assay (FRAP), free radical-scavenging activity (DPPH), nitric oxide (NO) radical-scavenging assay, total antioxidant activity and DNA damage, compared with vitamin C and rutin.

journal_name

Food Chem

journal_title

Food chemistry

authors

Habib HM,Ibrahim WH,Schneider-Stock R,Hassan HM

doi

10.1016/j.foodchem.2013.03.039

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

148-52

issue

1

eissn

0308-8146

issn

1873-7072

pii

S0308-8146(13)00342-7

journal_volume

141

pub_type

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