Upregulation of SOX11 enhances tamoxifen resistance and promotes epithelial-to-mesenchymal transition via slug in MCF-7 breast cancer cells.

abstract：:Increasing evidence supports the idea that the finite proliferative life span of normal fibroblasts is a differentiation-like phenomenon. If this were correct, an ordered sequence of differential gene expression should be associated with the in vitro progression of cells from low passage to high passage (senescence). ...

journal_title：Journal of cellular physiology

authors： Choi AM,Olsen DR,Cook KG,Deamond SF,Uitto J,Bruce SA

更新日期：1992-04-01 00:00:00

abstract：:We have compared the biological and biochemical properties of recombinant PDGF AA, AB, and BB using three types of fibroblastic cells: NIH/3T3, human skin fibroblast, and fetal bovine aortic smooth muscle. PDGF binding, receptor autophosphorylation, phosphatidyl inositol hydrolysis, as well as chemotactic and mitogeni...

journal_title：Journal of cellular physiology

authors： Grotendorst GR,Igarashi A,Larson R,Soma Y,Charette M

更新日期：1991-11-01 00:00:00

abstract：:Galectin-1 is reported to be upregulated in various human cancers. However, the relationship between galectin-1 expression and cancer prognosis has not been systematically assessed. In this study, we searched PubMed, Web of Science, and Embase to collect all relevant studies and a meta-analysis was performed. We found...

journal_title：Journal of cellular physiology

authors： Huang MY,He JP,Zhang WQ,Liu JL

更新日期：2019-08-01 00:00:00

abstract：:We have recently described a novel nuclear antigen, AF-2, which is related to cell cycle dependent alterations of chromatin structure. We show by two parameter flow cytometry on a cell by cell basis that the antigen is accessible to specific monoclonal antibodies only in mitotic and postmitotic early G1-phase cells. T...

journal_title：Journal of cellular physiology

authors： Pfeffer U,Di Vinci A,Geido E,Vidali G,Giaretti W

更新日期：1991-12-01 00:00:00

abstract：:The possibility that one or both of the synthetic triamines, 1,3,6-triaminohexane and 1,4,7-triaminoheptane, could substitute for the naturally occurring polyamines in the growth of SV-3T3 cells was investigated. It was found that these triamines did lead to a restoration of growth in cells in which spermidine content...

journal_title：Journal of cellular physiology

authors： McGovern KA,Clark RS,Pegg AE

更新日期：1986-05-01 00:00:00

abstract：:Alpha-D-galactose is metabolized in species ranging from E. coli to mammals predominantly via a series of sequential reactions collectively known as the Leloir pathway. Deficiency of any one of these enzymes in humans results in a form of the inherited metabolic disorder, galactosemia, although the symptoms and severi...

journal_title：Journal of cellular physiology

authors： Fridovich-Keil JL

更新日期：2006-12-01 00:00:00

abstract：:Rat 3Y1 cells arrested at early S by hydroxyurea traversed the remainder of S and G2 and completed mitosis after removal of the drug, irrespective of the absence of serum from the culture medium. When cells were deprived of serum for a period between early S and mitosis after removal of hydroxyurea, the cells delayed ...

journal_title：Journal of cellular physiology

authors： Okuda A,Kimura G

更新日期：1982-03-01 00:00:00

abstract：:Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD), are incurable diseases characterized by progressive loss of cognitive or motor function, which construct a serious threat to the life quality of aging populations and their life spans. Apelin is an ...

journal_title：Journal of cellular physiology

authors： Luo H,Han L,Xu J

更新日期：2020-02-01 00:00:00

abstract：:Tobacco smoking is associated with many diseases. Addiction is of the most notorious tobacco-related syndrome and is mainly attributed to nicotine. In this study, we employed Caenorhabditis elegans as a biological model to systemically investigate the effect of chronic nicotine exposure on microRNA (miRNA) expression ...

journal_title：Journal of cellular physiology

authors： Taki FA,Pan X,Zhang B

更新日期：2014-01-01 00:00:00

abstract：:This study establishes a causal link between the limitation of myofibre transitions and modulation of calcineurin activity, during different exercise paradigms. We have designed a new swimming-based training protocol in order to draw a comparison between a high frequency and amplitude exercise (swimming) and low frequ...

journal_title：Journal of cellular physiology

authors： Grondard C,Biondi O,Pariset C,Lopes P,Deforges S,Lécolle S,Gaspera BD,Gallien CL,Chanoine C,Charbonnier F

更新日期：2008-01-01 00:00:00

abstract：:Parathyroid hormone (PTH) greatly increased the level of adenosine 3', 5' cyclic monophosphate (cAMP) in rabbit costal chondrocytes in culture 2 minutes after its addition. PTH, as well as N6 O2' dibutyryl adenosine 3', 5' cyclic monophosphate (DBcAMP) and 8 Bromo adenosine 3', 5' cyclic monophosphate (8 Br-cAMP) indu...

journal_title：Journal of cellular physiology

authors： Takigawa M,Takano T,Suzuki F

更新日期：1981-02-01 00:00:00

abstract：:Breast cancer stem cells (BCSCs) are competent to initiate tumor formation and growth and refractory to conventional therapies. Consequently BCSCs are implicated in tumor recurrence. Many signaling cascades associated with BCSCs are critical for epithelial-to-mesenchymal transition (EMT). We developed a model system t...

journal_title：Journal of cellular physiology

authors： Fritz AJ,Hong D,Boyd J,Kost J,Finstaad KH,Fitzgerald MP,Hanna S,Abuarqoub AH,Malik M,Bushweller J,Tye C,Ghule P,Gordon J,Frietze S,Zaidi SK,Lian JB,Stein JL,Stein GS

更新日期：2020-10-01 00:00:00

abstract：:Cardiac progenitor cells (CPCs) have the potential to differentiate into several cell lineages with the ability to restore in cardiac tissue. Multipotency and self-renewal activity are the crucial characteristics of CPCs. Also, CPCs have promising therapeutic roles in cardiac diseases such as valvular disease, thrombo...

journal_title：Journal of cellular physiology

authors： Yousefi M,Mamipour M,Sokullu SE,Ghaderi S,Amini H,Rahbarghazi R

更新日期：2019-11-01 00:00:00

abstract：:Both mammary gland development and mammary carcinogenesis involve extensive remodeling of the mammary gland extracellular matrix. The expression of four membrane-type matrix metalloproteinases (MT-MMPs) with matrix remodeling potential in development and tumorigenesis was evaluated by in-situ hybridization on mouse ma...

journal_title：Journal of cellular physiology

authors： Szabova L,Yamada SS,Birkedal-Hansen H,Holmbeck K

更新日期：2005-10-01 00:00:00

abstract：:Glutamine is the most abundant free amino acid in the body and is known to play a regulatory role in several cell specific processes including metabolism (e.g., oxidative fuel, gluconeogenic precursor, and lipogenic precursor), cell integrity (apoptosis, cell proliferation), protein synthesis, and degradation, contrac...

journal_title：Journal of cellular physiology

authors： Curi R,Lagranha CJ,Doi SQ,Sellitti DF,Procopio J,Pithon-Curi TC,Corless M,Newsholme P

更新日期：2005-08-01 00:00:00

abstract：:DNA methylation can regulate gene expression and is pivotal in the occurrence and development of bladder cancer. In this study, we analyzed whole-genome DNA methylation on the basis of data from The Cancer Genome Atlas to select epigenetic biomarkers predictive of survival and further understand the molecular mechanis...

journal_title：Journal of cellular physiology

authors： Yang Z,Liu A,Xiong Q,Xue Y,Liu F,Zeng S,Zhang Z,Li Y,Sun Y,Xu C

更新日期：2019-08-01 00:00:00

abstract：:MCOLN1 encodes mucolipin-1 (TRPML1), a member of the transient receptor potential TRPML subfamily of channel proteins. Mutations in MCOLN1 cause mucolipidosis-type IV (MLIV), a lysosomal storage disorder characterized by severe neurologic, ophthalmologic, and gastrointestinal abnormalities. Along with TRPML1, there ar...

journal_title：Journal of cellular physiology

authors： Curcio-Morelli C,Zhang P,Venugopal B,Charles FA,Browning MF,Cantiello HF,Slaugenhaupt SA

更新日期：2010-02-01 00:00:00

abstract：:Modeling breast cancer in the mouse has helped to better define the heterogeneity of human breast cancer. In the recent past, it has become evident that some limitations have restricted the potential benefits that can be achieved with this approach. In this review, we highlight some key points that should be taken int...

journal_title：Journal of cellular physiology

authors： Caligiuri I,Rizzolio F,Boffo S,Giordano A,Toffoli G

更新日期：2012-08-01 00:00:00

abstract：:Production of inflammatory cytokines plays important roles in the response against tissue injury and in host defense. Alterations in the production of inflammatory cytokines may cause local or systemic inflammatory imbalance, culminating in organ failure or lethal systemic inflammation. The cholinergic anti-inflammato...

journal_title：Journal of cellular physiology

authors： Pereira MR,Leite PE

更新日期：2016-09-01 00:00:00

abstract：:A method, based on the differing capacities of cells to adhere to a column of polyester fibres, has been described for separating human bone marrow cells into a nonadherent and an adherent fraction. The effect of this cell separation procedure on colony formation by erythroid progenitor cells was investigated. In cont...

journal_title：Journal of cellular physiology

authors： Aye MT

更新日期：1977-04-01 00:00:00

abstract：:Ganoderma lucidum immunomodulatory protein (FIP-glu) is an active ingredient with potential immunoregulatory functions. The study was conducted to explore the immunomodulatory activities of recombinant FIP-glu (rFIP-glu) and its possible mechanism in macrophage RAW264.7 cells. In vitro assays of biological activity in...

journal_title：Journal of cellular physiology

authors： Li QZ,Chang YZ,He ZM,Chen L,Zhou XW

更新日期：2019-12-01 00:00:00

abstract：:COVID-19, a new disease caused by the 2019-novel coronavirus (SARS-CoV-2), has swept the world and challenged its culture, economy, and health infrastructure. Forced emergence to find an effective vaccine to immunize people has led scientists to design and examine vaccine candidates all over the world. Until a vaccine...

journal_title：Journal of cellular physiology

authors： Rezaei M,Ziai SA,Fakhri S,Pouriran R

更新日期：2020-09-09 00:00:00

abstract：:DEAH box protein DHX33 has been found to be necessary for cell proliferation and early development of multicellular organisms. It plays diverse roles in regulating gene transcription, ribosome RNA synthesis, and protein translation. Dysregulation of DHX33 has been observed in various human cancers. In this study, we i...

journal_title：Journal of cellular physiology

authors： Su D,Yuan B,Su C,Zhang Y

更新日期：2019-01-26 00:00:00

abstract：:The effects of artificial cryptorchidism and its surgical reversal on spermatogenesis were examined in germ cell mutant, S1/+ and wild type, +/+, mice. In cryptorchid testes no difference was found between S1/+ and +/+ mice in the number of undifferentiated type A spermatogonia. The activity of type A spermatogonia in...

journal_title：Journal of cellular physiology

authors： Nishimune Y,Haneji T,Kitamura Y

更新日期：1980-10-01 00:00:00

abstract：:The level of adhesion molecules expressed at the endothelial cell surface is critical in the control of inflammation. Adenylate cyclase (AC) activity allowing cyclic adenosine monophosphate (cAMP) production can modulate the inflammatory process. We investigated the AC-dependent modulation of ICAM-1 surface expression...

journal_title：Journal of cellular physiology

authors： Bernot D,Peiretti F,Canault M,Juhan-Vague I,Nalbone G

更新日期：2005-02-01 00:00:00

abstract：:Several proteases and their specific inhibitors modulate the interdependent processes of cell migration and matrix proteolysis as part of the global program of trauma repair. Expression of plasminogen activator inhibitor type-1 (PAI-1), a serine protease inhibitor (SERPIN) important in the control of barrier proteolys...

journal_title：Journal of cellular physiology

authors： Providence KM,Higgins PJ

更新日期：2004-08-01 00:00:00

abstract：:The Giemsa banding pattern of the chromosomes has been analyzed in a line of transformed golden hamster cells, revertant and re-revertant cells and their tumors. The transformed and re-revertant cells were malignant in vivo and had gained an additional chromosome 5(7). Revertants with a suppression of malignancy lost ...

journal_title：Journal of cellular physiology

authors： Bloch-Shtacher N,Sachs L

更新日期：1976-01-01 00:00:00

abstract：:The regulation of hexose transport under glucose-starvation conditions was studied in cultured human skin fibroblasts. Glucose starvation enhanced the transport of 2-DG and 3-0-methyl-D-glucose (3-OMG) but not of L-glucose. Glucose-starvation enhanced transport was inhibited by cytochalasin B (10 microM). The starvati...

journal_title：Journal of cellular physiology

authors： Germinario RJ,Rockman H,Oliveira M,Manuel S,Taylor M

更新日期：1982-09-01 00:00:00

abstract：:Prostate cancer (PCa) is the second leading cause of death among American men. Increasing evidence has shown that long noncoding RNAs (lncRNAs) play important roles in tumorigenesis of PCa. In this study, we explored the biological functions of small nucleolar RNA host gene 12 (SNHG12) and investigated the interaction...

journal_title：Journal of cellular physiology

authors： Cheng G,Song Z,Liu Y,Xiao H,Ruan H,Cao Q,Wang K,Xiao W,Xiong Z,Liu D,Chen K,Zhang X

更新日期：2020-02-01 00:00:00

abstract：:Glioblastoma (GB) is the most common cancer in the brain and with an increasing incidence. Despite major advances in the field, there is no curative therapy for GB to date. Many solid tumors, including GB, experienced metabolic reprogramming in order to sustain uncontrolled proliferation, hypoxic conditions, and angio...

journal_title：Journal of cellular physiology

authors： Benedetti E,d'Angelo M,Ammazzalorso A,Gravina GL,Laezza C,Antonosante A,Panella G,Cinque B,Cristiano L,Dhez AC,Astarita C,Galzio R,Cifone MG,Ippoliti R,Amoroso R,Di Cesare E,Giordano A,Cimini A

更新日期：2017-06-01 00:00:00