MiR-499 Responsive Lethal Construct for Removal of Human Embryonic Stem Cells after Cardiac Differentiation.

abstract：:Cortical spreading depolarisation (CSD), the neural mechanism underlying migraine aura, may cause headache by sensitising the trigeminal system. Photophobia, the most bothersome accompanying symptom during migraine attacks, is more prevalent in migraine with aura than in migraine without aura. Whether CSD plays a role...

journal_title：Scientific reports

authors： Tang C,Unekawa M,Kitagawa S,Takizawa T,Kayama Y,Nakahara J,Shibata M

更新日期：2020-07-10 00:00:00

abstract：:The role of topical corticosteroids in management of Acanthamoeba keratitis (AK) remains controversial. Using a rabbit AK model, we investigated whether corticosteroid use is a risk factor of AK. Acanthamoeba (1 × 105/ml) was incubated with two densities of P. aeruginosa (PA; high-PA: 1 × 108/ml, low-PA: 3 × 105/ml) b...

journal_title：Scientific reports

authors： Nakagawa H,Koike N,Ehara T,Hattori T,Narimatsu A,Kumakura S,Goto H

更新日期：2019-09-06 00:00:00

abstract：:To elucidate the temporal changes in the radiocesium distribution in forests contaminated by the Fukushima Daiichi Nuclear Power Plant accident, we monitored the 137Cs concentration and inventory within forests from 2011 to 2015 across nine plots containing variable tree species and different contamination levels. The...

journal_title：Scientific reports

authors： Imamura N,Komatsu M,Ohashi S,Hashimoto S,Kajimoto T,Kaneko S,Takano T

更新日期：2017-08-15 00:00:00

abstract：:Geographical origin determination of white rice has become the major issue of food industry. However, there is still lack of a high-throughput method for rapidly and reproducibly differentiating the geographical origins of commercial white rice. In this study, we developed a method that employed lipidomics and deep le...

journal_title：Scientific reports

authors： Long NP,Lim DK,Mo C,Kim G,Kwon SW

更新日期：2017-08-17 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is a major global health burden. Functional exhaustion and numerical reduction of HBV-specific cytotoxic T lymphocytes (CTLs) in the liver and peripheral blood limit anti-HBV CTL activity in patients with chronic HBV infection (CHB). However, the ongoing anti-HBV CD8(+) T cell...

journal_title：Scientific reports

authors： Wang Y,Zhang Z,Ji D,Chen GF,Feng X,Gong LL,Guo J,Li ZW,Chen CF,Zhao BB,Li ZG,Li QJ,Yan HP,Sempowski G,Wang FS,He YW

更新日期：2015-07-22 00:00:00

abstract：:We propose the quantum simulation of the quantum Rabi model in all parameter regimes by means of detuned bichromatic sideband excitations of a single trapped ion. We show that current setups can reproduce, in particular, the ultrastrong and deep strong coupling regimes of such a paradigmatic light-matter interaction. ...

journal_title：Scientific reports

authors： Pedernales JS,Lizuain I,Felicetti S,Romero G,Lamata L,Solano E

更新日期：2015-10-20 00:00:00

abstract：:Quantum coherence and quantum correlations are important quantum resources for quantum computation and quantum information. In this paper, using entropy-based measures, we investigate the relationships between quantum correlated coherence, which is the coherence between subsystems, and two main kinds of quantum correl...

journal_title：Scientific reports

authors： Wang XL,Yue QL,Yu CH,Gao F,Qin SJ

更新日期：2017-09-21 00:00:00

abstract：:It has been hypothesised that speed information, encoded by 'speed cells', is important for updating spatial representation in the hippocampus and entorhinal cortex to reflect ongoing self-movement during locomotion. However, systematic characterisation of speed representation is still lacking. In this study, we compa...

journal_title：Scientific reports

authors： Iwase M,Kitanishi T,Mizuseki K

更新日期：2020-01-29 00:00:00

abstract：:Case-control genetic association studies typically ignore possible later disease onset in currently healthy subjects and assume that subjects with diseases equally contribute to the likelihood for inference, regardless of their onset age. Therefore, we used an event-history with risk-free model to simultaneously chara...

journal_title：Scientific reports

authors： Yang HC,Chen IC,Tsay YC,Li ZR,Chen CH,Hwu HG,Chen CH

更新日期：2017-05-16 00:00:00

abstract：:Interfacial charge transfer from photoexcited ruthenium-based N3 dye molecules into ZnO thin films received controversial interpretations. To identify the physical origin for the delayed electron transfer in ZnO compared to TiO2, we probe directly the electronic structure at both dye-semiconductor interfaces by applyi...

journal_title：Scientific reports

authors： Borgwardt M,Wilke M,Kampen T,Mähl S,Xiao M,Spiccia L,Lange KM,Kiyan IY,Aziz EF

更新日期：2016-04-13 00:00:00

abstract：:miR1444s are functionally significant miRNAs targeting polyphenol oxidase (PPO) genes for cleavage. MIR1444 genes were reported only in Populus trichocarpa. Through the computational analysis of 215 RNA-seq data, four whole genome sequences of Salicaceae species and deep sequencing of six P. trichocarpa small RNA libr...

journal_title：Scientific reports

authors： Wang M,Li C,Lu S

更新日期：2017-01-10 00:00:00

abstract：:The critical role of the regulatory elements at the 5' end of the HIV-1 genome in controlling the life cycle of HIV-1 indicates that this region significantly influences virus fitness and its biological properties. In this study, we performed a detailed characterization of strain-specific variability of sequences from...

journal_title：Scientific reports

authors： Mbondji-Wonje C,Dong M,Zhao J,Wang X,Nanfack A,Ragupathy V,Sanchez AM,Denny TN,Hewlett I

更新日期：2020-08-06 00:00:00

abstract：:Prolactin (PRL) is an anterior pituitary hormone with a broad range of functions. Its ability to stimulate lactogenesis, maternal behavior, growth and development, osmoregulation, and epithelial ion transport has been reported in many vertebrates. In our present study, we have targeted the zebrafish prl locus via tran...

journal_title：Scientific reports

authors： Shu Y,Lou Q,Dai Z,Dai X,He J,Hu W,Yin Z

更新日期：2016-01-04 00:00:00

abstract：:Macro- and micro-environmental factors modulate parasite loads in fish, determining parasitic abundances, diversity, and interaction dynamics. In this study, seasonal variations in larval ectoparasites on fish larvae in the northern Humboldt Current System (HCS) were evaluated using a delta-gamma generalized linear mo...

journal_title：Scientific reports

authors： Paredes LD,Landaeta MF,Molinet C,González MT

更新日期：2021-01-12 00:00:00

abstract：:The role of extractable pool of biochar in crop productivity and soil greenhouse gas (GHGs) emission is not yet clear. In this study, two biochars with and without extraction was added to a paddy before rice transplantation at 20 t·ha-1. Crop yield, plant traits and greenhouse gas emission monitored throughout a rice-...

journal_title：Scientific reports

authors： Korai PK,Xia X,Liu X,Bian R,Omondi MO,Nahayo A,Pan G

更新日期：2018-01-16 00:00:00

abstract：:Long-term high-fat diet (HFD) consumption leads to not only obese-insulin resistance, but also impaired left ventricular (LV) function. Vagus nerve stimulation (VNS) has been shown to exert cardioprotection. However, its effects on the heart and metabolic parameters under obese-insulin resistant condition is not known...

journal_title：Scientific reports

authors： Samniang B,Shinlapawittayatorn K,Chunchai T,Pongkan W,Kumfu S,Chattipakorn SC,KenKnight BH,Chattipakorn N

更新日期：2016-02-01 00:00:00

abstract：:Glutamine metabolism and the mechanistic target of rapamycin (mTOR) pathway are activated cooperatively in the differentiation and activation of inflammatory immune cells. But the combined inhibition of both pathways was rarely investigated. This study investigated how inhibiting both glutamine metabolism with 6-diazo...

journal_title：Scientific reports

authors： Ueda Y,Saegusa J,Okano T,Sendo S,Yamada H,Nishimura K,Morinobu A

更新日期：2019-04-23 00:00:00

abstract：:Seagrass meadows are threatened by coastal development and global change. In the face of these pressures, molecular techniques such as reverse transcription quantitative real-time PCR (RT-qPCR) have great potential to improve management of these ecosystems by allowing early detection of chronic stress. In RT-qPCR, the...

journal_title：Scientific reports

authors： Schliep M,Pernice M,Sinutok S,Bryant CV,York PH,Rasheed MA,Ralph PJ

更新日期：2015-11-23 00:00:00

abstract：:Spherical radioactive caesium (Cs)-bearing microparticles (CsMPs) were emitted during the Fukushima Dai-ichi Nuclear Power Plant (FDNPP) accident in March, 2011. The emission source (timing) and formation process of these particles remain unclear. In this study, the isotopic ratios of uranium (235U and 238U) and caesi...

journal_title：Scientific reports

authors： Kurihara Y,Takahata N,Yokoyama TD,Miura H,Kon Y,Takagi T,Higaki S,Yamaguchi N,Sano Y,Takahashi Y

更新日期：2020-02-24 00:00:00

abstract：:Endogenous K. pneumoniae endophthalmitis (EKE) has a higher incidence among East Asians, and the most common infectious source of EKE is pyogenic liver abscess (PLA). We investigate the risk factors for poor visual outcomes in patients with PLA-related EKE. The retrospective medical records of 104 patients (120 eyes) ...

journal_title：Scientific reports

authors： Chen YH,Li YH,Lin YJ,Chen YP,Wang NK,Chao AN,Liu L,Wu WC,Lai CC,Chen TL,Chen KJ

更新日期：2019-01-31 00:00:00

abstract：:Mankind is on the verge of a postantibiotic era. New concepts are needed in our battle to attenuate infectious diseases around the world and broad spectrum plant-inspired synergistic pharmaceutical preparations should find their place in the global fight against pathogenic microorganisms. To progress towards the disco...

journal_title：Scientific reports

authors： Rodrigues AMS,Eparvier V,Odonne G,Amusant N,Stien D,Houël E

更新日期：2019-06-19 00:00:00

abstract：:Global biodiversity hotspots (GBHs) are increasingly vulnerable to human stressors such as anthropogenic climate change, which will alter the ecology of these habitats, even where protected. The longleaf pine (Pinus palustris) ecosystem (LPE) of the North American Coastal Plain is a GBH where disturbances are integral...

journal_title：Scientific reports

authors： Zampieri NE,Pau S,Okamoto DK

更新日期：2020-05-21 00:00:00

abstract：:Probing the oligomeric state of abundant molecules, such as membrane proteins in intact cells, is essential, but has not been straightforward. We address this challenge with a simple counting strategy that is capable of reporting the oligomeric state of dense, membrane-bound protein complexes. It is based on single-mo...

journal_title：Scientific reports

authors： Fricke F,Beaudouin J,Eils R,Heilemann M

更新日期：2015-09-11 00:00:00

abstract：:Kidney transplantations using expanded criteria donors (ECD) are being increasingly adopted, but no consensus tools are available to evaluate donor kidney status. Beta-2 microglobulin (B2MG) is a marker of kidney function, and herein, we evaluate the usefulness of assessing B2MG to evaluate donor kidney status. Fifty-...

journal_title：Scientific reports

authors： Cha SW,Shin IS,Kim DG,Kim SH,Lee JY,Kim JS,Yang JW,Han BG,Choi SO

更新日期：2020-05-15 00:00:00

abstract：:We analyse theoretically the spatiotemporal dynamics of two incoherent counterpropagating Airy beams interacting in a photorefractive crystal under focusing conditions. For a large enough nonlinearity strength the interaction between the two Airy beams leads to light-induced waveguiding. The stability of the waveguide...

journal_title：Scientific reports

authors： Wiersma N,Marsal N,Sciamanna M,Wolfersberger D

更新日期：2015-08-28 00:00:00

abstract：:A biofilm has a unique structure composed of microorganisms, extracellular polymeric substances (EPSs), etc., and it is layered on a substrate in water. In material science, it is important to detect the biofilm formed on a surface to prevent biofouling. EPSs, the major component of the biofilm, mainly consist of poly...

journal_title：Scientific reports

authors： Tanaka N,Kogo T,Hirai N,Ogawa A,Kanematsu H,Takahara J,Awazu A,Fujita N,Haruzono Y,Ichida S,Tanaka Y

更新日期：2019-05-30 00:00:00

abstract：:The aberrant expression of human sodium iodide symporter (NIS) in breast cancer (BC) has raised the possibility of using targeted radioiodide therapy. Here we investigate modulation of endogenous, functional NIS expression by histone deacetylase inhibitors (HDACi) in vitro and in vivo. Luciferase reporter based initia...

journal_title：Scientific reports

authors： Kelkar MG,Senthilkumar K,Jadhav S,Gupta S,Ahn BC,De A

更新日期：2016-01-18 00:00:00

abstract：:Cartilage engineering that combines competent seeding cells and a compatible scaffold is increasingly gaining popularity and is potentially useful for the treatment of various bone and cartilage diseases. Intensive efforts have been made by researchers to improve the viability and functionality of seeding cells of eng...

journal_title：Scientific reports

authors： Ma Y,Li J,Yao Y,Wei D,Wang R,Wu Q

更新日期：2016-05-25 00:00:00

abstract：:Leaf flattening influences plant photosynthesis, thereby affecting product yield and quality. Here, we obtained a stably inherited leaf crinkled mutant (lcm), derived from the Chinese cabbage doubled haploid (DH) 'FT' line using EMS mutagenesis combined with isolated microspore culture. The crinkled phenotype was cont...

journal_title：Scientific reports

authors： Zhang M,Huang S,Gao Y,Fu W,Qu G,Zhao Y,Shi F,Liu Z,Feng H

更新日期：2020-08-18 00:00:00

abstract：:The recent discovery of magnetic skyrmion lattices initiated a surge of interest in the scientific community. Several novel phenomena have been shown to emerge from the interaction of conducting electrons with the skyrmion lattice, such as a topological Hall-effect and a spin-transfer torque at ultra-low current densi...

journal_title：Scientific reports

authors： Levatić I,Popčević P,Šurija V,Kruchkov A,Berger H,Magrez A,White JS,Rønnow HM,Živković I

更新日期：2016-02-19 00:00:00